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The map label for this gene is cyaA [H]

Identifier: 86750264

GI number: 86750264

Start: 3607257

End: 3609536

Strand: Reverse

Name: cyaA [H]

Synonym: RPB_3153

Alternate gene names: 86750264

Gene position: 3609536-3607257 (Counterclockwise)

Preceding gene: 86750266

Following gene: 86750260

Centisome position: 67.7

GC content: 69.17

Gene sequence:

>2280_bases
GTGCGCCGGCTGAGCCGCGATGCGCATCCGTTTCTGACCCGCGCCGCGCCGGTCTGGGTCCGGTTGCGACGGCTGACGCG
TAGCAAGTCGGCGCGCGCGGTTGCAGCGGCGCTGCTGACGCTGATCGCGCTGACGGCGCTGCGCACTTACGATCCGCGGC
TGGTCCATGAAACCAAGGAACGCGCCTTCGACGCGTATCAGCGATTGTCACCGCGGCCGCACGCCGATCTTCCGGTGCGG
ATCGTCGATATCGACGAGGCGTCGCTCGCCGCCTATGGGCAGTGGCCGTGGCCGCGCACCCGGCTGGCGGCGCTGACCAA
ACGGCTGGGTGAACTCGGCGTCGGCGTCGTGGCCTACGACATCATCTTCTCGGAGCCCGACCGCACCACGCCGGGCCGCC
TCGCCAGCGAACTCGGCGATGCCGATCTGCCGGATCGCGATCTCACCGTCGCGCTGCTGAAGAGCCTGCCGGATCACGAT
CAGAGCTTGGCGCAGGCGATGCAGAAGACGCCGACCGTGCTCGGTTTCGCCGCCATCCAGCGTGCCAACGCGACACGGCC
GTCGGTGAAAGCGGGGCTCGCCGTCGTCGGCGTCCAACCCGCCTTCGTGCTGCCGCCGTTCCGCGGCGCCGTCTCCAATC
TGCCGGTGCTCGACGAGGCTGCGGCGGGAATCGGCGCGATCAATCTGTCGGCGCGCGACCGATCCGGCGTGGTTCGCCGG
CTGCCGATGCTGATGTCGGACGGCGCGCGGGTGTATCCGAGCCTGGCGATCGAGGCGCTGCGCGTCGCGCAGAACCAGAA
GGGCATCGTGGTGCGCGGCACCGGCGCCAGCGGCGAGGCCGACACCGGGCACGCCGCGCTGCTGGATATGCGGGTCGGCC
AGTTCAAGCTGCCGCTGACGCCCGACGGCGAGGCCTGGCTGTATTTCAACCGCGACCGCCGGGATCGATACGTTTCGGTG
AAGGACGTGCTCGACCCGGCCAAGGACGCCGAGATGCGCGACAAGCTGGAGGGCATGATCGCGCTGGTCGGCACCTCCGC
CGCGGGGCTGCTCGATGCCCGCGCCACGCCGCTCGGCCAGGTGATGCCGGGCGTCGCGATCCAGGCCCAGATGATCGAGC
AGATCATCGCTCAGGACTTCATCGAGCGGCCGGACTGGGCCGACGGCTTCGAGATCGTGCTGACGCTGCTGCTGGGCTCG
CTGGTCGCGGCGCTGCTGCTGGTCGCCGGCGCCCGGTTCTCGCTGATCGCCTGCGGCGTGGTGTTTCTCGGCGCGATCGG
CGGATCGTGGATCGCGTTCTCGCATTTCCGCCTGCTGATCGACCCGGTGTATCCATCGCTGGCGACGCTGCTGACCTATG
TCGCCGTCGAGCGCGTGCTGCACATGGCCTCCGACCGCGAGAAGAGATTCGCGCGCCAGGCGTTCGGCCAGTATCTCGCG
CCGGAATTGCTGGCGAAGCTCGAGCAGTCGCCCGACGGAATGCGGCTCGGCGGCGAGACCCGCGATCTCAGCGTGATGTT
CATGGACGTGCGCGGTTTCACCCCGATCTCGGAGACGCTGAGCGCGACCGAATTGGTGGATTTCATCAACACGCTGCTGT
CGCCGCTGTCCGACGCGATCCAGGACGAACTCGGCACGATCGACAAATACATCGGCGACTCGATCATGGCGTTCTGGAAC
GCCCCGGTCGACGTGCCGGATCACGCCGCGCGCGCCTGTCGCGCCGCGCTGAAGATGCGCGCGGTGGTCGAGCAGCTCAA
CGACGCCGACGCCTTCGGCTTCGCGGCGCGCGGCATTGACGATCCGGTGGTGCGGATCGGTGTCGGCATCAACACCGGCG
CGGCCTGCGTCGGCAACATGGGCTCGGCCAAGCGCTTCAACTACTCGGCGATGGGCGATGTGGTGAACGTCGCGGCCCGG
ATCGAGAGCGCGTCGAAGAGCTTCGGCACCGATTTGCTGGTGTCCGAAGACGTCGCCCGCGCCGCGCCGCGAATTGCGCT
GCTCGAGGCCGGCGAGATCATGCTGAAGGGCAAGTCGAAGCCGACCCGGCTCTTCGCGCTTGCGGGCGACGAGGAGGCCG
CGGCGACGCCGGAGTTCGCCGAGTTGCAGCGGTGCCATCGCGCGCTGTTGGACGCGCTAGCGGCCGACGATGCGCGGGCC
GCAGCCGAGGCCCTGGCGAACTGCCGGACTGCTGCGCCGCCGGCACTCGCCGGACTGTACGATCATTTCGCCGAGCGGGT
GGGAGCGATCGGCGGGATGCAGAAGCAGGGCGTCGGATAG

Upstream 100 bases:

>100_bases
GCATCCGGTCCGCCATCGAACCGACAACGTTCGGCCTCATGCGCCAGTTCCATCGTCGAGATTTATCGCCTTGCTGCGGC
GCAACGCGCGGGCTTACACC

Downstream 100 bases:

>100_bases
GCGCGCCGCTCACAACACCGAGACGGCGGCGGGGCGGGGCTCGTGTGCGCCGGGATCGGCGCAGGGCAAAGTGAAACGGA
ACATCGTGCCGCCGGCTGGG

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MRRLSRDAHPFLTRAAPVWVRLRRLTRSKSARAVAAALLTLIALTALRTYDPRLVHETKERAFDAYQRLSPRPHADLPVR
IVDIDEASLAAYGQWPWPRTRLAALTKRLGELGVGVVAYDIIFSEPDRTTPGRLASELGDADLPDRDLTVALLKSLPDHD
QSLAQAMQKTPTVLGFAAIQRANATRPSVKAGLAVVGVQPAFVLPPFRGAVSNLPVLDEAAAGIGAINLSARDRSGVVRR
LPMLMSDGARVYPSLAIEALRVAQNQKGIVVRGTGASGEADTGHAALLDMRVGQFKLPLTPDGEAWLYFNRDRRDRYVSV
KDVLDPAKDAEMRDKLEGMIALVGTSAAGLLDARATPLGQVMPGVAIQAQMIEQIIAQDFIERPDWADGFEIVLTLLLGS
LVAALLLVAGARFSLIACGVVFLGAIGGSWIAFSHFRLLIDPVYPSLATLLTYVAVERVLHMASDREKRFARQAFGQYLA
PELLAKLEQSPDGMRLGGETRDLSVMFMDVRGFTPISETLSATELVDFINTLLSPLSDAIQDELGTIDKYIGDSIMAFWN
APVDVPDHAARACRAALKMRAVVEQLNDADAFGFAARGIDDPVVRIGVGINTGAACVGNMGSAKRFNYSAMGDVVNVAAR
IESASKSFGTDLLVSEDVARAAPRIALLEAGEIMLKGKSKPTRLFALAGDEEAAATPEFAELQRCHRALLDALAADDARA
AAEALANCRTAAPPALAGLYDHFAERVGAIGGMQKQGVG

Sequences:

>Translated_759_residues
MRRLSRDAHPFLTRAAPVWVRLRRLTRSKSARAVAAALLTLIALTALRTYDPRLVHETKERAFDAYQRLSPRPHADLPVR
IVDIDEASLAAYGQWPWPRTRLAALTKRLGELGVGVVAYDIIFSEPDRTTPGRLASELGDADLPDRDLTVALLKSLPDHD
QSLAQAMQKTPTVLGFAAIQRANATRPSVKAGLAVVGVQPAFVLPPFRGAVSNLPVLDEAAAGIGAINLSARDRSGVVRR
LPMLMSDGARVYPSLAIEALRVAQNQKGIVVRGTGASGEADTGHAALLDMRVGQFKLPLTPDGEAWLYFNRDRRDRYVSV
KDVLDPAKDAEMRDKLEGMIALVGTSAAGLLDARATPLGQVMPGVAIQAQMIEQIIAQDFIERPDWADGFEIVLTLLLGS
LVAALLLVAGARFSLIACGVVFLGAIGGSWIAFSHFRLLIDPVYPSLATLLTYVAVERVLHMASDREKRFARQAFGQYLA
PELLAKLEQSPDGMRLGGETRDLSVMFMDVRGFTPISETLSATELVDFINTLLSPLSDAIQDELGTIDKYIGDSIMAFWN
APVDVPDHAARACRAALKMRAVVEQLNDADAFGFAARGIDDPVVRIGVGINTGAACVGNMGSAKRFNYSAMGDVVNVAAR
IESASKSFGTDLLVSEDVARAAPRIALLEAGEIMLKGKSKPTRLFALAGDEEAAATPEFAELQRCHRALLDALAADDARA
AAEALANCRTAAPPALAGLYDHFAERVGAIGGMQKQGVG
>Mature_759_residues
MRRLSRDAHPFLTRAAPVWVRLRRLTRSKSARAVAAALLTLIALTALRTYDPRLVHETKERAFDAYQRLSPRPHADLPVR
IVDIDEASLAAYGQWPWPRTRLAALTKRLGELGVGVVAYDIIFSEPDRTTPGRLASELGDADLPDRDLTVALLKSLPDHD
QSLAQAMQKTPTVLGFAAIQRANATRPSVKAGLAVVGVQPAFVLPPFRGAVSNLPVLDEAAAGIGAINLSARDRSGVVRR
LPMLMSDGARVYPSLAIEALRVAQNQKGIVVRGTGASGEADTGHAALLDMRVGQFKLPLTPDGEAWLYFNRDRRDRYVSV
KDVLDPAKDAEMRDKLEGMIALVGTSAAGLLDARATPLGQVMPGVAIQAQMIEQIIAQDFIERPDWADGFEIVLTLLLGS
LVAALLLVAGARFSLIACGVVFLGAIGGSWIAFSHFRLLIDPVYPSLATLLTYVAVERVLHMASDREKRFARQAFGQYLA
PELLAKLEQSPDGMRLGGETRDLSVMFMDVRGFTPISETLSATELVDFINTLLSPLSDAIQDELGTIDKYIGDSIMAFWN
APVDVPDHAARACRAALKMRAVVEQLNDADAFGFAARGIDDPVVRIGVGINTGAACVGNMGSAKRFNYSAMGDVVNVAAR
IESASKSFGTDLLVSEDVARAAPRIALLEAGEIMLKGKSKPTRLFALAGDEEAAATPEFAELQRCHRALLDALAADDARA
AAEALANCRTAAPPALAGLYDHFAERVGAIGGMQKQGVG

Specific function: Unknown

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI62484298, Length=214, Percent_Identity=27.5700934579439, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62484477, Length=214, Percent_Identity=27.5700934579439, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116008008, Length=214, Percent_Identity=27.5700934579439, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161078020, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 81443; Mature: 81443

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLSRDAHPFLTRAAPVWVRLRRLTRSKSARAVAAALLTLIALTALRTYDPRLVHETKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RAFDAYQRLSPRPHADLPVRIVDIDEASLAAYGQWPWPRTRLAALTKRLGELGVGVVAYD
HHHHHHHHCCCCCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEE
IIFSEPDRTTPGRLASELGDADLPDRDLTVALLKSLPDHDQSLAQAMQKTPTVLGFAAIQ
EEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
RANATRPSVKAGLAVVGVQPAFVLPPFRGAVSNLPVLDEAAAGIGAINLSARDRSGVVRR
HCCCCCCHHHHCEEEEECCCCEECCCCHHHHHCCCCHHHHHCCCCEEEECCCCHHHHHHH
LPMLMSDGARVYPSLAIEALRVAQNQKGIVVRGTGASGEADTGHAALLDMRVGQFKLPLT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEECCCC
PDGEAWLYFNRDRRDRYVSVKDVLDPAKDAEMRDKLEGMIALVGTSAAGLLDARATPLGQ
CCCCEEEEECCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHEECCCHHHHHHCCCCCHHH
VMPGVAIQAQMIEQIIAQDFIERPDWADGFEIVLTLLLGSLVAALLLVAGARFSLIACGV
HCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VFLGAIGGSWIAFSHFRLLIDPVYPSLATLLTYVAVERVLHMASDREKRFARQAFGQYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
PELLAKLEQSPDGMRLGGETRDLSVMFMDVRGFTPISETLSATELVDFINTLLSPLSDAI
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QDELGTIDKYIGDSIMAFWNAPVDVPDHAARACRAALKMRAVVEQLNDADAFGFAARGID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
DPVVRIGVGINTGAACVGNMGSAKRFNYSAMGDVVNVAARIESASKSFGTDLLVSEDVAR
CCEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAPRIALLEAGEIMLKGKSKPTRLFALAGDEEAAATPEFAELQRCHRALLDALAADDARA
HCCCEEEEECCCEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
AAEALANCRTAAPPALAGLYDHFAERVGAIGGMQKQGVG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MRRLSRDAHPFLTRAAPVWVRLRRLTRSKSARAVAAALLTLIALTALRTYDPRLVHETKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RAFDAYQRLSPRPHADLPVRIVDIDEASLAAYGQWPWPRTRLAALTKRLGELGVGVVAYD
HHHHHHHHCCCCCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEE
IIFSEPDRTTPGRLASELGDADLPDRDLTVALLKSLPDHDQSLAQAMQKTPTVLGFAAIQ
EEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHH
RANATRPSVKAGLAVVGVQPAFVLPPFRGAVSNLPVLDEAAAGIGAINLSARDRSGVVRR
HCCCCCCHHHHCEEEEECCCCEECCCCHHHHHCCCCHHHHHCCCCEEEECCCCHHHHHHH
LPMLMSDGARVYPSLAIEALRVAQNQKGIVVRGTGASGEADTGHAALLDMRVGQFKLPLT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEECCCC
PDGEAWLYFNRDRRDRYVSVKDVLDPAKDAEMRDKLEGMIALVGTSAAGLLDARATPLGQ
CCCCEEEEECCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHEECCCHHHHHHCCCCCHHH
VMPGVAIQAQMIEQIIAQDFIERPDWADGFEIVLTLLLGSLVAALLLVAGARFSLIACGV
HCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VFLGAIGGSWIAFSHFRLLIDPVYPSLATLLTYVAVERVLHMASDREKRFARQAFGQYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
PELLAKLEQSPDGMRLGGETRDLSVMFMDVRGFTPISETLSATELVDFINTLLSPLSDAI
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QDELGTIDKYIGDSIMAFWNAPVDVPDHAARACRAALKMRAVVEQLNDADAFGFAARGID
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
DPVVRIGVGINTGAACVGNMGSAKRFNYSAMGDVVNVAARIESASKSFGTDLLVSEDVAR
CCEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAPRIALLEAGEIMLKGKSKPTRLFALAGDEEAAATPEFAELQRCHRALLDALAADDARA
HCCCEEEEECCCEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
AAEALANCRTAAPPALAGLYDHFAERVGAIGGMQKQGVG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]