Click here to switch to the map view.

The map label for this gene is mcp4 [H]

Identifier: 86749770

GI number: 86749770

Start: 3032049

End: 3034124

Strand: Reverse

Name: mcp4 [H]

Synonym: RPB_2653

Alternate gene names: 86749770

Gene position: 3034124-3032049 (Counterclockwise)

Preceding gene: 86749773

Following gene: 86749763

Centisome position: 56.91

GC content: 66.28

Gene sequence:

>2076_bases
ATGAAGATCGGCCGCCTCTTTGCAATTTCGATGCTTTCGGTGACGGCTCTGGCCATCCTCCCTGCTGCACAGGTCGTGAT
TGAGCAGGTCAGGGCTGTCAACGACAAGGCCGATGCGATCAAGACAGTGGAGGCATTCGGCGCCGTGCTGCTGTTCGCGC
AGGAGGTCGTGAGCCACCGCGCCCCCTACATCGGGCCGCTGTTCCAGGAGCCGGTCGCGACACCCGCGCAGCTCGAGGCG
GTGCGCAAGATCAAGCAGTCGTCCGAAGCCGCCTTCGCCAAGGCGCGCGCGCAGGTCGCGAACGTCTCCGAGACCGAAGC
CATCCGCCGCAGCCTGGAGCAGGCCGCAGCCAAGCTGGCTGACCTTCAAACGTTGGTGGAACCCAGCCTTTCCGCGCCGC
TGAGCGGACGTGATCAAGCCGCGATCAAGAGTTTCCTGCCCGGTATCGCGCAGACCGCCGTGGCGATCGAGCCGATCCTG
AATCGGCTTCAGAACCATGTTGCCAATGCGGATGCATCGCTGACGACCCTGCTCGACGTAGCCCGCACCGCGCAGGATCT
GCGCGTGACGGCGGGCGGACGTGCGGCGTCGCTGTCGCCTGCGCTCAACACCCGGCGCGCGTTGACCGCGGCAGAGAAGG
CAGCGATGGACCGTGCCCAGGGCCGTACCGAGATTGATCGTGACCGTCTGGAGGCCAGCATCGACCAGATCGGCAATCCG
GAGCGTCTGTTGGCCGCATTCAACGACGCCAGGGACACCTACTTTGCGCGCGCGCTTCCGATCGTCGACAAGGAGATCGC
GGCCGGATTGAGCGACCTCAACTATGCGCTCACGGCGGATAAGCTGGCCGACACGGTGGTGCCTGCGGTGCAGAAATTCT
ACTTAGTACGAGATTCGGCCATCGCCGAGGCGCGCAACCGTGCGATCGCCGCGCGTGACCAAGCCTATCTGATGCTATCG
CTGGCGACGGTCGTCGTCGTGGCCTTGTTCGGCATTCTCGTGTTCGTCACCATGCTGCTGCGCCGCCGCGTCATCAACCC
GATCGTGCACCTGACCGGCCTGATCGGCCAGATGGCGGCCGGCAATGACGACGTGGCGATCCCGACCTGCGACCGCGACG
ACGAGATCGCCGCGATGACCGGCTCGCTGCAGACCTTCAAGGAAGCGCTGTTGGAGAAGAAGCGTGCAGAGCAGGCGGCT
GCGGCGGACGCGCAGTCTAAGATCGAGCGGGGCCAGCGGGTGGAGAGGTTCACGCGCGATTTTGAGATGGTGATTGGCGA
GGTCGTTGGCGTCGTTTCATCCGCGTCGGGCGATCTCGAGCGCTCCGCCGCATCCCTGACGACGACGGCGGCCCGCTCGC
TGGAGCTCGCCACCGTGGTGACATCGGCGTCCGAGGAAGCTTCGACCAACGTGCATTCGGTCGCCGCGGCGGCAGAGGAG
ATGAGCTCGTCGGTCAACGAGATAAGCCGTCAGGTGCAGGACTCCGCGCGCATCGCCAGCGAGGCGCTGGCGCAGGCCCG
CAAGACCAACGACAATGTCGCCGAGCTCGCAAAGGCGGCGGCGCGGATCGGCGACGTCGTCGAGCTGATCAATGCGATCG
CGGGGCAAACCAATCTGCTCGCGCTTAACGCCACCATCGAGGCCGCCCGCGCCGGCGAGGCCGGCCGCGGCTTCGCGGTG
GTCGCCTCGGAGGTCAAGGCGCTGGCCGAGCAGACCGCTAAGGCGACCGGAGAGATTGGCCAGCAGATCGGCGGCATCCA
GGCTGCGACCAATGAATCGGTTGGTTCGATCAAGGACATCGGCGAGACCATCGCCCGGATGTCGGAGATCGCCTCCGCCA
TCGCCTCTGCCGTCGAGGAGCAGAGCTCGGCCACGCGCGAAATCTCGAGCAACGTCCAGCAGGCCGCCCACGGCACCCAA
CAGGTCTCGGCGAACATTGCCAGTGTCCGGCAGGGCGCCGACGAGACCGGCTCGGCCTCCTCACAGGTACTGGCGGCCGC
GAAGGCCCTGTCCGGCCAGAGCAGCCGCCTCCGCGACGAGGTCAGCCGCTTCCTGAATTCCGTTCGCGCGGCGTGA

Upstream 100 bases:

>100_bases
CGAGTGAGGCCGCGTCATACGTAAGACTACGGAAGCTGAGCTAAGTATTAACTCAATGGCGGGAACCTAACGTCGTCGCA
ATTAACCTCGGGATTCTACG

Downstream 100 bases:

>100_bases
AGGCCGGCGTCTATCGCGGCATTCTCGCCGAAGCTCGCGGTTATGATCTGCAGAGGCCAATGCCTGGCTGGCCAAATAGG
CGGCTCGGACGAGGTCAGTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MKIGRLFAISMLSVTALAILPAAQVVIEQVRAVNDKADAIKTVEAFGAVLLFAQEVVSHRAPYIGPLFQEPVATPAQLEA
VRKIKQSSEAAFAKARAQVANVSETEAIRRSLEQAAAKLADLQTLVEPSLSAPLSGRDQAAIKSFLPGIAQTAVAIEPIL
NRLQNHVANADASLTTLLDVARTAQDLRVTAGGRAASLSPALNTRRALTAAEKAAMDRAQGRTEIDRDRLEASIDQIGNP
ERLLAAFNDARDTYFARALPIVDKEIAAGLSDLNYALTADKLADTVVPAVQKFYLVRDSAIAEARNRAIAARDQAYLMLS
LATVVVVALFGILVFVTMLLRRRVINPIVHLTGLIGQMAAGNDDVAIPTCDRDDEIAAMTGSLQTFKEALLEKKRAEQAA
AADAQSKIERGQRVERFTRDFEMVIGEVVGVVSSASGDLERSAASLTTTAARSLELATVVTSASEEASTNVHSVAAAAEE
MSSSVNEISRQVQDSARIASEALAQARKTNDNVAELAKAAARIGDVVELINAIAGQTNLLALNATIEAARAGEAGRGFAV
VASEVKALAEQTAKATGEIGQQIGGIQAATNESVGSIKDIGETIARMSEIASAIASAVEEQSSATREISSNVQQAAHGTQ
QVSANIASVRQGADETGSASSQVLAAAKALSGQSSRLRDEVSRFLNSVRAA

Sequences:

>Translated_691_residues
MKIGRLFAISMLSVTALAILPAAQVVIEQVRAVNDKADAIKTVEAFGAVLLFAQEVVSHRAPYIGPLFQEPVATPAQLEA
VRKIKQSSEAAFAKARAQVANVSETEAIRRSLEQAAAKLADLQTLVEPSLSAPLSGRDQAAIKSFLPGIAQTAVAIEPIL
NRLQNHVANADASLTTLLDVARTAQDLRVTAGGRAASLSPALNTRRALTAAEKAAMDRAQGRTEIDRDRLEASIDQIGNP
ERLLAAFNDARDTYFARALPIVDKEIAAGLSDLNYALTADKLADTVVPAVQKFYLVRDSAIAEARNRAIAARDQAYLMLS
LATVVVVALFGILVFVTMLLRRRVINPIVHLTGLIGQMAAGNDDVAIPTCDRDDEIAAMTGSLQTFKEALLEKKRAEQAA
AADAQSKIERGQRVERFTRDFEMVIGEVVGVVSSASGDLERSAASLTTTAARSLELATVVTSASEEASTNVHSVAAAAEE
MSSSVNEISRQVQDSARIASEALAQARKTNDNVAELAKAAARIGDVVELINAIAGQTNLLALNATIEAARAGEAGRGFAV
VASEVKALAEQTAKATGEIGQQIGGIQAATNESVGSIKDIGETIARMSEIASAIASAVEEQSSATREISSNVQQAAHGTQ
QVSANIASVRQGADETGSASSQVLAAAKALSGQSSRLRDEVSRFLNSVRAA
>Mature_691_residues
MKIGRLFAISMLSVTALAILPAAQVVIEQVRAVNDKADAIKTVEAFGAVLLFAQEVVSHRAPYIGPLFQEPVATPAQLEA
VRKIKQSSEAAFAKARAQVANVSETEAIRRSLEQAAAKLADLQTLVEPSLSAPLSGRDQAAIKSFLPGIAQTAVAIEPIL
NRLQNHVANADASLTTLLDVARTAQDLRVTAGGRAASLSPALNTRRALTAAEKAAMDRAQGRTEIDRDRLEASIDQIGNP
ERLLAAFNDARDTYFARALPIVDKEIAAGLSDLNYALTADKLADTVVPAVQKFYLVRDSAIAEARNRAIAARDQAYLMLS
LATVVVVALFGILVFVTMLLRRRVINPIVHLTGLIGQMAAGNDDVAIPTCDRDDEIAAMTGSLQTFKEALLEKKRAEQAA
AADAQSKIERGQRVERFTRDFEMVIGEVVGVVSSASGDLERSAASLTTTAARSLELATVVTSASEEASTNVHSVAAAAEE
MSSSVNEISRQVQDSARIASEALAQARKTNDNVAELAKAAARIGDVVELINAIAGQTNLLALNATIEAARAGEAGRGFAV
VASEVKALAEQTAKATGEIGQQIGGIQAATNESVGSIKDIGETIARMSEIASAIASAVEEQSSATREISSNVQQAAHGTQ
QVSANIASVRQGADETGSASSQVLAAAKALSGQSSRLRDEVSRFLNSVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=329, Percent_Identity=29.7872340425532, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1787690, Length=375, Percent_Identity=27.7333333333333, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI2367378, Length=230, Percent_Identity=34.3478260869565, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=403, Percent_Identity=27.2952853598015, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789453, Length=214, Percent_Identity=32.2429906542056, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72540; Mature: 72540

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGRLFAISMLSVTALAILPAAQVVIEQVRAVNDKADAIKTVEAFGAVLLFAQEVVSHR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCC
APYIGPLFQEPVATPAQLEAVRKIKQSSEAAFAKARAQVANVSETEAIRRSLEQAAAKLA
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLQTLVEPSLSAPLSGRDQAAIKSFLPGIAQTAVAIEPILNRLQNHVANADASLTTLLDV
HHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ARTAQDLRVTAGGRAASLSPALNTRRALTAAEKAAMDRAQGRTEIDRDRLEASIDQIGNP
HHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCH
ERLLAAFNDARDTYFARALPIVDKEIAAGLSDLNYALTADKLADTVVPAVQKFYLVRDSA
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEARNRAIAARDQAYLMLSLATVVVVALFGILVFVTMLLRRRVINPIVHLTGLIGQMAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNDDVAIPTCDRDDEIAAMTGSLQTFKEALLEKKRAEQAAAADAQSKIERGQRVERFTRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEMVIGEVVGVVSSASGDLERSAASLTTTAARSLELATVVTSASEEASTNVHSVAAAAEE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MSSSVNEISRQVQDSARIASEALAQARKTNDNVAELAKAAARIGDVVELINAIAGQTNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQIGGIQAATNESVGSIKDI
EEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GETIARMSEIASAIASAVEEQSSATREISSNVQQAAHGTQQVSANIASVRQGADETGSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
SQVLAAAKALSGQSSRLRDEVSRFLNSVRAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIGRLFAISMLSVTALAILPAAQVVIEQVRAVNDKADAIKTVEAFGAVLLFAQEVVSHR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCC
APYIGPLFQEPVATPAQLEAVRKIKQSSEAAFAKARAQVANVSETEAIRRSLEQAAAKLA
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DLQTLVEPSLSAPLSGRDQAAIKSFLPGIAQTAVAIEPILNRLQNHVANADASLTTLLDV
HHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ARTAQDLRVTAGGRAASLSPALNTRRALTAAEKAAMDRAQGRTEIDRDRLEASIDQIGNP
HHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCH
ERLLAAFNDARDTYFARALPIVDKEIAAGLSDLNYALTADKLADTVVPAVQKFYLVRDSA
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEARNRAIAARDQAYLMLSLATVVVVALFGILVFVTMLLRRRVINPIVHLTGLIGQMAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNDDVAIPTCDRDDEIAAMTGSLQTFKEALLEKKRAEQAAAADAQSKIERGQRVERFTRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEMVIGEVVGVVSSASGDLERSAASLTTTAARSLELATVVTSASEEASTNVHSVAAAAEE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MSSSVNEISRQVQDSARIASEALAQARKTNDNVAELAKAAARIGDVVELINAIAGQTNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQIGGIQAATNESVGSIKDI
EEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GETIARMSEIASAIASAVEEQSSATREISSNVQQAAHGTQQVSANIASVRQGADETGSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
SQVLAAAKALSGQSSRLRDEVSRFLNSVRAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]