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The map label for this gene is flhA [H]

Identifier: 86751014

GI number: 86751014

Start: 4458425

End: 4460554

Strand: Direct

Name: flhA [H]

Synonym: RPB_3906

Alternate gene names: 86751014

Gene position: 4458425-4460554 (Clockwise)

Preceding gene: 86751010

Following gene: 86751015

Centisome position: 83.62

GC content: 66.95

Gene sequence:

>2130_bases
ATGACGGATACGACGGTCGGCCAGGGCCCCGGCAGCAAGCTGCCCAGCCTGCGCGACATCGGCGGGATGCTGAAGCGCGG
CGATCTCGCGCTCGCCTTCGGCGTGCTCACCATCCTGGTCGTGCTGATCATGCCGCTGCCGGCGATCGTGCTCGACCTGT
TCCTGGCGATCTCGATCACGCTGTCGATCCTGATCCTGATGACCGCTCTGTTCATCCAGGCGCCGCTGGAATTCTCGTCG
TTTCCGACCGTGCTGCTGATCTCGACCATGCTGCGGCTGTCGCTGAACATGGCCTCGACCCGGCTGATCCTGTCGCACGG
CCATGAAGGCACCGCCGCCGCCGGCCACGTCATCGAGGCGTTCGGCAACTTCGTGATGGGCGGCAATTTCGTGATCGGGA
TCATCGTGTTCACGATCCTGATCATCGTCAACTTCGTGGTCATCACCAAGGGTTCGGGCCGCATCGCCGAAGTCGCGGCG
CGGTTCCAGCTCGACTCGATGCCCGGCAAGCAGATGGCGATCGACGCCGATCTCAGCGCCGGCCTGATCGACGAAGCCAC
CGCCAAGAAGCGCCGCCAGGAGCTCGAAGACGAGAGCGGCTTTTTCGGCGCGATGGACGGTGCCTCGAAATTCGTCCGCG
GCGACGCCATCGCCGGCCTCCTGGTGGTGTTCATCAACGTCATCGGCGGCATCATCATCGGCGTAGCCCAGCAGGGTCTC
TCCTTCGCCGAGGCCGGCCACACCTACACGCTGCTGACCGTCGGCGACGGCCTCGTCACGCAGGTGCCGGCGCTGATCGT
CTCCACCGCCGCCGGCCTCTTGGTGTCGAAGGCCGGCATCTCCGGCTCCGCCGACAAGGCGCTGATGAGCCAGCTGTCCG
GCTATCCGCAGGCGCTCGGCATGTCGGCCGGCGTGATGCTGGTGCTGGCCGCCCTGCCCGGCATCCCGACGCTGCCGTTC
CTGTTTCTCGGCGGCGGCGCGGCGTGGCTCGCGGTATCGGCGAGCAAGCGCAAGACCGCCGGCAAGGCCGCGGACGATGC
GGCGCTGGCGCTGGCGCCCGAGGCGGTCGCGGCCGCGGCCGCGGCGGCGGCCGAAGAGCCGATCAGCGCGGCGCTGAAGA
TCGACGATCTCAAGATCGAGCTCGGCTACGCGCTGCTGCCGCTGGTCAACGGCCCGGACGGCACCGACCGCCTCACCGAA
CAGATCAAGGCGCTGCGCCGTTCGCTGGCGATCGAAATGGGCTTCGTGATGCCGGCGGTGCGGATCCTCGACAACGTTCA
GCTCGAGGCCAACACCTACGTCATCAAGATCAAGGAAGTCGACGCCGGCAGCGGCCGGATCTGGCCGAACCAGTTCATGG
TGATGGACCCGGCTGGCGAACAGGTGACGGTGCCGGGCATCCACACCACCGAGCCGACCTTTGGATTACCTGCGACCTGG
GTCGACGCCGCCTTCAAGGAAGAGGCCTCGCTGAAGGGCTACACCGTGGTCGACGCCGCCACCGTGCTGTCGACGCACCT
GACCGAGCTCTTGAAGGGCAACATGTCGGACCTGTTGTCCTATGGCGAGACCCAGAAGCTGCTCAAGGAGCTGCCGGCGG
AGCAAGGCGAACTGGTCAAGGACATCGTGCCCGGCCAGATCACCGTCTCGGGCATCCAGCGCGTGCTGCAGCTGCTGCTC
GCCGAGCGTATCTCGATCCGCGACCTCTCGACCATCCTCGAAGGCGTCGCCGACGCGCTCGCCTTCTCGCGCAACCCGAA
CACCATCGTCGAGCACGTCCGCGCCAGGCTGGCGCGGCAGATCTGCGCGCAGAACACCTCGTACAACGGCTATTTGCCGC
TGATCGCGCTGTCGGCGAAATGGGAGCAGGCGTTCGCCGAATCGATCATCGGCCAGGGCGACGAACGCAGCCTGGCGATG
GCGCCGTCGAAGCTGTCCGAATTCATGACCGCGGTGCGCGACCGGTTCGAACAGGCCGCGCGCGAAGGCGAGGCCCCGGT
GCTCGTGACGTCGGCCTCGATCCGGCCGTTCGTGCGTTCGCTGGTGGAACGGTTCCGTGCCCAGACCACCGTGCTGTCGC
AGGCCGAGATTCATCCGCGCGCCCGGCTGAAGACGGTCGGCAGCGTATGA

Upstream 100 bases:

>100_bases
CGTGGACGCCAGTGCGGTGCCTCACATCGGAGTCGGCGACGCCGCGGTCGCGACGTGGGCGTTCGGCAAGCGCAGACGAC
AGCGGGAGAGAGCGGCGGAC

Downstream 100 bases:

>100_bases
CGGCCGTCAAGCAGGTCCGCGCGGTCGGGTTCGACCGCGGCATTTTCGCCACAGACAAGCCAAAGGATTGATGAGTCGTC
GAGCAGCGGTCAATCCAACA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MTDTTVGQGPGSKLPSLRDIGGMLKRGDLALAFGVLTILVVLIMPLPAIVLDLFLAISITLSILILMTALFIQAPLEFSS
FPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGNFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAA
RFQLDSMPGKQMAIDADLSAGLIDEATAKKRRQELEDESGFFGAMDGASKFVRGDAIAGLLVVFINVIGGIIIGVAQQGL
SFAEAGHTYTLLTVGDGLVTQVPALIVSTAAGLLVSKAGISGSADKALMSQLSGYPQALGMSAGVMLVLAALPGIPTLPF
LFLGGGAAWLAVSASKRKTAGKAADDAALALAPEAVAAAAAAAAEEPISAALKIDDLKIELGYALLPLVNGPDGTDRLTE
QIKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGSGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATW
VDAAFKEEASLKGYTVVDAATVLSTHLTELLKGNMSDLLSYGETQKLLKELPAEQGELVKDIVPGQITVSGIQRVLQLLL
AERISIRDLSTILEGVADALAFSRNPNTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGDERSLAM
APSKLSEFMTAVRDRFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVLSQAEIHPRARLKTVGSV

Sequences:

>Translated_709_residues
MTDTTVGQGPGSKLPSLRDIGGMLKRGDLALAFGVLTILVVLIMPLPAIVLDLFLAISITLSILILMTALFIQAPLEFSS
FPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGNFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAA
RFQLDSMPGKQMAIDADLSAGLIDEATAKKRRQELEDESGFFGAMDGASKFVRGDAIAGLLVVFINVIGGIIIGVAQQGL
SFAEAGHTYTLLTVGDGLVTQVPALIVSTAAGLLVSKAGISGSADKALMSQLSGYPQALGMSAGVMLVLAALPGIPTLPF
LFLGGGAAWLAVSASKRKTAGKAADDAALALAPEAVAAAAAAAAEEPISAALKIDDLKIELGYALLPLVNGPDGTDRLTE
QIKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGSGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATW
VDAAFKEEASLKGYTVVDAATVLSTHLTELLKGNMSDLLSYGETQKLLKELPAEQGELVKDIVPGQITVSGIQRVLQLLL
AERISIRDLSTILEGVADALAFSRNPNTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGDERSLAM
APSKLSEFMTAVRDRFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVLSQAEIHPRARLKTVGSV
>Mature_708_residues
TDTTVGQGPGSKLPSLRDIGGMLKRGDLALAFGVLTILVVLIMPLPAIVLDLFLAISITLSILILMTALFIQAPLEFSSF
PTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEAFGNFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAAR
FQLDSMPGKQMAIDADLSAGLIDEATAKKRRQELEDESGFFGAMDGASKFVRGDAIAGLLVVFINVIGGIIIGVAQQGLS
FAEAGHTYTLLTVGDGLVTQVPALIVSTAAGLLVSKAGISGSADKALMSQLSGYPQALGMSAGVMLVLAALPGIPTLPFL
FLGGGAAWLAVSASKRKTAGKAADDAALALAPEAVAAAAAAAAEEPISAALKIDDLKIELGYALLPLVNGPDGTDRLTEQ
IKALRRSLAIEMGFVMPAVRILDNVQLEANTYVIKIKEVDAGSGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATWV
DAAFKEEASLKGYTVVDAATVLSTHLTELLKGNMSDLLSYGETQKLLKELPAEQGELVKDIVPGQITVSGIQRVLQLLLA
ERISIRDLSTILEGVADALAFSRNPNTIVEHVRARLARQICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGDERSLAMA
PSKLSEFMTAVRDRFEQAAREGEAPVLVTSASIRPFVRSLVERFRAQTTVLSQAEIHPRARLKTVGSV

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=677, Percent_Identity=42.0974889217134, Blast_Score=517, Evalue=1e-148,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74879; Mature: 74748

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTVGQGPGSKLPSLRDIGGMLKRGDLALAFGVLTILVVLIMPLPAIVLDLFLAISIT
CCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILILMTALFIQAPLEFSSFPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FGNFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAARFQLDSMPGKQMAIDADLSA
HCCHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLIDEATAKKRRQELEDESGFFGAMDGASKFVRGDAIAGLLVVFINVIGGIIIGVAQQGL
CHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFAEAGHTYTLLTVGDGLVTQVPALIVSTAAGLLVSKAGISGSADKALMSQLSGYPQALG
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHC
MSAGVMLVLAALPGIPTLPFLFLGGGAAWLAVSASKRKTAGKAADDAALALAPEAVAAAA
CHHHHHHHHHHCCCCCCCHHHHCCCCHHEEEEECHHHHCCCCCCCCCHHHCCHHHHHHHH
AAAAEEPISAALKIDDLKIELGYALLPLVNGPDGTDRLTEQIKALRRSLAIEMGFVMPAV
HHHHHCCHHHHEEEECEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RILDNVQLEANTYVIKIKEVDAGSGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATW
HHHHCCEEECCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCHHH
VDAAFKEEASLKGYTVVDAATVLSTHLTELLKGNMSDLLSYGETQKLLKELPAEQGELVK
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCHHHH
DIVPGQITVSGIQRVLQLLLAERISIRDLSTILEGVADALAFSRNPNTIVEHVRARLARQ
HHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGDERSLAMAPSKLSEFMTAVRDRFEQAA
HHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
REGEAPVLVTSASIRPFVRSLVERFRAQTTVLSQAEIHPRARLKTVGSV
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
TDTTVGQGPGSKLPSLRDIGGMLKRGDLALAFGVLTILVVLIMPLPAIVLDLFLAISIT
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSILILMTALFIQAPLEFSSFPTVLLISTMLRLSLNMASTRLILSHGHEGTAAAGHVIEA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FGNFVMGGNFVIGIIVFTILIIVNFVVITKGSGRIAEVAARFQLDSMPGKQMAIDADLSA
HCCHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLIDEATAKKRRQELEDESGFFGAMDGASKFVRGDAIAGLLVVFINVIGGIIIGVAQQGL
CHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFAEAGHTYTLLTVGDGLVTQVPALIVSTAAGLLVSKAGISGSADKALMSQLSGYPQALG
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHC
MSAGVMLVLAALPGIPTLPFLFLGGGAAWLAVSASKRKTAGKAADDAALALAPEAVAAAA
CHHHHHHHHHHCCCCCCCHHHHCCCCHHEEEEECHHHHCCCCCCCCCHHHCCHHHHHHHH
AAAAEEPISAALKIDDLKIELGYALLPLVNGPDGTDRLTEQIKALRRSLAIEMGFVMPAV
HHHHHCCHHHHEEEECEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RILDNVQLEANTYVIKIKEVDAGSGRIWPNQFMVMDPAGEQVTVPGIHTTEPTFGLPATW
HHHHCCEEECCEEEEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCHHH
VDAAFKEEASLKGYTVVDAATVLSTHLTELLKGNMSDLLSYGETQKLLKELPAEQGELVK
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCCHHHH
DIVPGQITVSGIQRVLQLLLAERISIRDLSTILEGVADALAFSRNPNTIVEHVRARLARQ
HHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ICAQNTSYNGYLPLIALSAKWEQAFAESIIGQGDERSLAMAPSKLSEFMTAVRDRFEQAA
HHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
REGEAPVLVTSASIRPFVRSLVERFRAQTTVLSQAEIHPRARLKTVGSV
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938923; 1732219; 11259647 [H]