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The map label for this gene is appC [H]

Identifier: 86750194

GI number: 86750194

Start: 3511375

End: 3512226

Strand: Reverse

Name: appC [H]

Synonym: RPB_3080

Alternate gene names: 86750194

Gene position: 3512226-3511375 (Counterclockwise)

Preceding gene: 86750195

Following gene: 86750193

Centisome position: 65.87

GC content: 62.79

Gene sequence:

>852_bases
ATGAAAGATCGATCCGCTTTTGCCGAGTTTGCCTTGCGCTTCGCCCGTAACCGCGGCGCGCTGCTCGGAATTATCATCAT
TGTCGTCGTGTTGGGACTCGCTCTCGCCGCACCCTGGCTGATCGAACAGAATCCGCTGCGCATCGTCTCGCGGCCGGAGG
TCTGGCCGTTCACCAACCCGCGCTACCCGCTCGGCACCGACTCGATCGGCCGGAACATTCTGGCGATGATAGCCTACGGT
GCTCGAACGACGCTGATGATCGGCATCGTCGCGGCGCTGACTGCGACCGCCATCGGCGTCGTGATCGGTGCCGCCGCGGC
ATGGTTCGGTGGCTGGATTGACGAGGTCCTGACCCGGATCACGGAGCTGTTTCAGACGGTCCCGAACATCCTGTTGATCA
TGACGGTGGTGGCGATCCTGGGCCAGACCATCGACAACATCACGATGGCGATCGGCGTCACGATGTGGCCGGGCATCGCC
CGGCTGACGCGAGCCGAATTCCTTACGCTGAAGAACCGTGAATTCGTGCTGGCGTGCCGTTCGATGGGCATGAGCAACAT
CAGGATCATGGCGGGCGAAATCCTGCCCAACGCGATTCCGCCGGTGATCGTGCTCGCCTCGGTGATCATCGGCAGCTCGA
TCCTGTTCGAGAGCGCGATCTCGTTTCTCGGTCTCGGCGATCCCAATGTCGCGAGCTGGGGCGCGCTGATCGGCGACGGC
CGCACGTTGATCCGCCGCTCCTGGTACATCTGCGCGATCCCCGGCGTTGCGATCATGCTGACGGTGCTGGCGATGAACCT
GATCGGCGATGGGCTGAATGACGCGCTCAATCCCAAGCTGAGGGACCGCTGA

Upstream 100 bases:

>100_bases
TGGGCGTCTTCGTTCTGTCGGCGGTCGTCGTCGCCGTCGCCAATCTGCTGGTCGATCTTGCCTACTACCGGCTTGATCCG
CGAATCCGGAGCCGATGAAC

Downstream 100 bases:

>100_bases
GATGGCGGCGCTGCTCGAAATTCGCGATCTCGAAGTTGATCTGTTCACGCGGCGCGGCGTGATGCGCGCGATCGACCGCT
TTTCCCTCACCGTCGAACAC

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKDRSAFAEFALRFARNRGALLGIIIIVVVLGLALAAPWLIEQNPLRIVSRPEVWPFTNPRYPLGTDSIGRNILAMIAYG
ARTTLMIGIVAALTATAIGVVIGAAAAWFGGWIDEVLTRITELFQTVPNILLIMTVVAILGQTIDNITMAIGVTMWPGIA
RLTRAEFLTLKNREFVLACRSMGMSNIRIMAGEILPNAIPPVIVLASVIIGSSILFESAISFLGLGDPNVASWGALIGDG
RTLIRRSWYICAIPGVAIMLTVLAMNLIGDGLNDALNPKLRDR

Sequences:

>Translated_283_residues
MKDRSAFAEFALRFARNRGALLGIIIIVVVLGLALAAPWLIEQNPLRIVSRPEVWPFTNPRYPLGTDSIGRNILAMIAYG
ARTTLMIGIVAALTATAIGVVIGAAAAWFGGWIDEVLTRITELFQTVPNILLIMTVVAILGQTIDNITMAIGVTMWPGIA
RLTRAEFLTLKNREFVLACRSMGMSNIRIMAGEILPNAIPPVIVLASVIIGSSILFESAISFLGLGDPNVASWGALIGDG
RTLIRRSWYICAIPGVAIMLTVLAMNLIGDGLNDALNPKLRDR
>Mature_283_residues
MKDRSAFAEFALRFARNRGALLGIIIIVVVLGLALAAPWLIEQNPLRIVSRPEVWPFTNPRYPLGTDSIGRNILAMIAYG
ARTTLMIGIVAALTATAIGVVIGAAAAWFGGWIDEVLTRITELFQTVPNILLIMTVVAILGQTIDNITMAIGVTMWPGIA
RLTRAEFLTLKNREFVLACRSMGMSNIRIMAGEILPNAIPPVIVLASVIIGSSILFESAISFLGLGDPNVASWGALIGDG
RTLIRRSWYICAIPGVAIMLTVLAMNLIGDGLNDALNPKLRDR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=33.6917562724014, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1787760, Length=256, Percent_Identity=33.984375, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=37.8571428571429, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787498, Length=285, Percent_Identity=35.7894736842105, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=33.0612244897959, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787549, Length=243, Percent_Identity=31.2757201646091, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788505, Length=232, Percent_Identity=30.6034482758621, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30490; Mature: 30490

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRSAFAEFALRFARNRGALLGIIIIVVVLGLALAAPWLIEQNPLRIVSRPEVWPFTNP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEECCCCCCCCCCC
RYPLGTDSIGRNILAMIAYGARTTLMIGIVAALTATAIGVVIGAAAAWFGGWIDEVLTRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TELFQTVPNILLIMTVVAILGQTIDNITMAIGVTMWPGIARLTRAEFLTLKNREFVLACR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
SMGMSNIRIMAGEILPNAIPPVIVLASVIIGSSILFESAISFLGLGDPNVASWGALIGDG
HCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
RTLIRRSWYICAIPGVAIMLTVLAMNLIGDGLNDALNPKLRDR
HHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
>Mature Secondary Structure
MKDRSAFAEFALRFARNRGALLGIIIIVVVLGLALAAPWLIEQNPLRIVSRPEVWPFTNP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCEEECCCCCCCCCCC
RYPLGTDSIGRNILAMIAYGARTTLMIGIVAALTATAIGVVIGAAAAWFGGWIDEVLTRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TELFQTVPNILLIMTVVAILGQTIDNITMAIGVTMWPGIARLTRAEFLTLKNREFVLACR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
SMGMSNIRIMAGEILPNAIPPVIVLASVIIGSSILFESAISFLGLGDPNVASWGALIGDG
HCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
RTLIRRSWYICAIPGVAIMLTVLAMNLIGDGLNDALNPKLRDR
HHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]