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The map label for this gene is sufC [H]

Identifier: 86750109

GI number: 86750109

Start: 3406281

End: 3407039

Strand: Reverse

Name: sufC [H]

Synonym: RPB_2992

Alternate gene names: 86750109

Gene position: 3407039-3406281 (Counterclockwise)

Preceding gene: 86750110

Following gene: 86750108

Centisome position: 63.9

GC content: 64.69

Gene sequence:

>759_bases
ATGTCCGCATTGCTCGAAGTCAAGAATCTCCAGGTCCGCGTCGCCGAGCGCGAGATCCTGCATGGGCTGACGCTCAGCGT
GAATCCGGGTGAGGTGCACGCGATCATGGGGCCGAACGGCTCCGGCAAGTCGACGCTGTCGCATGTGATCGCCGGCAAGC
CGGGCTACGAAGTCACCGGCGGCGAGATCCTGTTCAAGGGCGAGGATCTGCTGGCGATGGCGCCGGACGAGCGCGCCGCC
AAGGGCGTGTTCCTGGCATTTCAGTATCCGGTCGAAATTCCCGGCGTGGCGACGATGACGTTCCTGCGCACCGCGCTGAA
CGCGCAGCGCAAGTCGCGCGGCGAAGCCGAACTGTCGACGCCGGATTTCCTCAAGCGCGTGCGTGAAGTGGCGGGTTCGC
TCGGCATTCCGCAGGAGATGCTGAAGCGCGGCGTCAATGTCGGCTTCTCCGGCGGCGAGAAGAAGCGCAACGAAGTGCTG
CAGATGGCGCTGTTTCAGCCGAGCCTGTGCATCCTCGACGAGATGGATTCCGGCCTCGACATCGACGCGCTGCGCATCGC
CTCCGAAGGCGTCAACGCGCTGCGCACGCCGGACCGGGCGATGGTGGTGATCACGCATTATCAGCGGCTGCTCGACTACA
TCGTGCCGGACTTCGTGCATGTGATGTCGCGCGGCAAGGTGGTGAAGAGCGGCGGCAAGGAGCTGGCGCTCGAACTCGAA
GCCAATGGCTACGCGCAATATCAGGACGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
CCCGTCTCGACCGCATCGAAAAGCGGCTCGATCTCGTGGATTGAATTTACGGGGATGGCGCGCGCGTCGCGTATCTCCGA
CTGAGATAAAGGAAGCACCG

Downstream 100 bases:

>100_bases
GGCGGATCGGACGGATCAGATGAATATCGCAGTGGCGAAGACCGACAAGATGGATATGGCCGGGGCGAATTTGGCCAGCG
TCGTCGCGCGCCAGCCGGAT

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSALLEVKNLQVRVAEREILHGLTLSVNPGEVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMAPDERAA
KGVFLAFQYPVEIPGVATMTFLRTALNAQRKSRGEAELSTPDFLKRVREVAGSLGIPQEMLKRGVNVGFSGGEKKRNEVL
QMALFQPSLCILDEMDSGLDIDALRIASEGVNALRTPDRAMVVITHYQRLLDYIVPDFVHVMSRGKVVKSGGKELALELE
ANGYAQYQDAAA

Sequences:

>Translated_252_residues
MSALLEVKNLQVRVAEREILHGLTLSVNPGEVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMAPDERAA
KGVFLAFQYPVEIPGVATMTFLRTALNAQRKSRGEAELSTPDFLKRVREVAGSLGIPQEMLKRGVNVGFSGGEKKRNEVL
QMALFQPSLCILDEMDSGLDIDALRIASEGVNALRTPDRAMVVITHYQRLLDYIVPDFVHVMSRGKVVKSGGKELALELE
ANGYAQYQDAAA
>Mature_251_residues
SALLEVKNLQVRVAEREILHGLTLSVNPGEVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMAPDERAAK
GVFLAFQYPVEIPGVATMTFLRTALNAQRKSRGEAELSTPDFLKRVREVAGSLGIPQEMLKRGVNVGFSGGEKKRNEVLQ
MALFQPSLCILDEMDSGLDIDALRIASEGVNALRTPDRAMVVITHYQRLLDYIVPDFVHVMSRGKVVKSGGKELALELEA
NGYAQYQDAAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=220, Percent_Identity=28.6363636363636, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787972, Length=242, Percent_Identity=58.6776859504132, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=24.7933884297521, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786698, Length=206, Percent_Identity=27.6699029126214, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789751, Length=224, Percent_Identity=30.8035714285714, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787500, Length=218, Percent_Identity=29.3577981651376, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789672, Length=238, Percent_Identity=24.7899159663866, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081791, Length=246, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=23.8493723849372, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787370, Length=236, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=232, Percent_Identity=26.7241379310345, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=239, Percent_Identity=29.7071129707113, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=237, Percent_Identity=27.4261603375527, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=251, Percent_Identity=27.0916334661355, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27275; Mature: 27144

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALLEVKNLQVRVAEREILHGLTLSVNPGEVHAIMGPNGSGKSTLSHVIAGKPGYEVTG
CCCHHHHHCCEEEEHHHHHHCCEEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCEECC
GEILFKGEDLLAMAPDERAAKGVFLAFQYPVEIPGVATMTFLRTALNAQRKSRGEAELST
CEEEEECCCEEEECCCCHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
PDFLKRVREVAGSLGIPQEMLKRGVNVGFSGGEKKRNEVLQMALFQPSLCILDEMDSGLD
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCC
IDALRIASEGVNALRTPDRAMVVITHYQRLLDYIVPDFVHVMSRGKVVKSGGKELALELE
HHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEE
ANGYAQYQDAAA
CCCCCCCCCCCC
>Mature Secondary Structure 
SALLEVKNLQVRVAEREILHGLTLSVNPGEVHAIMGPNGSGKSTLSHVIAGKPGYEVTG
CCHHHHHCCEEEEHHHHHHCCEEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCEECC
GEILFKGEDLLAMAPDERAAKGVFLAFQYPVEIPGVATMTFLRTALNAQRKSRGEAELST
CEEEEECCCEEEECCCCHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
PDFLKRVREVAGSLGIPQEMLKRGVNVGFSGGEKKRNEVLQMALFQPSLCILDEMDSGLD
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCC
IDALRIASEGVNALRTPDRAMVVITHYQRLLDYIVPDFVHVMSRGKVVKSGGKELALELE
HHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEE
ANGYAQYQDAAA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]