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The map label for this gene is argS

Identifier: 86749867

GI number: 86749867

Start: 3134215

End: 3136008

Strand: Reverse

Name: argS

Synonym: RPB_2750

Alternate gene names: 86749867

Gene position: 3136008-3134215 (Counterclockwise)

Preceding gene: 86749868

Following gene: 86749866

Centisome position: 58.82

GC content: 65.05

Gene sequence:

>1794_bases
ATGCCCGATCAAACCACGTCCACGCATCTGTTCGCCCATATCCTCGCGCGCGTGCACGCGGTCTGCGCCGCGCTGACCGA
CGAGGGCGCGCTGCCCACGGGAACCGACCTGTCGCGCATCGTGGTCGAACCGCCCAAGGACGCCTCCCACGGCGACATGG
CGACCAATGCGGCGATGGTGCTCGCCAAGGACGCCAAGGCCAAACCGCGCGACCTCGCCGAGAAGATCGCCGAGAAGCTG
CGGGCCGAAGACCAAATCGACACGGTCTCGATCGCGGGGCCCGGTTTCATCAACCTGACGCTGAAGCCTGCGGTCTGGGC
CGAGGCGCTGCGCGCCGTGCTCGACGCCGGCGCAGGCTACGGCCGCAGCCGGGTCGGCGGGGCCGAGAAGGTCAACATCG
AATACGTCTCCGCCAACCCGACCGGGCCGATGCATGTCGGCCATTGCCGCGGCGCGGTATTCGGCGATGCGCTGGCCAAT
TTGCTCGAGACCGCGGGTTACGACGTCACCCGCGAGTACTACATCAACGACGCCGGCGCGCAGGTCGACGTGCTGGCGCG
TTCGGCATTCCTGCGCTACCGCGAGGCGCTCGGGGAAGACATCGGCGCTATTCCGGAAGGGCTCTATCCGGGCGACTATC
TGGTCCCGGTCGGCACCGCCTTGGTGGCCGAGCACGGCGCCGCGCTGAAAGAACTGCCTGAGCCGCAGTGGCTTCCGATG
GTCCGCGCAAAATCCATCGCGATGATGATGGAGATGATCAAGGCCGATCTCGCCGCGCTCGCGATTACGCACGAAGTGTT
CTTCTCGGAGCGATCTCTGATCGAGGGCGAACGCAACCGTGTCGCCGACACGATCGACTTCCTGCGCGCCAAGGGCGACG
TTTATCAGGGCCGTCTGCCGCCGCCGAAGGGCGCGCCGGTCGAAGACTACGAGGACCGCGAGCAGACGCTGTTCCGAGCC
ACGGCCTATGGCGACGACGTCGACCGGCCGCTGCTGAAGTCTGACGGTACCTATACGTATTTTGCCTCGGACATCGCCTA
TCACAAGGTCAAGTTCGATGCCGGCTTCGGCAACATGGTCGACGTCTGGGGCGCCGATCATGGCGGCTACATCAAGCGGA
TGCAGGCGGCGATCACGGCGGTGACCAGCGGCAAGGGCGCGCTCGACGTCAAGATCGTCCAGCTCGTCCGCCTGTTGCGC
AACGGCGAGCCGGTGAAGATGTCGAAGCGGTCGGGCGATTTCGTCACGCTGCGCGAAGTCGTCGACGAGGTCGGCTCCGA
CGCCGTGCGCTTCATGATGCTGTTCCGCAAGAACGACGCGGTGCTCGACTTCGACCTCGCCAAGGTGATCGAGCAGTCGA
AGGACAATCCCGTTTTCTACGTTCAGTACGGCCATGCCCGCGGCCATTCGATCTTCCGCAACGCCAAGGAGCTGTTCCCG
GACCTGCCGGACGCGACCGAGGCTCGCATCGCCTTCCTGAAAGACGCCAACGCGGAGCGGCTGACCGACCCGTCGGAGCT
GGACCTGCTGCGGCGGCTGGCACTGTTCCCGCGGACCGTAGAAGCCGCTGCGCTGGCCCACGAGCCGCACCGGGTGGCGT
TCTATCTCTATGATCTCGCCAGTGAATTCCACGCGCTCTGGACGCGCGGGCGCGATTTGCCTCATTTACGCTTCATTATC
AATAATGATGCAGAGATTACCAAGGCGCGACTGGCAATGGTTCAGGGCGTCGTCTCGGTTCTGGCTTCAGGGCTTGCCAT
TCTCGGCGTCACTGCGCCGGACGAGATGCGGTAG

Upstream 100 bases:

>100_bases
CGCTTTGACCGAACATCAGCGGCTTTTTGACTCGACCCCGGATTTGCGTTAGGCGGCCCGACCGGCCGGAAATGGCCATC
CCCCAATCAAAACTGCAGCC

Downstream 100 bases:

>100_bases
GGGGACAGCCGATCAGATGGGGATCTGTGGCGGCTTTTGAGAGCAGTTGATCTTCTGCGTGAGCGGGTTTGGCGGCTTTC
CCGAATGGGACGCGACATCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MPDQTTSTHLFAHILARVHAVCAALTDEGALPTGTDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLAEKIAEKL
RAEDQIDTVSIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSRVGGAEKVNIEYVSANPTGPMHVGHCRGAVFGDALAN
LLETAGYDVTREYYINDAGAQVDVLARSAFLRYREALGEDIGAIPEGLYPGDYLVPVGTALVAEHGAALKELPEPQWLPM
VRAKSIAMMMEMIKADLAALAITHEVFFSERSLIEGERNRVADTIDFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRA
TAYGDDVDRPLLKSDGTYTYFASDIAYHKVKFDAGFGNMVDVWGADHGGYIKRMQAAITAVTSGKGALDVKIVQLVRLLR
NGEPVKMSKRSGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAKELFP
DLPDATEARIAFLKDANAERLTDPSELDLLRRLALFPRTVEAAALAHEPHRVAFYLYDLASEFHALWTRGRDLPHLRFII
NNDAEITKARLAMVQGVVSVLASGLAILGVTAPDEMR

Sequences:

>Translated_597_residues
MPDQTTSTHLFAHILARVHAVCAALTDEGALPTGTDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLAEKIAEKL
RAEDQIDTVSIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSRVGGAEKVNIEYVSANPTGPMHVGHCRGAVFGDALAN
LLETAGYDVTREYYINDAGAQVDVLARSAFLRYREALGEDIGAIPEGLYPGDYLVPVGTALVAEHGAALKELPEPQWLPM
VRAKSIAMMMEMIKADLAALAITHEVFFSERSLIEGERNRVADTIDFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRA
TAYGDDVDRPLLKSDGTYTYFASDIAYHKVKFDAGFGNMVDVWGADHGGYIKRMQAAITAVTSGKGALDVKIVQLVRLLR
NGEPVKMSKRSGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAKELFP
DLPDATEARIAFLKDANAERLTDPSELDLLRRLALFPRTVEAAALAHEPHRVAFYLYDLASEFHALWTRGRDLPHLRFII
NNDAEITKARLAMVQGVVSVLASGLAILGVTAPDEMR
>Mature_596_residues
PDQTTSTHLFAHILARVHAVCAALTDEGALPTGTDLSRIVVEPPKDASHGDMATNAAMVLAKDAKAKPRDLAEKIAEKLR
AEDQIDTVSIAGPGFINLTLKPAVWAEALRAVLDAGAGYGRSRVGGAEKVNIEYVSANPTGPMHVGHCRGAVFGDALANL
LETAGYDVTREYYINDAGAQVDVLARSAFLRYREALGEDIGAIPEGLYPGDYLVPVGTALVAEHGAALKELPEPQWLPMV
RAKSIAMMMEMIKADLAALAITHEVFFSERSLIEGERNRVADTIDFLRAKGDVYQGRLPPPKGAPVEDYEDREQTLFRAT
AYGDDVDRPLLKSDGTYTYFASDIAYHKVKFDAGFGNMVDVWGADHGGYIKRMQAAITAVTSGKGALDVKIVQLVRLLRN
GEPVKMSKRSGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAKELFPD
LPDATEARIAFLKDANAERLTDPSELDLLRRLALFPRTVEAAALAHEPHRVAFYLYDLASEFHALWTRGRDLPHLRFIIN
NDAEITKARLAMVQGVVSVLASGLAILGVTAPDEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=659, Percent_Identity=24.5827010622155, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1788184, Length=601, Percent_Identity=25.7903494176373, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71985061, Length=176, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985068, Length=176, Percent_Identity=29.5454545454545, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320548, Length=571, Percent_Identity=26.2697022767075, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI18859963, Length=608, Percent_Identity=22.6973684210526, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RHOP2 (Q2IWF8)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486363.1
- ProteinModelPortal:   Q2IWF8
- STRING:   Q2IWF8
- GeneID:   3910543
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2750
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   RPAL316058:RPB_2750-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65298; Mature: 65167

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQTTSTHLFAHILARVHAVCAALTDEGALPTGTDLSRIVVEPPKDASHGDMATNAAMV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCEEE
LAKDAKAKPRDLAEKIAEKLRAEDQIDTVSIAGPGFINLTLKPAVWAEALRAVLDAGAGY
EECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCC
GRSRVGGAEKVNIEYVSANPTGPMHVGHCRGAVFGDALANLLETAGYDVTREYYINDAGA
CCCCCCCCEEEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
QVDVLARSAFLRYREALGEDIGAIPEGLYPGDYLVPVGTALVAEHGAALKELPEPQWLPM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCCHH
VRAKSIAMMMEMIKADLAALAITHEVFFSERSLIEGERNRVADTIDFLRAKGDVYQGRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
PPKGAPVEDYEDREQTLFRATAYGDDVDRPLLKSDGTYTYFASDIAYHKVKFDAGFGNMV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEECCCEEEEEEEECCCCCCE
DVWGADHGGYIKRMQAAITAVTSGKGALDVKIVQLVRLLRNGEPVKMSKRSGDFVTLREV
EECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHH
VDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAKELFP
HHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCC
DLPDATEARIAFLKDANAERLTDPSELDLLRRLALFPRTVEAAALAHEPHRVAFYLYDLA
CCCCCCHHHEEEEECCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEHHHHHH
SEFHALWTRGRDLPHLRFIINNDAEITKARLAMVQGVVSVLASGLAILGVTAPDEMR
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
PDQTTSTHLFAHILARVHAVCAALTDEGALPTGTDLSRIVVEPPKDASHGDMATNAAMV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCEEE
LAKDAKAKPRDLAEKIAEKLRAEDQIDTVSIAGPGFINLTLKPAVWAEALRAVLDAGAGY
EECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCC
GRSRVGGAEKVNIEYVSANPTGPMHVGHCRGAVFGDALANLLETAGYDVTREYYINDAGA
CCCCCCCCEEEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
QVDVLARSAFLRYREALGEDIGAIPEGLYPGDYLVPVGTALVAEHGAALKELPEPQWLPM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCCCHH
VRAKSIAMMMEMIKADLAALAITHEVFFSERSLIEGERNRVADTIDFLRAKGDVYQGRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
PPKGAPVEDYEDREQTLFRATAYGDDVDRPLLKSDGTYTYFASDIAYHKVKFDAGFGNMV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEECCCEEEEEEEECCCCCCE
DVWGADHGGYIKRMQAAITAVTSGKGALDVKIVQLVRLLRNGEPVKMSKRSGDFVTLREV
EECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHH
VDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNPVFYVQYGHARGHSIFRNAKELFP
HHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCC
DLPDATEARIAFLKDANAERLTDPSELDLLRRLALFPRTVEAAALAHEPHRVAFYLYDLA
CCCCCCHHHEEEEECCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEHHHHHH
SEFHALWTRGRDLPHLRFIINNDAEITKARLAMVQGVVSVLASGLAILGVTAPDEMR
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA