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The map label for this gene is pfpI [H]

Identifier: 86751228

GI number: 86751228

Start: 4692425

End: 4692988

Strand: Reverse

Name: pfpI [H]

Synonym: RPB_4121

Alternate gene names: 86751228

Gene position: 4692988-4692425 (Counterclockwise)

Preceding gene: 86751229

Following gene: 86751226

Centisome position: 88.02

GC content: 63.65

Gene sequence:

>564_bases
ATGGCAGGCCAACTCGACGGCAAGCGCGTGCTCATTCTCGCCACCCACGGCTTCGAACAATCGGAACTCGAAGTGCCGCG
CGATCGGCTGAAGGCGGCGGGTGCGCAGGTCGACATCGTGTCGCCGGAGCAGGGCGAGATCAAGGGCTGGGACGGCAAGG
ATTGGGGCCGGCCGGTCAAGGTCGACAAGGCGCTCGGCTCGGCCAAGGCCGACGATTACGACGCGATCGTGCTGCCGGGC
GGACAGATCAATCCGGACTTGCTGCGCGTGAATGCCGATGCGCTGAAGCTGATCAAGTCGTTCTTCGATGCCGGCAAGAC
GGTGGCCGCGGTCTGCCATGCGCCGTGGCTCTTGATCGACACCGGCATCGCCAAGGGCCGCAAGATGACCTCCTACAATT
CGATCAAACAGGACGTGATCAATGCTGGCGCCAAGTGGGAAGACTCCGCCGTCGTCACCGACAACGGCGTGATCACGTCG
CGCAACCCGGGCGATCTCGAAGCGTTCTCGGCCAAGATCATCGAAGAGATCCGCGAAGGTAAGCATCAGCGCCGCGCGGC
GTGA

Upstream 100 bases:

>100_bases
GGCTCTCAGGATGACGGCGCTGATGCGTCCGGAACGATCACACGCGCTGTCGATTAGCGGAGCAGGCGGGGCGCAACGAA
AACGGATACGGAGATCCCTC

Downstream 100 bases:

>100_bases
GATCGAGCGGCGGGTGAGGTCAATTCGCTGATATCAAGTCGCGCGGATATCAAATCTCGATGGCCGGGCGCGTCCCGGCC
ATTCGAGCGTTGGGGTCTTC

Product: peptidase C56, PfpI

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAGQLDGKRVLILATHGFEQSELEVPRDRLKAAGAQVDIVSPEQGEIKGWDGKDWGRPVKVDKALGSAKADDYDAIVLPG
GQINPDLLRVNADALKLIKSFFDAGKTVAAVCHAPWLLIDTGIAKGRKMTSYNSIKQDVINAGAKWEDSAVVTDNGVITS
RNPGDLEAFSAKIIEEIREGKHQRRAA

Sequences:

>Translated_187_residues
MAGQLDGKRVLILATHGFEQSELEVPRDRLKAAGAQVDIVSPEQGEIKGWDGKDWGRPVKVDKALGSAKADDYDAIVLPG
GQINPDLLRVNADALKLIKSFFDAGKTVAAVCHAPWLLIDTGIAKGRKMTSYNSIKQDVINAGAKWEDSAVVTDNGVITS
RNPGDLEAFSAKIIEEIREGKHQRRAA
>Mature_186_residues
AGQLDGKRVLILATHGFEQSELEVPRDRLKAAGAQVDIVSPEQGEIKGWDGKDWGRPVKVDKALGSAKADDYDAIVLPGG
QINPDLLRVNADALKLIKSFFDAGKTVAAVCHAPWLLIDTGIAKGRKMTSYNSIKQDVINAGAKWEDSAVVTDNGVITSR
NPGDLEAFSAKIIEEIREGKHQRRAA

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI31543380, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI87082219, Length=165, Percent_Identity=38.1818181818182, Blast_Score=114, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17531319, Length=181, Percent_Identity=30.939226519337, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571932, Length=172, Percent_Identity=31.9767441860465, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20185; Mature: 20054

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQLDGKRVLILATHGFEQSELEVPRDRLKAAGAQVDIVSPEQGEIKGWDGKDWGRPVK
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEE
VDKALGSAKADDYDAIVLPGGQINPDLLRVNADALKLIKSFFDAGKTVAAVCHAPWLLID
HHHHHCCCCCCCCCEEEECCCCCCHHHEEECHHHHHHHHHHHHCCHHHHHHHHCCEEEEE
TGIAKGRKMTSYNSIKQDVINAGAKWEDSAVVTDNGVITSRNPGDLEAFSAKIIEEIREG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
KHQRRAA
HHHHCCC
>Mature Secondary Structure 
AGQLDGKRVLILATHGFEQSELEVPRDRLKAAGAQVDIVSPEQGEIKGWDGKDWGRPVK
CCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEE
VDKALGSAKADDYDAIVLPGGQINPDLLRVNADALKLIKSFFDAGKTVAAVCHAPWLLID
HHHHHCCCCCCCCCEEEECCCCCCHHHEEECHHHHHHHHHHHHCCHHHHHHHHCCEEEEE
TGIAKGRKMTSYNSIKQDVINAGAKWEDSAVVTDNGVITSRNPGDLEAFSAKIIEEIREG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHH
KHQRRAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA