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The map label for this gene is aprE [H]

Identifier: 86749363

GI number: 86749363

Start: 2572670

End: 2574004

Strand: Direct

Name: aprE [H]

Synonym: RPB_2243

Alternate gene names: 86749363

Gene position: 2572670-2574004 (Clockwise)

Preceding gene: 86749362

Following gene: 86749364

Centisome position: 48.25

GC content: 64.79

Gene sequence:

>1335_bases
ATGGCGCAAACCGATTTCGCCTTTTCCAACGACGTCCGCGCAGCCGTCGAGCTACGCACGCCGAAAACGGCGCGGATGTT
GCTGTCTGCATCTTTGGCGCTGTTCTTCACCTTCTTGGCCTGGGCGCATTTCGCCGTGCTCGACGAGGTCAAGCGCGGCA
ACGGCAAGGTGGTGCCGTCGCGGCAAACCCAAGTGGTCCAGTCGCTCGAAGGCGGCATCATCGCCGAACTGCTGGTTCAA
GAAGGTGCGATCGTCGACAAGGATCAGCCGCTGGCGCGCATCGAGGACACCAACTTCGCGGCACAGTTCGGCGAGATCCG
CGAACGTCGTGGCGCGATGGGGGCGCGTGTCCTGCGGCTCGAGGCCGAGACCGAGGGCCGCGCCAGCGTCGTGTTTCCCG
CCGAACTGATGCAGGTCGCGCCGCGCGCGGTCGAAGCCGAGCGTCTGGTGTTCGAGGCGCACAACCGCAAGTTGGCGCAG
GATATCGACGTCGTCCAGCAGCAGGAGATCCAGAAGACCAAGGAGATCGACGAGCTGCGCGCCAGCGAGAAACGCTTCTC
CGAGACGCTGACCCTGCTCAACCGCGAGATCGCGCTGACCCGCAAGCTCTACGATCAGAAGGTGGTGCCGGAGATCGAGA
TGCTGCGAGCCGATCGGCAGGCCACCGACATGCGCGGCCAACTCGCGGTGGTGCAGGCGACCATCATCAAGACCCAGGCG
GCGGTTCAGGAGGCGCGGTCGCGCCGGCTCAACATCACCACGGCGTTCCGCGCCCAGGCCGAGGACGATCTCGCCAAATC
CCGCGGCGATCTCGCCGTGCTGGACGAGAACATCAAGTCGGCGAAGGATCGCGTCCGCCGCACCGAGCTGCGCTCGCCGG
TGCATGGCGTCGTCAACAAGCTGAATATCACCACGATCGGTGCCGTCGTCGCCCCCGGCGCGAGTCTGATGGAAATCGTG
CCGCTCGACGACACGCTGCTGGTCGAAGGCCGCATCCGCCCGCAGGACATCGCCTTCATTCGCCCCGATCACGAGGCGGT
GGTGAAGCTGAGCGCCTACGATTCATCGGTCTACGGATCGCTGCACGGCCGCGTCGAGCGGATCAGCGCCGACACCATCA
CCGACGAAAAGGGTGACAAGAACGAGCGCGGCGAGACGTTTTACCGGGTGATGGTGCGGACCGAGAAGAACCATCTCGGC
ACCAATGAACAGCCGCTGCCGATCATTCCGGGCATGGTGGCCACGGTCGAGATTCTCACCGGCAAGAAGTCGGTGCTGGA
CTATCTGATCAAGCCGGCGCGCACCCTGCGAGACGAAGCGCTCCGCGAACGCTGA

Upstream 100 bases:

>100_bases
AAGATCGTCGCCGACGGACCGACCGAGCAGATCTTGACGAAGCTGCGTCCGCAACCGGCCGCGGCTCCGGCCGCTGCCGG
GCGAATCTGAGGGCGAAAAA

Downstream 100 bases:

>100_bases
GGCAGCGCAGGCGGCGACGGCATCGTCAACAAATCCTGAATCGGTAAAATTCGACGCGATCGGGTGGTACGCGATTAGTT
GCGTTCCCAACTCGGCGCAA

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAQTDFAFSNDVRAAVELRTPKTARMLLSASLALFFTFLAWAHFAVLDEVKRGNGKVVPSRQTQVVQSLEGGIIAELLVQ
EGAIVDKDQPLARIEDTNFAAQFGEIRERRGAMGARVLRLEAETEGRASVVFPAELMQVAPRAVEAERLVFEAHNRKLAQ
DIDVVQQQEIQKTKEIDELRASEKRFSETLTLLNREIALTRKLYDQKVVPEIEMLRADRQATDMRGQLAVVQATIIKTQA
AVQEARSRRLNITTAFRAQAEDDLAKSRGDLAVLDENIKSAKDRVRRTELRSPVHGVVNKLNITTIGAVVAPGASLMEIV
PLDDTLLVEGRIRPQDIAFIRPDHEAVVKLSAYDSSVYGSLHGRVERISADTITDEKGDKNERGETFYRVMVRTEKNHLG
TNEQPLPIIPGMVATVEILTGKKSVLDYLIKPARTLRDEALRER

Sequences:

>Translated_444_residues
MAQTDFAFSNDVRAAVELRTPKTARMLLSASLALFFTFLAWAHFAVLDEVKRGNGKVVPSRQTQVVQSLEGGIIAELLVQ
EGAIVDKDQPLARIEDTNFAAQFGEIRERRGAMGARVLRLEAETEGRASVVFPAELMQVAPRAVEAERLVFEAHNRKLAQ
DIDVVQQQEIQKTKEIDELRASEKRFSETLTLLNREIALTRKLYDQKVVPEIEMLRADRQATDMRGQLAVVQATIIKTQA
AVQEARSRRLNITTAFRAQAEDDLAKSRGDLAVLDENIKSAKDRVRRTELRSPVHGVVNKLNITTIGAVVAPGASLMEIV
PLDDTLLVEGRIRPQDIAFIRPDHEAVVKLSAYDSSVYGSLHGRVERISADTITDEKGDKNERGETFYRVMVRTEKNHLG
TNEQPLPIIPGMVATVEILTGKKSVLDYLIKPARTLRDEALRER
>Mature_443_residues
AQTDFAFSNDVRAAVELRTPKTARMLLSASLALFFTFLAWAHFAVLDEVKRGNGKVVPSRQTQVVQSLEGGIIAELLVQE
GAIVDKDQPLARIEDTNFAAQFGEIRERRGAMGARVLRLEAETEGRASVVFPAELMQVAPRAVEAERLVFEAHNRKLAQD
IDVVQQQEIQKTKEIDELRASEKRFSETLTLLNREIALTRKLYDQKVVPEIEMLRADRQATDMRGQLAVVQATIIKTQAA
VQEARSRRLNITTAFRAQAEDDLAKSRGDLAVLDENIKSAKDRVRRTELRSPVHGVVNKLNITTIGAVVAPGASLMEIVP
LDDTLLVEGRIRPQDIAFIRPDHEAVVKLSAYDSSVYGSLHGRVERISADTITDEKGDKNERGETFYRVMVRTEKNHLGT
NEQPLPIIPGMVATVEILTGKKSVLDYLIKPARTLRDEALRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49575; Mature: 49444

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTDFAFSNDVRAAVELRTPKTARMLLSASLALFFTFLAWAHFAVLDEVKRGNGKVVPS
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RQTQVVQSLEGGIIAELLVQEGAIVDKDQPLARIEDTNFAAQFGEIRERRGAMGARVLRL
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEEE
EAETEGRASVVFPAELMQVAPRAVEAERLVFEAHNRKLAQDIDVVQQQEIQKTKEIDELR
EECCCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ASEKRFSETLTLLNREIALTRKLYDQKVVPEIEMLRADRQATDMRGQLAVVQATIIKTQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
AVQEARSRRLNITTAFRAQAEDDLAKSRGDLAVLDENIKSAKDRVRRTELRSPVHGVVNK
HHHHHHHCEEEEEEHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHH
LNITTIGAVVAPGASLMEIVPLDDTLLVEGRIRPQDIAFIRPDHEAVVKLSAYDSSVYGS
CCCEEEHHHHCCCCCCEEEECCCCEEEEECCCCCCCEEEECCCHHHEEEEEECCCHHHHH
LHGRVERISADTITDEKGDKNERGETFYRVMVRTEKNHLGTNEQPLPIIPGMVATVEILT
HHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHC
GKKSVLDYLIKPARTLRDEALRER
CHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQTDFAFSNDVRAAVELRTPKTARMLLSASLALFFTFLAWAHFAVLDEVKRGNGKVVPS
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RQTQVVQSLEGGIIAELLVQEGAIVDKDQPLARIEDTNFAAQFGEIRERRGAMGARVLRL
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEEE
EAETEGRASVVFPAELMQVAPRAVEAERLVFEAHNRKLAQDIDVVQQQEIQKTKEIDELR
EECCCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ASEKRFSETLTLLNREIALTRKLYDQKVVPEIEMLRADRQATDMRGQLAVVQATIIKTQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHHH
AVQEARSRRLNITTAFRAQAEDDLAKSRGDLAVLDENIKSAKDRVRRTELRSPVHGVVNK
HHHHHHHCEEEEEEHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHH
LNITTIGAVVAPGASLMEIVPLDDTLLVEGRIRPQDIAFIRPDHEAVVKLSAYDSSVYGS
CCCEEEHHHHCCCCCCEEEECCCCEEEEECCCCCCCEEEECCCHHHEEEEEECCCHHHHH
LHGRVERISADTITDEKGDKNERGETFYRVMVRTEKNHLGTNEQPLPIIPGMVATVEILT
HHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHC
GKKSVLDYLIKPARTLRDEALRER
CHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]