Click here to switch to the map view.

The map label for this gene is plsC [C]

Identifier: 86747963

GI number: 86747963

Start: 951532

End: 952341

Strand: Direct

Name: plsC [C]

Synonym: RPB_0837

Alternate gene names: 86747963

Gene position: 951532-952341 (Clockwise)

Preceding gene: 86747962

Following gene: 86747965

Centisome position: 17.85

GC content: 63.33

Gene sequence:

>810_bases
ATGACGAGCATTTTCGTCCGTTCGTTGATTTTCAACGTGCTGTTCTATCTGCTGCTGGTGTTCTGGATTCTGGTCGCGGT
GCCGACCTTCGTGCTGCCGCGCCGCGCGCTGATCGGGGTCGCCAAGCTGTGGGGCCGGAGCAGCATCTGGCTGATGCGTG
TCGTCTGCAACACCAGGGTCGAATTCCGCGGCCTCGAGAAGATCCCGCAGGGCCCGCTGATCGTCGCGCCCAAGCATCAG
TCGATGTGGGAGACCTTCGCGTTGCTGCAGTTCTTCGACGCGCCGCTGTACATCTTGAAGCGCGAACTGACCTGGATTCC
GTTCTTCGGCTGGTTTCTGATCAAGGCCGACATGATCGCGATCAACCGCAAGAAGGGCGGACGCATTCTGATGGAGATGG
CGCGCCGCGCCAGCGAGGAGGTCAATCGCGGCCGGCAATTGATCATCTTCCCGGAAGGCACCCGCACCGCGGTCGGCGCG
CCGCCGCACTACAAGGCCGGCGTCGCCCAGATCTATGTCGACTGCGACGTGCCGTGCCTGCCGGTGGCGCTGAATTCCGG
ACTGTTCTGGCCGCGCCGCCAGTTCATGCGCTACCCGGGCACGATCGTCGTCGAATTTCTCGATCCCTTGCCGGTCGGCC
TGACGCGGCGGGAATTCATCGACACCGTCAGCGAGCTGATCGAGACAGCCAGCAACCGGCTGATCGAAGCCGGTCGCAAG
GAGCAGGCCGAGCTGTTCGGTCGGGTGCCGAGCGCGAACGTCCCGGCTGCCGCACCGACAGTGGCCAAGCGCAATATCGG
CAATCAGTAA

Upstream 100 bases:

>100_bases
CGACTGGGCATCGACATCATGCCCGAAGCCGCCGAGCAGTCGCCCGAGTCGGTGGCCCACAAACCGGCGACGGCGCTCGC
CAACTGACCGGATCGTTTCG

Downstream 100 bases:

>100_bases
TCCACGCCACAACAAGCCGCAGCCTGCCCCCTCTCCCGCTTGCGGGAGAGGGCTGGGGTGAGGGCGAGCCGAGCACGGTC
TCTGCGATTCGCCGAGAGCC

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Phospholipids Biosynthesis-Related Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTSIFVRSLIFNVLFYLLLVFWILVAVPTFVLPRRALIGVAKLWGRSSIWLMRVVCNTRVEFRGLEKIPQGPLIVAPKHQ
SMWETFALLQFFDAPLYILKRELTWIPFFGWFLIKADMIAINRKKGGRILMEMARRASEEVNRGRQLIIFPEGTRTAVGA
PPHYKAGVAQIYVDCDVPCLPVALNSGLFWPRRQFMRYPGTIVVEFLDPLPVGLTRREFIDTVSELIETASNRLIEAGRK
EQAELFGRVPSANVPAAAPTVAKRNIGNQ

Sequences:

>Translated_269_residues
MTSIFVRSLIFNVLFYLLLVFWILVAVPTFVLPRRALIGVAKLWGRSSIWLMRVVCNTRVEFRGLEKIPQGPLIVAPKHQ
SMWETFALLQFFDAPLYILKRELTWIPFFGWFLIKADMIAINRKKGGRILMEMARRASEEVNRGRQLIIFPEGTRTAVGA
PPHYKAGVAQIYVDCDVPCLPVALNSGLFWPRRQFMRYPGTIVVEFLDPLPVGLTRREFIDTVSELIETASNRLIEAGRK
EQAELFGRVPSANVPAAAPTVAKRNIGNQ
>Mature_268_residues
TSIFVRSLIFNVLFYLLLVFWILVAVPTFVLPRRALIGVAKLWGRSSIWLMRVVCNTRVEFRGLEKIPQGPLIVAPKHQS
MWETFALLQFFDAPLYILKRELTWIPFFGWFLIKADMIAINRKKGGRILMEMARRASEEVNRGRQLIIFPEGTRTAVGAP
PHYKAGVAQIYVDCDVPCLPVALNSGLFWPRRQFMRYPGTIVVEFLDPLPVGLTRREFIDTVSELIETASNRLIEAGRKE
QAELFGRVPSANVPAAAPTVAKRNIGNQ

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI15100175, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641614, Length=249, Percent_Identity=29.3172690763052, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641612, Length=249, Percent_Identity=29.3172690763052, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 30570; Mature: 30438

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIFVRSLIFNVLFYLLLVFWILVAVPTFVLPRRALIGVAKLWGRSSIWLMRVVCNTRV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
EFRGLEKIPQGPLIVAPKHQSMWETFALLQFFDAPLYILKRELTWIPFFGWFLIKADMIA
HCCCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHE
INRKKGGRILMEMARRASEEVNRGRQLIIFPEGTRTAVGAPPHYKAGVAQIYVDCDVPCL
EECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
PVALNSGLFWPRRQFMRYPGTIVVEFLDPLPVGLTRREFIDTVSELIETASNRLIEAGRK
HHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
EQAELFGRVPSANVPAAAPTVAKRNIGNQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TSIFVRSLIFNVLFYLLLVFWILVAVPTFVLPRRALIGVAKLWGRSSIWLMRVVCNTRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
EFRGLEKIPQGPLIVAPKHQSMWETFALLQFFDAPLYILKRELTWIPFFGWFLIKADMIA
HCCCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHE
INRKKGGRILMEMARRASEEVNRGRQLIIFPEGTRTAVGAPPHYKAGVAQIYVDCDVPCL
EECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
PVALNSGLFWPRRQFMRYPGTIVVEFLDPLPVGLTRREFIDTVSELIETASNRLIEAGRK
HHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
EQAELFGRVPSANVPAAAPTVAKRNIGNQ
HHHHHHCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA