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The map label for this gene is uxuR [H]

Identifier: 86750451

GI number: 86750451

Start: 3821164

End: 3821928

Strand: Reverse

Name: uxuR [H]

Synonym: RPB_3340

Alternate gene names: 86750451

Gene position: 3821928-3821164 (Counterclockwise)

Preceding gene: 86750452

Following gene: 86750450

Centisome position: 71.68

GC content: 69.02

Gene sequence:

>765_bases
ATGGCGACCCCGCTCAATTCCGAGACCACCCACACGGTCCGCAGGACGCTCGAATTCGTCCAGCACCATCGGCTGGCGAA
GGGCGACCGGCTGCCGTCGGAGCGGGAATTGTCGGAGCGGTTCGGGGTGGCGCGCAGTTCGGTGCGCGAGGCGCTGGCGG
TGCTGGACGCGATGCGGATCACCGAGCGCAAGCCGAAATCGGGCATCTTCCTGCGCAACGCGGTCGAGGACGGCGGGCTC
GATGCGCTGGTGCTGCAGGCCGATCTCGGGCTGGCGTTCGATCCGCAGGTGACGCGCGACGTCACCGAGGCGCGGATCAT
CTGCGAGGAGCAGGCGCTGCGGATTGCCTGCCGCAGGCGCACTGACGCTGATCTGGCGAAGCTGCACCGATTGCTCGACG
GCTATGCCGGGCTGGTCGACGCCGACCGCAATCCCGCCGATGCCGACGTCGATTTTCACCTCGCGCTCGTCGCCGCGAGT
CAGAACCGGATTCTGGTGCGCACGCTGACGCCGCTGATGCTGATGAGCACGAATTGGCGGCGGCGCTATTTCGATTCCGC
CGCGATCCGCCGTCGTTCGCTCGACGATCACCGCGCCTTCGTGGCCGCGATCGAAGCGCGCGACGAAGCCGCCACCTCGG
CGCTGGTGCAGCGCCACGTGCAGACCGCCGCGGCCGACGTGCGCGCTCTGGCGGAGCAGGGCGGCGCGACCGCGACCGAC
ACGCCATCCAAATCAGACACGCGCGCATCCGACGCGCCGACATAA

Upstream 100 bases:

>100_bases
GGGGCGAGGGGGCGCGCCGTGCGCGGGGCGAGGCCGGACGGTTCAATCCGCCGCAGCCTCGGCGCCTTGATCTGGTCAGA
CCAGATTGGTAGGGTCAGTT

Downstream 100 bases:

>100_bases
CCCCGGTCAACGGGAGAACTTCGCGCGGCCAACAGCCGCTTCGGGGAAACGCAAAAAGAAGGATCAAAAATGCGTATGAC
GACGACTTCCGTGGCCGCGT

Product: regulatory protein GntR, HTH:GntR-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MATPLNSETTHTVRRTLEFVQHHRLAKGDRLPSERELSERFGVARSSVREALAVLDAMRITERKPKSGIFLRNAVEDGGL
DALVLQADLGLAFDPQVTRDVTEARIICEEQALRIACRRRTDADLAKLHRLLDGYAGLVDADRNPADADVDFHLALVAAS
QNRILVRTLTPLMLMSTNWRRRYFDSAAIRRRSLDDHRAFVAAIEARDEAATSALVQRHVQTAAADVRALAEQGGATATD
TPSKSDTRASDAPT

Sequences:

>Translated_254_residues
MATPLNSETTHTVRRTLEFVQHHRLAKGDRLPSERELSERFGVARSSVREALAVLDAMRITERKPKSGIFLRNAVEDGGL
DALVLQADLGLAFDPQVTRDVTEARIICEEQALRIACRRRTDADLAKLHRLLDGYAGLVDADRNPADADVDFHLALVAAS
QNRILVRTLTPLMLMSTNWRRRYFDSAAIRRRSLDDHRAFVAAIEARDEAATSALVQRHVQTAAADVRALAEQGGATATD
TPSKSDTRASDAPT
>Mature_253_residues
ATPLNSETTHTVRRTLEFVQHHRLAKGDRLPSERELSERFGVARSSVREALAVLDAMRITERKPKSGIFLRNAVEDGGLD
ALVLQADLGLAFDPQVTRDVTEARIICEEQALRIACRRRTDADLAKLHRLLDGYAGLVDADRNPADADVDFHLALVAASQ
NRILVRTLTPLMLMSTNWRRRYFDSAAIRRRSLDDHRAFVAAIEARDEAATSALVQRHVQTAAADVRALAEQGGATATDT
PSKSDTRASDAPT

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790032, Length=188, Percent_Identity=30.8510638297872, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786303, Length=220, Percent_Identity=30, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790780, Length=206, Percent_Identity=26.2135922330097, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28031; Mature: 27900

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLNSETTHTVRRTLEFVQHHRLAKGDRLPSERELSERFGVARSSVREALAVLDAMRI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERKPKSGIFLRNAVEDGGLDALVLQADLGLAFDPQVTRDVTEARIICEEQALRIACRRR
HCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TDADLAKLHRLLDGYAGLVDADRNPADADVDFHLALVAASQNRILVRTLTPLMLMSTNWR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHCCCHH
RRYFDSAAIRRRSLDDHRAFVAAIEARDEAATSALVQRHVQTAAADVRALAEQGGATATD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TPSKSDTRASDAPT
CCCCCCCCCCCCCC
>Mature Secondary Structure 
ATPLNSETTHTVRRTLEFVQHHRLAKGDRLPSERELSERFGVARSSVREALAVLDAMRI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERKPKSGIFLRNAVEDGGLDALVLQADLGLAFDPQVTRDVTEARIICEEQALRIACRRR
HCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TDADLAKLHRLLDGYAGLVDADRNPADADVDFHLALVAASQNRILVRTLTPLMLMSTNWR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHCCCHH
RRYFDSAAIRRRSLDDHRAFVAAIEARDEAATSALVQRHVQTAAADVRALAEQGGATATD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TPSKSDTRASDAPT
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]