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The map label for this gene is nudL [H]

Identifier: 86748319

GI number: 86748319

Start: 1370308

End: 1370973

Strand: Direct

Name: nudL [H]

Synonym: RPB_1194

Alternate gene names: 86748319

Gene position: 1370308-1370973 (Clockwise)

Preceding gene: 86748318

Following gene: 86748320

Centisome position: 25.7

GC content: 63.96

Gene sequence:

>666_bases
ATGATGGGGATTGAGTCTGCCCCGGGCAGCATCAGTTCGGCCGACTTCTTCGATCGCGCCCTGCGACGATTGCGGTTCGA
CGTGCCGCCGGCGCTGACGGACGCCAGCGTCATTCCCGAGAGCGGCGATCACGGCACCGACCGGATGCTGCGTCTGATCG
CGCAGGAACGGCCGATCCGTCCGGCTGCGGTGCTGATCCCGGTGATCGAGCACGCCGAACCGACCGTGCTGCTGACGATG
CGCGCTGCGCATCTCAACGATCATGCCGGGCAGATCGCGTTTCCTGGCGGCAAGATCGACGCCGCCGACAATTCGCCACT
CGACGCGGCTCTGCGCGAGGCGGAGGAAGAGATCGGTCTCGACCGCTCCTATGTCGAGCCGATCGGCTATCTCGACGTCT
ACGGCACCGGCTTCGGCTTTCGCATCCTGCCAACGGTGGCGCGGGTGCGGCCCGGCTTCGAACTGACCATCAACAAATCG
GAAGTCGACGACGCTTTCGAGGTGCCGCTGTCGTTTCTGATGAATCCGGGCAATCACCAATTGCACAGCAAGGAATTCCG
CGGCGCGCTGCGCTCGTATTATGCGATGCCGTTCGCCGAACGTTACATCTGGGGCGCGACAGCGGGGATCCTGCGGCTCA
TGTACGAACGGATCTGCCTGCCATGA

Upstream 100 bases:

>100_bases
AAGTTTGGAATTGCTTCCGGCGGCGCATTCTTCGCGATGGCCGACGCGGAGCAGATGAGGGAAGCACTTTGAACGGGCCG
GAACCACTTTGAACGAGCCG

Downstream 100 bases:

>100_bases
TCCGTGCCATCTTGACTGAAGTCGCGATCTTTCTCATCCCCTTCATTGCCTACGCGATCTACCTGGTCGTCACGCGTGCG
GCGCTGACGCATCGTTCGTC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MMGIESAPGSISSADFFDRALRRLRFDVPPALTDASVIPESGDHGTDRMLRLIAQERPIRPAAVLIPVIEHAEPTVLLTM
RAAHLNDHAGQIAFPGGKIDAADNSPLDAALREAEEEIGLDRSYVEPIGYLDVYGTGFGFRILPTVARVRPGFELTINKS
EVDDAFEVPLSFLMNPGNHQLHSKEFRGALRSYYAMPFAERYIWGATAGILRLMYERICLP

Sequences:

>Translated_221_residues
MMGIESAPGSISSADFFDRALRRLRFDVPPALTDASVIPESGDHGTDRMLRLIAQERPIRPAAVLIPVIEHAEPTVLLTM
RAAHLNDHAGQIAFPGGKIDAADNSPLDAALREAEEEIGLDRSYVEPIGYLDVYGTGFGFRILPTVARVRPGFELTINKS
EVDDAFEVPLSFLMNPGNHQLHSKEFRGALRSYYAMPFAERYIWGATAGILRLMYERICLP
>Mature_221_residues
MMGIESAPGSISSADFFDRALRRLRFDVPPALTDASVIPESGDHGTDRMLRLIAQERPIRPAAVLIPVIEHAEPTVLLTM
RAAHLNDHAGQIAFPGGKIDAADNSPLDAALREAEEEIGLDRSYVEPIGYLDVYGTGFGFRILPTVARVRPGFELTINKS
EVDDAFEVPLSFLMNPGNHQLHSKEFRGALRSYYAMPFAERYIWGATAGILRLMYERICLP

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=126, Percent_Identity=34.1269841269841, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788115, Length=153, Percent_Identity=39.8692810457516, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536993, Length=167, Percent_Identity=30.5389221556886, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859683, Length=214, Percent_Identity=36.4485981308411, Blast_Score=87, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 24436; Mature: 24436

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGIESAPGSISSADFFDRALRRLRFDVPPALTDASVIPESGDHGTDRMLRLIAQERPIR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PAAVLIPVIEHAEPTVLLTMRAAHLNDHAGQIAFPGGKIDAADNSPLDAALREAEEEIGL
CHHHHHHHHHCCCCEEEEEEEHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHCC
DRSYVEPIGYLDVYGTGFGFRILPTVARVRPGFELTINKSEVDDAFEVPLSFLMNPGNHQ
CHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECHHHCCHHHHHHHHHHCCCCCCC
LHSKEFRGALRSYYAMPFAERYIWGATAGILRLMYERICLP
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMGIESAPGSISSADFFDRALRRLRFDVPPALTDASVIPESGDHGTDRMLRLIAQERPIR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PAAVLIPVIEHAEPTVLLTMRAAHLNDHAGQIAFPGGKIDAADNSPLDAALREAEEEIGL
CHHHHHHHHHCCCCEEEEEEEHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHCC
DRSYVEPIGYLDVYGTGFGFRILPTVARVRPGFELTINKSEVDDAFEVPLSFLMNPGNHQ
CHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECHHHCCHHHHHHHHHHCCCCCCC
LHSKEFRGALRSYYAMPFAERYIWGATAGILRLMYERICLP
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA