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The map label for this gene is gpt

Identifier: 86750324

GI number: 86750324

Start: 3676086

End: 3676604

Strand: Reverse

Name: gpt

Synonym: RPB_3213

Alternate gene names: 86750324

Gene position: 3676604-3676086 (Counterclockwise)

Preceding gene: 86750325

Following gene: 86750323

Centisome position: 68.96

GC content: 68.21

Gene sequence:

>519_bases
ATGGGCAGCGACGCAGATGCCGACCTAGGGGAGCGGCGGCCGTTTCCGGTGTCGTGGGATCAGTTCCACCGCGACTGCCG
GGCGCTGACCTGGCGGCTCAACGAGGTCGGGCCGTTTGCCGCGGTGATCGCCATCACCCGCGGCGGGCTGGTGCCGGCGG
CGATCGTCGCGCGCGAACTCGGCCTGCGGGTGATCGACACCATCTGCGTAGCGAGCTACGCCCACGACAAGCAGGGCGAT
CTGCAGGTGCTGAAAGGCGTCTCCGAACAGACCGCGGCGCTGGGCCACGGCACCGGCAAGGGGCTGTTGATCGTCGACGA
TCTGGTCGACACCGGCAAGACCGGCCGCATGGTCCGCGACCTGTTGCCCGACGCGCATTTCGCCACCGTCTACGCCAAGC
CGATGGGCAAGCCGCTGGTCGACACCTTCATCACCGAGGTCTCGCAGGACACCTGGATCTTCTTCCCGTGGGACACCGGC
CTGAGCTTCCAGCCGCCACTGAAGGACGGCGCGGCCTAA

Upstream 100 bases:

>100_bases
GGCAAGTCTGCCAGCTCAGCGGCGAATTGCTGCAGGACGAGCGCCTGGTGGCGACCGGCACCGCGACCGCGGTGATCCGC
AGAATGGGGACCGAGACCGC

Downstream 100 bases:

>100_bases
CCTCTCCCCGCGCGCGGGGAGAGGTCGGATTGCGCAGCAATCCGGGTGAGGGGGCGTCGCGACGAGTCTGAGCCTTTCGC
ATTTCGGGTGGCAAACGCCG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MGSDADADLGERRPFPVSWDQFHRDCRALTWRLNEVGPFAAVIAITRGGLVPAAIVARELGLRVIDTICVASYAHDKQGD
LQVLKGVSEQTAALGHGTGKGLLIVDDLVDTGKTGRMVRDLLPDAHFATVYAKPMGKPLVDTFITEVSQDTWIFFPWDTG
LSFQPPLKDGAA

Sequences:

>Translated_172_residues
MGSDADADLGERRPFPVSWDQFHRDCRALTWRLNEVGPFAAVIAITRGGLVPAAIVARELGLRVIDTICVASYAHDKQGD
LQVLKGVSEQTAALGHGTGKGLLIVDDLVDTGKTGRMVRDLLPDAHFATVYAKPMGKPLVDTFITEVSQDTWIFFPWDTG
LSFQPPLKDGAA
>Mature_171_residues
GSDADADLGERRPFPVSWDQFHRDCRALTWRLNEVGPFAAVIAITRGGLVPAAIVARELGLRVIDTICVASYAHDKQGDL
QVLKGVSEQTAALGHGTGKGLLIVDDLVDTGKTGRMVRDLLPDAHFATVYAKPMGKPLVDTFITEVSQDTWIFFPWDTGL
SFQPPLKDGAA

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=153, Percent_Identity=46.4052287581699, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_RHOP2 (Q2IV51)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486820.1
- ProteinModelPortal:   Q2IV51
- SMR:   Q2IV51
- STRING:   Q2IV51
- GeneID:   3911014
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_3213
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BioCyc:   RPAL316058:RPB_3213-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18631; Mature: 18500

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 110-110 BINDING 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSDADADLGERRPFPVSWDQFHRDCRALTWRLNEVGPFAAVIAITRGGLVPAAIVAREL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
GLRVIDTICVASYAHDKQGDLQVLKGVSEQTAALGHGTGKGLLIVDDLVDTGKTGRMVRD
HHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHH
LLPDAHFATVYAKPMGKPLVDTFITEVSQDTWIFFPWDTGLSFQPPLKDGAA
HCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GSDADADLGERRPFPVSWDQFHRDCRALTWRLNEVGPFAAVIAITRGGLVPAAIVAREL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHH
GLRVIDTICVASYAHDKQGDLQVLKGVSEQTAALGHGTGKGLLIVDDLVDTGKTGRMVRD
HHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHH
LLPDAHFATVYAKPMGKPLVDTFITEVSQDTWIFFPWDTGLSFQPPLKDGAA
HCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA