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The map label for this gene is thrB

Identifier: 86748466

GI number: 86748466

Start: 1527685

End: 1528665

Strand: Direct

Name: thrB

Synonym: RPB_1341

Alternate gene names: 86748466

Gene position: 1527685-1528665 (Clockwise)

Preceding gene: 86748465

Following gene: 86748467

Centisome position: 28.65

GC content: 65.44

Gene sequence:

>981_bases
ATGGCGGTCTACACCGACGTCGCCGCCGACGACCTCGCGGATTTCCTCAAATCCTATGAGATCGGCGATCTGTTGTCCTA
CAAGGGCATCGCCGAGGGCGTCGAGAATACCAATTTCCTGCTGCACACCACGCGCGGCAGCTTCATTCTCACGCTGTACG
AGAAGCGCGTCGCCTCCGAGGATCTGCCGTATTTCCTGGCGCTGATGGCGCATCTGGCCGCGCGCGGCGTCAGTTGCCCG
CAGCCCGAAAAGACCCGCGACGGCGAGATCTGCGGCGCGTTGTCCGGCCGCCCGGCGGTGATCATCAATTTCCTCGAAGG
CGTCTGGCCGCGCCGTCCCAACGCGGTGCATTGCGCCGGCGTCGGCGAGGCGCTGGCCAAGATGCACCTCGCCGGCCTGG
ATTTTCCGCAGCATCGCGCCAATCCGCTGTCGGTGTCGGGCTGGCGGCCGCTGTTCGACCTCGCCGCCGCGCGCGCCGAC
GAGATCCAGCCAGGCTTGCGCGATTTCATCGCCGCCGAGCTCGATCACCTCGAAGGCCGCTGGCCGCGGCATCTGCCGAC
TGGCGTGATCCATGCCGATCTGTTTCCGGACAACGTTTTCTTCATCGGCGACACGCTGTCGGGACTGATCGACTTCCCGT
TCTCCTGCAACGACATCCTCGCCTACGACGTGGCGATCTGCCTGAATGCCTGGTGCTTCGAGCCGGACCACGCCTTCAAC
GTCACCAAGGCGCGGGCGCTGCTGAATGCGTATCAACGCGGCCGCGCCTTGAGCGAGGCCGAGCAGACGGCGCTGCCGCT
GCTGGCGCGCGGCGCGGCGATGCGCTTCCTGCTGACCCGGCTGGTCGATGTTCTCGACGTGCCGGAAGGCGCGCTGGTCA
AGCCGAAGGATCCGCTGGAATATTTCCGCAAGCTGCGCTTCCAGCAAAATGTCGCCAGCATTCGCGATTATGGTGTCGAA
GCTGCGGGAGCGGTGGCGTGA

Upstream 100 bases:

>100_bases
AGCGGTGGGGAAGGGGCCGGCCCCGGGGGCCCGCCCTTTCATTGCCGGGCGCGCTGGTCTAGGACACCGCCATCACTCCT
CACCACCCGGGACGCCCCCC

Downstream 100 bases:

>100_bases
GCGGGGCTCTGAGCGAAGCCGGGGCCGGCCCCCGCCCGGTGGTGATCCACACCGACGGTGCCTGTTCGGGCAACCCCGGC
CCCGGGGGGTGGGGGGCCAT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAVYTDVAADDLADFLKSYEIGDLLSYKGIAEGVENTNFLLHTTRGSFILTLYEKRVASEDLPYFLALMAHLAARGVSCP
QPEKTRDGEICGALSGRPAVIINFLEGVWPRRPNAVHCAGVGEALAKMHLAGLDFPQHRANPLSVSGWRPLFDLAAARAD
EIQPGLRDFIAAELDHLEGRWPRHLPTGVIHADLFPDNVFFIGDTLSGLIDFPFSCNDILAYDVAICLNAWCFEPDHAFN
VTKARALLNAYQRGRALSEAEQTALPLLARGAAMRFLLTRLVDVLDVPEGALVKPKDPLEYFRKLRFQQNVASIRDYGVE
AAGAVA

Sequences:

>Translated_326_residues
MAVYTDVAADDLADFLKSYEIGDLLSYKGIAEGVENTNFLLHTTRGSFILTLYEKRVASEDLPYFLALMAHLAARGVSCP
QPEKTRDGEICGALSGRPAVIINFLEGVWPRRPNAVHCAGVGEALAKMHLAGLDFPQHRANPLSVSGWRPLFDLAAARAD
EIQPGLRDFIAAELDHLEGRWPRHLPTGVIHADLFPDNVFFIGDTLSGLIDFPFSCNDILAYDVAICLNAWCFEPDHAFN
VTKARALLNAYQRGRALSEAEQTALPLLARGAAMRFLLTRLVDVLDVPEGALVKPKDPLEYFRKLRFQQNVASIRDYGVE
AAGAVA
>Mature_325_residues
AVYTDVAADDLADFLKSYEIGDLLSYKGIAEGVENTNFLLHTTRGSFILTLYEKRVASEDLPYFLALMAHLAARGVSCPQ
PEKTRDGEICGALSGRPAVIINFLEGVWPRRPNAVHCAGVGEALAKMHLAGLDFPQHRANPLSVSGWRPLFDLAAARADE
IQPGLRDFIAAELDHLEGRWPRHLPTGVIHADLFPDNVFFIGDTLSGLIDFPFSCNDILAYDVAICLNAWCFEPDHAFNV
TKARALLNAYQRGRALSEAEQTALPLLARGAAMRFLLTRLVDVLDVPEGALVKPKDPLEYFRKLRFQQNVASIRDYGVEA
AGAVA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_RHOP2 (Q2J0F9)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484962.1
- ProteinModelPortal:   Q2J0F9
- SMR:   Q2J0F9
- STRING:   Q2J0F9
- GeneID:   3907849
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_1341
- eggNOG:   COG2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- BioCyc:   RPAL316058:RPB_1341-MONOMER
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35832; Mature: 35701

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVAADDLADFLKSYEIGDLLSYKGIAEGVENTNFLLHTTRGSFILTLYEKRVASE
CCEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHCCC
DLPYFLALMAHLAARGVSCPQPEKTRDGEICGALSGRPAVIINFLEGVWPRRPNAVHCAG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEECC
VGEALAKMHLAGLDFPQHRANPLSVSGWRPLFDLAAARADEIQPGLRDFIAAELDHLEGR
HHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
WPRHLPTGVIHADLFPDNVFFIGDTLSGLIDFPFSCNDILAYDVAICLNAWCFEPDHAFN
CCCCCCCCEEEEECCCCCEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
VTKARALLNAYQRGRALSEAEQTALPLLARGAAMRFLLTRLVDVLDVPEGALVKPKDPLE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YFRKLRFQQNVASIRDYGVEAAGAVA
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AVYTDVAADDLADFLKSYEIGDLLSYKGIAEGVENTNFLLHTTRGSFILTLYEKRVASE
CEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHCCC
DLPYFLALMAHLAARGVSCPQPEKTRDGEICGALSGRPAVIINFLEGVWPRRPNAVHCAG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEECC
VGEALAKMHLAGLDFPQHRANPLSVSGWRPLFDLAAARADEIQPGLRDFIAAELDHLEGR
HHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
WPRHLPTGVIHADLFPDNVFFIGDTLSGLIDFPFSCNDILAYDVAICLNAWCFEPDHAFN
CCCCCCCCEEEEECCCCCEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
VTKARALLNAYQRGRALSEAEQTALPLLARGAAMRFLLTRLVDVLDVPEGALVKPKDPLE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YFRKLRFQQNVASIRDYGVEAAGAVA
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA