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The map label for this gene is yngE [H]

Identifier: 86750051

GI number: 86750051

Start: 3346154

End: 3347758

Strand: Reverse

Name: yngE [H]

Synonym: RPB_2934

Alternate gene names: 86750051

Gene position: 3347758-3346154 (Counterclockwise)

Preceding gene: 86750052

Following gene: 86750050

Centisome position: 62.79

GC content: 66.85

Gene sequence:

>1605_bases
ATGTCGCTGCATTCCCAGATCGATCCCGGCTCGTCCGAATTCGCGCGCAATGCCGAGGCGATGCGCGCGCTGGTCGCAGA
GCTGAAGGACAAGCTCGACGACGTCGCCGGCGGTGGTGGCGGGGCGTCGCGCGCCAAGCACACCGCGCGCGGCAAGCTGC
TGGCGCGCGACCGCGTCGACCTACTGCTCGACCCCGGCACCGCGTTTCTCGAACTGTCGCCGCTCGCCGCCAACGGCCTC
TATGGCGGCGACGTGCATTCGGCCTCGATCGTCACCGGCGTCGGTCGCGTCATGGGCCGCGAATGCATGATCGTCGCCAA
CGACGCCACGGTGAAGGGCGGCACCTATTATCCGCTGACGGTGAAGAAGCATCTGCGCGCGCAGGACATCGCGCGGCAGA
ACAACTTGCCGTGCATCTACATGGTCGACTCCGGCGGCGCCTTCCTGCCGCAGCAGGACGAGGTGTTTCCCGACGAGCGG
CATTTCGGCCGGATCTTCTTCAACCAGGCCAACATGTCGGCTGCGGGCATCCCGCAGATCGCAGTGGTGATGGGCTCGTG
CACCGCCGGCGGCGCTTACGTGCCGGCGATGTCGGACGAGAGCATCATCGTGCGCAATCAGGGCACCATCTTCCTCGGCG
GCCCGCCGCTGGTGAAGGCCGCGACCGGCGAGGTGGTCTCCGCCGAAGAGCTCGGCGGCGCCGACGTGCATTCCCGGCAG
TCCGGCGTCACCGATCACTACGCGCAGAACGACGCCCACGCCATCGGCATCGCGCGGAAAATCGTCGGCACCTTGAAGCC
GCCGCAGCGGGCGCTTCTCAACATGCGCGCGCCGCGCGAGCCGCTGTATCCGGCCGAGCAGCTCTATGGAATTGTCCCGG
CTGAGCAGCGCAAGCCGTTCGACGTGCGCGATATCATCGCCCGGATCGTCGACGGCTCGGAGTTCGACGAGTTCAAGAAG
CTGTACGGCCAGACGCTGGTCTGCGGCTTCGCGCATATCTGGGGCTTTCCGGTCGGCATCATCGCCAATAACGGCATCCT
GTTCAGCGAATCTTCGCTGAAGGGCGCGCATTTCATCGAGCTGTGCTGCCAGCGCGGCATCCCGCTGGTGTTCCTGCAGA
ACATCACCGGCTTCATGGTCGGCAAGAAGTACGAGGCCGGCGGCATTGCCCGCGACGGCGCCAAGCTGGTCACCGCGGTC
GCCACCGCCAATGTGCCGAAATTCACCATCGTGATCGGCGGCTCCTACGGCGCGGGCAATTACGGCATGTGCGGCCGGGC
CTATTCGCCGCGATTTCTGTGGATGTGGCCGAACGCGCGGATCTCGGTGATGGGCGGCGAGCAGGCGGCGATGGTGCTGA
GCACGCTGCGCCGCGACAACATCGAGGCCAAGGGCGGCGCCTGGAGCACGGAGGAGGAAGAGGAATTCCGCTCCCCGATC
CGCGCCCAATACGAGACGCAGGGCAGCCCGTATTACGCGACCGCGCGGCTGTGGGACGACGGGGTGATCGACCCCGCCGA
CACCCGGCTGGTGCTGGGTCTCGGGCTGTCGGCGTCGGCGAATGCGCCGATCGAGCCGACGACATTCGGCCTGTTCAGGA
TGTGA

Upstream 100 bases:

>100_bases
TTCGGAGCGCCGCAGGTTGGGGTTGCGTCCTGCGCCCGCGCGATGACACCATGATCCGAACGCTTCATCCCCGAGGCGAG
CCATAAAAGCCGGAAACGCC

Downstream 100 bases:

>100_bases
TGATGGCAACGACAGGCTTGTACAAGCGCTTCCGCACGCTGCTGATCGCCAACCGCGGCGAGATCGCCTGCCGCGTCATC
CGCACCGCGCGGGCGATGGG

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSLHSQIDPGSSEFARNAEAMRALVAELKDKLDDVAGGGGGASRAKHTARGKLLARDRVDLLLDPGTAFLELSPLAANGL
YGGDVHSASIVTGVGRVMGRECMIVANDATVKGGTYYPLTVKKHLRAQDIARQNNLPCIYMVDSGGAFLPQQDEVFPDER
HFGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEVVSAEELGGADVHSRQ
SGVTDHYAQNDAHAIGIARKIVGTLKPPQRALLNMRAPREPLYPAEQLYGIVPAEQRKPFDVRDIIARIVDGSEFDEFKK
LYGQTLVCGFAHIWGFPVGIIANNGILFSESSLKGAHFIELCCQRGIPLVFLQNITGFMVGKKYEAGGIARDGAKLVTAV
ATANVPKFTIVIGGSYGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAAMVLSTLRRDNIEAKGGAWSTEEEEEFRSPI
RAQYETQGSPYYATARLWDDGVIDPADTRLVLGLGLSASANAPIEPTTFGLFRM

Sequences:

>Translated_534_residues
MSLHSQIDPGSSEFARNAEAMRALVAELKDKLDDVAGGGGGASRAKHTARGKLLARDRVDLLLDPGTAFLELSPLAANGL
YGGDVHSASIVTGVGRVMGRECMIVANDATVKGGTYYPLTVKKHLRAQDIARQNNLPCIYMVDSGGAFLPQQDEVFPDER
HFGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEVVSAEELGGADVHSRQ
SGVTDHYAQNDAHAIGIARKIVGTLKPPQRALLNMRAPREPLYPAEQLYGIVPAEQRKPFDVRDIIARIVDGSEFDEFKK
LYGQTLVCGFAHIWGFPVGIIANNGILFSESSLKGAHFIELCCQRGIPLVFLQNITGFMVGKKYEAGGIARDGAKLVTAV
ATANVPKFTIVIGGSYGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAAMVLSTLRRDNIEAKGGAWSTEEEEEFRSPI
RAQYETQGSPYYATARLWDDGVIDPADTRLVLGLGLSASANAPIEPTTFGLFRM
>Mature_533_residues
SLHSQIDPGSSEFARNAEAMRALVAELKDKLDDVAGGGGGASRAKHTARGKLLARDRVDLLLDPGTAFLELSPLAANGLY
GGDVHSASIVTGVGRVMGRECMIVANDATVKGGTYYPLTVKKHLRAQDIARQNNLPCIYMVDSGGAFLPQQDEVFPDERH
FGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEVVSAEELGGADVHSRQS
GVTDHYAQNDAHAIGIARKIVGTLKPPQRALLNMRAPREPLYPAEQLYGIVPAEQRKPFDVRDIIARIVDGSEFDEFKKL
YGQTLVCGFAHIWGFPVGIIANNGILFSESSLKGAHFIELCCQRGIPLVFLQNITGFMVGKKYEAGGIARDGAKLVTAVA
TANVPKFTIVIGGSYGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAAMVLSTLRRDNIEAKGGAWSTEEEEEFRSPIR
AQYETQGSPYYATARLWDDGVIDPADTRLVLGLGLSASANAPIEPTTFGLFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=534, Percent_Identity=64.0449438202247, Blast_Score=710, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=509, Percent_Identity=34.1846758349705, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI295821216, Length=529, Percent_Identity=33.0812854442344, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI310133460, Length=144, Percent_Identity=55.5555555555556, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17552936, Length=533, Percent_Identity=62.1013133208255, Blast_Score=702, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=499, Percent_Identity=35.2705410821643, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI25147359, Length=499, Percent_Identity=35.2705410821643, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586065, Length=549, Percent_Identity=64.6630236794171, Blast_Score=733, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 57272; Mature: 57141

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHSQIDPGSSEFARNAEAMRALVAELKDKLDDVAGGGGGASRAKHTARGKLLARDRVD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCEE
LLLDPGTAFLELSPLAANGLYGGDVHSASIVTGVGRVMGRECMIVANDATVKGGTYYPLT
EEECCCCEEEEECCHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEECCCEEEEEE
VKKHLRAQDIARQNNLPCIYMVDSGGAFLPQQDEVFPDERHFGRIFFNQANMSAAGIPQI
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEE
AVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEVVSAEELGGADVHSRQ
EEEEECCCCCCEEEECCCCCEEEEEECCEEEECCCCEEEECCCCEEEHHHCCCCCCHHCC
SGVTDHYAQNDAHAIGIARKIVGTLKPPQRALLNMRAPREPLYPAEQLYGIVPAEQRKPF
CCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCCC
DVRDIIARIVDGSEFDEFKKLYGQTLVCGFAHIWGFPVGIIANNGILFSESSLKGAHFIE
CHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHHH
LCCQRGIPLVFLQNITGFMVGKKYEAGGIARDGAKLVTAVATANVPKFTIVIGGSYGAGN
HHHHCCCCEEEECCCCHHEECCEECCCCCCCCCHHHEEHHHHCCCCEEEEEEECCCCCCC
YGMCGRAYSPRFLWMWPNARISVMGGEQAAMVLSTLRRDNIEAKGGAWSTEEEEEFRSPI
CCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHH
RAQYETQGSPYYATARLWDDGVIDPADTRLVLGLGLSASANAPIEPTTFGLFRM
HEEHCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
SLHSQIDPGSSEFARNAEAMRALVAELKDKLDDVAGGGGGASRAKHTARGKLLARDRVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCEE
LLLDPGTAFLELSPLAANGLYGGDVHSASIVTGVGRVMGRECMIVANDATVKGGTYYPLT
EEECCCCEEEEECCHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEECCCEEEEEE
VKKHLRAQDIARQNNLPCIYMVDSGGAFLPQQDEVFPDERHFGRIFFNQANMSAAGIPQI
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEE
AVVMGSCTAGGAYVPAMSDESIIVRNQGTIFLGGPPLVKAATGEVVSAEELGGADVHSRQ
EEEEECCCCCCEEEECCCCCEEEEEECCEEEECCCCEEEECCCCEEEHHHCCCCCCHHCC
SGVTDHYAQNDAHAIGIARKIVGTLKPPQRALLNMRAPREPLYPAEQLYGIVPAEQRKPF
CCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCCC
DVRDIIARIVDGSEFDEFKKLYGQTLVCGFAHIWGFPVGIIANNGILFSESSLKGAHFIE
CHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHHH
LCCQRGIPLVFLQNITGFMVGKKYEAGGIARDGAKLVTAVATANVPKFTIVIGGSYGAGN
HHHHCCCCEEEECCCCHHEECCEECCCCCCCCCHHHEEHHHHCCCCEEEEEEECCCCCCC
YGMCGRAYSPRFLWMWPNARISVMGGEQAAMVLSTLRRDNIEAKGGAWSTEEEEEFRSPI
CCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHH
RAQYETQGSPYYATARLWDDGVIDPADTRLVLGLGLSASANAPIEPTTFGLFRM
HEEHCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]