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The map label for this gene is mcp4 [H]

Identifier: 86748839

GI number: 86748839

Start: 1954679

End: 1956373

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1716

Alternate gene names: 86748839

Gene position: 1954679-1956373 (Clockwise)

Preceding gene: 86748838

Following gene: 86748840

Centisome position: 36.66

GC content: 67.08

Gene sequence:

>1695_bases
ATGGGACGTGGGATCGCTAATATCGGCCTTTCATGGAAGGTCCAGCTCGCTCCGGCACTGCTCGCGATTGCGCTGATAGG
TATCGGGGTCTACGCGTTGCAGGCGTTGCGCACCAATCAGCAAAGCGTCGACGCGCTGGTATCGGGTCCCGTTCGGTCGT
CGGAACTCGCCGCCGACCTCAACAACGCCGCGTGGACCGCCCACGCGAAGCTCTATCGGCTCGCCGCCACCGCCGCCAAC
GAGACCGACGAAGCCAAGCTCGCCCAGGTCTCCAAAGAGGCGATCGCGGCTATCGCCCGAATTCCGCAAGCCCTGGCAGA
CGTCGAAAAATCGCTCGGCGGCGACTCGGCGATCCAAAAGCTGAAAGCGGCGGTCGCGGGCTACCAGAAGCAGGCGAAGA
ACGCGATCGAGATGGCCGACGGCGACGCCGGCTCGGCGCTGCTGTTCATCAAGAGCGCGGAGAAGAGCTTCACCGAAATC
GATGCCCTCATCAGCGACCTGATCGTGTCCAGCAACGACGCGCGTGACCGGCAGATCGCGCAGGCCGGAATCGCGCTGGA
TCGCCAGCAGTGGATGCTCGGCGCCGTCCTGGCGGTGATTTCGCTGATCGGCATCGCCGTGTCGTTCCTGATCGGCAGAG
GCATCGCTCGTCCGGTGGTGGCGATGTCGGGCGCAATGCATGAACTGGCGAGCGGCAATTTCGACGTGCGACTGCCCGGG
CTGGAACGTGGCGACGAGGTCGGCCGGATGGCGCGGGCCGTCGAAGCCTTCAAGGTTCAGGCGGCCAGCAAGGCGGAGCG
CGAACACGCCGAGCGCGAGGCGCTGGAACGCACGGCGGCGGCCGCCCGCCGCGCCGAACTGCATCAGCTCGCCGACGGTT
TCGAGACCGCGGTCGGCCAGATCATTGAAGCGGTCGGTGCCGCTTCGCGCGAGCTGGAGGAATCGGCCGACGCCTTGGCC
AAGGGCAGCGCCGTGACGCTGCAGCTCTCCAATGTCGTCGCGACGGCGTCCACGGAGACGTCCAACAACGTGCAGTCGGT
GGCCTCGGCTGCCGAACAGATGAACGCGTCGGTCGGAGAAGTCGGACGCCAGGTCCGCGAATCGCGCAGCATCGCCGCCG
AAGCGGTGACGCAGGCCGAGCAGACCGATGCGCGGATCGCCAAGCTGGCACAGGCGGCCACCCGGATCGGCGACGTCACC
CAGCTCATCACCACCATTGCGGCGCAGACCAATCTGCTGGCGCTCAACGCGACCATCGAGGCCGCGCGCGCGGGCGAGGC
GGGCCGCGGCTTCGCCGTGGTCGCGCAGGAGGTCAAGGCACTGGCCGAACAGACCTCGAAGGCCACCGGCGAAATCAGCG
CACAGATCGCCGAGATCCAGTCCGCGACGCGGGAGTCGGTGGTCGCGATCAAGGAGATCGGCGGCACCATCGGGCGGGTC
GCCCATATCGCTTCGGCCGTCGCCGCCTCGGTCGACGAGCAGGGCACTGCCACGCAGGAGATTTCGCGCAGCGTCAGCCA
GGCCGCGGTCGGAACCAACCAGGTCGCGTCCAGCATCGCCGACGTCAATCGCGGTGCTGCGGACGCCGGGGCGGCGTCGT
CGCGCGTCCTCACGTCTGCGCAATTATTGTCCAACGAAAACGGCCGATTGCGCGTCGAAGTGCAAAAATTTCTCGCAACC
GTCCGGGTCGCTTAG

Upstream 100 bases:

>100_bases
CAACACCGCGGTCTGCGCGGGCGTCTACAAACTCTAGAGCGCGGCATTGCGTCGTCGCCGGCGAGAACCGGCGACGATCC
GACACTCGGGGACTTTCCTG

Downstream 100 bases:

>100_bases
CGTCCTGGTCGATGCTAGCTTGCATCTCGTGGGTGCCCGCAAATCCTGCGGGCCTCGACGGGAATGCCATGCTCTATCGT
CACGCTATCGGTAACGTCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MGRGIANIGLSWKVQLAPALLAIALIGIGVYALQALRTNQQSVDALVSGPVRSSELAADLNNAAWTAHAKLYRLAATAAN
ETDEAKLAQVSKEAIAAIARIPQALADVEKSLGGDSAIQKLKAAVAGYQKQAKNAIEMADGDAGSALLFIKSAEKSFTEI
DALISDLIVSSNDARDRQIAQAGIALDRQQWMLGAVLAVISLIGIAVSFLIGRGIARPVVAMSGAMHELASGNFDVRLPG
LERGDEVGRMARAVEAFKVQAASKAEREHAEREALERTAAAARRAELHQLADGFETAVGQIIEAVGAASRELEESADALA
KGSAVTLQLSNVVATASTETSNNVQSVASAAEQMNASVGEVGRQVRESRSIAAEAVTQAEQTDARIAKLAQAATRIGDVT
QLITTIAAQTNLLALNATIEAARAGEAGRGFAVVAQEVKALAEQTSKATGEISAQIAEIQSATRESVVAIKEIGGTIGRV
AHIASAVAASVDEQGTATQEISRSVSQAAVGTNQVASSIADVNRGAADAGAASSRVLTSAQLLSNENGRLRVEVQKFLAT
VRVA

Sequences:

>Translated_564_residues
MGRGIANIGLSWKVQLAPALLAIALIGIGVYALQALRTNQQSVDALVSGPVRSSELAADLNNAAWTAHAKLYRLAATAAN
ETDEAKLAQVSKEAIAAIARIPQALADVEKSLGGDSAIQKLKAAVAGYQKQAKNAIEMADGDAGSALLFIKSAEKSFTEI
DALISDLIVSSNDARDRQIAQAGIALDRQQWMLGAVLAVISLIGIAVSFLIGRGIARPVVAMSGAMHELASGNFDVRLPG
LERGDEVGRMARAVEAFKVQAASKAEREHAEREALERTAAAARRAELHQLADGFETAVGQIIEAVGAASRELEESADALA
KGSAVTLQLSNVVATASTETSNNVQSVASAAEQMNASVGEVGRQVRESRSIAAEAVTQAEQTDARIAKLAQAATRIGDVT
QLITTIAAQTNLLALNATIEAARAGEAGRGFAVVAQEVKALAEQTSKATGEISAQIAEIQSATRESVVAIKEIGGTIGRV
AHIASAVAASVDEQGTATQEISRSVSQAAVGTNQVASSIADVNRGAADAGAASSRVLTSAQLLSNENGRLRVEVQKFLAT
VRVA
>Mature_563_residues
GRGIANIGLSWKVQLAPALLAIALIGIGVYALQALRTNQQSVDALVSGPVRSSELAADLNNAAWTAHAKLYRLAATAANE
TDEAKLAQVSKEAIAAIARIPQALADVEKSLGGDSAIQKLKAAVAGYQKQAKNAIEMADGDAGSALLFIKSAEKSFTEID
ALISDLIVSSNDARDRQIAQAGIALDRQQWMLGAVLAVISLIGIAVSFLIGRGIARPVVAMSGAMHELASGNFDVRLPGL
ERGDEVGRMARAVEAFKVQAASKAEREHAEREALERTAAAARRAELHQLADGFETAVGQIIEAVGAASRELEESADALAK
GSAVTLQLSNVVATASTETSNNVQSVASAAEQMNASVGEVGRQVRESRSIAAEAVTQAEQTDARIAKLAQAATRIGDVTQ
LITTIAAQTNLLALNATIEAARAGEAGRGFAVVAQEVKALAEQTSKATGEISAQIAEIQSATRESVVAIKEIGGTIGRVA
HIASAVAASVDEQGTATQEISRSVSQAAVGTNQVASSIADVNRGAADAGAASSRVLTSAQLLSNENGRLRVEVQKFLATV
RVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=424, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788194, Length=184, Percent_Identity=35.3260869565217, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI2367378, Length=464, Percent_Identity=23.7068965517241, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788195, Length=238, Percent_Identity=30.672268907563, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=251, Percent_Identity=32.2709163346614, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58210; Mature: 58079

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGIANIGLSWKVQLAPALLAIALIGIGVYALQALRTNQQSVDALVSGPVRSSELAADL
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHH
NNAAWTAHAKLYRLAATAANETDEAKLAQVSKEAIAAIARIPQALADVEKSLGGDSAIQK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKAAVAGYQKQAKNAIEMADGDAGSALLFIKSAEKSFTEIDALISDLIVSSNDARDRQIA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHH
QAGIALDRQQWMLGAVLAVISLIGIAVSFLIGRGIARPVVAMSGAMHELASGNFDVRLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCC
LERGDEVGRMARAVEAFKVQAASKAEREHAEREALERTAAAARRAELHQLADGFETAVGQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIEAVGAASRELEESADALAKGSAVTLQLSNVVATASTETSNNVQSVASAAEQMNASVGE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
VGRQVRESRSIAAEAVTQAEQTDARIAKLAQAATRIGDVTQLITTIAAQTNLLALNATIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHH
AARAGEAGRGFAVVAQEVKALAEQTSKATGEISAQIAEIQSATRESVVAIKEIGGTIGRV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AHIASAVAASVDEQGTATQEISRSVSQAAVGTNQVASSIADVNRGAADAGAASSRVLTSA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QLLSNENGRLRVEVQKFLATVRVA
HHHCCCCCEEEEHHHHHHHHHCCC
>Mature Secondary Structure 
GRGIANIGLSWKVQLAPALLAIALIGIGVYALQALRTNQQSVDALVSGPVRSSELAADL
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHH
NNAAWTAHAKLYRLAATAANETDEAKLAQVSKEAIAAIARIPQALADVEKSLGGDSAIQK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKAAVAGYQKQAKNAIEMADGDAGSALLFIKSAEKSFTEIDALISDLIVSSNDARDRQIA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHH
QAGIALDRQQWMLGAVLAVISLIGIAVSFLIGRGIARPVVAMSGAMHELASGNFDVRLPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCC
LERGDEVGRMARAVEAFKVQAASKAEREHAEREALERTAAAARRAELHQLADGFETAVGQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIEAVGAASRELEESADALAKGSAVTLQLSNVVATASTETSNNVQSVASAAEQMNASVGE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCHHHH
VGRQVRESRSIAAEAVTQAEQTDARIAKLAQAATRIGDVTQLITTIAAQTNLLALNATIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHH
AARAGEAGRGFAVVAQEVKALAEQTSKATGEISAQIAEIQSATRESVVAIKEIGGTIGRV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AHIASAVAASVDEQGTATQEISRSVSQAAVGTNQVASSIADVNRGAADAGAASSRVLTSA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QLLSNENGRLRVEVQKFLATVRVA
HHHCCCCCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]