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The map label for this gene is holA

Identifier: 86747513

GI number: 86747513

Start: 429782

End: 430810

Strand: Direct

Name: holA

Synonym: RPB_0387

Alternate gene names: NA

Gene position: 429782-430810 (Clockwise)

Preceding gene: 86747512

Following gene: 86747521

Centisome position: 8.06

GC content: 70.17

Gene sequence:

>1029_bases
ATGGTCGCGCTGCGTGGACGAGACGCCACCTCCTTTCTGGCCCGCCCCGATCCGGGCCGGCCGATCATCCTGCTGTTCGG
CCCCGATGCCGGCCTGGTACGCGAACGCGCCGACGCGCTGATCGCCTCGGCGCTCGACGATCCCAACGACCCGTTCGCGC
TGGTGCGGCTCGACGGCGACGAGCTCGCGGCCGAGCCGTCGCGGCTGGTCGACGAGGCGAATTCGATCCCGATGTTCGGC
GGCCGCCGCGCGATCCGCATCCGCGCCGGCTCGCGCAGCTTCGTCGCCGGCGTCGAGACGCTCGTCGCGTCGCCGCCGAA
GGAATGCCGGATCGTGATCGAGGCCGGCGACATCAAGCCGGACAACGCGCTGCGCAAGGCCTGCGAGAAAGCCGCAAGCG
CGGTGGCGATCGGCTGCTATCCGGACGCCGAGGCCGATCTCGCCAAGCTGATCGACGACGAACTCCGCGCGGCCCAATTG
CAGATCGGCCGCGACGCTCGCGGCGTGCTGATGACGCTGCTCGGCGGCGATCGCCAGGCCTCGCGCAACGAAGTCCGCAA
GCTCGCGCTGTATGCGCACGGCCAGGGCGAGATCACGCTCGACGACGTGATCGCCTGCGTGTCGGACGCCTCCGACCTCA
AGCTCGACGTCATTGTGGATGCGGCGTTCTCCGGCAAGCCGCAGGTCGTCGAAAGCGAATTCGCCAAGGCGATGGTCGCC
GGCACCTATCCGGGGCAGATCATTCTCGCGGCGCAGCGCCACGCCGCGTTCCTGCACAAGACCAGCCTCGCGGTCGACGC
CGGCACGCCGGCCGCGACAGCGCTCGACAGCGGCTTTCCGCGATTGCATTTTTCGCGCAAGGCCGCGTCCGAAACGGCGC
TGCGCAATCTCGGCCCATCGCGCCTGGCGCAGATCATCGACCAGCTCGCCACCGCCGCGCTCGACACGAGACGCCAGGCC
ACCCTCGGCGCCGCCATCGCCCAGCGCACGCTGCTGTCGATCGCGGTAAGCGCGCGGCGAAGGAGTTAG

Upstream 100 bases:

>100_bases
AAATCGCCGAGAACATCAACACCAGGCTGGCGTCGTATTTCTACGCCGGCATCTGAGCCGGTCGTGCGCGCCCGCGCCGC
ATCGCCGGTCTAACATCGCC

Downstream 100 bases:

>100_bases
TTGGGAGGGCGGCGTCGCATCACCGGCCTCGCATCACCGTCATCGTCTCACCGGCATCGTCATCCTGAGGTGCGCGCTCT
TGCGCGCCTCGAAGGATGCG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Subunit; DNA Polymerase III Delta

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVALRGRDATSFLARPDPGRPIILLFGPDAGLVRERADALIASALDDPNDPFALVRLDGDELAAEPSRLVDEANSIPMFG
GRRAIRIRAGSRSFVAGVETLVASPPKECRIVIEAGDIKPDNALRKACEKAASAVAIGCYPDAEADLAKLIDDELRAAQL
QIGRDARGVLMTLLGGDRQASRNEVRKLALYAHGQGEITLDDVIACVSDASDLKLDVIVDAAFSGKPQVVESEFAKAMVA
GTYPGQIILAAQRHAAFLHKTSLAVDAGTPAATALDSGFPRLHFSRKAASETALRNLGPSRLAQIIDQLATAALDTRRQA
TLGAAIAQRTLLSIAVSARRRS

Sequences:

>Translated_342_residues
MVALRGRDATSFLARPDPGRPIILLFGPDAGLVRERADALIASALDDPNDPFALVRLDGDELAAEPSRLVDEANSIPMFG
GRRAIRIRAGSRSFVAGVETLVASPPKECRIVIEAGDIKPDNALRKACEKAASAVAIGCYPDAEADLAKLIDDELRAAQL
QIGRDARGVLMTLLGGDRQASRNEVRKLALYAHGQGEITLDDVIACVSDASDLKLDVIVDAAFSGKPQVVESEFAKAMVA
GTYPGQIILAAQRHAAFLHKTSLAVDAGTPAATALDSGFPRLHFSRKAASETALRNLGPSRLAQIIDQLATAALDTRRQA
TLGAAIAQRTLLSIAVSARRRS
>Mature_342_residues
MVALRGRDATSFLARPDPGRPIILLFGPDAGLVRERADALIASALDDPNDPFALVRLDGDELAAEPSRLVDEANSIPMFG
GRRAIRIRAGSRSFVAGVETLVASPPKECRIVIEAGDIKPDNALRKACEKAASAVAIGCYPDAEADLAKLIDDELRAAQL
QIGRDARGVLMTLLGGDRQASRNEVRKLALYAHGQGEITLDDVIACVSDASDLKLDVIVDAAFSGKPQVVESEFAKAMVA
GTYPGQIILAAQRHAAFLHKTSLAVDAGTPAATALDSGFPRLHFSRKAASETALRNLGPSRLAQIIDQLATAALDTRRQA
TLGAAIAQRTLLSIAVSARRRS

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 36171; Mature: 36171

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALRGRDATSFLARPDPGRPIILLFGPDAGLVRERADALIASALDDPNDPFALVRLDGD
CEEECCCCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
ELAAEPSRLVDEANSIPMFGGRRAIRIRAGSRSFVAGVETLVASPPKECRIVIEAGDIKP
HHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHCEEEEEECCCCC
DNALRKACEKAASAVAIGCYPDAEADLAKLIDDELRAAQLQIGRDARGVLMTLLGGDRQA
CHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCH
SRNEVRKLALYAHGQGEITLDDVIACVSDASDLKLDVIVDAAFSGKPQVVESEFAKAMVA
HHHHHHEEEEEECCCCCEEHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHC
GTYPGQIILAAQRHAAFLHKTSLAVDAGTPAATALDSGFPRLHFSRKAASETALRNLGPS
CCCCCEEEEEEHHHHHHHHHHHEEEECCCCHHHHHHCCCCCEEEHHHHHHHHHHHCCCHH
RLAQIIDQLATAALDTRRQATLGAAIAQRTLLSIAVSARRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVALRGRDATSFLARPDPGRPIILLFGPDAGLVRERADALIASALDDPNDPFALVRLDGD
CEEECCCCCHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
ELAAEPSRLVDEANSIPMFGGRRAIRIRAGSRSFVAGVETLVASPPKECRIVIEAGDIKP
HHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHCEEEEEECCCCC
DNALRKACEKAASAVAIGCYPDAEADLAKLIDDELRAAQLQIGRDARGVLMTLLGGDRQA
CHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCH
SRNEVRKLALYAHGQGEITLDDVIACVSDASDLKLDVIVDAAFSGKPQVVESEFAKAMVA
HHHHHHEEEEEECCCCCEEHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHC
GTYPGQIILAAQRHAAFLHKTSLAVDAGTPAATALDSGFPRLHFSRKAASETALRNLGPS
CCCCCEEEEEEHHHHHHHHHHHEEEECCCCHHHHHHCCCCCEEEHHHHHHHHHHHCCCHH
RLAQIIDQLATAALDTRRQATLGAAIAQRTLLSIAVSARRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA