Click here to switch to the map view.

The map label for this gene is ctaA

Identifier: 86749782

GI number: 86749782

Start: 3048239

End: 3049336

Strand: Direct

Name: ctaA

Synonym: RPB_2665

Alternate gene names: 86749782

Gene position: 3048239-3049336 (Clockwise)

Preceding gene: 86749780

Following gene: 86749787

Centisome position: 57.17

GC content: 68.67

Gene sequence:

>1098_bases
ATGACCGCTGCCGCGGAGTCCGAGCGTTTGCGTCCGCCCCGCGTTCGTGCGGTCCGGATCTGGCTGACCGTCGTCGCTGC
ACTGATTGCGGTGATGGTGCTGGTCGGCGGCGCGACGCGTCTGACCGAATCCGGGCTGTCGATCGTCGAATGGAAGCCGG
TCACCGGCACGTTGCCGCCGCTCACCGACGCGCAGTGGCATGCGGCGTTCGAGGGCTACAAGACCATCCCGCAATATCGC
GAACTCAACGCCGGGATGACGCTGTATGAATTCAAGACGATCTTCTGGTGGGAATGGAGCCACCGCCTGCTCGGGCGGGT
GATCGGCATCGCCTATCTGCTGCCGTTCCTGTGGTTCCTGTGGCGTGGCGCGATCGGCCCGCAATGGAAGCGGGCGTTGT
GGGGCATTTTCGCGCTCGGCGCGCTGCAGGGCGCGGTCGGCTGGTGGATGGTGGCGTCGGGACTGTCGCAACGCACCGAA
GTGTCGCAGGTGCGGCTGGCGGTCCATCTGACGCTGGCGCTGATCATCTACGCCGCGATCGTCTGGACACTGCGGCGGCT
CGCGGACAAGCCGCCGATCCCGGCTGCGGCGCGTCTGAAAGTCACCGCGATCGCGTTGCTGGCGCTGACGCTGCTGCAGC
TGTTTCTCGGCGCGCTGGTCGCCGGGCTGCGCGCCGGGCGGGTGTTCAACACCTGGCCGCTGATCGACGGCGCGCTGATC
CCCTCCGCCGAGCGGCTGTGGTTCGAGCAGCCATGGTGGAAGAACCTGTTCGACAATCACCTCACCGTGCAGTTCGACCA
TCGCATGATGGCCTATGCGCTGTGGGCGCTGGCGGCCTGGCACGCGATCGACGCGGTGCGGTCGCGCGCGGGTGGCGCGG
CCTCGGGAGCGCTGTGGCTGTTCGCGGCGCTGTCGCTGCAGGCGGTGCTGGGCATTCTGACGGTGCTGCATGCGACTCCG
ATCGGCCTGGCGTTGGCGCATCAGGCGGTCGGCATCGTCGTGCTGACGCTGGCGGTGCTGCAGGTCGAACGGCTGACGGC
GCCGCGGCTGAAAGCGCTGCCGCGGGCGATGCCGGTGCCGGTCGGTCAGCCGGGCTGA

Upstream 100 bases:

>100_bases
TCATGCTGAAATCACACGCACTTGATACGTACGCGCGACGCCTTGCGCGTGGGGATGGCGCGACTATAAGGGGCGCGAAA
ATCCGTTCAAGGTATGCTTT

Downstream 100 bases:

>100_bases
TCCGCGCCGATATCGCGGCCTCTTCGCCGCTCGACCCAGGCGCTGACCATCGGGGTGAGGAACGCGAGCGGCCAGACGAA
TTTCGGCCAATGCGAGTCGA

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPPLTDAQWHAAFEGYKTIPQYR
ELNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFLWRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTE
VSQVRLAVHLTLALIIYAAIVWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALI
PSAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWLFAALSLQAVLGILTVLHATP
IGLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVPVGQPG

Sequences:

>Translated_365_residues
MTAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPPLTDAQWHAAFEGYKTIPQYR
ELNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFLWRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTE
VSQVRLAVHLTLALIIYAAIVWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALI
PSAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWLFAALSLQAVLGILTVLHATP
IGLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVPVGQPG
>Mature_364_residues
TAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPPLTDAQWHAAFEGYKTIPQYRE
LNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFLWRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTEV
SQVRLAVHLTLALIIYAAIVWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALIP
SAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWLFAALSLQAVLGILTVLHATPI
GLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVPVGQPG

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=335, Percent_Identity=36.7164179104478, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI17921987, Length=266, Percent_Identity=39.4736842105263, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17536069, Length=330, Percent_Identity=38.4848484848485, Blast_Score=191, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6320989, Length=390, Percent_Identity=37.6923076923077, Blast_Score=219, Evalue=6e-58,
Organism=Drosophila melanogaster, GI19922860, Length=341, Percent_Identity=35.7771260997067, Blast_Score=180, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_RHOP2 (Q2IWP3)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486278.1
- STRING:   Q2IWP3
- GeneID:   3910458
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2665
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- ProtClustDB:   CLSK2756834
- BioCyc:   RPAL316058:RPB_2665-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40211; Mature: 40080

Theoretical pI: Translated: 11.41; Mature: 11.41

Prosite motif: NA

Important sites: BINDING 327-327

Signals:

None

Transmembrane regions:

HASH(0x1e6d1d90)-; HASH(0x1e0748e0)-; HASH(0x1df392b0)-; HASH(0x1a3c4820)-; HASH(0x1e63dc0c)-; HASH(0x1e7c46b4)-; HASH(0x1e336920)-; HASH(0x1e7e0dd8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCC
LTDAQWHAAFEGYKTIPQYRELNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFL
CCCCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
WRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTEVSQVRLAVHLTLALIIYAAI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PSAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWL
CCHHHHHCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FAALSLQAVLGILTVLHATPIGLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
VGQPG
CCCCH
>Mature Secondary Structure 
TAAAESERLRPPRVRAVRIWLTVVAALIAVMVLVGGATRLTESGLSIVEWKPVTGTLPP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCC
LTDAQWHAAFEGYKTIPQYRELNAGMTLYEFKTIFWWEWSHRLLGRVIGIAYLLPFLWFL
CCCCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
WRGAIGPQWKRALWGIFALGALQGAVGWWMVASGLSQRTEVSQVRLAVHLTLALIIYAAI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWTLRRLADKPPIPAAARLKVTAIALLALTLLQLFLGALVAGLRAGRVFNTWPLIDGALI
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PSAERLWFEQPWWKNLFDNHLTVQFDHRMMAYALWALAAWHAIDAVRSRAGGAASGALWL
CCHHHHHCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FAALSLQAVLGILTVLHATPIGLALAHQAVGIVVLTLAVLQVERLTAPRLKALPRAMPVP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
VGQPG
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA