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The map label for this gene is adhR [H]

Identifier: 86748694

GI number: 86748694

Start: 1767678

End: 1768112

Strand: Reverse

Name: adhR [H]

Synonym: RPB_1569

Alternate gene names: 86748694

Gene position: 1768112-1767678 (Counterclockwise)

Preceding gene: 86748695

Following gene: 86748693

Centisome position: 33.16

GC content: 67.59

Gene sequence:

>435_bases
ATGAAGATCGGCGACCTCGCTAGGCGAACCGGGCTGACCGCCCATACGCTGCGCTATTACGAGCGGATCGGGCTGTTGCC
CCGCGCCTCGCGCGATGCGTCGGGCCAGCGTGACTACGACGCCTCGATCCTGGTCTGGATCGCGTTTCTCGGTCGCCTCA
AGACCACCGGGATGCCGATCCGGGACATGCTGCGCTACGCGAAACTACGCGCCCGCGGGGCTGCGACGGAGGACGCCCGA
CGCGTCCTGCTGCAGCAGCACCGCGACAAGGTGCAGGCGCATGTCGCCGAACTCAAAGCCTGCCTGACCGTCCTCGACAC
CAAGATCGCCGGCTATGCCGCCGGCGCCAGCAAGGTGGAGACGGACGATGACGCAACTCACAACCGACCAGCACGAAAGG
TACGCGCGCGGGCTGCGCGCGCTCGCGGCGATTGA

Upstream 100 bases:

>100_bases
GCCGGCCGGGGGCGCCCATCCTCTACCGTCCCGATTTGCGCTTGACTTCGAGCGCGCTCTAACCTGTAGCAACAGGGCGT
CGTGACGGACAGAGCAGGCC

Downstream 100 bases:

>100_bases
CGGCGACGCCGGCCACAAGGTGATCGATTCGCTGGCCGAGATCGCGCCGGATTTCGCCCGCTATGTGATCGAGTTTCCGT
TCGGCGACATCTACAGCCGC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKIGDLARRTGLTAHTLRYYERIGLLPRASRDASGQRDYDASILVWIAFLGRLKTTGMPIRDMLRYAKLRARGAATEDAR
RVLLQQHRDKVQAHVAELKACLTVLDTKIAGYAAGASKVETDDDATHNRPARKVRARAARARGD

Sequences:

>Translated_144_residues
MKIGDLARRTGLTAHTLRYYERIGLLPRASRDASGQRDYDASILVWIAFLGRLKTTGMPIRDMLRYAKLRARGAATEDAR
RVLLQQHRDKVQAHVAELKACLTVLDTKIAGYAAGASKVETDDDATHNRPARKVRARAARARGD
>Mature_144_residues
MKIGDLARRTGLTAHTLRYYERIGLLPRASRDASGQRDYDASILVWIAFLGRLKTTGMPIRDMLRYAKLRARGAATEDAR
RVLLQQHRDKVQAHVAELKACLTVLDTKIAGYAAGASKVETDDDATHNRPARKVRARAARARGD

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16040; Mature: 16040

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGDLARRTGLTAHTLRYYERIGLLPRASRDASGQRDYDASILVWIAFLGRLKTTGMPI
CCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
RDMLRYAKLRARGAATEDARRVLLQQHRDKVQAHVAELKACLTVLDTKIAGYAAGASKVE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDDDATHNRPARKVRARAARARGD
CCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIGDLARRTGLTAHTLRYYERIGLLPRASRDASGQRDYDASILVWIAFLGRLKTTGMPI
CCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
RDMLRYAKLRARGAATEDARRVLLQQHRDKVQAHVAELKACLTVLDTKIAGYAAGASKVE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDDDATHNRPARKVRARAARARGD
CCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]