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The map label for this gene is cph2 [H]

Identifier: 86750359

GI number: 86750359

Start: 3711024

End: 3712286

Strand: Reverse

Name: cph2 [H]

Synonym: RPB_3248

Alternate gene names: 86750359

Gene position: 3712286-3711024 (Counterclockwise)

Preceding gene: 86750360

Following gene: 86750358

Centisome position: 69.63

GC content: 63.82

Gene sequence:

>1263_bases
ATGATGCGGCGGGCTGCAATGATGATCGATTATCTCCACAGCCGCGTAGCCGCCGCGCGCCGCGTGATGTCGTCCACCGC
CGGATTGATCGGATCCGACTACACGTCGGAAGAGCAGGCGTGGGAAATGCTGGAGGGGCTGTTCAGCCCGTTCGCCCATG
CCCTGACGGCGACGGCGATCGCGATCACCGCGTGGTACAATTGGCATTCCCACAATTCGCTGGCGTCGTTTGCGGCGGTT
GCTGTCGTCGGGCCGACATTGTCGTTGCGGCTTCTTCTGGCGCAGCGCTTCCGCACGCGCGGACCCGACGCGCGGGTCTC
GAAATGGGTTCGCCTGTTCGCGATCATGAGCTTCGTCGCGGCGATTGGCTGGGGCTCCAGCCTGTCGATCCTCATCTTCA
CCACCGAGGGATTGCCGCTGTTCGCGGTTTTCGCGTTGATCTGCGCGCCGGTGCAGGGCGCCAGCGCGCGCGCTTATGCG
ATGCCGTCGGTCGTGATCCTCCATATCAGCATCGTGTTGGGCCTGGTCGGCATCGCGGCGACGGTGTTCGGGATCGCAAT
CGCCATCCCGTTCTGCCTTCTCTATTTGTGGTACCAGATCGGCTTCGTCATGGAGCTGGTCGCGCTGCGCCGGAAAATGC
TGAAAGCCGACCACGACCGGCGTCAGTTGCTGACTCAGGTGACGCGCTACAATGCGGATCTCGCATCGCTGAACACCCAG
CTTTCGGCGTTCGCGCTCACCGATGGTCTGACCGGCGTCGGCAACCGGCGGGATTTCGACGACAAGCTGCAGCGTTTCCT
GACGGGCCAGACAAACGCGACGACACCACTGGCCCTTCTTCTGATCGACGTCGATCGCTTCAAACGGCTCAACGACACTT
ACGGGCATTTGGTCGGCGACCAATGCCTGAAACTGTTGGCGACCGCGATCAGATGCGTCGTGAGCAGGAGCGGAGACGTC
GTCGCACGCTATGGCGGCGAGGAGTTCGCGGCGATCCTGCCGGCGACGGACGCGGCAACTGCCCTGGCGATCGCGGAACG
TATCCGGCGCGCGATTGAAACCATGGACCTCGCCGGCCTGCCGAAATTGGACGAGCGGCCGACGGTGAGCATCGGCGTCG
GCATCGCCGCTTCCGGAACGACGATGCTGCCGCACGCGTTGATCGAAATCGCCGACGCTGCTCTGTATGCGGCCAAGCAG
AGCGGTCGCAATTGTGTCCGACATGGCGCCGCGACTCGCCAGCCGCTGCGCCACATCGCCTAG

Upstream 100 bases:

>100_bases
CCTTAACGTCCGATTCAGAATAGCGGCAACGGGTAAAATAGGGTTCTGCCGCCGTTCAGACATTCCCGCCATTGTTTCGG
TCGCACGAGCGAATTCGGAA

Downstream 100 bases:

>100_bases
CGTCGCTTCGGCCAGGCCGCCTGCCGATTGACAACGAAATGCGGGAGTTCGTAACTGAGCCGACACGAGCACAGGATGAC
AGAATGGCCGACGGATTGCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MMRRAAMMIDYLHSRVAAARRVMSSTAGLIGSDYTSEEQAWEMLEGLFSPFAHALTATAIAITAWYNWHSHNSLASFAAV
AVVGPTLSLRLLLAQRFRTRGPDARVSKWVRLFAIMSFVAAIGWGSSLSILIFTTEGLPLFAVFALICAPVQGASARAYA
MPSVVILHISIVLGLVGIAATVFGIAIAIPFCLLYLWYQIGFVMELVALRRKMLKADHDRRQLLTQVTRYNADLASLNTQ
LSAFALTDGLTGVGNRRDFDDKLQRFLTGQTNATTPLALLLIDVDRFKRLNDTYGHLVGDQCLKLLATAIRCVVSRSGDV
VARYGGEEFAAILPATDAATALAIAERIRRAIETMDLAGLPKLDERPTVSIGVGIAASGTTMLPHALIEIADAALYAAKQ
SGRNCVRHGAATRQPLRHIA

Sequences:

>Translated_420_residues
MMRRAAMMIDYLHSRVAAARRVMSSTAGLIGSDYTSEEQAWEMLEGLFSPFAHALTATAIAITAWYNWHSHNSLASFAAV
AVVGPTLSLRLLLAQRFRTRGPDARVSKWVRLFAIMSFVAAIGWGSSLSILIFTTEGLPLFAVFALICAPVQGASARAYA
MPSVVILHISIVLGLVGIAATVFGIAIAIPFCLLYLWYQIGFVMELVALRRKMLKADHDRRQLLTQVTRYNADLASLNTQ
LSAFALTDGLTGVGNRRDFDDKLQRFLTGQTNATTPLALLLIDVDRFKRLNDTYGHLVGDQCLKLLATAIRCVVSRSGDV
VARYGGEEFAAILPATDAATALAIAERIRRAIETMDLAGLPKLDERPTVSIGVGIAASGTTMLPHALIEIADAALYAAKQ
SGRNCVRHGAATRQPLRHIA
>Mature_420_residues
MMRRAAMMIDYLHSRVAAARRVMSSTAGLIGSDYTSEEQAWEMLEGLFSPFAHALTATAIAITAWYNWHSHNSLASFAAV
AVVGPTLSLRLLLAQRFRTRGPDARVSKWVRLFAIMSFVAAIGWGSSLSILIFTTEGLPLFAVFALICAPVQGASARAYA
MPSVVILHISIVLGLVGIAATVFGIAIAIPFCLLYLWYQIGFVMELVALRRKMLKADHDRRQLLTQVTRYNADLASLNTQ
LSAFALTDGLTGVGNRRDFDDKLQRFLTGQTNATTPLALLLIDVDRFKRLNDTYGHLVGDQCLKLLATAIRCVVSRSGDV
VARYGGEEFAAILPATDAATALAIAERIRRAIETMDLAGLPKLDERPTVSIGVGIAASGTTMLPHALIEIADAALYAAKQ
SGRNCVRHGAATRQPLRHIA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=175, Percent_Identity=41.1428571428571, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786584, Length=278, Percent_Identity=28.7769784172662, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=37.2670807453416, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI145693134, Length=186, Percent_Identity=36.5591397849462, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787802, Length=184, Percent_Identity=36.4130434782609, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788381, Length=167, Percent_Identity=35.3293413173653, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=32.2222222222222, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=32.5301204819277, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=35.031847133758, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=167, Percent_Identity=29.940119760479, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787056, Length=173, Percent_Identity=29.4797687861272, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788956, Length=190, Percent_Identity=29.4736842105263, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=31.547619047619, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789650, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 45527; Mature: 45527

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRRAAMMIDYLHSRVAAARRVMSSTAGLIGSDYTSEEQAWEMLEGLFSPFAHALTATAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AITAWYNWHSHNSLASFAAVAVVGPTLSLRLLLAQRFRTRGPDARVSKWVRLFAIMSFVA
HHHHEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIGWGSSLSILIFTTEGLPLFAVFALICAPVQGASARAYAMPSVVILHISIVLGLVGIAA
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TVFGIAIAIPFCLLYLWYQIGFVMELVALRRKMLKADHDRRQLLTQVTRYNADLASLNTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
LSAFALTDGLTGVGNRRDFDDKLQRFLTGQTNATTPLALLLIDVDRFKRLNDTYGHLVGD
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHH
QCLKLLATAIRCVVSRSGDVVARYGGEEFAAILPATDAATALAIAERIRRAIETMDLAGL
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
PKLDERPTVSIGVGIAASGTTMLPHALIEIADAALYAAKQSGRNCVRHGAATRQPLRHIA
CCCCCCCCEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MMRRAAMMIDYLHSRVAAARRVMSSTAGLIGSDYTSEEQAWEMLEGLFSPFAHALTATAI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AITAWYNWHSHNSLASFAAVAVVGPTLSLRLLLAQRFRTRGPDARVSKWVRLFAIMSFVA
HHHHEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIGWGSSLSILIFTTEGLPLFAVFALICAPVQGASARAYAMPSVVILHISIVLGLVGIAA
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TVFGIAIAIPFCLLYLWYQIGFVMELVALRRKMLKADHDRRQLLTQVTRYNADLASLNTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHH
LSAFALTDGLTGVGNRRDFDDKLQRFLTGQTNATTPLALLLIDVDRFKRLNDTYGHLVGD
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHH
QCLKLLATAIRCVVSRSGDVVARYGGEEFAAILPATDAATALAIAERIRRAIETMDLAGL
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
PKLDERPTVSIGVGIAASGTTMLPHALIEIADAALYAAKQSGRNCVRHGAATRQPLRHIA
CCCCCCCCEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]