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The map label for this gene is cutL [H]

Identifier: 86748737

GI number: 86748737

Start: 1818988

End: 1821291

Strand: Direct

Name: cutL [H]

Synonym: RPB_1613

Alternate gene names: 86748737

Gene position: 1818988-1821291 (Clockwise)

Preceding gene: 86748736

Following gene: 86748738

Centisome position: 34.12

GC content: 66.19

Gene sequence:

>2304_bases
ATGGCTCCTACCAAATTCGGCGTCGGCCAAAGCGTGATGCGCAAGGAGGATGATCCCCTGATCCGCGGCAAGGGCCGCTA
TACCGACGACTACGCGCCGCAATCCTCGGCGCACGCGCTGGTGCTGCGATCACCGCATGCGCATGCGAAATTCAGGCTCG
ACGCGACGGCGGCGCGCGGCCTGCACGGCGTGCTCGCGATCCTCACCGCCGAAGACGTCAGCGATCTCGGCGGGCTGCCG
TGCCTGTTCAACCTACCCGACAATCCGTTCAAGGGGCCGGACTACGCGATCCTCGCCGGCGGCGAGGTGCGTCATGTCGG
CGACGCAGTGGCCTTCGTGGTCGCGGATACGGTGGCGCATGCGCGCGACGCGCTGGAGGCGATCGCGGTCGAATGGACGC
CGCTGCCGGCGGCGATCGGCGCGGCCAATGCGATCAAGCCCGGCGCGCCGCAGGTGTGGCCGGACCACGCCGGCAATCTG
CTGTTCGACACCGCGATCGGCGACAAGGCCGCAACAGAGGCCGCGTTCGCGAAGGCTCATGCCGTCGCCGAGATCGCCAT
CGTCAATCCGCGGATCATCACCAACTACATGGAGACCCGCGCCGCGGTCTGCGAATATGACGCCAAGCGCGATCATTTCA
CGCTGACGATCGGCAGCCAGGGCAGCCACCGGCTGCGTGATATCCTGTGCCAGAACGTGCTGAAAATTCCGGTCGAGAAG
ATGCGGGTGATCTGCCCCGATGTCGGCGGCGGCTTCGGCACCAAGCTGTTTCCGTATCGCGAATACGCGCTGCTGGCGGT
CGCGGCTAAGAAGCTCGGCAAGACCATCCGCTGGGCGGCCGACCGCTCCGATCATTTCGTCGGCGACTCGCAGGGCCGCG
ACAACATCACCACGGCGCGGATGGCGCTCGCGGCGGATGGCAAGTTTCTCGGCATGGACGTCGACCTGATCGGCGATCTC
GGCGCCTATCTGTCGACCTTCGGGCCTTACATCCCGTATGGCGGCGCCGGAATGTTGCCGGGGCTCTACGACATTCAGGC
GTTTTACTGCCGCATCCGGACGGTGTTCACCCACACTGTTCCAGTCGATGCCTATCGCGGCGCCGGTCGGCCCGAAGCGG
CCTATGTCATCGAACGTCTGGTCGATGCCTGCGCGCGCAAGCTCGGGATGTCGCCGGATGCGATCCGGCGCAAGAATTTC
ATCGCGCCGCGCGCGATGCCCTACAAGACTGCGACCGGCAAGGTCTACGACTCCGGTGATTTCGCCGCGCATCTGAAACG
CGCGATGGACATCGGCGAGTGGAAGGAATTTCCGAAGCGCGCCAAGGCAGCGACGAAACTCGGGCTGGTGCGCGGCATCG
GCCTGGCCTCCTATGTCGAAGTCTGCGGCACGATGGGCGAGGAGACCGCCAAGGTCGTGCTCGATCCCGACGGCGACATC
ACCGTTCTGATCGGCACCCAGTCGAGCGGGCAGGGCCATCAGACCGCCTATGCGCAGATCGTCGCCGAACAGTTCGGCGT
GCCGCCGGAGCGCGTCCGCGTGGTTCAGGGCGACACCGACAGGATTGCGACCGGGCTCGGCACCGGCGGCTCGGCATCGA
TCCCCTCGGGCGGCGTCAGCGTTCAACGCGCGACGCACCAAATCGGCGAGCAGATTCGCGAGTTGGCCGCGGACGCGCTG
GAAGCCGGCGCTGCGGATCTCGAAATCAGCGACGGCATCGTCCGCATCGCCGGCACCGACCGCTCGATCTCGTTCGCCGA
TCTCGCCAAGCGCCCCGGCCTCGATCCGGCCAAGCTGAATGCCAGCGCGACGTTCTCCAGCGCCGACGGCACGTTCCCAA
ACGGCACGCATTTGGTCGAAGTCGAGATCGATCCGGCGACCGGCAAAATCCGGATCGTCAACTACGTCATCGTCGACGAT
TTCGGCGTGACGCTGAACCCGCTGCTGCTCGCCGGCCAGGTTCATGGCGGCACCATCCAGGGCATCGGGCAGGCGCTGAT
GGAGCGGGCGGTGTACGATCAGGACGGCCAGCTCGTCACCGGCACCTTCATGGATTACGCGATGCCGCGCGCGGAGGATG
CCGCGCCGATCATCTTCGAGACTCACAACGTGCCGTGCACCACCAACCCGATGGGTGTGAAGGGGGCCGGCGAGGCCGGC
GCGATCGGCTCGTGCCCGGCCGTGGTCAATGCGATCATCGATGCCCTGTGGCGCGAGTACAAGATCGACCACATCGACAT
GCCGGCCACGCCGGAGCGGGTTTGGATGGCAATCCGCGAGCACCATCGGCAGCACAGTCTCTAG

Upstream 100 bases:

>100_bases
TGTACGCTTTTGGCTTGGTTAGTGCCGCCACTGAGCAATGGCGTTTGCACCGATCCGCGATCCGCTGCAAGATGCACCAC
CGCATCCAATGAGGTGATCG

Downstream 100 bases:

>100_bases
AGCCGCAGTTGGATCGGACCAGTCGAGCCGGTATTCACTTCGATCGACGACGCGTGCTTGTTGACGATTGCGTGATCGGA
GAAGCGCCATGGTACGATCG

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MAPTKFGVGQSVMRKEDDPLIRGKGRYTDDYAPQSSAHALVLRSPHAHAKFRLDATAARGLHGVLAILTAEDVSDLGGLP
CLFNLPDNPFKGPDYAILAGGEVRHVGDAVAFVVADTVAHARDALEAIAVEWTPLPAAIGAANAIKPGAPQVWPDHAGNL
LFDTAIGDKAATEAAFAKAHAVAEIAIVNPRIITNYMETRAAVCEYDAKRDHFTLTIGSQGSHRLRDILCQNVLKIPVEK
MRVICPDVGGGFGTKLFPYREYALLAVAAKKLGKTIRWAADRSDHFVGDSQGRDNITTARMALAADGKFLGMDVDLIGDL
GAYLSTFGPYIPYGGAGMLPGLYDIQAFYCRIRTVFTHTVPVDAYRGAGRPEAAYVIERLVDACARKLGMSPDAIRRKNF
IAPRAMPYKTATGKVYDSGDFAAHLKRAMDIGEWKEFPKRAKAATKLGLVRGIGLASYVEVCGTMGEETAKVVLDPDGDI
TVLIGTQSSGQGHQTAYAQIVAEQFGVPPERVRVVQGDTDRIATGLGTGGSASIPSGGVSVQRATHQIGEQIRELAADAL
EAGAADLEISDGIVRIAGTDRSISFADLAKRPGLDPAKLNASATFSSADGTFPNGTHLVEVEIDPATGKIRIVNYVIVDD
FGVTLNPLLLAGQVHGGTIQGIGQALMERAVYDQDGQLVTGTFMDYAMPRAEDAAPIIFETHNVPCTTNPMGVKGAGEAG
AIGSCPAVVNAIIDALWREYKIDHIDMPATPERVWMAIREHHRQHSL

Sequences:

>Translated_767_residues
MAPTKFGVGQSVMRKEDDPLIRGKGRYTDDYAPQSSAHALVLRSPHAHAKFRLDATAARGLHGVLAILTAEDVSDLGGLP
CLFNLPDNPFKGPDYAILAGGEVRHVGDAVAFVVADTVAHARDALEAIAVEWTPLPAAIGAANAIKPGAPQVWPDHAGNL
LFDTAIGDKAATEAAFAKAHAVAEIAIVNPRIITNYMETRAAVCEYDAKRDHFTLTIGSQGSHRLRDILCQNVLKIPVEK
MRVICPDVGGGFGTKLFPYREYALLAVAAKKLGKTIRWAADRSDHFVGDSQGRDNITTARMALAADGKFLGMDVDLIGDL
GAYLSTFGPYIPYGGAGMLPGLYDIQAFYCRIRTVFTHTVPVDAYRGAGRPEAAYVIERLVDACARKLGMSPDAIRRKNF
IAPRAMPYKTATGKVYDSGDFAAHLKRAMDIGEWKEFPKRAKAATKLGLVRGIGLASYVEVCGTMGEETAKVVLDPDGDI
TVLIGTQSSGQGHQTAYAQIVAEQFGVPPERVRVVQGDTDRIATGLGTGGSASIPSGGVSVQRATHQIGEQIRELAADAL
EAGAADLEISDGIVRIAGTDRSISFADLAKRPGLDPAKLNASATFSSADGTFPNGTHLVEVEIDPATGKIRIVNYVIVDD
FGVTLNPLLLAGQVHGGTIQGIGQALMERAVYDQDGQLVTGTFMDYAMPRAEDAAPIIFETHNVPCTTNPMGVKGAGEAG
AIGSCPAVVNAIIDALWREYKIDHIDMPATPERVWMAIREHHRQHSL
>Mature_766_residues
APTKFGVGQSVMRKEDDPLIRGKGRYTDDYAPQSSAHALVLRSPHAHAKFRLDATAARGLHGVLAILTAEDVSDLGGLPC
LFNLPDNPFKGPDYAILAGGEVRHVGDAVAFVVADTVAHARDALEAIAVEWTPLPAAIGAANAIKPGAPQVWPDHAGNLL
FDTAIGDKAATEAAFAKAHAVAEIAIVNPRIITNYMETRAAVCEYDAKRDHFTLTIGSQGSHRLRDILCQNVLKIPVEKM
RVICPDVGGGFGTKLFPYREYALLAVAAKKLGKTIRWAADRSDHFVGDSQGRDNITTARMALAADGKFLGMDVDLIGDLG
AYLSTFGPYIPYGGAGMLPGLYDIQAFYCRIRTVFTHTVPVDAYRGAGRPEAAYVIERLVDACARKLGMSPDAIRRKNFI
APRAMPYKTATGKVYDSGDFAAHLKRAMDIGEWKEFPKRAKAATKLGLVRGIGLASYVEVCGTMGEETAKVVLDPDGDIT
VLIGTQSSGQGHQTAYAQIVAEQFGVPPERVRVVQGDTDRIATGLGTGGSASIPSGGVSVQRATHQIGEQIRELAADALE
AGAADLEISDGIVRIAGTDRSISFADLAKRPGLDPAKLNASATFSSADGTFPNGTHLVEVEIDPATGKIRIVNYVIVDDF
GVTLNPLLLAGQVHGGTIQGIGQALMERAVYDQDGQLVTGTFMDYAMPRAEDAAPIIFETHNVPCTTNPMGVKGAGEAGA
IGSCPAVVNAIIDALWREYKIDHIDMPATPERVWMAIREHHRQHSL

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=778, Percent_Identity=23.7789203084833, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI91823271, Length=778, Percent_Identity=22.879177377892, Blast_Score=126, Evalue=1e-28,
Organism=Escherichia coli, GI1789230, Length=762, Percent_Identity=30.7086614173228, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789246, Length=810, Percent_Identity=24.8148148148148, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786478, Length=745, Percent_Identity=26.4429530201342, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=775, Percent_Identity=25.0322580645161, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17540638, Length=789, Percent_Identity=24.5880861850444, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32566215, Length=564, Percent_Identity=25.354609929078, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17737937, Length=726, Percent_Identity=24.6556473829201, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647193, Length=756, Percent_Identity=22.8835978835979, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647199, Length=510, Percent_Identity=23.921568627451, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647197, Length=323, Percent_Identity=29.1021671826625, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647195, Length=294, Percent_Identity=30.2721088435374, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81770; Mature: 81639

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTKFGVGQSVMRKEDDPLIRGKGRYTDDYAPQSSAHALVLRSPHAHAKFRLDATAARG
CCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHCC
LHGVLAILTAEDVSDLGGLPCLFNLPDNPFKGPDYAILAGGEVRHVGDAVAFVVADTVAH
HHHHEEEEEHHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHH
ARDALEAIAVEWTPLPAAIGAANAIKPGAPQVWPDHAGNLLFDTAIGDKAATEAAFAKAH
HHHHHHHHEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
AVAEIAIVNPRIITNYMETRAAVCEYDAKRDHFTLTIGSQGSHRLRDILCQNVLKIPVEK
HHEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHH
MRVICPDVGGGFGTKLFPYREYALLAVAAKKLGKTIRWAADRSDHFVGDSQGRDNITTAR
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHH
MALAADGKFLGMDVDLIGDLGAYLSTFGPYIPYGGAGMLPGLYDIQAFYCRIRTVFTHTV
EEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEC
PVDAYRGAGRPEAAYVIERLVDACARKLGMSPDAIRRKNFIAPRAMPYKTATGKVYDSGD
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCH
FAAHLKRAMDIGEWKEFPKRAKAATKLGLVRGIGLASYVEVCGTMGEETAKVVLDPDGDI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCE
TVLIGTQSSGQGHQTAYAQIVAEQFGVPPERVRVVQGDTDRIATGLGTGGSASIPSGGVS
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHCCCCCCCCCCCCCCCH
VQRATHQIGEQIRELAADALEAGAADLEISDGIVRIAGTDRSISFADLAKRPGLDPAKLN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHCCCCCHHHCC
ASATFSSADGTFPNGTHLVEVEIDPATGKIRIVNYVIVDDFGVTLNPLLLAGQVHGGTIQ
CCEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCHHH
GIGQALMERAVYDQDGQLVTGTFMDYAMPRAEDAAPIIFETHNVPCTTNPMGVKGAGEAG
HHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
AIGSCPAVVNAIIDALWREYKIDHIDMPATPERVWMAIREHHRQHSL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
APTKFGVGQSVMRKEDDPLIRGKGRYTDDYAPQSSAHALVLRSPHAHAKFRLDATAARG
CCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHCC
LHGVLAILTAEDVSDLGGLPCLFNLPDNPFKGPDYAILAGGEVRHVGDAVAFVVADTVAH
HHHHEEEEEHHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCEEHHHHHHHHHHHHHHHH
ARDALEAIAVEWTPLPAAIGAANAIKPGAPQVWPDHAGNLLFDTAIGDKAATEAAFAKAH
HHHHHHHHEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
AVAEIAIVNPRIITNYMETRAAVCEYDAKRDHFTLTIGSQGSHRLRDILCQNVLKIPVEK
HHEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHH
MRVICPDVGGGFGTKLFPYREYALLAVAAKKLGKTIRWAADRSDHFVGDSQGRDNITTAR
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHH
MALAADGKFLGMDVDLIGDLGAYLSTFGPYIPYGGAGMLPGLYDIQAFYCRIRTVFTHTV
EEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEC
PVDAYRGAGRPEAAYVIERLVDACARKLGMSPDAIRRKNFIAPRAMPYKTATGKVYDSGD
CCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCH
FAAHLKRAMDIGEWKEFPKRAKAATKLGLVRGIGLASYVEVCGTMGEETAKVVLDPDGDI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCE
TVLIGTQSSGQGHQTAYAQIVAEQFGVPPERVRVVQGDTDRIATGLGTGGSASIPSGGVS
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHCCCCCCCCCCCCCCCH
VQRATHQIGEQIRELAADALEAGAADLEISDGIVRIAGTDRSISFADLAKRPGLDPAKLN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHCCCCCHHHCC
ASATFSSADGTFPNGTHLVEVEIDPATGKIRIVNYVIVDDFGVTLNPLLLAGQVHGGTIQ
CCEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCHHH
GIGQALMERAVYDQDGQLVTGTFMDYAMPRAEDAAPIIFETHNVPCTTNPMGVKGAGEAG
HHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
AIGSCPAVVNAIIDALWREYKIDHIDMPATPERVWMAIREHHRQHSL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]