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The map label for this gene is yngJ [H]

Identifier: 86748873

GI number: 86748873

Start: 2000372

End: 2001514

Strand: Direct

Name: yngJ [H]

Synonym: RPB_1750

Alternate gene names: 86748873

Gene position: 2000372-2001514 (Clockwise)

Preceding gene: 86748872

Following gene: 86748874

Centisome position: 37.52

GC content: 66.23

Gene sequence:

>1143_bases
ATGGATTTTGATTTGTCGGAAGAGCAGCGGCTGCTCAAGGAAAGCGTCGAGGGTCTGTTGAAATCCTCGTACGATTTCGA
CAGCCGCAAGAAATACGCCAAGGAAAAAGACGGCTGGAGCCGCGACGTCTGGGGCAAGTTTGCCGAGCAGGGCCTGCTCG
GCCTGCCGTTCTCGGAAGAAGACGGCGGCTTCGGCGCCGGCGCGGTCGAGACCATGATCGTGATGGAAGCGCTCGGCCAT
TCGCTGGTGCTCGAGCCGTATCTGCCGACCGTGATCATCGCCGGCGGCTTCCTGCGCCGCGCCGGCTCGGCCGCGCAGAA
GGCCGCGCATCTGCCGGGCATCATCGACGGCAGCAAGACCTTCGCGTTCGCCCAGCTCGAGAAGAATTCGCGCTGGGATC
TCGGCGACGTCTCCACCACTGCCAAGAAGAAGGGCGACGGCTGGATCCTCGACGGCGAGAAGTTCGTGGTGCTGAACGGC
GAGGCCGCCGACACGCTGGTGGTCACCGCGCGCACCGCGGGCGGCCAGCGTGACCGCAACGGCGTCGGCGTGTTTCTGGT
GCCGGCCGACGCCAAGGGCGTGTCGCGCAAGGGCTACCCGACCCAGGACGGCCAGCGCGCCGCCGACATCACCTTCACCG
GCGTCGAGATCGGCGCGGATGCAGTGATCGGCGATCCGGCCAACGGCCTGCCGCTGATCGAGCAGGTGGTCGACGACGCC
CGCTCGGCGCTGTGCGCGGAGGCGGTCGGCGCGATGGATGAATCGCTCACCACCACGGTCGAGTACATCAAGACCCGCAA
GCAGTTCGGCGTGCCGATCGGCAGCTTCCAGGTGCTGCAGCATCGCGCCGCCGACATGTTCGTCGCCGCCGAACAGGCCC
GCTCGATGGCGATGTTCGCCACCATGGCGGCGGATTTCGACGACGCGAAAGAGCGTGCCAACGCCATCGCGGCGGCCAAG
GTGCAGATCGGCAAGTCGGCCAAGTTCGTCGGCCAGCAGTCGATCCAGCTGCACGGCGGCATCGGCATGACGATGGAAGC
CAAGATCGGCCACTACTTCAAGCGGCTGACCATGATCGAACAGACCTTCGGCGACACCGACCACCACTTGGCGCGCGTCA
GCGAAGCCGGCGGGCTGATCTGA

Upstream 100 bases:

>100_bases
CGAGAGTCAGCGACGCGTGTCGCCCCTCACCCCAACCCTCTCCCCGCAAGAGCGGGGCGAGGGAGCACGCCAACCGAATT
TCTGAAGGAAAGCCATCACC

Downstream 100 bases:

>100_bases
GCCTCTCAACGAGTCATTCCGGGGCGCTCACGCAGTGAGCGAACCCGGAATCTCTGTTTCCAAGAACCGCGAGATTCCGG
GGAGCGCGCCTGCGGCGCGC

Product: Acyl-CoA dehydrogenase-like

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFDLSEEQRLLKESVEGLLKSSYDFDSRKKYAKEKDGWSRDVWGKFAEQGLLGLPFSEEDGGFGAGAVETMIVMEALGH
SLVLEPYLPTVIIAGGFLRRAGSAAQKAAHLPGIIDGSKTFAFAQLEKNSRWDLGDVSTTAKKKGDGWILDGEKFVVLNG
EAADTLVVTARTAGGQRDRNGVGVFLVPADAKGVSRKGYPTQDGQRAADITFTGVEIGADAVIGDPANGLPLIEQVVDDA
RSALCAEAVGAMDESLTTTVEYIKTRKQFGVPIGSFQVLQHRAADMFVAAEQARSMAMFATMAADFDDAKERANAIAAAK
VQIGKSAKFVGQQSIQLHGGIGMTMEAKIGHYFKRLTMIEQTFGDTDHHLARVSEAGGLI

Sequences:

>Translated_380_residues
MDFDLSEEQRLLKESVEGLLKSSYDFDSRKKYAKEKDGWSRDVWGKFAEQGLLGLPFSEEDGGFGAGAVETMIVMEALGH
SLVLEPYLPTVIIAGGFLRRAGSAAQKAAHLPGIIDGSKTFAFAQLEKNSRWDLGDVSTTAKKKGDGWILDGEKFVVLNG
EAADTLVVTARTAGGQRDRNGVGVFLVPADAKGVSRKGYPTQDGQRAADITFTGVEIGADAVIGDPANGLPLIEQVVDDA
RSALCAEAVGAMDESLTTTVEYIKTRKQFGVPIGSFQVLQHRAADMFVAAEQARSMAMFATMAADFDDAKERANAIAAAK
VQIGKSAKFVGQQSIQLHGGIGMTMEAKIGHYFKRLTMIEQTFGDTDHHLARVSEAGGLI
>Mature_380_residues
MDFDLSEEQRLLKESVEGLLKSSYDFDSRKKYAKEKDGWSRDVWGKFAEQGLLGLPFSEEDGGFGAGAVETMIVMEALGH
SLVLEPYLPTVIIAGGFLRRAGSAAQKAAHLPGIIDGSKTFAFAQLEKNSRWDLGDVSTTAKKKGDGWILDGEKFVVLNG
EAADTLVVTARTAGGQRDRNGVGVFLVPADAKGVSRKGYPTQDGQRAADITFTGVEIGADAVIGDPANGLPLIEQVVDDA
RSALCAEAVGAMDESLTTTVEYIKTRKQFGVPIGSFQVLQHRAADMFVAAEQARSMAMFATMAADFDDAKERANAIAAAK
VQIGKSAKFVGQQSIQLHGGIGMTMEAKIGHYFKRLTMIEQTFGDTDHHLARVSEAGGLI

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=391, Percent_Identity=28.6445012787724, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=27.5401069518717, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI226958414, Length=333, Percent_Identity=27.6276276276276, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4501857, Length=319, Percent_Identity=29.153605015674, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7656849, Length=362, Percent_Identity=25.1381215469613, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4501859, Length=366, Percent_Identity=26.2295081967213, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI76496475, Length=382, Percent_Identity=26.1780104712042, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4557235, Length=382, Percent_Identity=26.1780104712042, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=25.0666666666667, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=25.0666666666667, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI21361497, Length=342, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=22.976501305483, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786223, Length=364, Percent_Identity=24.4505494505494, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=28.1081081081081, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=27.3480662983425, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570075, Length=401, Percent_Identity=25.9351620947631, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=26.1707988980716, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=25.7978723404255, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=347, Percent_Identity=26.8011527377522, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=326, Percent_Identity=24.5398773006135, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=353, Percent_Identity=22.9461756373938, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=260, Percent_Identity=25.3846153846154, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=323, Percent_Identity=24.4582043343653, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=26.7326732673267, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=24.6719160104987, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=27.6363636363636, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21355753, Length=326, Percent_Identity=27.9141104294479, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=27.9005524861878, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=24.5901639344262, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=25.1336898395722, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=23.4375, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363737, Length=385, Percent_Identity=24.6753246753247, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 40685; Mature: 40685

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDLSEEQRLLKESVEGLLKSSYDFDSRKKYAKEKDGWSRDVWGKFAEQGLLGLPFSEE
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCC
DGGFGAGAVETMIVMEALGHSLVLEPYLPTVIIAGGFLRRAGSAAQKAAHLPGIIDGSKT
CCCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHCHHHHHCCHHHHHHHCCCCEECCCCE
FAFAQLEKNSRWDLGDVSTTAKKKGDGWILDGEKFVVLNGEAADTLVVTARTAGGQRDRN
EEEEEECCCCCCCCCCCCHHHHCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCCCCC
GVGVFLVPADAKGVSRKGYPTQDGQRAADITFTGVEIGADAVIGDPANGLPLIEQVVDDA
CCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECEEECCCEEECCCCCCCHHHHHHHHHH
RSALCAEAVGAMDESLTTTVEYIKTRKQFGVPIGSFQVLQHRAADMFVAAEQARSMAMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMAADFDDAKERANAIAAAKVQIGKSAKFVGQQSIQLHGGIGMTMEAKIGHYFKRLTMIE
HHHCCHHHHHHHHHHHHHEEEEECCCHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHHHH
QTFGDTDHHLARVSEAGGLI
HHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MDFDLSEEQRLLKESVEGLLKSSYDFDSRKKYAKEKDGWSRDVWGKFAEQGLLGLPFSEE
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCC
DGGFGAGAVETMIVMEALGHSLVLEPYLPTVIIAGGFLRRAGSAAQKAAHLPGIIDGSKT
CCCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHCHHHHHCCHHHHHHHCCCCEECCCCE
FAFAQLEKNSRWDLGDVSTTAKKKGDGWILDGEKFVVLNGEAADTLVVTARTAGGQRDRN
EEEEEECCCCCCCCCCCCHHHHCCCCCEEECCCEEEEEECCCCCEEEEEEECCCCCCCCC
GVGVFLVPADAKGVSRKGYPTQDGQRAADITFTGVEIGADAVIGDPANGLPLIEQVVDDA
CCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECEEECCCEEECCCCCCCHHHHHHHHHH
RSALCAEAVGAMDESLTTTVEYIKTRKQFGVPIGSFQVLQHRAADMFVAAEQARSMAMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMAADFDDAKERANAIAAAKVQIGKSAKFVGQQSIQLHGGIGMTMEAKIGHYFKRLTMIE
HHHCCHHHHHHHHHHHHHEEEEECCCHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHHHH
QTFGDTDHHLARVSEAGGLI
HHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]