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The map label for this gene is mdtA [H]

Identifier: 86749874

GI number: 86749874

Start: 3144029

End: 3145159

Strand: Reverse

Name: mdtA [H]

Synonym: RPB_2757

Alternate gene names: 86749874

Gene position: 3145159-3144029 (Counterclockwise)

Preceding gene: 86749881

Following gene: 86749873

Centisome position: 58.99

GC content: 64.63

Gene sequence:

>1131_bases
ATGGCCAAACGTCGCTGGATCATCATTGCCTGCTTTCTGGGCATTTCCGCAGGGGCCGCTGTTGTCCTGCAGCCGTACTG
GTCGAAAAGCCAGGTCGCGACCAAAAGCGCGCCGCGGACGCGTGTGGTCACGGTCGATCTGGACAAGGCGGTGCGGAAAC
CGATCCCGGTCGATGTCGACGCGATCGGCATGGTGACGCCGATCTCCAGCGTTGCGCTGAAATCCAGGCTCGAAACCACC
ATCGTCGACGTCCATTTCGAGGACGGCGCGCGGGTCAAGCAAGGCGATCTGTTGTTCACGCTCGACTCGCGCCAGATCGA
CGCCCAGATCGAGCAGGCCGAAGGCAATCTCGCCCGCGACCGCGCCCAGCTCGCCGGCGCCGAACGGGACTTGCGCCGCT
ATAACGAATTGATCGGGAAGGGCGCCACCACCCAGGTCAACCTCGACAACGCCAAGACCCAGGCCGACATCCTCGCGGGA
ACCATCAGGGGCGCCCAGTCGGCGCTGGATAATCTGCGGGTCCAGAAAAGCTATACTGCGATCCGCGCGCCGTTCTCCGG
CCGGATCAGCGCCGCCAACGTCAAAATCGGCAATTTCGTCCGCCCCGCGGACACCGCGCCGTTGGCGACGATCAACCAGA
TGGCGCCGGTCTATGTCACTTTCGCCGTCCCGCAGCGGGTTCTGGTCGATCTGCGCGATGCGATGAAAGCAGGCGCCACC
AAGGTGGTCGCTACCATTCCCGGGAGCGGCCGATCCGAGGAGGGCAAGGTGGCAATGGTCGAGAACACCGTCGACGCCAC
CACCGGCATGGTCACGGTCCGCGGCGTCATGGAAAACAGCAACGAGACGCTGTGGCCGGGAACGCTGGTCAATACCAAGC
TCACCGTTCGGACCGAGGAGGCCGTTGCGGTGCCCACCGTGGCGGTGCAACGCAGTCAGGGCGGCAATTTTGTGTTCGTG
ATCAAGAACGGCGTTGCGCACGTCCAGCCGGTCACCGTCAGCCGCACCTTCATGGGAGAGTCCGTCATCACCGATGGCCT
TGCTGGCGGCGAAGACGTGGTGACGGACGGCCAGTTGCTGCTGTCGGAAGGCACCAGGGTCGAGCCGCGCAGCCGCAGGG
CCGGAGCCTGA

Upstream 100 bases:

>100_bases
GGGGGCTGTGGTAAGCCTCAGAAAAATCGGGCGTAATGACGCCTCGGGAGCGCGCGGGCGGTGGATGCCGTCGGGCGTGG
CAAGATCAACGCGGAGCGTC

Downstream 100 bases:

>100_bases
GACCATGACCCTTTCCGAGCTGTGCATCCGGCGGCCGGTTCTGACCACGCTGATCACCGCGTCGATCATCGCCTTCGGGA
TCTTCGGCTATCGACTGCTG

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAKRRWIIIACFLGISAGAAVVLQPYWSKSQVATKSAPRTRVVTVDLDKAVRKPIPVDVDAIGMVTPISSVALKSRLETT
IVDVHFEDGARVKQGDLLFTLDSRQIDAQIEQAEGNLARDRAQLAGAERDLRRYNELIGKGATTQVNLDNAKTQADILAG
TIRGAQSALDNLRVQKSYTAIRAPFSGRISAANVKIGNFVRPADTAPLATINQMAPVYVTFAVPQRVLVDLRDAMKAGAT
KVVATIPGSGRSEEGKVAMVENTVDATTGMVTVRGVMENSNETLWPGTLVNTKLTVRTEEAVAVPTVAVQRSQGGNFVFV
IKNGVAHVQPVTVSRTFMGESVITDGLAGGEDVVTDGQLLLSEGTRVEPRSRRAGA

Sequences:

>Translated_376_residues
MAKRRWIIIACFLGISAGAAVVLQPYWSKSQVATKSAPRTRVVTVDLDKAVRKPIPVDVDAIGMVTPISSVALKSRLETT
IVDVHFEDGARVKQGDLLFTLDSRQIDAQIEQAEGNLARDRAQLAGAERDLRRYNELIGKGATTQVNLDNAKTQADILAG
TIRGAQSALDNLRVQKSYTAIRAPFSGRISAANVKIGNFVRPADTAPLATINQMAPVYVTFAVPQRVLVDLRDAMKAGAT
KVVATIPGSGRSEEGKVAMVENTVDATTGMVTVRGVMENSNETLWPGTLVNTKLTVRTEEAVAVPTVAVQRSQGGNFVFV
IKNGVAHVQPVTVSRTFMGESVITDGLAGGEDVVTDGQLLLSEGTRVEPRSRRAGA
>Mature_375_residues
AKRRWIIIACFLGISAGAAVVLQPYWSKSQVATKSAPRTRVVTVDLDKAVRKPIPVDVDAIGMVTPISSVALKSRLETTI
VDVHFEDGARVKQGDLLFTLDSRQIDAQIEQAEGNLARDRAQLAGAERDLRRYNELIGKGATTQVNLDNAKTQADILAGT
IRGAQSALDNLRVQKSYTAIRAPFSGRISAANVKIGNFVRPADTAPLATINQMAPVYVTFAVPQRVLVDLRDAMKAGATK
VVATIPGSGRSEEGKVAMVENTVDATTGMVTVRGVMENSNETLWPGTLVNTKLTVRTEEAVAVPTVAVQRSQGGNFVFVI
KNGVAHVQPVTVSRTFMGESVITDGLAGGEDVVTDGQLLLSEGTRVEPRSRRAGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=325, Percent_Identity=33.5384615384615, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789665, Length=364, Percent_Identity=26.3736263736264, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786668, Length=351, Percent_Identity=25.0712250712251, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789929, Length=306, Percent_Identity=24.1830065359477, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40157; Mature: 40026

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRRWIIIACFLGISAGAAVVLQPYWSKSQVATKSAPRTRVVTVDLDKAVRKPIPVDVD
CCCCEEEEEEEEECCCCCCEEEEECCCCCCHHHHCCCCCEEEEEEEHHHHHCCCCCCCCC
AIGMVTPISSVALKSRLETTIVDVHFEDGARVKQGDLLFTLDSRQIDAQIEQAEGNLARD
CCCCCCCHHHHHHHHCCCEEEEEEEECCCCEEECCCEEEEECCCEECCCHHHCCCCHHHH
RAQLAGAERDLRRYNELIGKGATTQVNLDNAKTQADILAGTIRGAQSALDNLRVQKSYTA
HHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECCEE
IRAPFSGRISAANVKIGNFVRPADTAPLATINQMAPVYVTFAVPQRVLVDLRDAMKAGAT
EECCCCCCEEEEEEEECCEECCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCE
KVVATIPGSGRSEEGKVAMVENTVDATTGMVTVRGVMENSNETLWPGTLVNTKLTVRTEE
EEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCEECCCEEECCEEEEEECC
AVAVPTVAVQRSQGGNFVFVIKNGVAHVQPVTVSRTFMGESVITDGLAGGEDVVTDGQLL
CEECCEEEEEECCCCCEEEEEECCCCEEEEEEEEHHHCCCHHHHCCCCCCCCEEECCEEE
LSEGTRVEPRSRRAGA
ECCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKRRWIIIACFLGISAGAAVVLQPYWSKSQVATKSAPRTRVVTVDLDKAVRKPIPVDVD
CCCEEEEEEEEECCCCCCEEEEECCCCCCHHHHCCCCCEEEEEEEHHHHHCCCCCCCCC
AIGMVTPISSVALKSRLETTIVDVHFEDGARVKQGDLLFTLDSRQIDAQIEQAEGNLARD
CCCCCCCHHHHHHHHCCCEEEEEEEECCCCEEECCCEEEEECCCEECCCHHHCCCCHHHH
RAQLAGAERDLRRYNELIGKGATTQVNLDNAKTQADILAGTIRGAQSALDNLRVQKSYTA
HHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEECCEE
IRAPFSGRISAANVKIGNFVRPADTAPLATINQMAPVYVTFAVPQRVLVDLRDAMKAGAT
EECCCCCCEEEEEEEECCEECCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCE
KVVATIPGSGRSEEGKVAMVENTVDATTGMVTVRGVMENSNETLWPGTLVNTKLTVRTEE
EEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCEECCCEEECCEEEEEECC
AVAVPTVAVQRSQGGNFVFVIKNGVAHVQPVTVSRTFMGESVITDGLAGGEDVVTDGQLL
CEECCEEEEEECCCCCEEEEEECCCCEEEEEEEEHHHCCCHHHHCCCCCCCCEEECCEEE
LSEGTRVEPRSRRAGA
ECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA