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The map label for this gene is trxB [H]

Identifier: 86748637

GI number: 86748637

Start: 1704816

End: 1705781

Strand: Reverse

Name: trxB [H]

Synonym: RPB_1512

Alternate gene names: 86748637

Gene position: 1705781-1704816 (Counterclockwise)

Preceding gene: 86748639

Following gene: 86748636

Centisome position: 31.99

GC content: 67.7

Gene sequence:

>966_bases
GTGCCCAGTCGAGTCCAGGCTAAAGTCGTGATCATCGGTTCCGGGCCGGCCGGTTACACCGCCGCGATCTATGCCGCGCG
AGCCATGCTCGAGCCGATCCTGATCCAGGGCATCCAGCCCGGCGGGCAGCTCACCATCACCACCGATGTCGAGAACTATC
CGGGCTTCGCCGACGTCATCCAGGGCCCCTGGCTGATGGAGCAGATGGAGCGGCAGGCCCGGCACGTCGGAACCAAGATC
GTGACCGACCTCGTGGTCGATCTCGACCTCAACCAGCGGCCGTTCCGGCTGACCTGCGACAGCGGCGACGTCTACATCGC
CGAGACCGTGATCCTGGCCACCGGCGCGCAGGCGCGCTGGCTCGGCATCCCGTCGGAGCAGACCTACAAGGGCTTCGGCG
TCTCGGCCTGCGCGACCTGCGACGGCTTCTTCTATCGCGGCAAGGACGTCGTCGTGGTCGGCGGCGGCAACACCGCGGTC
GAGGAAGCGCTGTTCCTGACCAACTTCGCCGCCAGCGTCACCATCGTGCATCGCCGCGATCATTTCCGCGCCGAGCGCAT
CCTGCAGGAGCGCCTGTTCAAGCACCCGAAGATCAAGGTGGTGTGGGACAGCGAGGTCGACGAGATCTGCGGCAGCGACA
GCCCGACCAAGGTCACGCATGTCCGGCTGAAGAACGTCAAGACCGGTGCGCTCAGCGAGGTTCGCGCCGACGGCGTCTTC
ATCGCGATCGGTCACGCGCCGGCGACCGAACTGGTCAAGGACCAGCTCCGGCTGAAGCCGTCGGGCTACGTCGAAGTCGC
CCCGAACTCCACCGCGACCTCGGTCCCCGGCGTGTTCGCCGCGGGCGATGTCGCCGATGAAATCTATCGCCAGGCCGTCA
CCGCCGCGGGCCTCGGCTGCATGGCCGCGCTGGAAGCCGAACGCTTCCTCGCCCTGCGCGCCAGCGAACGCCAGGCGGCG
GAGTAG

Upstream 100 bases:

>100_bases
CCAGATGACATAGACTTCCGAATGAATCGTCCGCGCAACGGCGATGTCCCTGCCAGGCAAATCCCTGCTTCGCGCCGCCC
TAAATCTGGGGAGCTGAAAC

Downstream 100 bases:

>100_bases
ACATGGCTCGACACCGCGACGGGTTCACCGATATGGATTGGGATAAGCTCAAGGTCTTCCACGCCGCCGCCGAAGCCGGC
AGCTTCACCCATGCGGGTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPSRVQAKVVIIGSGPAGYTAAIYAARAMLEPILIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMERQARHVGTKI
VTDLVVDLDLNQRPFRLTCDSGDVYIAETVILATGAQARWLGIPSEQTYKGFGVSACATCDGFFYRGKDVVVVGGGNTAV
EEALFLTNFAASVTIVHRRDHFRAERILQERLFKHPKIKVVWDSEVDEICGSDSPTKVTHVRLKNVKTGALSEVRADGVF
IAIGHAPATELVKDQLRLKPSGYVEVAPNSTATSVPGVFAAGDVADEIYRQAVTAAGLGCMAALEAERFLALRASERQAA
E

Sequences:

>Translated_321_residues
MPSRVQAKVVIIGSGPAGYTAAIYAARAMLEPILIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMERQARHVGTKI
VTDLVVDLDLNQRPFRLTCDSGDVYIAETVILATGAQARWLGIPSEQTYKGFGVSACATCDGFFYRGKDVVVVGGGNTAV
EEALFLTNFAASVTIVHRRDHFRAERILQERLFKHPKIKVVWDSEVDEICGSDSPTKVTHVRLKNVKTGALSEVRADGVF
IAIGHAPATELVKDQLRLKPSGYVEVAPNSTATSVPGVFAAGDVADEIYRQAVTAAGLGCMAALEAERFLALRASERQAA
E
>Mature_320_residues
PSRVQAKVVIIGSGPAGYTAAIYAARAMLEPILIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMERQARHVGTKIV
TDLVVDLDLNQRPFRLTCDSGDVYIAETVILATGAQARWLGIPSEQTYKGFGVSACATCDGFFYRGKDVVVVGGGNTAVE
EALFLTNFAASVTIVHRRDHFRAERILQERLFKHPKIKVVWDSEVDEICGSDSPTKVTHVRLKNVKTGALSEVRADGVFI
AIGHAPATELVKDQLRLKPSGYVEVAPNSTATSVPGVFAAGDVADEIYRQAVTAAGLGCMAALEAERFLALRASERQAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI65787454, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI21389617, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=52.2012578616352, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI87081763, Length=309, Percent_Identity=31.7152103559871, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=47.3186119873817, Blast_Score=295, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=45.5696202531646, Blast_Score=282, Evalue=6e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34588; Mature: 34457

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRVQAKVVIIGSGPAGYTAAIYAARAMLEPILIQGIQPGGQLTITTDVENYPGFADVI
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
QGPWLMEQMERQARHVGTKIVTDLVVDLDLNQRPFRLTCDSGDVYIAETVILATGAQARW
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCEEE
LGIPSEQTYKGFGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFAASVTIVHRRD
EECCCCCCCCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHCEEEEEEECCH
HFRAERILQERLFKHPKIKVVWDSEVDEICGSDSPTKVTHVRLKNVKTGALSEVRADGVF
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHCCCCEE
IAIGHAPATELVKDQLRLKPSGYVEVAPNSTATSVPGVFAAGDVADEIYRQAVTAAGLGC
EEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHCHHH
MAALEAERFLALRASERQAAE
HHHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure 
PSRVQAKVVIIGSGPAGYTAAIYAARAMLEPILIQGIQPGGQLTITTDVENYPGFADVI
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
QGPWLMEQMERQARHVGTKIVTDLVVDLDLNQRPFRLTCDSGDVYIAETVILATGAQARW
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCEEE
LGIPSEQTYKGFGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFAASVTIVHRRD
EECCCCCCCCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHCEEEEEEECCH
HFRAERILQERLFKHPKIKVVWDSEVDEICGSDSPTKVTHVRLKNVKTGALSEVRADGVF
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHCCCCEE
IAIGHAPATELVKDQLRLKPSGYVEVAPNSTATSVPGVFAAGDVADEIYRQAVTAAGLGC
EEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHCHHH
MAALEAERFLALRASERQAAE
HHHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA