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The map label for this gene is coaD

Identifier: 86749991

GI number: 86749991

Start: 3270912

End: 3271409

Strand: Reverse

Name: coaD

Synonym: RPB_2874

Alternate gene names: 86749991

Gene position: 3271409-3270912 (Counterclockwise)

Preceding gene: 86749993

Following gene: 86749990

Centisome position: 61.36

GC content: 66.87

Gene sequence:

>498_bases
ATGTCCCGTATCGCGCTGTATCCCGGCTCCTTCGACCCCGTCACCAACGGCCATCTCGACGTCGTCCGCCACGCGGTCGA
ATTGTGCGACAGGCTGGTGGTGGCGATCGGCATCCACCCCGGCAAGAAGCCGCTGTTCACCACCGAGGAGCGGCTGGTGA
TGGTGCGACGCGTGTTCGAGCCGGTCGCCGAGGCCGCCGGCTGTGCGTTCGATTGCACCACCTACGACAATCTCACGGTC
ACCGCGGCGCAGCAGGTCGGCGCGTCGCTGATGATCCGCGGGCTGCGCGACGGCACTGATCTCGACTACGAAATGCAGAT
CGCCGGCATGAACGAGACCATGGCGCCGGGGGTCCACACGGTGTTTTTGCCGGCGTCGGTCGGCGTGCGCCCGATCACCG
CCACACTGGTGCGGCAGATCGCTGCGATGGGCGGCGACGTCTCCGCCTTCGTGCCGCCCGATGTCGCGGCCAGTCTGAAA
TCGAAATTCGCCGGCTAG

Upstream 100 bases:

>100_bases
AGGTGGCCTTCCGGTTCGATCCGCAGAGCGAAATAAAACCCCGGACAGGGCCGGAACCAGATCGGCTTGCGGGCGTCATG
CGGCCGCGCTAGACGGAAGC

Downstream 100 bases:

>100_bases
CCGGCTTTTGCAATCCGGAGTTTCCATGATCCGTTTGATAGGCATCATCGCCGCGCTGGTGTTCGCTCTGCCCGCGCTGG
CGCAGCCGCTGCCCGCCGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSRIALYPGSFDPVTNGHLDVVRHAVELCDRLVVAIGIHPGKKPLFTTEERLVMVRRVFEPVAEAAGCAFDCTTYDNLTV
TAAQQVGASLMIRGLRDGTDLDYEMQIAGMNETMAPGVHTVFLPASVGVRPITATLVRQIAAMGGDVSAFVPPDVAASLK
SKFAG

Sequences:

>Translated_165_residues
MSRIALYPGSFDPVTNGHLDVVRHAVELCDRLVVAIGIHPGKKPLFTTEERLVMVRRVFEPVAEAAGCAFDCTTYDNLTV
TAAQQVGASLMIRGLRDGTDLDYEMQIAGMNETMAPGVHTVFLPASVGVRPITATLVRQIAAMGGDVSAFVPPDVAASLK
SKFAG
>Mature_164_residues
SRIALYPGSFDPVTNGHLDVVRHAVELCDRLVVAIGIHPGKKPLFTTEERLVMVRRVFEPVAEAAGCAFDCTTYDNLTVT
AAQQVGASLMIRGLRDGTDLDYEMQIAGMNETMAPGVHTVFLPASVGVRPITATLVRQIAAMGGDVSAFVPPDVAASLKS
KFAG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=164, Percent_Identity=38.4146341463415, Blast_Score=130, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_RHOP2 (Q2IW34)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486487.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q2IW34
- SMR:   Q2IW34
- STRING:   Q2IW34
- GeneID:   3910668
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2874
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   RPAL316058:RPB_2874-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17559; Mature: 17427

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIALYPGSFDPVTNGHLDVVRHAVELCDRLVVAIGIHPGKKPLFTTEERLVMVRRVFE
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHH
PVAEAAGCAFDCTTYDNLTVTAAQQVGASLMIRGLRDGTDLDYEMQIAGMNETMAPGVHT
HHHHHCCCEEECCCCCCEEEEHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEE
VFLPASVGVRPITATLVRQIAAMGGDVSAFVPPDVAASLKSKFAG
EEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCC
>Mature Secondary Structure 
SRIALYPGSFDPVTNGHLDVVRHAVELCDRLVVAIGIHPGKKPLFTTEERLVMVRRVFE
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHH
PVAEAAGCAFDCTTYDNLTVTAAQQVGASLMIRGLRDGTDLDYEMQIAGMNETMAPGVHT
HHHHHCCCEEECCCCCCEEEEHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEE
VFLPASVGVRPITATLVRQIAAMGGDVSAFVPPDVAASLKSKFAG
EEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA