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The map label for this gene is yoaE [H]

Identifier: 86748505

GI number: 86748505

Start: 1572044

End: 1574152

Strand: Direct

Name: yoaE [H]

Synonym: RPB_1380

Alternate gene names: 86748505

Gene position: 1572044-1574152 (Clockwise)

Preceding gene: 86748503

Following gene: 86748508

Centisome position: 29.49

GC content: 65.53

Gene sequence:

>2109_bases
ATGAGCCACGCCGAGATCGACATCCGCCACTCGACCTGTCCGCATGATTGCCCGTCGGCCTGTGCGCTCGACGTCGAGGT
GATCGACGGATCGACCATCGTTCGGGTGCGCGGTTCGAAGCTGCAGACATACACGGCCGGCGTCGTCTGCGCCAAAGTCG
CGCGCTACGCCGAGCGCATCCACCATCCCGACCGGCTGACATATCCGCTGCGGCGGTCCGGGCCGAAGGGGTCGGGGCAG
TTCGCCCGCATCACCTGGGACGAGGCACTGGACGAGATCGCGGCGCGGTTCGAGGCCGCCGAGACGGAGTTCGGCCCGGA
GTCGGTCTGGCCGTACTACTACGCAGGCACCATGGGCCTGGTGATGCGCGACGGCATCAACCGGCTCGCCAATATCAGGA
AATACTCGCGGTTCTACTCGACGATCTGCGCCAATATCGCCTGGTCCGGCTATGCCGCCGGCACCGGCAAGGTGGCGGGC
GTCGATCCGCGCGAGATGGCGAAGTCCGACCTGATCGTGATCTGGGGCACCAACGTGGTCTCCACCCAGGTCAACGTGAT
GACCCATGCGGCGCGTGCCCGCAAGGAGCGCGGCGCGCGGATTGCCGCGGTCGATATCTACGACAACGACACCATGAAGC
AGGCCGATATCCGGATCATCCTGCGTCCGGGCACGGACGGCGCCTTCGCCTGTGGCGTCATGCACGTTCTGTTTCGCGAC
GGTTACGCCGATCGCGACTATCTCGCCCGCTACACGGATTGCCCCGATGAGCTGGAGAGGCACCTGGCGACCCGGACTCC
CGAATGGGCGTCGTCGATCTGCGATGTGCCTGTGGCCGAGATCGAGGCGTTCGCCCATGCCATCGGTGAGACCAAGCGTA
GTTTCTTCAGGCTCGGCTACGGCTTCACCCGCAGCCGCAACGGGGCGGCTCAGATGCATGCGGCGCTGTGCATTCCGGCG
ATCACCGGCGCGTGGCAGCACGAAGGCGGCGGCGCTTTCTTCAACAACGGCGCCATTTTCGGCTTCGACAAGACGCTGAT
CGAGGGCCTCGACACGCTCGACCCCACGACCCGTGTGCTCGATCAGTCGAAGATCGGTCGCATCCTCACCGGCGACGCCG
AGGCGCTCGGTGGCGGCGCGCCGGTCAAGGCGATGCTGATTCAGAACACCAATCCGATGACGGTCGCGCCGGAGCAAACG
TTGGTCGGCGAGGGGTTCGCCCGCGAGGATCTGTTCGTTGCCGTACACGAGCAGTTCATGACCGAGACGGCGGCCATGGC
CGATATCGTGCTGCCGGCGACGATGTTTCTCGAGCACGACGATCTGTACTACGGAGGCGGTCACCAGCATATTTCGATCG
GCGCCAGGCTGGTCGCGCCGCCCGGGGAATGCCGGTCCAATCACGAAGTCCTGCAGGGACTGGCGACGAGGCTCGGCGTT
CGCCATCCCGCATTCGAGATGACACCGCGGGACGTGATCGACGCGACCCTGAAGAAAAGCGGTCGGGGAGGAATCGAGGC
GCTCGAGGCGGAGCTGTGGCGCGACCTGCAGCCGGATTTCCGCACCGCTCACTTCCTCGACGGCTTCGCGCATTCCGACG
GGAAGTTCCATTTTCGCGCGGATTGGAGACACGTCAACGTGCCGCGGCAGATCAAGCTTGGACCGTGGCAGTCGATGCCG
AGTCTGCCCGACCACTGGCCGGTGACCGAGCAGACTGATCACGCCCATCCGTTCCGGCTGGCGACCAGCCCGGCGCGGAG
CTTTCTCAATACGACGTTCAACGAGACGCCGTCGTCACGTGCGCGCGAAGGCACCCCGACGGTGCTGATACACCCGGCTG
ATGCTGAAACGATCGGGGTCGGGGAGGGGGATGCCGTCACGCTCGGCAATACGAGGGGCGAGACCACACTCACCGCCAAG
CTCGACGGCGGATTGCGCCGCGGCGTACTGATCGCCGAGTCGGTCTTCCCCAACAGCGCGCATGCCGGCGGTCGCGGGAT
CAACGTACTGACCAGCGCAGACTCGGTCGCGCCGCACGGCGGTGCCGCGTTTCACGACAATAAAGTATGGGCGAAGAAGA
CGTTACCGCCGCTCGCGAAGCGCGACTGA

Upstream 100 bases:

>100_bases
GGAGGAAGTTGCGCGGCCGGGAAGAGAATCCGGCTGCGCCCGACAGCATGGATACCGAGGAGCCATTCTCAATGATGGCC
TAATATGTTACCTTTGTTCG

Downstream 100 bases:

>100_bases
GCTCCGAAAATCCGGCAGCAGCCGGGAATCGGCAGTCGTTGATCGCTTCGCGAGGCGGGTTATGCCGGGCTCAGCGCTGG
TGGCCGAGGCCGATACCGAG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MSHAEIDIRHSTCPHDCPSACALDVEVIDGSTIVRVRGSKLQTYTAGVVCAKVARYAERIHHPDRLTYPLRRSGPKGSGQ
FARITWDEALDEIAARFEAAETEFGPESVWPYYYAGTMGLVMRDGINRLANIRKYSRFYSTICANIAWSGYAAGTGKVAG
VDPREMAKSDLIVIWGTNVVSTQVNVMTHAARARKERGARIAAVDIYDNDTMKQADIRIILRPGTDGAFACGVMHVLFRD
GYADRDYLARYTDCPDELERHLATRTPEWASSICDVPVAEIEAFAHAIGETKRSFFRLGYGFTRSRNGAAQMHAALCIPA
ITGAWQHEGGGAFFNNGAIFGFDKTLIEGLDTLDPTTRVLDQSKIGRILTGDAEALGGGAPVKAMLIQNTNPMTVAPEQT
LVGEGFAREDLFVAVHEQFMTETAAMADIVLPATMFLEHDDLYYGGGHQHISIGARLVAPPGECRSNHEVLQGLATRLGV
RHPAFEMTPRDVIDATLKKSGRGGIEALEAELWRDLQPDFRTAHFLDGFAHSDGKFHFRADWRHVNVPRQIKLGPWQSMP
SLPDHWPVTEQTDHAHPFRLATSPARSFLNTTFNETPSSRAREGTPTVLIHPADAETIGVGEGDAVTLGNTRGETTLTAK
LDGGLRRGVLIAESVFPNSAHAGGRGINVLTSADSVAPHGGAAFHDNKVWAKKTLPPLAKRD

Sequences:

>Translated_702_residues
MSHAEIDIRHSTCPHDCPSACALDVEVIDGSTIVRVRGSKLQTYTAGVVCAKVARYAERIHHPDRLTYPLRRSGPKGSGQ
FARITWDEALDEIAARFEAAETEFGPESVWPYYYAGTMGLVMRDGINRLANIRKYSRFYSTICANIAWSGYAAGTGKVAG
VDPREMAKSDLIVIWGTNVVSTQVNVMTHAARARKERGARIAAVDIYDNDTMKQADIRIILRPGTDGAFACGVMHVLFRD
GYADRDYLARYTDCPDELERHLATRTPEWASSICDVPVAEIEAFAHAIGETKRSFFRLGYGFTRSRNGAAQMHAALCIPA
ITGAWQHEGGGAFFNNGAIFGFDKTLIEGLDTLDPTTRVLDQSKIGRILTGDAEALGGGAPVKAMLIQNTNPMTVAPEQT
LVGEGFAREDLFVAVHEQFMTETAAMADIVLPATMFLEHDDLYYGGGHQHISIGARLVAPPGECRSNHEVLQGLATRLGV
RHPAFEMTPRDVIDATLKKSGRGGIEALEAELWRDLQPDFRTAHFLDGFAHSDGKFHFRADWRHVNVPRQIKLGPWQSMP
SLPDHWPVTEQTDHAHPFRLATSPARSFLNTTFNETPSSRAREGTPTVLIHPADAETIGVGEGDAVTLGNTRGETTLTAK
LDGGLRRGVLIAESVFPNSAHAGGRGINVLTSADSVAPHGGAAFHDNKVWAKKTLPPLAKRD
>Mature_701_residues
SHAEIDIRHSTCPHDCPSACALDVEVIDGSTIVRVRGSKLQTYTAGVVCAKVARYAERIHHPDRLTYPLRRSGPKGSGQF
ARITWDEALDEIAARFEAAETEFGPESVWPYYYAGTMGLVMRDGINRLANIRKYSRFYSTICANIAWSGYAAGTGKVAGV
DPREMAKSDLIVIWGTNVVSTQVNVMTHAARARKERGARIAAVDIYDNDTMKQADIRIILRPGTDGAFACGVMHVLFRDG
YADRDYLARYTDCPDELERHLATRTPEWASSICDVPVAEIEAFAHAIGETKRSFFRLGYGFTRSRNGAAQMHAALCIPAI
TGAWQHEGGGAFFNNGAIFGFDKTLIEGLDTLDPTTRVLDQSKIGRILTGDAEALGGGAPVKAMLIQNTNPMTVAPEQTL
VGEGFAREDLFVAVHEQFMTETAAMADIVLPATMFLEHDDLYYGGGHQHISIGARLVAPPGECRSNHEVLQGLATRLGVR
HPAFEMTPRDVIDATLKKSGRGGIEALEAELWRDLQPDFRTAHFLDGFAHSDGKFHFRADWRHVNVPRQIKLGPWQSMPS
LPDHWPVTEQTDHAHPFRLATSPARSFLNTTFNETPSSRAREGTPTVLIHPADAETIGVGEGDAVTLGNTRGETTLTAKL
DGGLRRGVLIAESVFPNSAHAGGRGINVLTSADSVAPHGGAAFHDNKVWAKKTLPPLAKRD

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=725, Percent_Identity=25.7931034482759, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI87081797, Length=764, Percent_Identity=25.130890052356, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI171474008, Length=777, Percent_Identity=24.4530244530245, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI145693196, Length=727, Percent_Identity=25.3094910591472, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI3868721, Length=504, Percent_Identity=24.8015873015873, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081994, Length=729, Percent_Identity=22.6337448559671, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787231, Length=681, Percent_Identity=20.9985315712188, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 76611; Mature: 76480

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAEIDIRHSTCPHDCPSACALDVEVIDGSTIVRVRGSKLQTYTAGVVCAKVARYAERI
CCCCEEEEECCCCCCCCCCHHEEEEEEECCCEEEEEECCEEEEHHHHHHHHHHHHHHHHH
HHPDRLTYPLRRSGPKGSGQFARITWDEALDEIAARFEAAETEFGPESVWPYYYAGTMGL
CCCCCCCCCHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHH
VMRDGINRLANIRKYSRFYSTICANIAWSGYAAGTGKVAGVDPREMAKSDLIVIWGTNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCEE
STQVNVMTHAARARKERGARIAAVDIYDNDTMKQADIRIILRPGTDGAFACGVMHVLFRD
EHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
GYADRDYLARYTDCPDELERHLATRTPEWASSICDVPVAEIEAFAHAIGETKRSFFRLGY
CCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GFTRSRNGAAQMHAALCIPAITGAWQHEGGGAFFNNGAIFGFDKTLIEGLDTLDPTTRVL
CCCCCCCCHHHHHHHHHHHHHCCCCEECCCCEEECCCEEEECCHHHHHHHHCCCHHHHHH
DQSKIGRILTGDAEALGGGAPVKAMLIQNTNPMTVAPEQTLVGEGFAREDLFVAVHEQFM
HHHHCCCEEECCHHHCCCCCCEEEEEEECCCCCEECCCHHHHCCCCCCCHHHHHHHHHHH
TETAAMADIVLPATMFLEHDDLYYGGGHQHISIGARLVAPPGECRSNHEVLQGLATRLGV
HHHHHHHHHHHHHHHEEECCCEEECCCCCEEEECEEEECCCCCCCCHHHHHHHHHHHHCC
RHPAFEMTPRDVIDATLKKSGRGGIEALEAELWRDLQPDFRTAHFLDGFAHSDGKFHFRA
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEE
DWRHVNVPRQIKLGPWQSMPSLPDHWPVTEQTDHAHPFRLATSPARSFLNTTFNETPSSR
CCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCC
AREGTPTVLIHPADAETIGVGEGDAVTLGNTRGETTLTAKLDGGLRRGVLIAESVFPNSA
CCCCCCEEEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCC
HAGGRGINVLTSADSVAPHGGAAFHDNKVWAKKTLPPLAKRD
CCCCCCEEEEECCCCCCCCCCCEEECCCEEHHHCCCCCCCCC
>Mature Secondary Structure 
SHAEIDIRHSTCPHDCPSACALDVEVIDGSTIVRVRGSKLQTYTAGVVCAKVARYAERI
CCCEEEEECCCCCCCCCCHHEEEEEEECCCEEEEEECCEEEEHHHHHHHHHHHHHHHHH
HHPDRLTYPLRRSGPKGSGQFARITWDEALDEIAARFEAAETEFGPESVWPYYYAGTMGL
CCCCCCCCCHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHH
VMRDGINRLANIRKYSRFYSTICANIAWSGYAAGTGKVAGVDPREMAKSDLIVIWGTNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCEE
STQVNVMTHAARARKERGARIAAVDIYDNDTMKQADIRIILRPGTDGAFACGVMHVLFRD
EHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
GYADRDYLARYTDCPDELERHLATRTPEWASSICDVPVAEIEAFAHAIGETKRSFFRLGY
CCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GFTRSRNGAAQMHAALCIPAITGAWQHEGGGAFFNNGAIFGFDKTLIEGLDTLDPTTRVL
CCCCCCCCHHHHHHHHHHHHHCCCCEECCCCEEECCCEEEECCHHHHHHHHCCCHHHHHH
DQSKIGRILTGDAEALGGGAPVKAMLIQNTNPMTVAPEQTLVGEGFAREDLFVAVHEQFM
HHHHCCCEEECCHHHCCCCCCEEEEEEECCCCCEECCCHHHHCCCCCCCHHHHHHHHHHH
TETAAMADIVLPATMFLEHDDLYYGGGHQHISIGARLVAPPGECRSNHEVLQGLATRLGV
HHHHHHHHHHHHHHHEEECCCEEECCCCCEEEECEEEECCCCCCCCHHHHHHHHHHHHCC
RHPAFEMTPRDVIDATLKKSGRGGIEALEAELWRDLQPDFRTAHFLDGFAHSDGKFHFRA
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEE
DWRHVNVPRQIKLGPWQSMPSLPDHWPVTEQTDHAHPFRLATSPARSFLNTTFNETPSSR
CCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCC
AREGTPTVLIHPADAETIGVGEGDAVTLGNTRGETTLTAKLDGGLRRGVLIAESVFPNSA
CCCCCCEEEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCC
HAGGRGINVLTSADSVAPHGGAAFHDNKVWAKKTLPPLAKRD
CCCCCCEEEEECCCCCCCCCCCEEECCCEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]