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The map label for this gene is hicB2 [H]

Identifier: 86748547

GI number: 86748547

Start: 1609995

End: 1610453

Strand: Direct

Name: hicB2 [H]

Synonym: RPB_1422

Alternate gene names: 86748547

Gene position: 1609995-1610453 (Clockwise)

Preceding gene: 86748546

Following gene: 86748550

Centisome position: 30.2

GC content: 64.71

Gene sequence:

>459_bases
GTGCCCGAAGAGGGGCTGACGATGAAGACATACGCCTACGCCGCGGAGTTCGAAGCGGGAGATCGCAAGGGGACGATCGT
CGTGAGCTTTCCCGACGTTCCGGAAGCGATCACCCAAGGTGACGATATCGCGGATGCCCGCGCGCAGGCGGAGGAGGCGT
TGGGTCTGGCGCTGCTGAGCTATCCGCAGCGCGAACTGCCACTGCCGAAGGTCAAGGCGAAGGGCAAGGGCGCGACCATG
ATCGCGGTTGCGGCGGACGTCGCTGCCAAGCTCGCTGTGCTCGAGGCGTTTGCGGTCGCCGGCATCAGCAAGAGCGAATT
CGCGCGCCGCATGAACAAGGATGAGAAAGAGGTTCGCCGAATCCTCGATCCCAAGCACCCGACCAAGCTACCCGCGATGG
TCCAGGCGCTACGTGCGCTGGGCAAGCGCCTGGTGGTCGGGATCGAGGAAGCAGCCTGA

Upstream 100 bases:

>100_bases
ATGGTCTATGTGGGCGATCGTCTCACGACCCTGCCGAGCCGCGAGATCGATCCGAAGACAGCGCGCAAGATCCGTAAGCA
GCTCGGTCTTGCCGAATGAC

Downstream 100 bases:

>100_bases
ATCGGGCTGCGGCCCTCACACATCCGTATCGGTCGGCCCCACATAGGCGATCCGCACCATGTTGGTGGCGCCGGGGGTGC
CGAGCGGGACGCCGGCGACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MPEEGLTMKTYAYAAEFEAGDRKGTIVVSFPDVPEAITQGDDIADARAQAEEALGLALLSYPQRELPLPKVKAKGKGATM
IAVAADVAAKLAVLEAFAVAGISKSEFARRMNKDEKEVRRILDPKHPTKLPAMVQALRALGKRLVVGIEEAA

Sequences:

>Translated_152_residues
MPEEGLTMKTYAYAAEFEAGDRKGTIVVSFPDVPEAITQGDDIADARAQAEEALGLALLSYPQRELPLPKVKAKGKGATM
IAVAADVAAKLAVLEAFAVAGISKSEFARRMNKDEKEVRRILDPKHPTKLPAMVQALRALGKRLVVGIEEAA
>Mature_151_residues
PEEGLTMKTYAYAAEFEAGDRKGTIVVSFPDVPEAITQGDDIADARAQAEEALGLALLSYPQRELPLPKVKAKGKGATMI
AVAADVAAKLAVLEAFAVAGISKSEFARRMNKDEKEVRRILDPKHPTKLPAMVQALRALGKRLVVGIEEAA

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA 2 toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693129, Length=122, Percent_Identity=36.8852459016393, Blast_Score=76, Evalue=9e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 16272; Mature: 16141

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEEGLTMKTYAYAAEFEAGDRKGTIVVSFPDVPEAITQGDDIADARAQAEEALGLALLS
CCCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
YPQRELPLPKVKAKGKGATMIAVAADVAAKLAVLEAFAVAGISKSEFARRMNKDEKEVRR
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
ILDPKHPTKLPAMVQALRALGKRLVVGIEEAA
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PEEGLTMKTYAYAAEFEAGDRKGTIVVSFPDVPEAITQGDDIADARAQAEEALGLALLS
CCCCCEEHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
YPQRELPLPKVKAKGKGATMIAVAADVAAKLAVLEAFAVAGISKSEFARRMNKDEKEVRR
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
ILDPKHPTKLPAMVQALRALGKRLVVGIEEAA
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]