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The map label for this gene is rpiA

Identifier: 86750497

GI number: 86750497

Start: 3870885

End: 3871583

Strand: Reverse

Name: rpiA

Synonym: RPB_3386

Alternate gene names: 86750497

Gene position: 3871583-3870885 (Counterclockwise)

Preceding gene: 86750503

Following gene: 86750496

Centisome position: 72.62

GC content: 66.95

Gene sequence:

>699_bases
ATGAACAAGGAAGATCTGAAGCGGCAGGCCGCCGCGCGCGCGCTGGACGAGGTTCGCGACGGGATGAAGATCGGTCTCGG
CACCGGCTCGACCGCCAAGCATTTCGTCGAGCTGCTGGGCGAAAAGGTCCGTGCCGGTCTCGACGTCATCGGCGTGCCGA
CCTCCGAGGTGACCCGGGCCGACGCCGAGCGCTGCGGCATCCGGCTGACCACGCTCGACGAGATCGACCGGCTCGACCTG
ACGGTCGATGGCGCCGATGAGATCGATCCGCGGCTCGAACTGATCAAGGGCGGCGGCGGCGCGCTGCTGCGCGAGAAGAT
CGTCGCCGCCGCATCCGATCGCATGATCGTGATCGCCGACGAAACCAAATGGGTCGACTGCCTCGGCCATTTTCCGCTGC
CGGTCGAAGTGATCCCGTTCGGGCTGGCCGCGACCCGGCGCGCGATCGAACAGGCCTGCGCCGAGGTCGGCGCATCCGGT
CGATTGCAGCTTCGCGAAGGCAAGGACGGCCATGCTTTCGTCACCGATGGTGGCCACTGGATCATCGACGCCCACCTCGG
GCGGATACCGGATGCGCCTCGCCTGGCCCAGCTGTTGTCGGCGATTCCGGGCGTAGTCGAGCATGGGTTGTTCATCGGGA
TCGCCAGCACGGTCGTGCTCGCGGGGACCGACGGAATTCGAACTGTCGAACGGGCGTAG

Upstream 100 bases:

>100_bases
GGCTGGCGACGGAATCCACCCTGTTGTTATGCCGCAAACGTCGCTAGATATGCCGCGCTGCGCCGGGGACGGTCGGTGGG
GAGCAGGGGTCGGTATTGCA

Downstream 100 bases:

>100_bases
CGCCACATCCTGGAGAATCGGAAATGAAGTATCTGTCGAAAGCCCTGCCGGCCGTCGTGCTGGCGCTCGGCCTGGCGTTG
TCGGTCGGCCATGCGCAGGC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKEDLKRQAAARALDEVRDGMKIGLGTGSTAKHFVELLGEKVRAGLDVIGVPTSEVTRADAERCGIRLTTLDEIDRLDL
TVDGADEIDPRLELIKGGGGALLREKIVAAASDRMIVIADETKWVDCLGHFPLPVEVIPFGLAATRRAIEQACAEVGASG
RLQLREGKDGHAFVTDGGHWIIDAHLGRIPDAPRLAQLLSAIPGVVEHGLFIGIASTVVLAGTDGIRTVERA

Sequences:

>Translated_232_residues
MNKEDLKRQAAARALDEVRDGMKIGLGTGSTAKHFVELLGEKVRAGLDVIGVPTSEVTRADAERCGIRLTTLDEIDRLDL
TVDGADEIDPRLELIKGGGGALLREKIVAAASDRMIVIADETKWVDCLGHFPLPVEVIPFGLAATRRAIEQACAEVGASG
RLQLREGKDGHAFVTDGGHWIIDAHLGRIPDAPRLAQLLSAIPGVVEHGLFIGIASTVVLAGTDGIRTVERA
>Mature_232_residues
MNKEDLKRQAAARALDEVRDGMKIGLGTGSTAKHFVELLGEKVRAGLDVIGVPTSEVTRADAERCGIRLTTLDEIDRLDL
TVDGADEIDPRLELIKGGGGALLREKIVAAASDRMIVIADETKWVDCLGHFPLPVEVIPFGLAATRRAIEQACAEVGASG
RLQLREGKDGHAFVTDGGHWIIDAHLGRIPDAPRLAQLLSAIPGVVEHGLFIGIASTVVLAGTDGIRTVERA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=231, Percent_Identity=38.5281385281385, Blast_Score=137, Evalue=8e-33,
Organism=Escherichia coli, GI1789280, Length=232, Percent_Identity=41.3793103448276, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17551758, Length=229, Percent_Identity=39.7379912663755, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324669, Length=238, Percent_Identity=34.8739495798319, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281364072, Length=221, Percent_Identity=34.3891402714932, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_RHOP2 (Q2IUM8)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486993.1
- ProteinModelPortal:   Q2IUM8
- SMR:   Q2IUM8
- STRING:   Q2IUM8
- GeneID:   3911188
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_3386
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- BioCyc:   RPAL316058:RPB_3386-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24676; Mature: 24676

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEDLKRQAAARALDEVRDGMKIGLGTGSTAKHFVELLGEKVRAGLDVIGVPTSEVTRA
CCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHH
DAERCGIRLTTLDEIDRLDLTVDGADEIDPRLELIKGGGGALLREKIVAAASDRMIVIAD
HHHHHCEEEEEHHCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEC
ETKWVDCLGHFPLPVEVIPFGLAATRRAIEQACAEVGASGRLQLREGKDGHAFVTDGGHW
CCCHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCE
IIDAHLGRIPDAPRLAQLLSAIPGVVEHGLFIGIASTVVLAGTDGIRTVERA
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCHHHCCC
>Mature Secondary Structure
MNKEDLKRQAAARALDEVRDGMKIGLGTGSTAKHFVELLGEKVRAGLDVIGVPTSEVTRA
CCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHH
DAERCGIRLTTLDEIDRLDLTVDGADEIDPRLELIKGGGGALLREKIVAAASDRMIVIAD
HHHHHCEEEEEHHCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEC
ETKWVDCLGHFPLPVEVIPFGLAATRRAIEQACAEVGASGRLQLREGKDGHAFVTDGGHW
CCCHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCE
IIDAHLGRIPDAPRLAQLLSAIPGVVEHGLFIGIASTVVLAGTDGIRTVERA
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA