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The map label for this gene is coxS [H]

Identifier: 86750788

GI number: 86750788

Start: 4218338

End: 4218835

Strand: Reverse

Name: coxS [H]

Synonym: RPB_3678

Alternate gene names: 86750788

Gene position: 4218835-4218338 (Counterclockwise)

Preceding gene: 86750789

Following gene: 86750787

Centisome position: 79.13

GC content: 63.86

Gene sequence:

>498_bases
ATGAGAGGGCCGATGGCCAAGATTTCCCTGATCGTGAATGGCAATCCCGTGACCGCGAATGTCGATCCGCGCACGCTGCT
GGTGCAGTTTCTGCGCGAGCATCTGCGGCTCACGGGCACCCATGTCGGCTGCGACACGTCGCAGTGCGGCGCCTGCGTCG
TGCATCTCGACGGCAAGGCGGTGAAGTCCTGCACCACGCTGGCGGTGATGGCGGACGGCCATGAAGTGACGACGATCGAG
GGACTGGCCGCCGATGGCGCGCCGCTGCATCCGATGCAGGAGGCATTTCGCGAACATCACGGGCTGCAATGCGGTTTCTG
CACGCCGGGCATGATCATGACCGCGGTCGATCTGGTGCACCGCAAGGGGCATGAGCTGTCAGACGCCACGATTCGCGAGG
AGCTCGAAGGCAATCTGTGCCGCTGCACCGGCTATCAGAACATCGTGCTGTCGATCGCGGCCGGCGCCAAGGCGATGGCG
AATTCCGATCTCGCGTAA

Upstream 100 bases:

>100_bases
GATCCGAGGTTGCCGATCCGGGTGTTGCCCCCTAAGATATGTTCAAGAAACACAACTAAGACGCGAGCTGACTGCCGTGC
AACGCGGCGGTGTGACATGA

Downstream 100 bases:

>100_bases
CCAGTTTCGGGCAACGATCAAAGCGCAGGCCGAGCGGCCCAGGGAAGCTCAATGTACGATTTCAAATATCACCGCCCCGC
GACGGTCCGCCAGGCCGCGA

Product: carbon-monoxide dehydrogenase small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRGPMAKISLIVNGNPVTANVDPRTLLVQFLREHLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVTTIE
GLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSDATIREELEGNLCRCTGYQNIVLSIAAGAKAMA
NSDLA

Sequences:

>Translated_165_residues
MRGPMAKISLIVNGNPVTANVDPRTLLVQFLREHLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVTTIE
GLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSDATIREELEGNLCRCTGYQNIVLSIAAGAKAMA
NSDLA
>Mature_165_residues
MRGPMAKISLIVNGNPVTANVDPRTLLVQFLREHLRLTGTHVGCDTSQCGACVVHLDGKAVKSCTTLAVMADGHEVTTIE
GLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVHRKGHELSDATIREELEGNLCRCTGYQNIVLSIAAGAKAMA
NSDLA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=162, Percent_Identity=40.1234567901235, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI71773480, Length=155, Percent_Identity=37.4193548387097, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=45.5089820359281, Blast_Score=129, Evalue=7e-32,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=43.8356164383562, Blast_Score=113, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=39.4904458598726, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=157, Percent_Identity=35.6687898089172, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=36.3057324840764, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737937, Length=162, Percent_Identity=41.358024691358, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24647197, Length=155, Percent_Identity=36.7741935483871, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647201, Length=148, Percent_Identity=36.4864864864865, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24647199, Length=145, Percent_Identity=37.9310344827586, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.8024691358025, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647193, Length=133, Percent_Identity=38.3458646616541, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17515; Mature: 17515

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPMAKISLIVNGNPVTANVDPRTLLVQFLREHLRLTGTHVGCDTSQCGACVVHLDGKA
CCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHH
VKSCTTLAVMADGHEVTTIEGLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVH
HHHHEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHH
RKGHELSDATIREELEGNLCRCTGYQNIVLSIAAGAKAMANSDLA
HCCCCCCHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHCCCCCC
>Mature Secondary Structure
MRGPMAKISLIVNGNPVTANVDPRTLLVQFLREHLRLTGTHVGCDTSQCGACVVHLDGKA
CCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHH
VKSCTTLAVMADGHEVTTIEGLAADGAPLHPMQEAFREHHGLQCGFCTPGMIMTAVDLVH
HHHHEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHH
RKGHELSDATIREELEGNLCRCTGYQNIVLSIAAGAKAMANSDLA
HCCCCCCHHHHHHHHCCCEEEECCCCEEEEECCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]