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The map label for this gene is 86750910

Identifier: 86750910

GI number: 86750910

Start: 4336545

End: 4338686

Strand: Direct

Name: 86750910

Synonym: RPB_3801

Alternate gene names: NA

Gene position: 4336545-4338686 (Clockwise)

Preceding gene: 86750906

Following gene: 86750927

Centisome position: 81.34

GC content: 68.21

Gene sequence:

>2142_bases
ATGCAGCCCGGACGCAACAAGGCCCCCAGCGCCTCGCCGCCCTACGACAAATCCTACGAGCCCGTGCTGCTGCTGATGCG
GGCGCGGGTGATGCACCAGGCCGGGCAATACGACGAGGCGAAATCCGCCTACAAGAAGGTGCTGAAGAAGAGCCCGAACA
ACTTCCAGGCGCTGCACTTTCTCGGCCTCGCCGAATTTCAGACCGGACATTTCGACGCCGGCATCCGCTCGCTGAAGCGC
GCGCTGATCGAAGACCCGAAATCGGCGCAGGCGCAGTCCGACCTCGGCAGCGTGCTCAACGCCGCGCAGCGCTACGACGA
AGCGCTGGTCGCCTGCGACAAGGCGATCGCGCTGGATCCGGCGCTCGCCTTCGCCCATGCCAATCGCGGCAACGTGCTGA
TCACGCTCGGCCGCTACGACGAAGCGGTCGCCAGCCTCGACCGGGCGCTCGAGCTCGTTCCGGACCACACCGACACCTGG
AACGACCGCGGCAACGCGCTGCACAAGCTCGGCCGCTACGACGAGGCGCTGAACAGCTACGCCCAGGCGATCAGGATCGA
TCCGCTGCACGACGTCGCCTTCATGAACCAGGCGACCACGCTGAAGGAGATGAAGCAGTTCGACCTGGCGCTGGCGAGCT
ACGACCGCGCGCTGTCGATCGGCAAGCGACCGATCGACGCCGGCATCGCGCGCGCCGATCTGCTGCTGCAGATGAAGAAC
GTCGAGGGCGCGCTCGCGACCTGCACGGCGCTGCTGAAGATCGAGCCCGACTTCGTCCCCGCCCTGACGCTGCTCGGCAA
TTGCATGGCCTCGCTCGGCGACGCCGACACCGCGACCGCGCTGCACGGCCGCGCGCTGGCGCTGAAGCCGGACTACGAGC
CGGCAATTTCCAGCCGGATCTTCTCGATGGACTTCTGCTCCGATGCGGACTTCCAGTCGCAGCAGGCCGCGCGCGCGGAC
TGGTGGAAGCACGTCGGCGCGCGGCTGTACAAGAGCCATGCGGCGCCGCTCGCCAACGATCGCGACCCAGAGCGCCGCCT
GGTGGTCGGTTACGTCTCGGCCGATTTCCGCCAGCATTCCGCGGCGTTCTCGTTCCGCCCGGTGATCGAGAATCACGACC
GCACGCAGGTCGAAGTGATCTGCTACTCCGGCGTCGTGCTGCCCGACGCCGCGACCAAATCGTTCGAGGCGATCGCCGAC
AGGTGGCGCGACTCCTCGCAGTGGACCGACGCCAGGCTCGCCGACACGATCCGCGCCGACAAGGTCGACATCCTGATCGA
CCTGTCGGGCCATTCGGCCGGCAACCGCCTGCGGGTGTTCGCGCGAAAGCCGGCGCCGGTGCAGGTCACCGCCTGGGGCC
ACGCCACCGGCACCGGCCTGCCGGTGATCGACTATCTGCTGGCCGATCCGGTCGCGGTACCCAACGAGGTTCGACAGTTC
TATGCGGAAGCGATCTACGATCTGCCCTCGATCGTGATCATCGAACCGCCGCCTGCGGGGCTGCATGCCACCGAGCTGCC
GTTCGACCGCAACGGCTATCTGACCTACGGCTCGCTCAACCGCATCAGCAAGATCTCGGATGCGGCGATCGCGGCCTGGG
CGCGGATCATGACCGGCAATCCGACCTCGCGGCTGATCCTGAAGGATCACCAGATCGACGATCCCGCCGTGCGACAGACG
CTGCTCGACAAGTTCGCCGCGCAAGGCATCGCCGCCGAACGCCTCACGCTGCTCGGTTCGACGTCGCGGCAGGAGCATCT
GGAGACGCTGCAACAGATCGACCTCGGCCTCGATCCGTTCCCGCAAGCCGGCGGCGTTTCGACCTGGGAAGCGCTGCATA
TGGGCGTGCCGGTGGTGAGCCGGCTCGGCAACACCGTCGCCAGCCGGGTTGGCTCTGCGATCCTGTCGGCCGCCGGCCTG
CCGGACTTCATCGCCACCAGCGAAGAGCGCTACATCGCGATCGCGCTCGATCCGGATCGCGAGCGGCTGCGCGCGATCCG
CCGCGGCCTGCCCGCCTTCATCGCCGAGCGCTGCGGCCCCGCCGCCTACACCCGCGCCGTCGAGGACGCCTACCGCACGA
TGTGGCGCCGCTGGTGCGCGACGCCGGCGGACGCGAAGCCGGCGGACGGCAAGCGGCGCTGA

Upstream 100 bases:

>100_bases
TTACGCGAACCTCCGAGTATCCGCGCGATCTACCCGATCGACTCCAAGGTGCGTAGGATCGCCCGACGAGCAGTCTTCCT
CAGGCCGATTCGGAAACGCC

Downstream 100 bases:

>100_bases
GGTCGGGATACACGACCTACCACTACGCACTACCACCACGCACAGCGTCATCCTGAGGCGCCCGTCGGGCCGCGCCCTGC
GCGGCGCGGCGGGCCTCGAA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MQPGRNKAPSASPPYDKSYEPVLLLMRARVMHQAGQYDEAKSAYKKVLKKSPNNFQALHFLGLAEFQTGHFDAGIRSLKR
ALIEDPKSAQAQSDLGSVLNAAQRYDEALVACDKAIALDPALAFAHANRGNVLITLGRYDEAVASLDRALELVPDHTDTW
NDRGNALHKLGRYDEALNSYAQAIRIDPLHDVAFMNQATTLKEMKQFDLALASYDRALSIGKRPIDAGIARADLLLQMKN
VEGALATCTALLKIEPDFVPALTLLGNCMASLGDADTATALHGRALALKPDYEPAISSRIFSMDFCSDADFQSQQAARAD
WWKHVGARLYKSHAAPLANDRDPERRLVVGYVSADFRQHSAAFSFRPVIENHDRTQVEVICYSGVVLPDAATKSFEAIAD
RWRDSSQWTDARLADTIRADKVDILIDLSGHSAGNRLRVFARKPAPVQVTAWGHATGTGLPVIDYLLADPVAVPNEVRQF
YAEAIYDLPSIVIIEPPPAGLHATELPFDRNGYLTYGSLNRISKISDAAIAAWARIMTGNPTSRLILKDHQIDDPAVRQT
LLDKFAAQGIAAERLTLLGSTSRQEHLETLQQIDLGLDPFPQAGGVSTWEALHMGVPVVSRLGNTVASRVGSAILSAAGL
PDFIATSEERYIAIALDPDRERLRAIRRGLPAFIAERCGPAAYTRAVEDAYRTMWRRWCATPADAKPADGKRR

Sequences:

>Translated_713_residues
MQPGRNKAPSASPPYDKSYEPVLLLMRARVMHQAGQYDEAKSAYKKVLKKSPNNFQALHFLGLAEFQTGHFDAGIRSLKR
ALIEDPKSAQAQSDLGSVLNAAQRYDEALVACDKAIALDPALAFAHANRGNVLITLGRYDEAVASLDRALELVPDHTDTW
NDRGNALHKLGRYDEALNSYAQAIRIDPLHDVAFMNQATTLKEMKQFDLALASYDRALSIGKRPIDAGIARADLLLQMKN
VEGALATCTALLKIEPDFVPALTLLGNCMASLGDADTATALHGRALALKPDYEPAISSRIFSMDFCSDADFQSQQAARAD
WWKHVGARLYKSHAAPLANDRDPERRLVVGYVSADFRQHSAAFSFRPVIENHDRTQVEVICYSGVVLPDAATKSFEAIAD
RWRDSSQWTDARLADTIRADKVDILIDLSGHSAGNRLRVFARKPAPVQVTAWGHATGTGLPVIDYLLADPVAVPNEVRQF
YAEAIYDLPSIVIIEPPPAGLHATELPFDRNGYLTYGSLNRISKISDAAIAAWARIMTGNPTSRLILKDHQIDDPAVRQT
LLDKFAAQGIAAERLTLLGSTSRQEHLETLQQIDLGLDPFPQAGGVSTWEALHMGVPVVSRLGNTVASRVGSAILSAAGL
PDFIATSEERYIAIALDPDRERLRAIRRGLPAFIAERCGPAAYTRAVEDAYRTMWRRWCATPADAKPADGKRR
>Mature_713_residues
MQPGRNKAPSASPPYDKSYEPVLLLMRARVMHQAGQYDEAKSAYKKVLKKSPNNFQALHFLGLAEFQTGHFDAGIRSLKR
ALIEDPKSAQAQSDLGSVLNAAQRYDEALVACDKAIALDPALAFAHANRGNVLITLGRYDEAVASLDRALELVPDHTDTW
NDRGNALHKLGRYDEALNSYAQAIRIDPLHDVAFMNQATTLKEMKQFDLALASYDRALSIGKRPIDAGIARADLLLQMKN
VEGALATCTALLKIEPDFVPALTLLGNCMASLGDADTATALHGRALALKPDYEPAISSRIFSMDFCSDADFQSQQAARAD
WWKHVGARLYKSHAAPLANDRDPERRLVVGYVSADFRQHSAAFSFRPVIENHDRTQVEVICYSGVVLPDAATKSFEAIAD
RWRDSSQWTDARLADTIRADKVDILIDLSGHSAGNRLRVFARKPAPVQVTAWGHATGTGLPVIDYLLADPVAVPNEVRQF
YAEAIYDLPSIVIIEPPPAGLHATELPFDRNGYLTYGSLNRISKISDAAIAAWARIMTGNPTSRLILKDHQIDDPAVRQT
LLDKFAAQGIAAERLTLLGSTSRQEHLETLQQIDLGLDPFPQAGGVSTWEALHMGVPVVSRLGNTVASRVGSAILSAAGL
PDFIATSEERYIAIALDPDRERLRAIRRGLPAFIAERCGPAAYTRAVEDAYRTMWRRWCATPADAKPADGKRR

Specific function: Unknown

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=585, Percent_Identity=26.6666666666667, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI32307148, Length=585, Percent_Identity=26.6666666666667, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI301336134, Length=196, Percent_Identity=27.0408163265306, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI83415184, Length=196, Percent_Identity=27.0408163265306, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI167466177, Length=153, Percent_Identity=24.8366013071895, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI167466175, Length=153, Percent_Identity=24.8366013071895, Blast_Score=68, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=486, Percent_Identity=27.9835390946502, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115532690, Length=486, Percent_Identity=27.9835390946502, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25146105, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193210476, Length=194, Percent_Identity=23.7113402061856, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319387, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17647755, Length=482, Percent_Identity=28.6307053941909, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24585827, Length=482, Percent_Identity=28.6307053941909, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24585829, Length=482, Percent_Identity=28.6307053941909, Blast_Score=168, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 78169; Mature: 78169

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPGRNKAPSASPPYDKSYEPVLLLMRARVMHQAGQYDEAKSAYKKVLKKSPNNFQALHF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
LGLAEFQTGHFDAGIRSLKRALIEDPKSAQAQSDLGSVLNAAQRYDEALVACDKAIALDP
HHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAFAHANRGNVLITLGRYDEAVASLDRALELVPDHTDTWNDRGNALHKLGRYDEALNSY
HHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AQAIRIDPLHDVAFMNQATTLKEMKQFDLALASYDRALSIGKRPIDAGIARADLLLQMKN
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
VEGALATCTALLKIEPDFVPALTLLGNCMASLGDADTATALHGRALALKPDYEPAISSRI
CCHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECCCCCHHHHHHE
FSMDFCSDADFQSQQAARADWWKHVGARLYKSHAAPLANDRDPERRLVVGYVSADFRQHS
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHH
AAFSFRPVIENHDRTQVEVICYSGVVLPDAATKSFEAIADRWRDSSQWTDARLADTIRAD
CCCEECHHHCCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
KVDILIDLSGHSAGNRLRVFARKPAPVQVTAWGHATGTGLPVIDYLLADPVAVPNEVRQF
CEEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHH
YAEAIYDLPSIVIIEPPPAGLHATELPFDRNGYLTYGSLNRISKISDAAIAAWARIMTGN
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
PTSRLILKDHQIDDPAVRQTLLDKFAAQGIAAERLTLLGSTSRQEHLETLQQIDLGLDPF
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
PQAGGVSTWEALHMGVPVVSRLGNTVASRVGSAILSAAGLPDFIATSEERYIAIALDPDR
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEECCCH
ERLRAIRRGLPAFIAERCGPAAYTRAVEDAYRTMWRRWCATPADAKPADGKRR
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPGRNKAPSASPPYDKSYEPVLLLMRARVMHQAGQYDEAKSAYKKVLKKSPNNFQALHF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
LGLAEFQTGHFDAGIRSLKRALIEDPKSAQAQSDLGSVLNAAQRYDEALVACDKAIALDP
HHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAFAHANRGNVLITLGRYDEAVASLDRALELVPDHTDTWNDRGNALHKLGRYDEALNSY
HHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AQAIRIDPLHDVAFMNQATTLKEMKQFDLALASYDRALSIGKRPIDAGIARADLLLQMKN
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
VEGALATCTALLKIEPDFVPALTLLGNCMASLGDADTATALHGRALALKPDYEPAISSRI
CCHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECCCCCHHHHHHE
FSMDFCSDADFQSQQAARADWWKHVGARLYKSHAAPLANDRDPERRLVVGYVSADFRQHS
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHH
AAFSFRPVIENHDRTQVEVICYSGVVLPDAATKSFEAIADRWRDSSQWTDARLADTIRAD
CCCEECHHHCCCCCCEEEEEEECCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
KVDILIDLSGHSAGNRLRVFARKPAPVQVTAWGHATGTGLPVIDYLLADPVAVPNEVRQF
CEEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHH
YAEAIYDLPSIVIIEPPPAGLHATELPFDRNGYLTYGSLNRISKISDAAIAAWARIMTGN
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
PTSRLILKDHQIDDPAVRQTLLDKFAAQGIAAERLTLLGSTSRQEHLETLQQIDLGLDPF
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
PQAGGVSTWEALHMGVPVVSRLGNTVASRVGSAILSAAGLPDFIATSEERYIAIALDPDR
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEECCCH
ERLRAIRRGLPAFIAERCGPAAYTRAVEDAYRTMWRRWCATPADAKPADGKRR
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]