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The map label for this gene is fmdA [H]

Identifier: 86748382

GI number: 86748382

Start: 1438572

End: 1439801

Strand: Direct

Name: fmdA [H]

Synonym: RPB_1257

Alternate gene names: 86748382

Gene position: 1438572-1439801 (Clockwise)

Preceding gene: 86748381

Following gene: 86748383

Centisome position: 26.98

GC content: 64.15

Gene sequence:

>1230_bases
ATGCCAGAGACACTGATCAAGGTCGATCTCACGCAGTCCGCCTACGACAACGAGATGGTCCACAACCGCTGGCACCCGGA
CATTCCGATGGCGGCGTGGGTCAATCCCGGCGACGACTTCATCGTCGAGACCTACGACTGGACCGGCGGCTTCATCAAGA
ACAACGACAGCGCCGACGACGTCCGCGATATCGACCTGTCGATCGTGCACTTCCTGTCGGGGCCGATCGGCGTCAAGGGC
GCCGAGCCGGGCGACCTGCTGGTGGTCGACCTGCTCGACGTCGGCCCGATGAAGGAGAGCCTGTGGGGCTTCAACGGCTT
CTTCTCCAAGCAGAACGGCGGCGGCTTCCTGACCGATCACTTCCCGCTGGCGCAGAAGTCGATCTGGGACTTCAAGGGCA
TGTACACCTCGTCGCGCCACATCCCGGGCGTGAACTTCGCCGGCCTGATCCATCCCGGCCTGATCGGCTGTCTGCCGGAT
CCGAAGCTGCTCGCAACCTGGAACGAGCGCGAGACCGGCCTGATCGCCACCAACCCGACCCGCGTGCCCGGCCTCGCCAA
TCCGCCGTTCGGCCCGACCGCGCATATGGGCAAGCTCACCGGCGACGCCAAGGCGAAAGCCGGAGCGGAAGGCGCCCGCA
CCGTGCCGCCGCGCGAGCACGGCGGCAATTGCGACATCAAGGACCTGTCGCGCGGCTCCAAGATCTTCTTCCCGGTCTAT
GTGCCGGGCGGCGGCCTGTCGATGGGCGACCTGCATTTCAGCCAGGGCGACGGCGAGATCACCTTCTGCGGCGCCATCGA
GATGGCCGGCTGGCTGCACATCAAGGTCGACATCATCAAGGACGGCGTCTCGAAATACGGCATCAAGAATCCGATCTTCA
AGCCGTCGCCGGTGACGCCGAACTACAAGGACTATCTGATCTTCGAAGGCATCTCGGTCGACGAGCAGGGCCAGCAGCAT
TATCTCGACGTCACCGTCGCGTATCGCCAGGCCTGCCTGAACGCCATCGAGTATCTGAAGAAGTTCGGCTACTCCGGCGC
CCAGGCCTATTCGATCCTCGGCACCGCCCCGGTGCAGGGCCACATCTCCGGCGTCGTCGACGTCCCCAACGCCTGCGCCA
CGCTGTGGCTGCCGACCGAGATCTTCGATTTCGACATGATGCCGTCCTCGGCCGGCCCGGTCAAACACATCAAGGGCGAC
ATCCAGATGCCGATCTCGCAGGACAAGTAA

Upstream 100 bases:

>100_bases
CGAGCCGCGCGCCAGCGTCGACGAGGCGCAGGTCGCCAAATATCTGTCCGTCTGAGTCTGTCTATCTAACCGAGTCAACT
GGTAACAAGGGGAGCTTCCG

Downstream 100 bases:

>100_bases
TTGCGTTCGAGTCGGGGTGACCACCTTTCCCCGTCATTGCGAGGAGCGAAGCGACGAAGCAATCCAGAGGCTCAGTGCAC
CGCGCTGGATTGCTTCGCTT

Product: formamidase

Products: NA

Alternate protein names: Formamide amidohydrolase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPETLIKVDLTQSAYDNEMVHNRWHPDIPMAAWVNPGDDFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVKG
AEPGDLLVVDLLDVGPMKESLWGFNGFFSKQNGGGFLTDHFPLAQKSIWDFKGMYTSSRHIPGVNFAGLIHPGLIGCLPD
PKLLATWNERETGLIATNPTRVPGLANPPFGPTAHMGKLTGDAKAKAGAEGARTVPPREHGGNCDIKDLSRGSKIFFPVY
VPGGGLSMGDLHFSQGDGEITFCGAIEMAGWLHIKVDIIKDGVSKYGIKNPIFKPSPVTPNYKDYLIFEGISVDEQGQQH
YLDVTVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDVPNACATLWLPTEIFDFDMMPSSAGPVKHIKGD
IQMPISQDK

Sequences:

>Translated_409_residues
MPETLIKVDLTQSAYDNEMVHNRWHPDIPMAAWVNPGDDFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVKG
AEPGDLLVVDLLDVGPMKESLWGFNGFFSKQNGGGFLTDHFPLAQKSIWDFKGMYTSSRHIPGVNFAGLIHPGLIGCLPD
PKLLATWNERETGLIATNPTRVPGLANPPFGPTAHMGKLTGDAKAKAGAEGARTVPPREHGGNCDIKDLSRGSKIFFPVY
VPGGGLSMGDLHFSQGDGEITFCGAIEMAGWLHIKVDIIKDGVSKYGIKNPIFKPSPVTPNYKDYLIFEGISVDEQGQQH
YLDVTVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDVPNACATLWLPTEIFDFDMMPSSAGPVKHIKGD
IQMPISQDK
>Mature_408_residues
PETLIKVDLTQSAYDNEMVHNRWHPDIPMAAWVNPGDDFIVETYDWTGGFIKNNDSADDVRDIDLSIVHFLSGPIGVKGA
EPGDLLVVDLLDVGPMKESLWGFNGFFSKQNGGGFLTDHFPLAQKSIWDFKGMYTSSRHIPGVNFAGLIHPGLIGCLPDP
KLLATWNERETGLIATNPTRVPGLANPPFGPTAHMGKLTGDAKAKAGAEGARTVPPREHGGNCDIKDLSRGSKIFFPVYV
PGGGLSMGDLHFSQGDGEITFCGAIEMAGWLHIKVDIIKDGVSKYGIKNPIFKPSPVTPNYKDYLIFEGISVDEQGQQHY
LDVTVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQGHISGVVDVPNACATLWLPTEIFDFDMMPSSAGPVKHIKGDI
QMPISQDK

Specific function: Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. Also acts, more slowly, on acetamide, propanamide and butanamide [H]

COG id: COG2421

COG function: function code C; Predicted acetamidase/formamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetamidase/formamidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004304 [H]

Pfam domain/function: PF03069 FmdA_AmdA [H]

EC number: =3.5.1.49 [H]

Molecular weight: Translated: 44431; Mature: 44300

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETLIKVDLTQSAYDNEMVHNRWHPDIPMAAWVNPGDDFIVETYDWTGGFIKNNDSADD
CCCCEEEEEECCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCC
VRDIDLSIVHFLSGPIGVKGAEPGDLLVVDLLDVGPMKESLWGFNGFFSKQNGGGFLTDH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCEEECCCCCCEEECC
FPLAQKSIWDFKGMYTSSRHIPGVNFAGLIHPGLIGCLPDPKLLATWNERETGLIATNPT
CCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCEEEEECCCCCCEEEECCC
RVPGLANPPFGPTAHMGKLTGDAKAKAGAEGARTVPPREHGGNCDIKDLSRGSKIFFPVY
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEE
VPGGGLSMGDLHFSQGDGEITFCGAIEMAGWLHIKVDIIKDGVSKYGIKNPIFKPSPVTP
ECCCCCCCCCEEEECCCCCEEEEEEEEECCEEEEEEEEECCCHHHCCCCCCCCCCCCCCC
NYKDYLIFEGISVDEQGQQHYLDVTVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQG
CCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
HISGVVDVPNACATLWLPTEIFDFDMMPSSAGPVKHIKGDIQMPISQDK
CCEEEEECCCCCEEEEECHHHEEEECCCCCCCCHHHCCCCEECCCCCCC
>Mature Secondary Structure 
PETLIKVDLTQSAYDNEMVHNRWHPDIPMAAWVNPGDDFIVETYDWTGGFIKNNDSADD
CCCEEEEEECCCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCEEECCCCCCC
VRDIDLSIVHFLSGPIGVKGAEPGDLLVVDLLDVGPMKESLWGFNGFFSKQNGGGFLTDH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCEEECCCCCCEEECC
FPLAQKSIWDFKGMYTSSRHIPGVNFAGLIHPGLIGCLPDPKLLATWNERETGLIATNPT
CCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCEEEEECCCCCCEEEECCC
RVPGLANPPFGPTAHMGKLTGDAKAKAGAEGARTVPPREHGGNCDIKDLSRGSKIFFPVY
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEE
VPGGGLSMGDLHFSQGDGEITFCGAIEMAGWLHIKVDIIKDGVSKYGIKNPIFKPSPVTP
ECCCCCCCCCEEEECCCCCEEEEEEEEECCEEEEEEEEECCCHHHCCCCCCCCCCCCCCC
NYKDYLIFEGISVDEQGQQHYLDVTVAYRQACLNAIEYLKKFGYSGAQAYSILGTAPVQG
CCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
HISGVVDVPNACATLWLPTEIFDFDMMPSSAGPVKHIKGDIQMPISQDK
CCEEEEECCCCCEEEEECHHHEEEECCCCCCCCHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841393 [H]