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The map label for this gene is mdtA [H]

Identifier: 86750718

GI number: 86750718

Start: 4140591

End: 4141793

Strand: Reverse

Name: mdtA [H]

Synonym: RPB_3608

Alternate gene names: 86750718

Gene position: 4141793-4140591 (Counterclockwise)

Preceding gene: 86750719

Following gene: 86750715

Centisome position: 77.68

GC content: 67.91

Gene sequence:

>1203_bases
ATGTCCACTGACGCCCCGCCGCGCAAATCCCGTCGCGGGCTCGGCATCGCCGGCATCCTGCTCGCCTGCGGTGCGGTCGC
CGTCGTCGTCACCGGGATCAGCGCACGCGAGAAGAGCAGCGCGGACCTGCGCCACTGGACCGACGAGCAGGCGATCTCCA
GCGTCGCGGTGACCCGGCCGGACGGTAAGGTGCTGACCAATACGCTCGATCTGCCGGGCCGGCTCGAGGCCTATTCCCGC
GCGCCGATCTACGCCCGCGTCTCCGGCTATGTGAAGAGCTGGAGCGCCGACATCGGCGCTCGGGTCAAGGCCGGGCAGGT
GATCGCCGAGGTCGAGGCGCCCGATCTCGATCAGCAATTGCTGCAGGCGCGCGCCGATCTCGCCAGCCAGCAGGCCAGCG
CGCGATTGTCCGAGGCGACGCTGAACCGCCGCAAGACGCTGCTGGCGTCGAACTTCGTCTCGGCGCAGGAAATCGACGAG
CGCAGCGCGGACCTCGCCAACAAGAAGGCCGCGGTGAATTCCGGCCAGGCCAATGTCGAACGGCTGGAAGCACTGGCCGG
CTACAAGAAGATCACCGCGCCGTTCGACGGCGTCGTCACCGAGCGCAACACCGACGTCGGCGCGCTGATCAGCGCCGGCT
CCAGCGCCGGACCCGCGATGTTCGTGGTGTCCGACATCGCGAAGCTGCGCGTCTACGTCAACGTGCCGCAGACTTATGTG
CCGATGATCAAGATCGGCGCCAAGGCGGTGATCACGCTGCCGGAATATCCGAACCGCAGCTTCCCGGCGACGGTCGAGGC
CTCGTCGCAGGCGGTCGACGTGTCCTCGGGCACCACGCGGATGCAACTTGCCCTGGACAACGCCAAGGGCGAGTTGATGC
CGGGCGGCTACGCCAATGTGAAGCTCAGCCTGGTGCGCGACGAGGTGTCGCTCTACATCCCGGCCAGCGCGCTGATGTTC
AACCGCAGCGGGCTGCGCGTCGCGGTCGTCGGCCCCGACGATCGCGTGCAGCTCAAGACCGTGACGATCGCTCGCGATCT
CGGCCGCGAAATCGAACTCGCCTCCGGCCTCTCACCCGATGACCGCATCATCGTCGCGCCGCCCGACGGCATCGCCGACG
GCGAGAAAGTCCGCGTTGTCGGCAATGATGCAGGCAAGGCCGGCAAGCCGACCGCGTCGGAGAAGCAGGACGTGAAGGGG
TAG

Upstream 100 bases:

>100_bases
TTTGCTACCATCGCGACGCTGATGTTCGTGCCGGTGGTGTTCAGCATGGTCCACAAGAAACAGCCGGCGCAGGACGAAGC
CCCGGTCGCGGAGATGTCGC

Downstream 100 bases:

>100_bases
TTCTCCGTCATTGCGAGGAGCCGTAGGCGACGAAGCAATCCAGCAGCTCCGTGCACGGCGCCGTTGGATTGCTTCGCTTC
GCTCGCAATGACGGAACGCA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSTDAPPRKSRRGLGIAGILLACGAVAVVVTGISAREKSSADLRHWTDEQAISSVAVTRPDGKVLTNTLDLPGRLEAYSR
APIYARVSGYVKSWSADIGARVKAGQVIAEVEAPDLDQQLLQARADLASQQASARLSEATLNRRKTLLASNFVSAQEIDE
RSADLANKKAAVNSGQANVERLEALAGYKKITAPFDGVVTERNTDVGALISAGSSAGPAMFVVSDIAKLRVYVNVPQTYV
PMIKIGAKAVITLPEYPNRSFPATVEASSQAVDVSSGTTRMQLALDNAKGELMPGGYANVKLSLVRDEVSLYIPASALMF
NRSGLRVAVVGPDDRVQLKTVTIARDLGREIELASGLSPDDRIIVAPPDGIADGEKVRVVGNDAGKAGKPTASEKQDVKG

Sequences:

>Translated_400_residues
MSTDAPPRKSRRGLGIAGILLACGAVAVVVTGISAREKSSADLRHWTDEQAISSVAVTRPDGKVLTNTLDLPGRLEAYSR
APIYARVSGYVKSWSADIGARVKAGQVIAEVEAPDLDQQLLQARADLASQQASARLSEATLNRRKTLLASNFVSAQEIDE
RSADLANKKAAVNSGQANVERLEALAGYKKITAPFDGVVTERNTDVGALISAGSSAGPAMFVVSDIAKLRVYVNVPQTYV
PMIKIGAKAVITLPEYPNRSFPATVEASSQAVDVSSGTTRMQLALDNAKGELMPGGYANVKLSLVRDEVSLYIPASALMF
NRSGLRVAVVGPDDRVQLKTVTIARDLGREIELASGLSPDDRIIVAPPDGIADGEKVRVVGNDAGKAGKPTASEKQDVKG
>Mature_399_residues
STDAPPRKSRRGLGIAGILLACGAVAVVVTGISAREKSSADLRHWTDEQAISSVAVTRPDGKVLTNTLDLPGRLEAYSRA
PIYARVSGYVKSWSADIGARVKAGQVIAEVEAPDLDQQLLQARADLASQQASARLSEATLNRRKTLLASNFVSAQEIDER
SADLANKKAAVNSGQANVERLEALAGYKKITAPFDGVVTERNTDVGALISAGSSAGPAMFVVSDIAKLRVYVNVPQTYVP
MIKIGAKAVITLPEYPNRSFPATVEASSQAVDVSSGTTRMQLALDNAKGELMPGGYANVKLSLVRDEVSLYIPASALMFN
RSGLRVAVVGPDDRVQLKTVTIARDLGREIELASGLSPDDRIIVAPPDGIADGEKVRVVGNDAGKAGKPTASEKQDVKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=314, Percent_Identity=25.4777070063694, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789929, Length=386, Percent_Identity=26.9430051813472, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786668, Length=385, Percent_Identity=25.4545454545455, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789665, Length=324, Percent_Identity=25, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081796, Length=315, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42158; Mature: 42027

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDAPPRKSRRGLGIAGILLACGAVAVVVTGISAREKSSADLRHWTDEQAISSVAVTRP
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHEEEECC
DGKVLTNTLDLPGRLEAYSRAPIYARVSGYVKSWSADIGARVKAGQVIAEVEAPDLDQQL
CCCEEEEECCCCCCHHHHCCCCEEEEHHHHHHHHCCCCCCEEECCEEEEECCCCCHHHHH
LQARADLASQQASARLSEATLNRRKTLLASNFVSAQEIDERSADLANKKAAVNSGQANVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RLEALAGYKKITAPFDGVVTERNTDVGALISAGSSAGPAMFVVSDIAKLRVYVNVPQTYV
HHHHHHCCCEECCCCCCEEECCCCCHHHEEECCCCCCCEEHEEECCEEEEEEEECCCHHH
PMIKIGAKAVITLPEYPNRSFPATVEASSQAVDVSSGTTRMQLALDNAKGELMPGGYANV
HHEEECCEEEEECCCCCCCCCCEEEECCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCE
KLSLVRDEVSLYIPASALMFNRSGLRVAVVGPDDRVQLKTVTIARDLGREIELASGLSPD
EEEEEEECEEEEECHHHEEECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEHHCCCCCC
DRIIVAPPDGIADGEKVRVVGNDAGKAGKPTASEKQDVKG
CEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
STDAPPRKSRRGLGIAGILLACGAVAVVVTGISAREKSSADLRHWTDEQAISSVAVTRP
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHEEEECC
DGKVLTNTLDLPGRLEAYSRAPIYARVSGYVKSWSADIGARVKAGQVIAEVEAPDLDQQL
CCCEEEEECCCCCCHHHHCCCCEEEEHHHHHHHHCCCCCCEEECCEEEEECCCCCHHHHH
LQARADLASQQASARLSEATLNRRKTLLASNFVSAQEIDERSADLANKKAAVNSGQANVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
RLEALAGYKKITAPFDGVVTERNTDVGALISAGSSAGPAMFVVSDIAKLRVYVNVPQTYV
HHHHHHCCCEECCCCCCEEECCCCCHHHEEECCCCCCCEEHEEECCEEEEEEEECCCHHH
PMIKIGAKAVITLPEYPNRSFPATVEASSQAVDVSSGTTRMQLALDNAKGELMPGGYANV
HHEEECCEEEEECCCCCCCCCCEEEECCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCE
KLSLVRDEVSLYIPASALMFNRSGLRVAVVGPDDRVQLKTVTIARDLGREIELASGLSPD
EEEEEEECEEEEECHHHEEECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEHHCCCCCC
DRIIVAPPDGIADGEKVRVVGNDAGKAGKPTASEKQDVKG
CEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]