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The map label for this gene is cycZ [H]

Identifier: 86747492

GI number: 86747492

Start: 407589

End: 408323

Strand: Reverse

Name: cycZ [H]

Synonym: RPB_0366

Alternate gene names: 86747492

Gene position: 408323-407589 (Counterclockwise)

Preceding gene: 86747493

Following gene: 86747491

Centisome position: 7.66

GC content: 69.12

Gene sequence:

>735_bases
ATGACGCTGACCGAACTCGCCAACCCGACCCGGTTCCTGACGCTGGCTGGCCGCCTGCTGCCGTGGCTGGCGGGTGCCAC
CGCGCTGTTGCTGACCGTCGGGCTGGTGCAGTCGATGCTGGCGCCGGACGACTACCAGCAGGGCGCCACCGTCAAGATCA
TGTTCGTGCATGTGCCGAACGCCTGGCTGTCGATGTTCGTCTGGGGGGTGATGAGCGTCGCGGCGCTCGGTACACTGGTG
TGGCGGCATCCGCTCGCCGACGTCGCCGCCAAGACCGCCGCCCCGATCGGCGCCGCCTTCACCTTCCTGGCGCTGCTCAC
CGGCTCGCTGTGGGGCCGGCCGATGTGGGGCACCTATTGGGAATGGGACGCCCGGCTGACCTCGATGCTGATCCTGTTCC
TGATGTATCTCGGCCTGATCGCGCTGTGGCGCGCGGTCGAGGACCCGTCGCGGGCGGCGCGCGCCGCCGCGGTGCTGACG
CTGGTCGGCGCGATCAATCTGCCGATCATCAAATTCTCGGTCGATTGGTGGAATACGCTGCACCAGCCGGCCTCGGTGGT
GCGGATGGGCGGGCCGGCGCTGGACCAGTCGTTCCTGATTCCGCTACTGGTGATGGCGCTCGGCTTCTCGCTGCTGTTCC
TGACCCTGCACGTCGCCGCGATGCGCAACGAGATCCTGCGCCGCCGGGTGCGCACGCTGCAGATGCTGCAGGCCAGCCGC
GCCGAGGCGGCGTGA

Upstream 100 bases:

>100_bases
CCAGGCCGGGACCTCGCCGCCCGATCAACTCCCGCTGAGAACGCGGCCTCCGGAGAACGCCGCATTGCCTGCACCCGTCC
ATCCCATTATCAGGGATGCC

Downstream 100 bases:

>100_bases
TGTTCGGTCGCTATGCGGAGTTCATCGTCTCGTCCTACGCCGCGGTCGCGATCGTGGTCGTGCTGCTGATCGTCTGGGTG
GTGCTCGATTATCGCCGCCA

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTLTELANPTRFLTLAGRLLPWLAGATALLLTVGLVQSMLAPDDYQQGATVKIMFVHVPNAWLSMFVWGVMSVAALGTLV
WRHPLADVAAKTAAPIGAAFTFLALLTGSLWGRPMWGTYWEWDARLTSMLILFLMYLGLIALWRAVEDPSRAARAAAVLT
LVGAINLPIIKFSVDWWNTLHQPASVVRMGGPALDQSFLIPLLVMALGFSLLFLTLHVAAMRNEILRRRVRTLQMLQASR
AEAA

Sequences:

>Translated_244_residues
MTLTELANPTRFLTLAGRLLPWLAGATALLLTVGLVQSMLAPDDYQQGATVKIMFVHVPNAWLSMFVWGVMSVAALGTLV
WRHPLADVAAKTAAPIGAAFTFLALLTGSLWGRPMWGTYWEWDARLTSMLILFLMYLGLIALWRAVEDPSRAARAAAVLT
LVGAINLPIIKFSVDWWNTLHQPASVVRMGGPALDQSFLIPLLVMALGFSLLFLTLHVAAMRNEILRRRVRTLQMLQASR
AEAA
>Mature_243_residues
TLTELANPTRFLTLAGRLLPWLAGATALLLTVGLVQSMLAPDDYQQGATVKIMFVHVPNAWLSMFVWGVMSVAALGTLVW
RHPLADVAAKTAAPIGAAFTFLALLTGSLWGRPMWGTYWEWDARLTSMLILFLMYLGLIALWRAVEDPSRAARAAAVLTL
VGAINLPIIKFSVDWWNTLHQPASVVRMGGPALDQSFLIPLLVMALGFSLLFLTLHVAAMRNEILRRRVRTLQMLQASRA
EAA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=232, Percent_Identity=49.1379310344828, Blast_Score=210, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26821; Mature: 26690

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTELANPTRFLTLAGRLLPWLAGATALLLTVGLVQSMLAPDDYQQGATVKIMFVHVPN
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCH
AWLSMFVWGVMSVAALGTLVWRHPLADVAAKTAAPIGAAFTFLALLTGSLWGRPMWGTYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCH
EWDARLTSMLILFLMYLGLIALWRAVEDPSRAARAAAVLTLVGAINLPIIKFSVDWWNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
HQPASVVRMGGPALDQSFLIPLLVMALGFSLLFLTLHVAAMRNEILRRRVRTLQMLQASR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAA
CCCC
>Mature Secondary Structure 
TLTELANPTRFLTLAGRLLPWLAGATALLLTVGLVQSMLAPDDYQQGATVKIMFVHVPN
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCH
AWLSMFVWGVMSVAALGTLVWRHPLADVAAKTAAPIGAAFTFLALLTGSLWGRPMWGTYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCH
EWDARLTSMLILFLMYLGLIALWRAVEDPSRAARAAAVLTLVGAINLPIIKFSVDWWNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
HQPASVVRMGGPALDQSFLIPLLVMALGFSLLFLTLHVAAMRNEILRRRVRTLQMLQASR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]