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The map label for this gene is norM [H]

Identifier: 86747922

GI number: 86747922

Start: 893897

End: 895351

Strand: Direct

Name: norM [H]

Synonym: RPB_0796

Alternate gene names: 86747922

Gene position: 893897-895351 (Clockwise)

Preceding gene: 86747918

Following gene: 86747929

Centisome position: 16.77

GC content: 71.27

Gene sequence:

>1455_bases
ATGTCCGACATCGCCGTCGCCGAACTGCCGCCGGTGCAGGGCGACCCGCCGCCGCGGCGCGACGCCGAACCGCCGCTGCC
GCCGCCCAATCCGCTGCTCGACGGCGCCATCCTGCCGACGCTGTTGCGGCTGTCCTGGCCGAATGTGGTGGCGCTGACCG
CCGGCACCTGCGTGGTGGTCGCCGAGACCTCCTATATCGGCCGGCTCGGCACCGAGGCGCTGGCGGCGATGGCGCTGGTG
TTTCCGTTCGTGATCCTGACCATGACGATGTCCGGCGGCGCGATGGGTGGCGGCGTCGCCTCGGCGGTGTCGCGCGCGCT
CGGTTCCGGCGACAGCGACCGCGCCGCCACGCTGGCGATGCATGCGCTGCTGATCGGGCTGTGCTTCGGCCTGGTGTTCA
CGGTGGGGATGCTGACATTCGGCGATACAGCGCTGGCGCTGCTCGGCGGCCGCGGCAATGTGCTGGCGCAGGCGGTGAGC
TACGCCCACATCTTCTTCGCCGGCGCGGTGGTGCCGTGGCTGATGAACACCTTCGCGGCGATCCTGCGCGGCACCGGCAA
CATGAAGCTGCCGTCGCTGATGATCCTGACGGCGGCCGGGCTGCAGATCGTGCTCGGCGGCGTGCTCGGCCTCGGCTTCG
GGCCGGTCCCGCGTTTCGGCATGCCGGGCGTCGCCGCCGGCACGCTGACGGCGTTCTCGGTCGGCGCCGGGGTGATGGCC
TGGTACATCTTCTCCGGCCGCGCCGGCGTGACGCCGAAATTCAAGGGGCTGCGGATCCAGCGCGCGATGTTCTTCGACAT
TCTCAAGGTCGGCGCGGTGGCCTGCTTCACGCCGCTGCAGTCGGTGCTGACGATCACCATCTTCACCCACATGCTGGCGC
GCTTCGGCACCGAGATCCTCGCCGGCTACGGCATCGGCGCGCGGCTGGAATTCATGCTGACCTCGATCGCCTTCGCGGTC
GGCATCGCCTCGGTGCCGATGATCGGCATGGCGATCGGCGCCGGCCGGGTGGCGCGCGCGCGGCGGATCGCCTGGACCGC
GGCGCTGGTGTCGTTTCTCTGCGTCGGCGTGGTCGGCAGCGCGGTCGCCTTCTTCCCGCATCTGTGGGTCGATCTGTTCA
CCAGCGACCCGGGCGTCAAGCTCGCCGGCGAGCGCTATCTGCGGGCGGCGGGGCCGATGTACGCCTTCATCGGCCTGTCG
ATCTCGTTGTATTTCTCGGCGCAGGGCGCCGCGCGGGTGCTGGGGCCGGTGCTGGCGCAGACCGGGCGGCTGATCTTCGT
CGTCCTCGGCGGCTGGCTGCTCATCGCCCACAACGGCAGCGTCGGCCATTTCTTCGCGCTCGCCGCCGCCTCGATGGGCG
TGCTCGGCCTCGCCACCGCGCTCGCCGTGCTGCTGACGCGCTGGTCGCCGAAGCAGGTCGCGGTGACGGACGCGGGATCA
CCGCCGCCGGGCTGA

Upstream 100 bases:

>100_bases
TGTGCCAAGGGCCCCATGCGTTGCGCGGGCATCGCTTTGCCGCGGAACGATGATAGGAACGGATCGAGGCCGGCAGATCA
GATCGGGCCCGGGGGGAACC

Downstream 100 bases:

>100_bases
CGCGCGATCAGCCGTCGCTGCGCTCCAGCGTCGTCCGCATCGCCGCGACGCCGAGCTGCATTTGCGCGGCGATCATCGGG
GCGATCGCATCCGGCAGCAG

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSDIAVAELPPVQGDPPPRRDAEPPLPPPNPLLDGAILPTLLRLSWPNVVALTAGTCVVVAETSYIGRLGTEALAAMALV
FPFVILTMTMSGGAMGGGVASAVSRALGSGDSDRAATLAMHALLIGLCFGLVFTVGMLTFGDTALALLGGRGNVLAQAVS
YAHIFFAGAVVPWLMNTFAAILRGTGNMKLPSLMILTAAGLQIVLGGVLGLGFGPVPRFGMPGVAAGTLTAFSVGAGVMA
WYIFSGRAGVTPKFKGLRIQRAMFFDILKVGAVACFTPLQSVLTITIFTHMLARFGTEILAGYGIGARLEFMLTSIAFAV
GIASVPMIGMAIGAGRVARARRIAWTAALVSFLCVGVVGSAVAFFPHLWVDLFTSDPGVKLAGERYLRAAGPMYAFIGLS
ISLYFSAQGAARVLGPVLAQTGRLIFVVLGGWLLIAHNGSVGHFFALAAASMGVLGLATALAVLLTRWSPKQVAVTDAGS
PPPG

Sequences:

>Translated_484_residues
MSDIAVAELPPVQGDPPPRRDAEPPLPPPNPLLDGAILPTLLRLSWPNVVALTAGTCVVVAETSYIGRLGTEALAAMALV
FPFVILTMTMSGGAMGGGVASAVSRALGSGDSDRAATLAMHALLIGLCFGLVFTVGMLTFGDTALALLGGRGNVLAQAVS
YAHIFFAGAVVPWLMNTFAAILRGTGNMKLPSLMILTAAGLQIVLGGVLGLGFGPVPRFGMPGVAAGTLTAFSVGAGVMA
WYIFSGRAGVTPKFKGLRIQRAMFFDILKVGAVACFTPLQSVLTITIFTHMLARFGTEILAGYGIGARLEFMLTSIAFAV
GIASVPMIGMAIGAGRVARARRIAWTAALVSFLCVGVVGSAVAFFPHLWVDLFTSDPGVKLAGERYLRAAGPMYAFIGLS
ISLYFSAQGAARVLGPVLAQTGRLIFVVLGGWLLIAHNGSVGHFFALAAASMGVLGLATALAVLLTRWSPKQVAVTDAGS
PPPG
>Mature_483_residues
SDIAVAELPPVQGDPPPRRDAEPPLPPPNPLLDGAILPTLLRLSWPNVVALTAGTCVVVAETSYIGRLGTEALAAMALVF
PFVILTMTMSGGAMGGGVASAVSRALGSGDSDRAATLAMHALLIGLCFGLVFTVGMLTFGDTALALLGGRGNVLAQAVSY
AHIFFAGAVVPWLMNTFAAILRGTGNMKLPSLMILTAAGLQIVLGGVLGLGFGPVPRFGMPGVAAGTLTAFSVGAGVMAW
YIFSGRAGVTPKFKGLRIQRAMFFDILKVGAVACFTPLQSVLTITIFTHMLARFGTEILAGYGIGARLEFMLTSIAFAVG
IASVPMIGMAIGAGRVARARRIAWTAALVSFLCVGVVGSAVAFFPHLWVDLFTSDPGVKLAGERYLRAAGPMYAFIGLSI
SLYFSAQGAARVLGPVLAQTGRLIFVVLGGWLLIAHNGSVGHFFALAAASMGVLGLATALAVLLTRWSPKQVAVTDAGSP
PPG

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=341, Percent_Identity=25.2199413489736, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49784; Mature: 49653

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIAVAELPPVQGDPPPRRDAEPPLPPPNPLLDGAILPTLLRLSWPNVVALTAGTCVVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEE
AETSYIGRLGTEALAAMALVFPFVILTMTMSGGAMGGGVASAVSRALGSGDSDRAATLAM
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
HALLIGLCFGLVFTVGMLTFGDTALALLGGRGNVLAQAVSYAHIFFAGAVVPWLMNTFAA
HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRGTGNMKLPSLMILTAAGLQIVLGGVLGLGFGPVPRFGMPGVAAGTLTAFSVGAGVMA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
WYIFSGRAGVTPKFKGLRIQRAMFFDILKVGAVACFTPLQSVLTITIFTHMLARFGTEIL
HHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYGIGARLEFMLTSIAFAVGIASVPMIGMAIGAGRVARARRIAWTAALVSFLCVGVVGS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFFPHLWVDLFTSDPGVKLAGERYLRAAGPMYAFIGLSISLYFSAQGAARVLGPVLAQ
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHEEECCEEEEEEECCCHHHHHHHHHHH
TGRLIFVVLGGWLLIAHNGSVGHFFALAAASMGVLGLATALAVLLTRWSPKQVAVTDAGS
CCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PPPG
CCCC
>Mature Secondary Structure 
SDIAVAELPPVQGDPPPRRDAEPPLPPPNPLLDGAILPTLLRLSWPNVVALTAGTCVVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEE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CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]