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The map label for this gene is mcp4 [H]

Identifier: 86748446

GI number: 86748446

Start: 1506578

End: 1508770

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1321

Alternate gene names: 86748446

Gene position: 1506578-1508770 (Clockwise)

Preceding gene: 86748445

Following gene: 86748449

Centisome position: 28.26

GC content: 63.57

Gene sequence:

>2193_bases
ATGAATTTCTCTTTCCGTGCCATCAAGACCGTGCAGCTCAAGATCGCTCTCGTATCGGGCCTGTGCCTGACCGGCGCCAG
CTTGATGCTGATCGTCTACAGCATCGTTTCGGCACAGAGCACCAACAGCTACGTCACCACGGAAGTCATGCAACTGGTCG
ACAGTCAGACCAAAGAGAGCCTGCTGAACCGCGGCTCAACCGAAGCCGGTTCGATCAAATCGGAGCTCGACGTCGGCCTC
GATGCCGCCCGCACCATGGCCCATGCGTTCGCCGTGCTCGCCGACGCCAAGAACAGCGGCACGCCGGACAGCAATCGCCG
GGCCCAGCTCAATGCGGTGCTGAACAACACCTTGAAACAGAACCCCGCCTTCAACGGCACCTATTCGGCATGGGAGCCGA
ATGCCCTGGACGGCAACGACGCGGCCTTCAAAGGCCGTCAGGACATGGGATCCGATACCACGGGTCGCTTCCTGCCGTAC
TGGACCCGGGGCGCCAGTGGCGCGATCGCGGTTCAGCCTCTCGTCGAATACGACAGCAGCGAACGCCACCCCAATGGTCT
GGTGAAGGGGGCGTGGTTCATCAATCCGCAAACCACCGGCAAGGAAAACATCCTGGGGCCGCTGCCCTACATTGTTCAAG
GCAAGCAGGTATTTCTCGCGACGATGTCGGTGCCGATCATGATCGGCGGCAAGTTCGTCGGTGTCGCGGGCGCCGACTAC
AATCTGGATTTCGTGCAGAAGCTCGCCAAGCAGGTCAACGCATCGCTGTATGACGGCAAGGGCAAGGTGGCGATCATCAA
CAACACCGGCCTGATCGTCGCCAACAGCGCCAATGATGCGACGATCGGCAAGCGCGCGGAGGAGGCCGATCCGCGCTGGG
CCGGTAGCCTCGCCATCGTGCAATCCGGCAAGGGCAAGGTGCTCGACGATCCGAAATCGAAGGACGTCGAAGTGTATTCG
CCGATCAATGTCGGCAGCACCGGAACGCCCTGGTCGGTGTTGATCTCGGTGCCGCGGGACGTGGTTCTGGCGTCCGCGAA
GAAGCTGGACAATTCGCTCAACGACAAGGCGGCGTCGAGCATGTTCTGGCAGATCGGCGCCGGACTTCTGGTCGTCGTCC
TCGGCATCGTCGTGATCGCGCTCGCGGCGCGCCGCATTGCCCGGCCGATCGGCAGCTGCGCGGAGTTTGCGGACGGCATC
GCCCGCGGCGATCTCGAGCAGAAACTCGCCATCGAGCAGGCTGATGAAGTCGGCATCCTGGCGAACTCGCTGCGCACCAT
GCAGGGCGAATTGAAGCGCAGCATTGCGCAGCGTGCCGAGGACCAGGCAAATGCCGATGTCACCCGCAAGCGCGCGATGA
ACGAGATGGCCGACAATTTCGAAACTGCTGTCGGTCGGATCGTCGAAACGGTGTCCGCGGCCTCGAGCGAACTCGAATTG
TCCGCAGGCACGCTGGCCTCGACGGCGGAGCGCTCACAGCAACTCACCTCGGTGGTTGCGGCAGCGTCGGAGGAAGCCTC
GACCAACGTCCAGTCGGTCGCCTCCGCGACCGAGGAAATGGCCTCATCCGTCAACGAGATCAGCCGGCAAGTGCAGGATT
CCTCCCGGATTGCCACCGAGGCCGTTGCGCAAGCGCAGCGGACCAACGATCGCGTCGGAGAACTGGCGAAGGCCGCTGCG
CGAATCGGCGACGTCGTCGAATTGATCAATACGATCGCGGGCCAGACCAATCTGCTCGCGCTCAATGCCACGATCGAGGC
GGCGCGCGCCGGCGAGGCCGGCCGCGGCTTCGCCGTGGTGGCCTCCGAGGTCAAGGCTCTGGCCGAACAGACCGCCAAGG
CGACCGGCGAAATCAGCGCCCAGATCGGTGGCATTCAGACCGCGACCGACGAATCGGTGGTGGCGATCAGGGAAATCGGC
GACACCATCGCGCGGATCTCCGAGATCGCTGCAACGATCGCATCTGCCGTCGAAGAGCAGGGCGCCGCCACGCAGGAGAT
TTCCCGCAATGTGCAGGAGGCCTCGCGCGGCACCGCCGAAGTCACGGCGAATGTCGTCAATGTGCAGCGCGGTGCCAGCG
AGACCGGCACCGCCTCGTCACAGGTCCTGGAGGCAGCGAAGTCGCTGTCCGGCGAAAGCAGTCGGCTCAAGCACGAAGTC
GGGCAGTTCCTGAATTCGGTCCGCGCGGCTTAG

Upstream 100 bases:

>100_bases
CCTTGCCTAAAGTCGCAGGCGCACTGGTAGTCGTACCAGCCGTGAAATTTATAACTGCTTCAGTCAGGGAGGTTAAGAAC
GCCCCGACCAGGAGGACGTG

Downstream 100 bases:

>100_bases
TCTCCGGTTCGAGAGACGGACCTCGCTCCGAGCGAAGCCGACTTTCTCTCCCGCATGTGGGGCGGTGACGGCCGCGCCGT
CACCGCCTTGCGGCGATGAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MNFSFRAIKTVQLKIALVSGLCLTGASLMLIVYSIVSAQSTNSYVTTEVMQLVDSQTKESLLNRGSTEAGSIKSELDVGL
DAARTMAHAFAVLADAKNSGTPDSNRRAQLNAVLNNTLKQNPAFNGTYSAWEPNALDGNDAAFKGRQDMGSDTTGRFLPY
WTRGASGAIAVQPLVEYDSSERHPNGLVKGAWFINPQTTGKENILGPLPYIVQGKQVFLATMSVPIMIGGKFVGVAGADY
NLDFVQKLAKQVNASLYDGKGKVAIINNTGLIVANSANDATIGKRAEEADPRWAGSLAIVQSGKGKVLDDPKSKDVEVYS
PINVGSTGTPWSVLISVPRDVVLASAKKLDNSLNDKAASSMFWQIGAGLLVVVLGIVVIALAARRIARPIGSCAEFADGI
ARGDLEQKLAIEQADEVGILANSLRTMQGELKRSIAQRAEDQANADVTRKRAMNEMADNFETAVGRIVETVSAASSELEL
SAGTLASTAERSQQLTSVVAAASEEASTNVQSVASATEEMASSVNEISRQVQDSSRIATEAVAQAQRTNDRVGELAKAAA
RIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISAQIGGIQTATDESVVAIREIG
DTIARISEIAATIASAVEEQGAATQEISRNVQEASRGTAEVTANVVNVQRGASETGTASSQVLEAAKSLSGESSRLKHEV
GQFLNSVRAA

Sequences:

>Translated_730_residues
MNFSFRAIKTVQLKIALVSGLCLTGASLMLIVYSIVSAQSTNSYVTTEVMQLVDSQTKESLLNRGSTEAGSIKSELDVGL
DAARTMAHAFAVLADAKNSGTPDSNRRAQLNAVLNNTLKQNPAFNGTYSAWEPNALDGNDAAFKGRQDMGSDTTGRFLPY
WTRGASGAIAVQPLVEYDSSERHPNGLVKGAWFINPQTTGKENILGPLPYIVQGKQVFLATMSVPIMIGGKFVGVAGADY
NLDFVQKLAKQVNASLYDGKGKVAIINNTGLIVANSANDATIGKRAEEADPRWAGSLAIVQSGKGKVLDDPKSKDVEVYS
PINVGSTGTPWSVLISVPRDVVLASAKKLDNSLNDKAASSMFWQIGAGLLVVVLGIVVIALAARRIARPIGSCAEFADGI
ARGDLEQKLAIEQADEVGILANSLRTMQGELKRSIAQRAEDQANADVTRKRAMNEMADNFETAVGRIVETVSAASSELEL
SAGTLASTAERSQQLTSVVAAASEEASTNVQSVASATEEMASSVNEISRQVQDSSRIATEAVAQAQRTNDRVGELAKAAA
RIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISAQIGGIQTATDESVVAIREIG
DTIARISEIAATIASAVEEQGAATQEISRNVQEASRGTAEVTANVVNVQRGASETGTASSQVLEAAKSLSGESSRLKHEV
GQFLNSVRAA
>Mature_730_residues
MNFSFRAIKTVQLKIALVSGLCLTGASLMLIVYSIVSAQSTNSYVTTEVMQLVDSQTKESLLNRGSTEAGSIKSELDVGL
DAARTMAHAFAVLADAKNSGTPDSNRRAQLNAVLNNTLKQNPAFNGTYSAWEPNALDGNDAAFKGRQDMGSDTTGRFLPY
WTRGASGAIAVQPLVEYDSSERHPNGLVKGAWFINPQTTGKENILGPLPYIVQGKQVFLATMSVPIMIGGKFVGVAGADY
NLDFVQKLAKQVNASLYDGKGKVAIINNTGLIVANSANDATIGKRAEEADPRWAGSLAIVQSGKGKVLDDPKSKDVEVYS
PINVGSTGTPWSVLISVPRDVVLASAKKLDNSLNDKAASSMFWQIGAGLLVVVLGIVVIALAARRIARPIGSCAEFADGI
ARGDLEQKLAIEQADEVGILANSLRTMQGELKRSIAQRAEDQANADVTRKRAMNEMADNFETAVGRIVETVSAASSELEL
SAGTLASTAERSQQLTSVVAAASEEASTNVQSVASATEEMASSVNEISRQVQDSSRIATEAVAQAQRTNDRVGELAKAAA
RIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISAQIGGIQTATDESVVAIREIG
DTIARISEIAATIASAVEEQGAATQEISRNVQEASRGTAEVTANVVNVQRGASETGTASSQVLEAAKSLSGESSRLKHEV
GQFLNSVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=337, Percent_Identity=31.4540059347181, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787690, Length=374, Percent_Identity=28.3422459893048, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1788194, Length=376, Percent_Identity=27.9255319148936, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788195, Length=304, Percent_Identity=30.5921052631579, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1789453, Length=336, Percent_Identity=27.9761904761905, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76470; Mature: 76470

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSFRAIKTVQLKIALVSGLCLTGASLMLIVYSIVSAQSTNSYVTTEVMQLVDSQTKES
CCCCCEEHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LLNRGSTEAGSIKSELDVGLDAARTMAHAFAVLADAKNSGTPDSNRRAQLNAVLNNTLKQ
HHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
NPAFNGTYSAWEPNALDGNDAAFKGRQDMGSDTTGRFLPYWTRGASGAIAVQPLVEYDSS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEECCCCCCEEECHHHHCCCC
ERHPNGLVKGAWFINPQTTGKENILGPLPYIVQGKQVFLATMSVPIMIGGKFVGVAGADY
CCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCEEEEEEECCCEEECCEEEEECCCCC
NLDFVQKLAKQVNASLYDGKGKVAIINNTGLIVANSANDATIGKRAEEADPRWAGSLAIV
CHHHHHHHHHHHCCEEECCCCCEEEEECCCEEEECCCCCCHHCCCCHHCCCCCCCCEEEE
QSGKGKVLDDPKSKDVEVYSPINVGSTGTPWSVLISVPRDVVLASAKKLDNSLNDKAASS
ECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
MFWQIGAGLLVVVLGIVVIALAARRIARPIGSCAEFADGIARGDLEQKLAIEQADEVGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ANSLRTMQGELKRSIAQRAEDQANADVTRKRAMNEMADNFETAVGRIVETVSAASSELEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SAGTLASTAERSQQLTSVVAAASEEASTNVQSVASATEEMASSVNEISRQVQDSSRIATE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAQAQRTNDRVGELAKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHHHH
ASEVKALAEQTAKATGEISAQIGGIQTATDESVVAIREIGDTIARISEIAATIASAVEEQ
HHHHHHHHHHHHHHHCHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATQEISRNVQEASRGTAEVTANVVNVQRGASETGTASSQVLEAAKSLSGESSRLKHEV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GQFLNSVRAA
HHHHHHHCCC
>Mature Secondary Structure
MNFSFRAIKTVQLKIALVSGLCLTGASLMLIVYSIVSAQSTNSYVTTEVMQLVDSQTKES
CCCCCEEHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LLNRGSTEAGSIKSELDVGLDAARTMAHAFAVLADAKNSGTPDSNRRAQLNAVLNNTLKQ
HHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
NPAFNGTYSAWEPNALDGNDAAFKGRQDMGSDTTGRFLPYWTRGASGAIAVQPLVEYDSS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEECCCCCCEEECHHHHCCCC
ERHPNGLVKGAWFINPQTTGKENILGPLPYIVQGKQVFLATMSVPIMIGGKFVGVAGADY
CCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCEEEEEEECCCEEECCEEEEECCCCC
NLDFVQKLAKQVNASLYDGKGKVAIINNTGLIVANSANDATIGKRAEEADPRWAGSLAIV
CHHHHHHHHHHHCCEEECCCCCEEEEECCCEEEECCCCCCHHCCCCHHCCCCCCCCEEEE
QSGKGKVLDDPKSKDVEVYSPINVGSTGTPWSVLISVPRDVVLASAKKLDNSLNDKAASS
ECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHH
MFWQIGAGLLVVVLGIVVIALAARRIARPIGSCAEFADGIARGDLEQKLAIEQADEVGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ANSLRTMQGELKRSIAQRAEDQANADVTRKRAMNEMADNFETAVGRIVETVSAASSELEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SAGTLASTAERSQQLTSVVAAASEEASTNVQSVASATEEMASSVNEISRQVQDSSRIATE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAQAQRTNDRVGELAKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCHHHH
ASEVKALAEQTAKATGEISAQIGGIQTATDESVVAIREIGDTIARISEIAATIASAVEEQ
HHHHHHHHHHHHHHHCHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATQEISRNVQEASRGTAEVTANVVNVQRGASETGTASSQVLEAAKSLSGESSRLKHEV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GQFLNSVRAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]