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The map label for this gene is ctrA [H]

Identifier: 86751020

GI number: 86751020

Start: 4465158

End: 4465859

Strand: Direct

Name: ctrA [H]

Synonym: RPB_3912

Alternate gene names: 86751020

Gene position: 4465158-4465859 (Clockwise)

Preceding gene: 86751015

Following gene: 86751021

Centisome position: 83.75

GC content: 59.26

Gene sequence:

>702_bases
ATGCGCGTATTGCTGATTGAAGATGACAGCGCGACTGCGCAGTCGATCGAATTGATGCTCAAATCCGAGAGTTTCAATGT
CTACACGACGGATCTCGGTGAAGAAGGCGTCGACCTCGGCAAATTGTACGATTACGACATCATCCTGCTCGATCTGAACC
TGCCGGACATGTCCGGTTACGACGTTCTCAAGCAGCTGCGGGTCTCCAAGATCAAAACCCCGATCCTGATCCTGTCCGGC
CTCGCCGGCATCGAGGACAAGGTGAAGGGTCTCGGCGTCGGCGCCGACGACTACATGACCAAGCCGTTCCACAAGGACGA
GCTGGTCGCCCGCATCCATGCCATCGTCCGCCGTTCCAAGGGCCATGCCCAATCGGTGATCCAGACCGGCGATCTCGTCG
TCAATCTCGACACCAAGACCGTCGAAGTCGGCGGCCAGCGCGTGCATCTGACCGGCAAGGAATACCAGATGCTGGAGCTG
CTCTCGCTCCGCAAGGGCACGACGCTGACCAAGGAAATGTTCCTGAACCATCTCTATGGCGGGATGGACGAGCCGGAACT
GAAGATCATCGACGTCTTCATCTGCAAGCTGCGCAAGAAGCTCGCCAACGCCTCCGACGGCCGCAACTTCATCGAAACGG
TGTGGGGCCGCGGCTACGTGCTGCGCGAACCGACCGAAGACGACGTCCGCATCCCGGCCTGA

Upstream 100 bases:

>100_bases
CATACCTTGTCAGGATCCGAATCAGTTGTTCAGAGGCGTTTCCAGTGCCGCAGGTAGTGCGGACGCCTGACGCCCGGAGC
GGCGCTATAAGGGGACTGGC

Downstream 100 bases:

>100_bases
TCGCTTTCGTCTTTCAAGGAGCGCCCGGTCAGGCGCTCACCTCCCGACTGAACCCCGCCGCAAATGGCGGGGTTTTTGTT
TGTGGGGGGAGCGCCGCCGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGVGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASDGRNFIETVWGRGYVLREPTEDDVRIPA

Sequences:

>Translated_233_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGVGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASDGRNFIETVWGRGYVLREPTEDDVRIPA
>Mature_233_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYDVLKQLRVSKIKTPILILSG
LAGIEDKVKGLGVGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASDGRNFIETVWGRGYVLREPTEDDVRIPA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.6071428571429, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.9775784753363, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.579185520362, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.2105263157895, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.2727272727273, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.6742081447964, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.0748898678414, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=30.4545454545455, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.2217194570136, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.2792792792793, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.5506607929515, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=144, Percent_Identity=28.4722222222222, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26079; Mature: 26079

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
DVLKQLRVSKIKTPILILSGLAGIEDKVKGLGVGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCC
GHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASDGRNFIETVWGRGYVLREPTEDDVRIPA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
DVLKQLRVSKIKTPILILSGLAGIEDKVKGLGVGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHCC
GHAQSVIQTGDLVVNLDTKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANASDGRNFIETVWGRGYVLREPTEDDVRIPA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA