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The map label for this gene is ygbM [C]

Identifier: 86750721

GI number: 86750721

Start: 4147160

End: 4147942

Strand: Reverse

Name: ygbM [C]

Synonym: RPB_3611

Alternate gene names: 86750721

Gene position: 4147942-4147160 (Counterclockwise)

Preceding gene: 86750722

Following gene: 86750720

Centisome position: 77.8

GC content: 65.13

Gene sequence:

>783_bases
ATGCCGCGCTTTGCCGCTAATCTCAGCCTGATGTTCAACGAGCACGCTTTCCTCGATCGCTTCGATGCCGCGGCAGCCGC
GGGTTTTACCGCGGTGGAATTTCTGTTTCCGTATGATCACAGGCCCGACGACATCGCCGAGCGGCTGAGGCGCAACAATC
TCATGCAGGCGCTGTTCAACCTGCCACCGGGCGATTGGGCCGGCGGCGAAAAAGGCTTCGCGGCGCGGCCGGACAAATTC
GAGGACCTGCAGCAGAGCCTGCACACCGCGCTGCCTTATGTGTTGGCGACCGGGGTCAGGCGCGTGCATCTGATGGCCGG
GCTCGCCGACCGCCACGACGGCGCGGCGGCGCTGGCGTTTCGTCGGTCGCTCGCGGTCGCGGCGCATTTCTTCGCGCCGC
ACGGCATCGACGTGCTGATCGAGCCGCTCAACCAGCGCGACGTGCCGGGCTATTTCCTCGACGATTTCGGTTTTGCGCAC
GACCTGATCCGCGAATTGCAGATTCCGAACCTCATGCTGCAGTTCGACGTCTATCACTGCCAGATCCTGCACGGCGACGT
GGTGATGCGGCTGCGCGAGATGATGCCGACGATCGGCCACATCCAGATCGCCAGCGTGCCGTCGCGCCACGAGCCCGACG
GCGAGGAGCTGAACTATCCGTTCCTGTTCGCTGAACTCGACCGGCTCGGCTATGCCGGCTTCGTCGGCGCGGAATATCGG
CCGCGTGGCGCCACGCTCGATGGGCTCGGCTGGTTCGCGCCCTTTGCCGGAGCGCGGATGTGA

Upstream 100 bases:

>100_bases
TCTTTGTTCGGAATAATTTGCACGAAATCGTTGCCTTGGCAACAGTCTCCTCGTCATGAGGGCCAAGCGGCTCGAGGGCC
GATAGAGCAGGGACCGATCG

Downstream 100 bases:

>100_bases
CGCTGGCGCTCGGCTGCATCGCGGACGACTGCACCGGGGCGTCGGATTCGCCGACACCTCGCGGTGAAGCCGTCATCCGT
TCGTCGTCGAGCCCCCTGCC

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MPRFAANLSLMFNEHAFLDRFDAAAAAGFTAVEFLFPYDHRPDDIAERLRRNNLMQALFNLPPGDWAGGEKGFAARPDKF
EDLQQSLHTALPYVLATGVRRVHLMAGLADRHDGAAALAFRRSLAVAAHFFAPHGIDVLIEPLNQRDVPGYFLDDFGFAH
DLIRELQIPNLMLQFDVYHCQILHGDVVMRLREMMPTIGHIQIASVPSRHEPDGEELNYPFLFAELDRLGYAGFVGAEYR
PRGATLDGLGWFAPFAGARM

Sequences:

>Translated_260_residues
MPRFAANLSLMFNEHAFLDRFDAAAAAGFTAVEFLFPYDHRPDDIAERLRRNNLMQALFNLPPGDWAGGEKGFAARPDKF
EDLQQSLHTALPYVLATGVRRVHLMAGLADRHDGAAALAFRRSLAVAAHFFAPHGIDVLIEPLNQRDVPGYFLDDFGFAH
DLIRELQIPNLMLQFDVYHCQILHGDVVMRLREMMPTIGHIQIASVPSRHEPDGEELNYPFLFAELDRLGYAGFVGAEYR
PRGATLDGLGWFAPFAGARM
>Mature_259_residues
PRFAANLSLMFNEHAFLDRFDAAAAAGFTAVEFLFPYDHRPDDIAERLRRNNLMQALFNLPPGDWAGGEKGFAARPDKFE
DLQQSLHTALPYVLATGVRRVHLMAGLADRHDGAAALAFRRSLAVAAHFFAPHGIDVLIEPLNQRDVPGYFLDDFGFAHD
LIRELQIPNLMLQFDVYHCQILHGDVVMRLREMMPTIGHIQIASVPSRHEPDGEELNYPFLFAELDRLGYAGFVGAEYRP
RGATLDGLGWFAPFAGARM

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=41.6030534351145, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=41.1522633744856, Blast_Score=157, Evalue=7e-39,
Organism=Escherichia coli, GI1789095, Length=254, Percent_Identity=42.9133858267717, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786718, Length=257, Percent_Identity=37.7431906614786, Blast_Score=190, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=36.25, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17530883, Length=258, Percent_Identity=32.1705426356589, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 29149; Mature: 29017

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSLMFNEHAFLDRFDAAAAAGFTAVEFLFPYDHRPDDIAERLRRNNLMQALFN
CCCHHCCEEEEECCHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWAGGEKGFAARPDKFEDLQQSLHTALPYVLATGVRRVHLMAGLADRHDGAAALAF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RRSLAVAAHFFAPHGIDVLIEPLNQRDVPGYFLDDFGFAHDLIRELQIPNLMLQFDVYHC
HHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEE
QILHGDVVMRLREMMPTIGHIQIASVPSRHEPDGEELNYPFLFAELDRLGYAGFVGAEYR
EEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PRGATLDGLGWFAPFAGARM
CCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
PRFAANLSLMFNEHAFLDRFDAAAAAGFTAVEFLFPYDHRPDDIAERLRRNNLMQALFN
CCHHCCEEEEECCHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHC
LPPGDWAGGEKGFAARPDKFEDLQQSLHTALPYVLATGVRRVHLMAGLADRHDGAAALAF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RRSLAVAAHFFAPHGIDVLIEPLNQRDVPGYFLDDFGFAHDLIRELQIPNLMLQFDVYHC
HHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEE
QILHGDVVMRLREMMPTIGHIQIASVPSRHEPDGEELNYPFLFAELDRLGYAGFVGAEYR
EEEHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
PRGATLDGLGWFAPFAGARM
CCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]