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The map label for this gene is cph2 [H]

Identifier: 86750684

GI number: 86750684

Start: 4097913

End: 4098698

Strand: Reverse

Name: cph2 [H]

Synonym: RPB_3574

Alternate gene names: 86750684

Gene position: 4098698-4097913 (Counterclockwise)

Preceding gene: 86750685

Following gene: 86750680

Centisome position: 76.87

GC content: 68.83

Gene sequence:

>786_bases
ATGACGAAGCAGATCGTCACGCATCGGGACGCGATCAACTATACCGCGGGGCGGATGGCGCTGGCGGGCGGGCTGACCGC
GCTGGTGACGCTGCTCTTCCTTCTCTCCGATCTCGGCGCCGACGCCAAGGCTCTGGTGCCGGTCGGCGAGGTGCAACATG
CATCCCTGATAGTCGCGGTCGGCGTATCGACCGTCCTGTCGGGGGCGCTGAGTTATCGCTCGGCGATCCTGATGCGGCAG
TTGACGCTGACCCGCGCGGAACTGGCGCGGATCTCGCGCACCGATCCCTTGACCGGGCTGCTCAACCGGCGCGGCTTCGA
CGACGCGGCCGCGCCCTTGCTGGCGCAGGCCGCGGCGGCGGGGCAGCGCGTGGTCGCGCTGATGTGCGACATCGACCGCT
TCAAGACGATCAACGACCGCTACGGGCACGACGCGGGGGATCGCGTACTCGCCCGGATCGGCACCATTCTGAGCGACTTC
GCCGAAGCCAATGGTGCGGTGATCGCCCGCCACGGCGGCGAGGAATTCGCCGGCCTGATGGTCGGAGTCAGCGACGAGGA
GGCCACCCGCTACGCGCAGGCCCTGTGCAAGCTGTGCTCGACCGACGTGGCAGGAAACGACGTCGCGGTGCCGGTGACCA
TGAGCTTCGGCCTCGCCACGCATCTGCCGGGCGGCGATCTCGCCGCGCTGATGCGCCGGGCGGATCAGGCGCTGTATCGC
GCCAAGGATCTCGGCCGCAATTGCGTCGTGCAGATCGACGAGCTGGAAGCCGTGGCGGCCTGCTAG

Upstream 100 bases:

>100_bases
GAGTGCGTGCGCGCGGAATTGACCGCGCTTTCTTGACAGGGCGGGGACGGGGACCGGAGCGCGTGCGCGTGATCGGCGGC
GTCTCTCTTGTGGTGAAGAC

Downstream 100 bases:

>100_bases
CGCAGCTCTGAATTTGATGGAACCATCGCCGTCATCCTGAGGTGCCCGCTGGGCCGCGCCATGCGCGGCCCAGCGGGCCT
CGAAGGATGAGCCGCAAGCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTKQIVTHRDAINYTAGRMALAGGLTALVTLLFLLSDLGADAKALVPVGEVQHASLIVAVGVSTVLSGALSYRSAILMRQ
LTLTRAELARISRTDPLTGLLNRRGFDDAAAPLLAQAAAAGQRVVALMCDIDRFKTINDRYGHDAGDRVLARIGTILSDF
AEANGAVIARHGGEEFAGLMVGVSDEEATRYAQALCKLCSTDVAGNDVAVPVTMSFGLATHLPGGDLAALMRRADQALYR
AKDLGRNCVVQIDELEAVAAC

Sequences:

>Translated_261_residues
MTKQIVTHRDAINYTAGRMALAGGLTALVTLLFLLSDLGADAKALVPVGEVQHASLIVAVGVSTVLSGALSYRSAILMRQ
LTLTRAELARISRTDPLTGLLNRRGFDDAAAPLLAQAAAAGQRVVALMCDIDRFKTINDRYGHDAGDRVLARIGTILSDF
AEANGAVIARHGGEEFAGLMVGVSDEEATRYAQALCKLCSTDVAGNDVAVPVTMSFGLATHLPGGDLAALMRRADQALYR
AKDLGRNCVVQIDELEAVAAC
>Mature_260_residues
TKQIVTHRDAINYTAGRMALAGGLTALVTLLFLLSDLGADAKALVPVGEVQHASLIVAVGVSTVLSGALSYRSAILMRQL
TLTRAELARISRTDPLTGLLNRRGFDDAAAPLLAQAAAAGQRVVALMCDIDRFKTINDRYGHDAGDRVLARIGTILSDFA
EANGAVIARHGGEEFAGLMVGVSDEEATRYAQALCKLCSTDVAGNDVAVPVTMSFGLATHLPGGDLAALMRRADQALYRA
KDLGRNCVVQIDELEAVAAC

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=37.3493975903614, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787816, Length=193, Percent_Identity=32.6424870466321, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=175, Percent_Identity=33.7142857142857, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=35.1515151515151, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=34.9693251533742, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081977, Length=112, Percent_Identity=40.1785714285714, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=178, Percent_Identity=33.7078651685393, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=29.5180722891566, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788381, Length=197, Percent_Identity=30.4568527918782, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787056, Length=182, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=32.0754716981132, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 27434; Mature: 27303

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQIVTHRDAINYTAGRMALAGGLTALVTLLFLLSDLGADAKALVPVGEVQHASLIVAV
CCCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH
GVSTVLSGALSYRSAILMRQLTLTRAELARISRTDPLTGLLNRRGFDDAAAPLLAQAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHC
GQRVVALMCDIDRFKTINDRYGHDAGDRVLARIGTILSDFAEANGAVIARHGGEEFAGLM
CHHHHHHHHCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHEE
VGVSDEEATRYAQALCKLCSTDVAGNDVAVPVTMSFGLATHLPGGDLAALMRRADQALYR
EECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHCCCCHHHHHHHHHHHHHHHH
AKDLGRNCVVQIDELEAVAAC
HHHCCCCEEEEEHHHHHHHCC
>Mature Secondary Structure 
TKQIVTHRDAINYTAGRMALAGGLTALVTLLFLLSDLGADAKALVPVGEVQHASLIVAV
CCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH
GVSTVLSGALSYRSAILMRQLTLTRAELARISRTDPLTGLLNRRGFDDAAAPLLAQAAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHC
GQRVVALMCDIDRFKTINDRYGHDAGDRVLARIGTILSDFAEANGAVIARHGGEEFAGLM
CHHHHHHHHCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHEE
VGVSDEEATRYAQALCKLCSTDVAGNDVAVPVTMSFGLATHLPGGDLAALMRRADQALYR
EECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHCCCCHHHHHHHHHHHHHHHH
AKDLGRNCVVQIDELEAVAAC
HHHCCCCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]