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The map label for this gene is dapB

Identifier: 86747561

GI number: 86747561

Start: 477818

End: 478633

Strand: Direct

Name: dapB

Synonym: RPB_0435

Alternate gene names: 86747561

Gene position: 477818-478633 (Clockwise)

Preceding gene: 86747560

Following gene: 86747565

Centisome position: 8.96

GC content: 67.77

Gene sequence:

>816_bases
ATGTCCGATATGCGCCTGATCGTTGCCGGGGCCGGTGGCCGGATGGGCCGTGCGCTGACGCGCGCCATTTCCGAGACCAA
AGGCGTCGTGCTCACCGGCGCGCTGGAAGCGCCCGGCTCCGAACTGCTGGGCCAGGATGCCGGAGTCCTCGCCGGCCTGC
CCGCCAACGGCGTCGAATTGTCGGCCGATCTATGGACGCTGTCGGCGAACGCCGATGGCATCCTGGATTTCACCGTGCCG
GGCGCGACCATCGCCAATGTGGCGATCGCGGCGCAGCGCGGCATCGTCCATGTGATCGGCACCACCGGCCTGTCGTCCTC
CGACAATGCGGTGATCCAGAGCGTCACCCGGCAGGCCATCGTGGTGAAGTCCGGCAATATGAGCCTCGGCGTCAATCTGC
TGGCGGCGCTGACCAAGCGCGTGGCGCAATCGCTCGGCGACAATTTCGACATCGAGATCGTCGAGATGCACCACCGCGCC
AAGATCGACGCGCCGTCCGGCACCGCGCTGCTGCTCGGCGAAGCCGCCGCCCTGGGCCGTGGCGTCGATCTCGACAGCCA
TTCGGCACGCGGCCGCGACGGCCTCACCGGCGCGCGCAAGACCGGCGATATCGGTTTCGCGTCCTTGCGCGGCGGTACCG
TCACCGGCGATCACAGCGTGATCTTCGCCGGGCCCTATGAGCGGATCGAGCTGGCCCACAAGGCCGAGGACCGCATGATC
TTCGCCCATGGCGCGCTGAAGGCGGCGCAATGGGCGCACGGCAAGAAGCCCGGCCTGTATTCGATGATGGACGTACTCGG
GCTCGCCGAATTCTAG

Upstream 100 bases:

>100_bases
GGCCGCAGCCGCAGGCCTGAGTCGTCTGCCGCTGCTTTCGATCAGTTGCCGGGCCCGGTTCGCCCGGCTATACCGCGGGC
CTGTCAAAGGATCGCAACCG

Downstream 100 bases:

>100_bases
AGCGGTTCACCGACTGATTTGAAACGACGCCGTCTTGTCGAGGGCAGTGTCGTCATCCTGAGGTGCGCGCGCAGCGCGCC
TCGAAGGATGCGGCAGAGGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSDMRLIVAGAGGRMGRALTRAISETKGVVLTGALEAPGSELLGQDAGVLAGLPANGVELSADLWTLSANADGILDFTVP
GATIANVAIAAQRGIVHVIGTTGLSSSDNAVIQSVTRQAIVVKSGNMSLGVNLLAALTKRVAQSLGDNFDIEIVEMHHRA
KIDAPSGTALLLGEAAALGRGVDLDSHSARGRDGLTGARKTGDIGFASLRGGTVTGDHSVIFAGPYERIELAHKAEDRMI
FAHGALKAAQWAHGKKPGLYSMMDVLGLAEF

Sequences:

>Translated_271_residues
MSDMRLIVAGAGGRMGRALTRAISETKGVVLTGALEAPGSELLGQDAGVLAGLPANGVELSADLWTLSANADGILDFTVP
GATIANVAIAAQRGIVHVIGTTGLSSSDNAVIQSVTRQAIVVKSGNMSLGVNLLAALTKRVAQSLGDNFDIEIVEMHHRA
KIDAPSGTALLLGEAAALGRGVDLDSHSARGRDGLTGARKTGDIGFASLRGGTVTGDHSVIFAGPYERIELAHKAEDRMI
FAHGALKAAQWAHGKKPGLYSMMDVLGLAEF
>Mature_270_residues
SDMRLIVAGAGGRMGRALTRAISETKGVVLTGALEAPGSELLGQDAGVLAGLPANGVELSADLWTLSANADGILDFTVPG
ATIANVAIAAQRGIVHVIGTTGLSSSDNAVIQSVTRQAIVVKSGNMSLGVNLLAALTKRVAQSLGDNFDIEIVEMHHRAK
IDAPSGTALLLGEAAALGRGVDLDSHSARGRDGLTGARKTGDIGFASLRGGTVTGDHSVIFAGPYERIELAHKAEDRMIF
AHGALKAAQWAHGKKPGLYSMMDVLGLAEF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=44.9438202247191, Blast_Score=214, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_RHOP2 (Q2J314)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484057.1
- HSSP:   Q9X1K8
- ProteinModelPortal:   Q2J314
- SMR:   Q2J314
- STRING:   Q2J314
- GeneID:   3909991
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0435
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   RPAL316058:RPB_0435-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27824; Mature: 27693

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDMRLIVAGAGGRMGRALTRAISETKGVVLTGALEAPGSELLGQDAGVLAGLPANGVEL
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCEEECCCCCCEEE
SADLWTLSANADGILDFTVPGATIANVAIAAQRGIVHVIGTTGLSSSDNAVIQSVTRQAI
EEEEEEEECCCCCEEEEECCCHHHHHHHEECCCCEEEEEECCCCCCCCHHHHHHHHHEEE
VVKSGNMSLGVNLLAALTKRVAQSLGDNFDIEIVEMHHRAKIDAPSGTALLLGEAAALGR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCEEEEECHHHHCC
GVDLDSHSARGRDGLTGARKTGDIGFASLRGGTVTGDHSVIFAGPYERIELAHKAEDRMI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCCCEEEECCHHHHHHHHCCCCCEE
FAHGALKAAQWAHGKKPGLYSMMDVLGLAEF
EECCCHHHHHHCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SDMRLIVAGAGGRMGRALTRAISETKGVVLTGALEAPGSELLGQDAGVLAGLPANGVEL
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCEEECCCCCCEEE
SADLWTLSANADGILDFTVPGATIANVAIAAQRGIVHVIGTTGLSSSDNAVIQSVTRQAI
EEEEEEEECCCCCEEEEECCCHHHHHHHEECCCCEEEEEECCCCCCCCHHHHHHHHHEEE
VVKSGNMSLGVNLLAALTKRVAQSLGDNFDIEIVEMHHRAKIDAPSGTALLLGEAAALGR
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCEEEEECHHHHCC
GVDLDSHSARGRDGLTGARKTGDIGFASLRGGTVTGDHSVIFAGPYERIELAHKAEDRMI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEECCCCEEEECCHHHHHHHHCCCCCEE
FAHGALKAAQWAHGKKPGLYSMMDVLGLAEF
EECCCHHHHHHCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA