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The map label for this gene is crp [C]

Identifier: 86748611

GI number: 86748611

Start: 1675732

End: 1676454

Strand: Reverse

Name: crp [C]

Synonym: RPB_1486

Alternate gene names: 86748611

Gene position: 1676454-1675732 (Counterclockwise)

Preceding gene: 86748612

Following gene: 86748610

Centisome position: 31.44

GC content: 68.05

Gene sequence:

>723_bases
TTGGGACCAAGCATTGCAACCGAGGACATCGAGACGGTGGATGCCGCGCGGAGCGATGCGGGGACGCATCGCTTTTTGCT
GCAGGCGCTACCGCCGCCCGACCTCGACCTGGTGATGCGCACCGGCCGGATCGTCTGGTTTCAGAACCGCGACTATCTGC
TGCGGCAGGGCGAGCCGGGCGACGGCATCCACATCATCCTGAGCGGCGTTGTCGAAAGCACCTATGTTGGTCAGCAACAG
CGCGAGCTGCTGCTGGCGACCTGGCATCAAGGAGACTTCGTCGGTGCTCCGCATGTGCTCGGTTATCATCTGCACAGCTG
GTCGGCGCGGGCGCTGGGACGGGTCGAGGCGCTGCATCTCGACCAGCCGGCGATCCGCCGCCTGATCGCGCTGTCGCCGG
CCTTCGCCGTTGCTCTGGTCGGCTGTCTCGGCTTCAAGGGCGAGGCCTATTCGGCGCTGGCGCAGACGCTGGGCGGCCAG
AAGGTCGGCGAGCGGCTGGCGCTGCTGCTGCTGAAGCTGTGCGAGGCCGCAGCTCAGGACGGCGACGGCCCAATTCCGCT
CGGCCGCATCACCCAGGCCAATCTGGCGCGGATGATCGGCGCCACGAGGCAGTCGATCAGCCTGGCGCTGACCCGGCTGC
AGGACGACGGCGTGATTTCGGCGGGCGCCACCACGCTGGTCGTCAACGACCTCACCGCGCTGCGTCGGCACGCCGGCGAG
TGA

Upstream 100 bases:

>100_bases
GTGAGAGGCGCGATGCAGGCCGCCGCGACGTCCGCCTTTGCCGCATTGCCAATAGTGGCAACAGGCCGTAGCCTTTCAGG
TGACGACCTGGAGGGCAGTG

Downstream 100 bases:

>100_bases
GCCGCGGCGCGACATCACGGACGCGACCGCCGCAGCGTCGAACTGACAATTAATTGCTCACAATGAATCCGGAAATGCCG
GATTTTGTCGGCGTCAACTC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: CRP/FNR Family Transcriptional Regulator; Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family; Cyclic-AMP Receptor-Like Protein

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MGPSIATEDIETVDAARSDAGTHRFLLQALPPPDLDLVMRTGRIVWFQNRDYLLRQGEPGDGIHIILSGVVESTYVGQQQ
RELLLATWHQGDFVGAPHVLGYHLHSWSARALGRVEALHLDQPAIRRLIALSPAFAVALVGCLGFKGEAYSALAQTLGGQ
KVGERLALLLLKLCEAAAQDGDGPIPLGRITQANLARMIGATRQSISLALTRLQDDGVISAGATTLVVNDLTALRRHAGE

Sequences:

>Translated_240_residues
MGPSIATEDIETVDAARSDAGTHRFLLQALPPPDLDLVMRTGRIVWFQNRDYLLRQGEPGDGIHIILSGVVESTYVGQQQ
RELLLATWHQGDFVGAPHVLGYHLHSWSARALGRVEALHLDQPAIRRLIALSPAFAVALVGCLGFKGEAYSALAQTLGGQ
KVGERLALLLLKLCEAAAQDGDGPIPLGRITQANLARMIGATRQSISLALTRLQDDGVISAGATTLVVNDLTALRRHAGE
>Mature_239_residues
GPSIATEDIETVDAARSDAGTHRFLLQALPPPDLDLVMRTGRIVWFQNRDYLLRQGEPGDGIHIILSGVVESTYVGQQQR
ELLLATWHQGDFVGAPHVLGYHLHSWSARALGRVEALHLDQPAIRRLIALSPAFAVALVGCLGFKGEAYSALAQTLGGQK
VGERLALLLLKLCEAAAQDGDGPIPLGRITQANLARMIGATRQSISLALTRLQDDGVISAGATTLVVNDLTALRRHAGE

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=201, Percent_Identity=25.8706467661692, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25731; Mature: 25600

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPSIATEDIETVDAARSDAGTHRFLLQALPPPDLDLVMRTGRIVWFQNRDYLLRQGEPG
CCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHEECCCEEEEECCCEEEECCCCC
DGIHIILSGVVESTYVGQQQRELLLATWHQGDFVGAPHVLGYHLHSWSARALGRVEALHL
CCCEEHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHEEEC
DQPAIRRLIALSPAFAVALVGCLGFKGEAYSALAQTLGGQKVGERLALLLLKLCEAAAQD
CCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GDGPIPLGRITQANLARMIGATRQSISLALTRLQDDGVISAGATTLVVNDLTALRRHAGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
GPSIATEDIETVDAARSDAGTHRFLLQALPPPDLDLVMRTGRIVWFQNRDYLLRQGEPG
CCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHEECCCEEEEECCCEEEECCCCC
DGIHIILSGVVESTYVGQQQRELLLATWHQGDFVGAPHVLGYHLHSWSARALGRVEALHL
CCCEEHHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHEEEC
DQPAIRRLIALSPAFAVALVGCLGFKGEAYSALAQTLGGQKVGERLALLLLKLCEAAAQD
CCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GDGPIPLGRITQANLARMIGATRQSISLALTRLQDDGVISAGATTLVVNDLTALRRHAGE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA