Click here to switch to the map view.

The map label for this gene is cysQ [H]

Identifier: 86751030

GI number: 86751030

Start: 4474906

End: 4475742

Strand: Direct

Name: cysQ [H]

Synonym: RPB_3922

Alternate gene names: 86751030

Gene position: 4474906-4475742 (Clockwise)

Preceding gene: 86751023

Following gene: 86751032

Centisome position: 83.93

GC content: 71.68

Gene sequence:

>837_bases
ATGGGCAAGGGCCAGGCGTTCGGGACAGGACCGGTGATTTCGCACAACGACGCCGTCGCTTTGATGCAGCCATTGACCGA
GCTGGTGCTGCGCGCCGGGGCCGCGATCCTCGCCACCGACCGCTCCGACCCGGTCGAGCACAAGCCGGACGGCTCGCCGG
TGACCTCCGCCGACCTCGCCGCCGACCGCATCATCGCCGAGGGGCTGAAGCGGATCGCGCCCGACGTGCCGGCGCTGTCG
GAAGAGCGCTGCGACCTCGGCCGGCCGAATACCGGGAGCTTCTTCCTGGTCGATCCGCTCGACGGCACCAAGGAATACGT
CGCCGGGCGTGACGAATTCACCGTCAATCTGGCGCTGGTGACCGACGGCAAGCCGCTGCTCGGCATCGTCGGGGCGCCGG
CGCTGGGCCTGGTGTGGCGCGGCCTGGTCGGCCACGGCGCCGAGCGGCTGGCGGTCGACGCCGACGGCACCGGCTACGAC
ACGACGCCGATCCACACCCGGCCGATGCCGGCCGACGGAGCGCCGTGGGTCGTGGCGATCAGCCGGCTGCATCTCGACGA
ACGCACTCTGGCGTTCATCGCCGAGCGGCCAGGCGGCGTCCACGCGCGGATGGGATCGGCGCTGAAATTCTGCCGGATCG
CCGACGGCGCGGCCGACATCTATCCGCGGCTGTCGCCGACCTGCGAATGGGACATCGCCGCCGGCGCCGCCGTGGTGATC
GCCGCCGGCGGCGAACTGACCGACAGCAGCGGCCGGCCGCTGCGGTTCGACGAGCCGCGACCGAACTTCATCGTGCCGGA
ATTCATCGCCTGGGGGGATGCCCGGGCAGCAGCCTGA

Upstream 100 bases:

>100_bases
CGAGACGAATCAGCCATGTTGCATGGCTTGATACACTGCGGCCGGTTGCGCTGCCAACAGAGGGACCGGGACAACCGGCC
AGACGGAGGACGACGGGTTG

Downstream 100 bases:

>100_bases
GACGCCGCCGCGACAGCGCGCTATTCCGCCAGCGTGGCCAGGAGCGCCGGCCACTGCTGCTGCGCCTGGGCCAGAATGCG
CTCCGGATCGGCCGCGAAGG

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MGKGQAFGTGPVISHNDAVALMQPLTELVLRAGAAILATDRSDPVEHKPDGSPVTSADLAADRIIAEGLKRIAPDVPALS
EERCDLGRPNTGSFFLVDPLDGTKEYVAGRDEFTVNLALVTDGKPLLGIVGAPALGLVWRGLVGHGAERLAVDADGTGYD
TTPIHTRPMPADGAPWVVAISRLHLDERTLAFIAERPGGVHARMGSALKFCRIADGAADIYPRLSPTCEWDIAAGAAVVI
AAGGELTDSSGRPLRFDEPRPNFIVPEFIAWGDARAAA

Sequences:

>Translated_278_residues
MGKGQAFGTGPVISHNDAVALMQPLTELVLRAGAAILATDRSDPVEHKPDGSPVTSADLAADRIIAEGLKRIAPDVPALS
EERCDLGRPNTGSFFLVDPLDGTKEYVAGRDEFTVNLALVTDGKPLLGIVGAPALGLVWRGLVGHGAERLAVDADGTGYD
TTPIHTRPMPADGAPWVVAISRLHLDERTLAFIAERPGGVHARMGSALKFCRIADGAADIYPRLSPTCEWDIAAGAAVVI
AAGGELTDSSGRPLRFDEPRPNFIVPEFIAWGDARAAA
>Mature_277_residues
GKGQAFGTGPVISHNDAVALMQPLTELVLRAGAAILATDRSDPVEHKPDGSPVTSADLAADRIIAEGLKRIAPDVPALSE
ERCDLGRPNTGSFFLVDPLDGTKEYVAGRDEFTVNLALVTDGKPLLGIVGAPALGLVWRGLVGHGAERLAVDADGTGYDT
TPIHTRPMPADGAPWVVAISRLHLDERTLAFIAERPGGVHARMGSALKFCRIADGAADIYPRLSPTCEWDIAAGAAVVIA
AGGELTDSSGRPLRFDEPRPNFIVPEFIAWGDARAAA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=254, Percent_Identity=38.1889763779528, Blast_Score=144, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71995897, Length=171, Percent_Identity=29.2397660818713, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=171, Percent_Identity=29.2397660818713, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24664922, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29153; Mature: 29022

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGQAFGTGPVISHNDAVALMQPLTELVLRAGAAILATDRSDPVEHKPDGSPVTSADLA
CCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHH
ADRIIAEGLKRIAPDVPALSEERCDLGRPNTGSFFLVDPLDGTKEYVAGRDEFTVNLALV
HHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEE
TDGKPLLGIVGAPALGLVWRGLVGHGAERLAVDADGTGYDTTPIHTRPMPADGAPWVVAI
ECCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
SRLHLDERTLAFIAERPGGVHARMGSALKFCRIADGAADIYPRLSPTCEWDIAAGAAVVI
EHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCCEEEEE
AAGGELTDSSGRPLRFDEPRPNFIVPEFIAWGDARAAA
EECCCEECCCCCCEEECCCCCCEECHHHHCCCCHHCCC
>Mature Secondary Structure 
GKGQAFGTGPVISHNDAVALMQPLTELVLRAGAAILATDRSDPVEHKPDGSPVTSADLA
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHH
ADRIIAEGLKRIAPDVPALSEERCDLGRPNTGSFFLVDPLDGTKEYVAGRDEFTVNLALV
HHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEE
TDGKPLLGIVGAPALGLVWRGLVGHGAERLAVDADGTGYDTTPIHTRPMPADGAPWVVAI
ECCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
SRLHLDERTLAFIAERPGGVHARMGSALKFCRIADGAADIYPRLSPTCEWDIAAGAAVVI
EHHCCCCHHEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCCEEEEE
AAGGELTDSSGRPLRFDEPRPNFIVPEFIAWGDARAAA
EECCCEECCCCCCEEECCCCCCEECHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]