Click here to switch to the map view.

The map label for this gene is iorA [H]

Identifier: 86748791

GI number: 86748791

Start: 1897568

End: 1898158

Strand: Direct

Name: iorA [H]

Synonym: RPB_1668

Alternate gene names: 86748791

Gene position: 1897568-1898158 (Clockwise)

Preceding gene: 86748780

Following gene: 86748792

Centisome position: 35.59

GC content: 65.65

Gene sequence:

>591_bases
TTGCAGTGCACACTGTCCGAACCGGTCACGTGCCGTTTGCTGCAAGGCACAATTGACATGGCGTCTTCGGCTCTTACCGG
CGAACCCGTGGTGCTGACCGTCAACGGCACGACGTGCAGTGTCGATCTGCCCCGCGACACCAAGCTGATTTATGTGCTGC
GCAATGATCTCGGTCTCAACGGTCCGAAGTTCGGCTGCGGGCTCGGCGAATGTGGTGCGTGCACGGTGCTGATCGACGGC
GTTGCGGCGCGCTCCTGCGTGGTGACGCTCAGAACCGTCGAGGGGCGCTCCGTCACGACGCTGGAGGGCTTGGGCGAACT
CACTGCATTGCACCCGGTGCAGGCCGCGTTCATCGCCGCGCAGGCGGCGCAGTGCGGTTACTGCCTCAACGGCATGATCA
TGACCACGGTGGCGTTTCTCGCGCGCAACCCGGCGCCGACGCTCGAGCAGGTGCGCGAGGCGTTGCGCTACAATCTGTGC
CGCTGCGGCACCCATGTGGAAATCATGCGCGCCGTCATGGCCGCCGCCGGCGTGCGCGCGATCGAGGACGGCGTCGGCGC
AGATGATGTCGCGATGAGCGCTCCGCGATGA

Upstream 100 bases:

>100_bases
ACTGCAAAACGGCGCTTGACGTATTTTATTGGTGTAGAAACAATCACGACAGCGAGGTTGCCACGAATGCAGGTATCGGA
CGTGCCGGGACGAACTGAGT

Downstream 100 bases:

>100_bases
GTGAACCGACGCCGGCGCCGAAGGACCTGCTTGCTCGCACGGGCACGCTTGCCGTGTTGCGGCCGTCGCAGCACGTCAAG
GGCCTGGTGCCGACGGCGCC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MQCTLSEPVTCRLLQGTIDMASSALTGEPVVLTVNGTTCSVDLPRDTKLIYVLRNDLGLNGPKFGCGLGECGACTVLIDG
VAARSCVVTLRTVEGRSVTTLEGLGELTALHPVQAAFIAAQAAQCGYCLNGMIMTTVAFLARNPAPTLEQVREALRYNLC
RCGTHVEIMRAVMAAAGVRAIEDGVGADDVAMSAPR

Sequences:

>Translated_196_residues
MQCTLSEPVTCRLLQGTIDMASSALTGEPVVLTVNGTTCSVDLPRDTKLIYVLRNDLGLNGPKFGCGLGECGACTVLIDG
VAARSCVVTLRTVEGRSVTTLEGLGELTALHPVQAAFIAAQAAQCGYCLNGMIMTTVAFLARNPAPTLEQVREALRYNLC
RCGTHVEIMRAVMAAAGVRAIEDGVGADDVAMSAPR
>Mature_196_residues
MQCTLSEPVTCRLLQGTIDMASSALTGEPVVLTVNGTTCSVDLPRDTKLIYVLRNDLGLNGPKFGCGLGECGACTVLIDG
VAARSCVVTLRTVEGRSVTTLEGLGELTALHPVQAAFIAAQAAQCGYCLNGMIMTTVAFLARNPAPTLEQVREALRYNLC
RCGTHVEIMRAVMAAAGVRAIEDGVGADDVAMSAPR

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=164, Percent_Identity=34.7560975609756, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=40, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786480, Length=179, Percent_Identity=37.9888268156425, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=41.2587412587413, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=136, Percent_Identity=40.4411764705882, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17540638, Length=167, Percent_Identity=37.7245508982036, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=161, Percent_Identity=36.0248447204969, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=33.75, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17737937, Length=153, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647201, Length=175, Percent_Identity=30.2857142857143, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=31.1688311688312, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 20489; Mature: 20489

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCTLSEPVTCRLLQGTIDMASSALTGEPVVLTVNGTTCSVDLPRDTKLIYVLRNDLGLN
CCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEEEEEEECCCCCC
GPKFGCGLGECGACTVLIDGVAARSCVVTLRTVEGRSVTTLEGLGELTALHPVQAAFIAA
CCCCCCCCCCCCEEEEEECCHHHCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
QAAQCGYCLNGMIMTTVAFLARNPAPTLEQVREALRYNLCRCGTHVEIMRAVMAAAGVRA
HHHHCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHH
IEDGVGADDVAMSAPR
HHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQCTLSEPVTCRLLQGTIDMASSALTGEPVVLTVNGTTCSVDLPRDTKLIYVLRNDLGLN
CCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEEEEEEECCCCCC
GPKFGCGLGECGACTVLIDGVAARSCVVTLRTVEGRSVTTLEGLGELTALHPVQAAFIAA
CCCCCCCCCCCCEEEEEECCHHHCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
QAAQCGYCLNGMIMTTVAFLARNPAPTLEQVREALRYNLCRCGTHVEIMRAVMAAAGVRA
HHHHCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHH
IEDGVGADDVAMSAPR
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]