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The map label for this gene is bepF [H]

Identifier: 86749686

GI number: 86749686

Start: 2950177

End: 2951415

Strand: Reverse

Name: bepF [H]

Synonym: RPB_2568

Alternate gene names: 86749686

Gene position: 2951415-2950177 (Counterclockwise)

Preceding gene: 86749687

Following gene: 86749685

Centisome position: 55.36

GC content: 67.31

Gene sequence:

>1239_bases
ATGGCTCGGGGACACCTTCCGTCGCTTCCGTCCGCAAGAGGATGGTCGGTCATCGCCGGCCTGTTGTGCGCGCCTTTAGT
CCTGTCGGGATGCAAGGAGCAGAACAAATACGCGGCGCCGCCGCCCACCAAGGTCACCGTCGCCACGCCCACCCGATCGC
CGGTCACGCTCTATGCCGAGTTCACCGGCAACACCGCCCCGGTCGCCTCGGTCGATCTGGAAGCGCGCGTGCAGGGCTTC
CTCGAGAGCATCGACTATCGCGACGGCGAAGCGGTGAAGAAGGGCCGCGTGCTGTTCAAGATCGAACCGGCTCAGTATCA
GGCCCAGGTCGATCTGCAGCAGGCCCAGCTCGACGGCGCCAAGGCCAAGCAGGTCAACGCGCAGCGCGAATACGACCGGC
AGGCCACCCTCGGGCAGAAGGAGGTCGCCACCCAGCGCAATGTCGACGACGCCCAGACCAATCTGGCGTCGGCGAATGCC
CAGGTCGCGGCCAGCGAGGCCTCGCTCAAGCTCGCCAAGACCTCCCTCGCCTATGCCACCGTGACCGCGCCGTTCGACGG
CGTGGTGACGCGCCGCCTCGCCAATATCGGCGCGCTGGTCGGCTCGTCCGGTCCCACCAAGCTCGCCACCATCCTCCAGG
TCGATCCGCTCTACGTCTATTTCAACATCACCGAGCAGCAGCAGATCAATCTGCGCGATGCGCTGGCCAAGCAGGGCAAG
ACCCTGAAGACCATGCGCGAAGACGGGATGGAAATGCCGATCGAGGTCGCGCTGTCGGCCGACACCGCATTCCAATATGC
CGGCAAGGTCGACTACATCGCGCCGCAGGTCGAGACCGCCACCGGGACGCTGCAATTGCGCGGCGTGCTGGAGAACAAGA
ACGTGGCGCTGGTGCCCGGCCTGTTCGTCCGGGTCCGCGTCCCCGTCGGCAAGCTCGACGACGCGCTGCTGGTCGACGAC
ACCGCGGTGATGTCCAACCAGACCGGCAGCTACGTCATGGTGGTCGGCAACAACAACGTCGTCGAGCAGCGCCAGGTGAC
CCCCGGGGCGCTGCAGGGGCAATTGCGTGTGATCACCAAAGGCCTGTCCGCCGACGACAAGGTTGTGATCGGCGCGATCC
AGCGCGCGGTGGCCGGCAACACCGTGGCGCCGGTGTCGGGCGCCATGGCCGCCGCCCCCACCGGCCCCAAGCCGGCCCCC
GCAAGTCTGACGCCCGGAACCGGCGCGTCCAAGCCCTGA

Upstream 100 bases:

>100_bases
CGAAGTTGCGTCAGTCGATGGACCCGTATCTGGGAATCTGATCTGGGTTCCCTGTCGCGCCCGGATATTCGGAGAGGGCG
AGAAAGCGGAGATCCACCTG

Downstream 100 bases:

>100_bases
TCCTTCCGGCCCTCACGAGGCGTCACCATGTTCTCGCGCTTCTTCATCGAACGGCCGGTGCTCTCCAACACGCTGGCGTT
TCTGATCATCCTGTTGGGCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MARGHLPSLPSARGWSVIAGLLCAPLVLSGCKEQNKYAAPPPTKVTVATPTRSPVTLYAEFTGNTAPVASVDLEARVQGF
LESIDYRDGEAVKKGRVLFKIEPAQYQAQVDLQQAQLDGAKAKQVNAQREYDRQATLGQKEVATQRNVDDAQTNLASANA
QVAASEASLKLAKTSLAYATVTAPFDGVVTRRLANIGALVGSSGPTKLATILQVDPLYVYFNITEQQQINLRDALAKQGK
TLKTMREDGMEMPIEVALSADTAFQYAGKVDYIAPQVETATGTLQLRGVLENKNVALVPGLFVRVRVPVGKLDDALLVDD
TAVMSNQTGSYVMVVGNNNVVEQRQVTPGALQGQLRVITKGLSADDKVVIGAIQRAVAGNTVAPVSGAMAAAPTGPKPAP
ASLTPGTGASKP

Sequences:

>Translated_412_residues
MARGHLPSLPSARGWSVIAGLLCAPLVLSGCKEQNKYAAPPPTKVTVATPTRSPVTLYAEFTGNTAPVASVDLEARVQGF
LESIDYRDGEAVKKGRVLFKIEPAQYQAQVDLQQAQLDGAKAKQVNAQREYDRQATLGQKEVATQRNVDDAQTNLASANA
QVAASEASLKLAKTSLAYATVTAPFDGVVTRRLANIGALVGSSGPTKLATILQVDPLYVYFNITEQQQINLRDALAKQGK
TLKTMREDGMEMPIEVALSADTAFQYAGKVDYIAPQVETATGTLQLRGVLENKNVALVPGLFVRVRVPVGKLDDALLVDD
TAVMSNQTGSYVMVVGNNNVVEQRQVTPGALQGQLRVITKGLSADDKVVIGAIQRAVAGNTVAPVSGAMAAAPTGPKPAP
ASLTPGTGASKP
>Mature_411_residues
ARGHLPSLPSARGWSVIAGLLCAPLVLSGCKEQNKYAAPPPTKVTVATPTRSPVTLYAEFTGNTAPVASVDLEARVQGFL
ESIDYRDGEAVKKGRVLFKIEPAQYQAQVDLQQAQLDGAKAKQVNAQREYDRQATLGQKEVATQRNVDDAQTNLASANAQ
VAASEASLKLAKTSLAYATVTAPFDGVVTRRLANIGALVGSSGPTKLATILQVDPLYVYFNITEQQQINLRDALAKQGKT
LKTMREDGMEMPIEVALSADTAFQYAGKVDYIAPQVETATGTLQLRGVLENKNVALVPGLFVRVRVPVGKLDDALLVDDT
AVMSNQTGSYVMVVGNNNVVEQRQVTPGALQGQLRVITKGLSADDKVVIGAIQRAVAGNTVAPVSGAMAAAPTGPKPAPA
SLTPGTGASKP

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=385, Percent_Identity=27.5324675324675, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789665, Length=375, Percent_Identity=27.7333333333333, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786668, Length=372, Percent_Identity=29.8387096774194, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082036, Length=353, Percent_Identity=27.1954674220963, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081796, Length=375, Percent_Identity=25.8666666666667, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43359; Mature: 43228

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGHLPSLPSARGWSVIAGLLCAPLVLSGCKEQNKYAAPPPTKVTVATPTRSPVTLYAE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEE
FTGNTAPVASVDLEARVQGFLESIDYRDGEAVKKGRVLFKIEPAQYQAQVDLQQAQLDGA
ECCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHCCEEEEEECCCCEEEEEEHHHHHCCCC
KAKQVNAQREYDRQATLGQKEVATQRNVDDAQTNLASANAQVAASEASLKLAKTSLAYAT
HHHHCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCEEEECCCCEEEHHHEEEEEE
VTAPFDGVVTRRLANIGALVGSSGPTKLATILQVDPLYVYFNITEQQQINLRDALAKQGK
EECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHHHCCC
TLKTMREDGMEMPIEVALSADTAFQYAGKVDYIAPQVETATGTLQLRGVLENKNVALVPG
HHHHHHHCCCCCCEEEEEECCCHHHHCCCCEEECCCEECCCCEEEEEEEECCCCEEEECC
LFVRVRVPVGKLDDALLVDDTAVMSNQTGSYVMVVGNNNVVEQRQVTPGALQGQLRVITK
EEEEEEECCCCCCCEEEEECHHHHCCCCCCEEEEECCCCEEHHCCCCCHHHCCEEEEEEE
GLSADDKVVIGAIQRAVAGNTVAPVSGAMAAAPTGPKPAPASLTPGTGASKP
CCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARGHLPSLPSARGWSVIAGLLCAPLVLSGCKEQNKYAAPPPTKVTVATPTRSPVTLYAE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEE
FTGNTAPVASVDLEARVQGFLESIDYRDGEAVKKGRVLFKIEPAQYQAQVDLQQAQLDGA
ECCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHCCEEEEEECCCCEEEEEEHHHHHCCCC
KAKQVNAQREYDRQATLGQKEVATQRNVDDAQTNLASANAQVAASEASLKLAKTSLAYAT
HHHHCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCEEEECCCCEEEHHHEEEEEE
VTAPFDGVVTRRLANIGALVGSSGPTKLATILQVDPLYVYFNITEQQQINLRDALAKQGK
EECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCCCCHHHHHHHCCC
TLKTMREDGMEMPIEVALSADTAFQYAGKVDYIAPQVETATGTLQLRGVLENKNVALVPG
HHHHHHHCCCCCCEEEEEECCCHHHHCCCCEEECCCEECCCCEEEEEEEECCCCEEEECC
LFVRVRVPVGKLDDALLVDDTAVMSNQTGSYVMVVGNNNVVEQRQVTPGALQGQLRVITK
EEEEEEECCCCCCCEEEEECHHHHCCCCCCEEEEECCCCEEHHCCCCCHHHCCEEEEEEE
GLSADDKVVIGAIQRAVAGNTVAPVSGAMAAAPTGPKPAPASLTPGTGASKP
CCCCCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]