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The map label for this gene is ftsK [H]

Identifier: 86747503

GI number: 86747503

Start: 416975

End: 419452

Strand: Direct

Name: ftsK [H]

Synonym: RPB_0377

Alternate gene names: 86747503

Gene position: 416975-419452 (Clockwise)

Preceding gene: 86747502

Following gene: 86747504

Centisome position: 7.82

GC content: 68.0

Gene sequence:

>2478_bases
TTGAGCATGCCGGCGATCGAACGCGTCATCCCCCTGGTCGGGCACCTGCCGACATCGCTGCGCGATGCGCTGGCGCGGCG
GCTGCGCGAGCTCGCCGGTTTCGGCCTGATCAGCATCGCCGTCATGGCCGCCGCGGCACTGGCGACCTGGTCGGTGCAGG
ACCCGAGCCTGAGCCACGCCACCTCGCGCAAGATCCACAATCTGATCGGCTATCCCGGCGCGATCGGCGCCGATCTGGCG
ATGCAGATCCTCGGCCTCGGCGCTATCGGCCTGCTGCTGCCGGTCGCGACCTGGGGCTGGCGGATGATCAACCACCGGCC
GTTCGATCGCCGCGCCTTGCGGTTTGGGGCCTGGATTCTCTGCACCATCCTCGCCGCCGGCTTCGCCTCGTCGTTTCCGC
ATGACAGCGCCTGGCCGCTGCCGACCGGCCTCGGCGGCGTGGTCGGCGATGCGCTGGTGCGCGCGCCGTCGCTGATCTTC
GGCCCCGGGCTGATCTTCCGCATCATCCTCAGCATCGTGCTGGGCGGCGCGATGGTGGCGTGCTTCGTGATGGCCAGCGG
CTACGGCTCGCGCGAGCCCGACCCGGTCGAAGCGATCGCCGACGACGTGCCGCTCGACGAAGACGAGGATCGCGACGAGG
GCTCGGTCTCGCTCGGCTGGATGGCCCACGCCGTGCTCTCGGCCAGGGCGCGGCTGTGGCGGCTGATGAAGCTCGGCTAT
CGCGGCCTGGTCAGCAGCGGCGCCTCCGCCGGCCGCTCCGCCGCGGCGTTCGAGCGCCAGGAGCCGAAGCTCGGCAGCGG
CCGGACTTCGCCGCCGATCGTTCCGCGCGACGAGCGCGACGACGACGAGCCGCTCGACCTCGAATCTGCCGATGCGATCG
ACGACGAGGAAGAGGACGAGCCGGTCGCCCGCGCGCCGCGCAAGAAGGCGGCGCCGAAGCCGACGGCGAAAAAGCCCGGC
AAGTTCGAGCTGCCCTCGGTCAACGTGCTGACGGCGCCGAAGGCGTCCGACCGCCAGCCGCTCAACAAGGCCGAGCTCGA
AGCCAATTCGCGCGCGCTGGAAGGCGTGCTGCAGGATTTCGGCGTGCGTGGCGAAATCGTCAAGGCGAACCCCGGCCCGG
TGGTGACGCTGTACGAACTGGAGCCTGCGCCCGGCATCAAATCGTCGCGCGTGATCGGCCTGTCCGACGACATCGCGCGC
TCGATGAGCGCGCTGTCGGCGCGCGTCGCCGTGGTGCCCGGCCGCAACGCGATCGGCATCGAACTGCCCAACGCGCATCG
CGAGAAGGTGTATCTGCGCGAACTGCTCAGCGTGAAGGACGGCAACGAGACCGTGCACAAGCTGCCGCTGTGTCTCGGCA
AGAACATCGGCGGCGATTCGATCATCATCGATCTCGCCCGCACCCCGCATATGCTGATCGCCGGCACCACCGGCTCGGGC
AAATCGGTCGCGATCAACACCATGATCCTCAGCCTGGTGTACCGGCTGCGGCCGGATCAGTGCCGGCTGATCATGGTCGA
TCCGAAGATGCTCGAACTGTCGGTCTATGACGGCATCCCGCATCTCTTGACGCCGGTCGTCACCGATCCGAAGAAGGCGG
TGGTCGCGCTGAAATGGGCGGTGCGCGAGATGGAGGAGCGCTACAAGCGCATGGCCAAGCTCGGCGTCCGCAACATCGAC
GGCTACAATACGCGGCTCTCCGAAGCCAAGGCGCGCGGCGAGGAACTGACCCGTACCGTGCACACCGGCTTCGACAAGGA
AACCGGCAAGGCGATCTACGAGGACGAGAAGCTCGACCTCGAGCCGCTGCCCTACATCGTCATCATCGTCGACGAGATGG
CCGACCTGATGATGGTCGCCGGCAAGGACATCGAAGGCGCGGTGCAGCGGCTGGCCCAGATGGCGCGCGCCGCCGGCCTG
CACGTCATCCTCGCCACGCAGCGGCCCTCGGTCGATGTCATCACCGGCACCATCAAGGCGAACTTCCCGACCCGCATCTC
GTTTCAGGTCACCTCGAAGATCGACAGCCGCACCATCCTGGGCGAAATGGGCGCCGAGCAGCTGCTCGGCCAGGGCGACA
TGCTGTACATGGCCGGCGGCGGCCGCATCTCGCGCGTCCACGGCCCGTTCGTCTCCGACGAGGAAGTCGAGAAGGTCGTC
AAGCATCTCAAGACGCAGGGCCAGCCGGAATATCTCGAGGCGGTCACCGCCGAAGAGCCGGCCGAGGGCGAGGACGGCGC
CGTGTTCGACGCCACCGGCATGGGCGGCGACGGCGGCGGCGACCTGTTCCAGCAGGCGGTCGCCATCGTCAAGCGCGACC
GCAAGGCCTCGACCAGCTATATTCAGCGCCGTCTGCAGATCGGCTACAACCGCGCCGCCTCTCTGATCGAGCGCATGGAA
CTCGAAGGCATCGTCGGCCAGCCCAACCACGCCGGCAAGCGTGAGATCCTGGTGGCCGAAGAAGACTCCGACTTTTGA

Upstream 100 bases:

>100_bases
GCCGGCTACATTCGCGTCGCGATGGTGCAGGACAGTGAGACCACCGCCGAAGCGCTGCACCGTCTGGTGCGGATTCTCGA
GTGAGTCGCGGGGCTGAAAG

Downstream 100 bases:

>100_bases
CCGGCAGGATGATCAGCGTGATGGAATTGTCCGGAGCGGAGTCGCGAAATCGCCACAGCGCCAAGGTAGCCGCTGGGAAG
CTGAGTGCCGGATCCGCCGC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 825; Mature: 824

Protein sequence:

>825_residues
MSMPAIERVIPLVGHLPTSLRDALARRLRELAGFGLISIAVMAAAALATWSVQDPSLSHATSRKIHNLIGYPGAIGADLA
MQILGLGAIGLLLPVATWGWRMINHRPFDRRALRFGAWILCTILAAGFASSFPHDSAWPLPTGLGGVVGDALVRAPSLIF
GPGLIFRIILSIVLGGAMVACFVMASGYGSREPDPVEAIADDVPLDEDEDRDEGSVSLGWMAHAVLSARARLWRLMKLGY
RGLVSSGASAGRSAAAFERQEPKLGSGRTSPPIVPRDERDDDEPLDLESADAIDDEEEDEPVARAPRKKAAPKPTAKKPG
KFELPSVNVLTAPKASDRQPLNKAELEANSRALEGVLQDFGVRGEIVKANPGPVVTLYELEPAPGIKSSRVIGLSDDIAR
SMSALSARVAVVPGRNAIGIELPNAHREKVYLRELLSVKDGNETVHKLPLCLGKNIGGDSIIIDLARTPHMLIAGTTGSG
KSVAINTMILSLVYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKRMAKLGVRNID
GYNTRLSEAKARGEELTRTVHTGFDKETGKAIYEDEKLDLEPLPYIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGL
HVILATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEKVV
KHLKTQGQPEYLEAVTAEEPAEGEDGAVFDATGMGGDGGGDLFQQAVAIVKRDRKASTSYIQRRLQIGYNRAASLIERME
LEGIVGQPNHAGKREILVAEEDSDF

Sequences:

>Translated_825_residues
MSMPAIERVIPLVGHLPTSLRDALARRLRELAGFGLISIAVMAAAALATWSVQDPSLSHATSRKIHNLIGYPGAIGADLA
MQILGLGAIGLLLPVATWGWRMINHRPFDRRALRFGAWILCTILAAGFASSFPHDSAWPLPTGLGGVVGDALVRAPSLIF
GPGLIFRIILSIVLGGAMVACFVMASGYGSREPDPVEAIADDVPLDEDEDRDEGSVSLGWMAHAVLSARARLWRLMKLGY
RGLVSSGASAGRSAAAFERQEPKLGSGRTSPPIVPRDERDDDEPLDLESADAIDDEEEDEPVARAPRKKAAPKPTAKKPG
KFELPSVNVLTAPKASDRQPLNKAELEANSRALEGVLQDFGVRGEIVKANPGPVVTLYELEPAPGIKSSRVIGLSDDIAR
SMSALSARVAVVPGRNAIGIELPNAHREKVYLRELLSVKDGNETVHKLPLCLGKNIGGDSIIIDLARTPHMLIAGTTGSG
KSVAINTMILSLVYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKRMAKLGVRNID
GYNTRLSEAKARGEELTRTVHTGFDKETGKAIYEDEKLDLEPLPYIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGL
HVILATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEKVV
KHLKTQGQPEYLEAVTAEEPAEGEDGAVFDATGMGGDGGGDLFQQAVAIVKRDRKASTSYIQRRLQIGYNRAASLIERME
LEGIVGQPNHAGKREILVAEEDSDF
>Mature_824_residues
SMPAIERVIPLVGHLPTSLRDALARRLRELAGFGLISIAVMAAAALATWSVQDPSLSHATSRKIHNLIGYPGAIGADLAM
QILGLGAIGLLLPVATWGWRMINHRPFDRRALRFGAWILCTILAAGFASSFPHDSAWPLPTGLGGVVGDALVRAPSLIFG
PGLIFRIILSIVLGGAMVACFVMASGYGSREPDPVEAIADDVPLDEDEDRDEGSVSLGWMAHAVLSARARLWRLMKLGYR
GLVSSGASAGRSAAAFERQEPKLGSGRTSPPIVPRDERDDDEPLDLESADAIDDEEEDEPVARAPRKKAAPKPTAKKPGK
FELPSVNVLTAPKASDRQPLNKAELEANSRALEGVLQDFGVRGEIVKANPGPVVTLYELEPAPGIKSSRVIGLSDDIARS
MSALSARVAVVPGRNAIGIELPNAHREKVYLRELLSVKDGNETVHKLPLCLGKNIGGDSIIIDLARTPHMLIAGTTGSGK
SVAINTMILSLVYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWAVREMEERYKRMAKLGVRNIDG
YNTRLSEAKARGEELTRTVHTGFDKETGKAIYEDEKLDLEPLPYIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGLH
VILATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEKVVK
HLKTQGQPEYLEAVTAEEPAEGEDGAVFDATGMGGDGGGDLFQQAVAIVKRDRKASTSYIQRRLQIGYNRAASLIERMEL
EGIVGQPNHAGKREILVAEEDSDF

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=51.2096774193548, Blast_Score=485, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89043; Mature: 88911

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPAIERVIPLVGHLPTSLRDALARRLRELAGFGLISIAVMAAAALATWSVQDPSLSHA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHH
TSRKIHNLIGYPGAIGADLAMQILGLGAIGLLLPVATWGWRMINHRPFDRRALRFGAWIL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
CTILAAGFASSFPHDSAWPLPTGLGGVVGDALVRAPSLIFGPGLIFRIILSIVLGGAMVA
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHH
CFVMASGYGSREPDPVEAIADDVPLDEDEDRDEGSVSLGWMAHAVLSARARLWRLMKLGY
HHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
RGLVSSGASAGRSAAAFERQEPKLGSGRTSPPIVPRDERDDDEPLDLESADAIDDEEEDE
HHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVARAPRKKAAPKPTAKKPGKFELPSVNVLTAPKASDRQPLNKAELEANSRALEGVLQDF
HHHHCCCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVRGEIVKANPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSALSARVAVVPGRNAIGI
CCCCEEEECCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHEEEEECCCCEEEE
ELPNAHREKVYLRELLSVKDGNETVHKLPLCLGKNIGGDSIIIDLARTPHMLIAGTTGSG
ECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCC
KSVAINTMILSLVYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWA
CEEHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHCCCHHHHCCCCCCCHHHHHHHHHH
VREMEERYKRMAKLGVRNIDGYNTRLSEAKARGEELTRTVHTGFDKETGKAIYEDEKLDL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
EPLPYIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGLHVILATQRPSVDVITGTIKA
CCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEE
NFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEKVV
CCCCEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHH
KHLKTQGQPEYLEAVTAEEPAEGEDGAVFDATGMGGDGGGDLFQQAVAIVKRDRKASTSY
HHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
IQRRLQIGYNRAASLIERMELEGIVGQPNHAGKREILVAEEDSDF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SMPAIERVIPLVGHLPTSLRDALARRLRELAGFGLISIAVMAAAALATWSVQDPSLSHA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHH
TSRKIHNLIGYPGAIGADLAMQILGLGAIGLLLPVATWGWRMINHRPFDRRALRFGAWIL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
CTILAAGFASSFPHDSAWPLPTGLGGVVGDALVRAPSLIFGPGLIFRIILSIVLGGAMVA
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHH
CFVMASGYGSREPDPVEAIADDVPLDEDEDRDEGSVSLGWMAHAVLSARARLWRLMKLGY
HHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
RGLVSSGASAGRSAAAFERQEPKLGSGRTSPPIVPRDERDDDEPLDLESADAIDDEEEDE
HHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVARAPRKKAAPKPTAKKPGKFELPSVNVLTAPKASDRQPLNKAELEANSRALEGVLQDF
HHHHCCCCCCCCCCCCCCCCCEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GVRGEIVKANPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSALSARVAVVPGRNAIGI
CCCCEEEECCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHEEEEECCCCEEEE
ELPNAHREKVYLRELLSVKDGNETVHKLPLCLGKNIGGDSIIIDLARTPHMLIAGTTGSG
ECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCC
KSVAINTMILSLVYRLRPDQCRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWA
CEEHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHCCCHHHHCCCCCCCHHHHHHHHHH
VREMEERYKRMAKLGVRNIDGYNTRLSEAKARGEELTRTVHTGFDKETGKAIYEDEKLDL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
EPLPYIVIIVDEMADLMMVAGKDIEGAVQRLAQMARAAGLHVILATQRPSVDVITGTIKA
CCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEE
NFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEKVV
CCCCEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHH
KHLKTQGQPEYLEAVTAEEPAEGEDGAVFDATGMGGDGGGDLFQQAVAIVKRDRKASTSY
HHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
IQRRLQIGYNRAASLIERMELEGIVGQPNHAGKREILVAEEDSDF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]