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The map label for this gene is 86749283

Identifier: 86749283

GI number: 86749283

Start: 2453392

End: 2454810

Strand: Direct

Name: 86749283

Synonym: RPB_2162

Alternate gene names: NA

Gene position: 2453392-2454810 (Clockwise)

Preceding gene: 86749282

Following gene: 86749285

Centisome position: 46.02

GC content: 69.77

Gene sequence:

>1419_bases
ATGGAACGGGCAGTGCGGCTGCTGCTGGCGCTTTTCATGATGGCGTCGTGTTCGGCGGCCTGGGCCGAGACCCGGGTTGC
GCTGGTCGTCGGCAATTCTGCCTATCGTCACGTCACCGCCCTCGACAATCCGATCAAGGACGCCGCTCTGATGGTCGAGA
CGTTGAGGCGTCTCGGCTTCAGGCTTGTCGGTGGCGGCGCGCAGCTCGACGTCGACAAGGCGCGGTTCGACACGCTGGTG
CAGCAGTTCGGCCGCGACGCCGCCGGCGCCGATGTCGGGCTGTTCTACTATGCGGGCCATGGCGTGCAGATTCGTGGCGT
CAATTATCTGGTGCCGGTCGGCGCCAACCCGACGCGCGAGGCCGACGTCGATTTCCAGATGCTCGATGTCGGGCTGGTGC
TGCGGCAGATGGAGAGTGCCGGCACGCGGCTCAACATCGTCCTGCTCGACGCCTGCCGCAACAACCCGTTCGGTGGTCGG
GGGCTGCGCGCCGCCGGCGGCGGTTTGGCGCAGATGCAGGCGCCCGAGGGCACGCTGATTTCTTACGCGACCCAGCCCGG
CAACGTCGCCCAGGACGGCGACGACGGCCACAGTCCCTATACGCGGGCCCTGGCCGAGATCATGACGCGGCCGGGGCTCG
ACATCTTTCAGACCTTCAACCGCGTCGGGTTGGCCGTGAAAAAGGCGACCGCCAGCGCTCAGCAGCCGTGGCTGTCGTCG
TCGCCGATCCAGGGCGACTTCTATTTCTCCGGCCAGGCTGCCGCTGCGGCCGCCGCGCCGACGTCTCCTCAGACAGCCGC
GGTCGCGCCGCCGGAGTCACCCGGGCTTTCACCCGCGAGGCCGGCCGAGCCGGTCACGGCGCCGAATCCGTCGCCCTCGA
TCTCGTCGTCGCCGCCGCCGCGCCGGGGTTTCCGCGTGCTCGATAGCGTCTCCGAAGGCATCCTCAACATGCGCTCCGGG
CCCGGCACGGGTCATCCGATCGTGGTTGCGATTCCGGCTGGCAGCACGGGCGACTCCAAGGGGAACTGCCGTGCGCCGGA
TGATGGCGGCCGCCATCCTTGGTGCGAGGTCGAATGGCGCGGCCGCACCGGCTGGGTCTCGAGCCGATCGATCGTCGAGA
CACGCCGCGACGAGGCCGCACCGCCTCAAGCAAAGTCGCGTGCGCGGCCTGTGTTCCGCGTGCTCGGCAGCGTGTCGCAA
GGCATCCTCTATGTGCGCGCCGGCCCGGGCACGGGTCACCCGGCCTTGTTCTCCATTCCGGCCGGTGCGTCCGGCATCCA
GCTCGGGCGCTGCCGCAGCTCCGAAGACGGTGTGGGCGCGCCGTGGTGCGAGGTCGAATGGGGCGGGCGCGCCGGCTGGG
CCTCGGCCTGCTGCATGGTCGATGCCGCGACCGGCGCCTTCGCAACGGTGCGGGATTGA

Upstream 100 bases:

>100_bases
GAAGTTCGGCCACGCCGCATCAAAGGCGGCGTGAGCGGGCATTGGCGGCCCGGCCCTGTTCGGTCTATCGTCGCACCGGC
GGTGAGGAGAGATCGCGGCG

Downstream 100 bases:

>100_bases
TCGGCGGTGCGGGATTGATCGGCGCGGATCGGCTGATCGCAGATCGGTCGCGCACGGACGAAGCGCGATCCGATCAATCC
TGCTGCGCGCGTCGGCGAAA

Product: peptidase C14, caspase catalytic subunit p20

Products: NA

Alternate protein names: Caspase Domain Protein; Caspase-Like Domain- And TPR Repeat-Containing Peptidase; Peptidase C; Caspase-Like Domain-Containing Protein; Peptidase Protein; Caspase Domain-Containing Protein; TPR Repeat-Containing Caspace; GUN4-Like Family; Caspase; Peptidylprolyl Isomerase; Caspase-1 P; ICE-Like Protease

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MERAVRLLLALFMMASCSAAWAETRVALVVGNSAYRHVTALDNPIKDAALMVETLRRLGFRLVGGGAQLDVDKARFDTLV
QQFGRDAAGADVGLFYYAGHGVQIRGVNYLVPVGANPTREADVDFQMLDVGLVLRQMESAGTRLNIVLLDACRNNPFGGR
GLRAAGGGLAQMQAPEGTLISYATQPGNVAQDGDDGHSPYTRALAEIMTRPGLDIFQTFNRVGLAVKKATASAQQPWLSS
SPIQGDFYFSGQAAAAAAAPTSPQTAAVAPPESPGLSPARPAEPVTAPNPSPSISSSPPPRRGFRVLDSVSEGILNMRSG
PGTGHPIVVAIPAGSTGDSKGNCRAPDDGGRHPWCEVEWRGRTGWVSSRSIVETRRDEAAPPQAKSRARPVFRVLGSVSQ
GILYVRAGPGTGHPALFSIPAGASGIQLGRCRSSEDGVGAPWCEVEWGGRAGWASACCMVDAATGAFATVRD

Sequences:

>Translated_472_residues
MERAVRLLLALFMMASCSAAWAETRVALVVGNSAYRHVTALDNPIKDAALMVETLRRLGFRLVGGGAQLDVDKARFDTLV
QQFGRDAAGADVGLFYYAGHGVQIRGVNYLVPVGANPTREADVDFQMLDVGLVLRQMESAGTRLNIVLLDACRNNPFGGR
GLRAAGGGLAQMQAPEGTLISYATQPGNVAQDGDDGHSPYTRALAEIMTRPGLDIFQTFNRVGLAVKKATASAQQPWLSS
SPIQGDFYFSGQAAAAAAAPTSPQTAAVAPPESPGLSPARPAEPVTAPNPSPSISSSPPPRRGFRVLDSVSEGILNMRSG
PGTGHPIVVAIPAGSTGDSKGNCRAPDDGGRHPWCEVEWRGRTGWVSSRSIVETRRDEAAPPQAKSRARPVFRVLGSVSQ
GILYVRAGPGTGHPALFSIPAGASGIQLGRCRSSEDGVGAPWCEVEWGGRAGWASACCMVDAATGAFATVRD
>Mature_472_residues
MERAVRLLLALFMMASCSAAWAETRVALVVGNSAYRHVTALDNPIKDAALMVETLRRLGFRLVGGGAQLDVDKARFDTLV
QQFGRDAAGADVGLFYYAGHGVQIRGVNYLVPVGANPTREADVDFQMLDVGLVLRQMESAGTRLNIVLLDACRNNPFGGR
GLRAAGGGLAQMQAPEGTLISYATQPGNVAQDGDDGHSPYTRALAEIMTRPGLDIFQTFNRVGLAVKKATASAQQPWLSS
SPIQGDFYFSGQAAAAAAAPTSPQTAAVAPPESPGLSPARPAEPVTAPNPSPSISSSPPPRRGFRVLDSVSEGILNMRSG
PGTGHPIVVAIPAGSTGDSKGNCRAPDDGGRHPWCEVEWRGRTGWVSSRSIVETRRDEAAPPQAKSRARPVFRVLGSVSQ
GILYVRAGPGTGHPALFSIPAGASGIQLGRCRSSEDGVGAPWCEVEWGGRAGWASACCMVDAATGAFATVRD

Specific function: Unknown

COG id: COG4249

COG function: function code R; Uncharacterized protein containing caspase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5803078, Length=134, Percent_Identity=35.8208955223881, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI27886566, Length=134, Percent_Identity=35.8208955223881, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49440; Mature: 49440

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50208 CASPASE_P20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERAVRLLLALFMMASCSAAWAETRVALVVGNSAYRHVTALDNPIKDAALMVETLRRLGF
CHHHHHHHHHHHHHHHCHHHHHHCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCE
RLVGGGAQLDVDKARFDTLVQQFGRDAAGADVGLFYYAGHGVQIRGVNYLVPVGANPTRE
EEECCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCEEEEECCCCCCCC
ADVDFQMLDVGLVLRQMESAGTRLNIVLLDACRNNPFGGRGLRAAGGGLAQMQAPEGTLI
CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEE
SYATQPGNVAQDGDDGHSPYTRALAEIMTRPGLDIFQTFNRVGLAVKKATASAQQPWLSS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPIQGDFYFSGQAAAAAAAPTSPQTAAVAPPESPGLSPARPAEPVTAPNPSPSISSSPPP
CCCCCEEEECCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RRGFRVLDSVSEGILNMRSGPGTGHPIVVAIPAGSTGDSKGNCRAPDDGGRHPWCEVEWR
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEC
GRTGWVSSRSIVETRRDEAAPPQAKSRARPVFRVLGSVSQGILYVRAGPGTGHPALFSIP
CCCCCCCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCEEEECC
AGASGIQLGRCRSSEDGVGAPWCEVEWGGRAGWASACCMVDAATGAFATVRD
CCCCCCEECCCCCCCCCCCCCEEEEEECCCCCHHHHEEEEECCCCCEEECCC
>Mature Secondary Structure
MERAVRLLLALFMMASCSAAWAETRVALVVGNSAYRHVTALDNPIKDAALMVETLRRLGF
CHHHHHHHHHHHHHHHCHHHHHHCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCE
RLVGGGAQLDVDKARFDTLVQQFGRDAAGADVGLFYYAGHGVQIRGVNYLVPVGANPTRE
EEECCCCEECHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCEEEEECCCCCCCC
ADVDFQMLDVGLVLRQMESAGTRLNIVLLDACRNNPFGGRGLRAAGGGLAQMQAPEGTLI
CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEE
SYATQPGNVAQDGDDGHSPYTRALAEIMTRPGLDIFQTFNRVGLAVKKATASAQQPWLSS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPIQGDFYFSGQAAAAAAAPTSPQTAAVAPPESPGLSPARPAEPVTAPNPSPSISSSPPP
CCCCCEEEECCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RRGFRVLDSVSEGILNMRSGPGTGHPIVVAIPAGSTGDSKGNCRAPDDGGRHPWCEVEWR
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEC
GRTGWVSSRSIVETRRDEAAPPQAKSRARPVFRVLGSVSQGILYVRAGPGTGHPALFSIP
CCCCCCCCCHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCEEEECC
AGASGIQLGRCRSSEDGVGAPWCEVEWGGRAGWASACCMVDAATGAFATVRD
CCCCCCEECCCCCCCCCCCCCEEEEEECCCCCHHHHEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA