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The map label for this gene is xerC [H]

Identifier: 86747397

GI number: 86747397

Start: 306126

End: 307181

Strand: Direct

Name: xerC [H]

Synonym: RPB_0271

Alternate gene names: 86747397

Gene position: 306126-307181 (Clockwise)

Preceding gene: 86747395

Following gene: 86747398

Centisome position: 5.74

GC content: 69.51

Gene sequence:

>1056_bases
ATGCCTGGCGCTTCTGGATTGCTTCGCTTTGCTCGCAATGACGGAGAGGATCTCGTTTCAGTCGGCATCCGGCATAAGCA
CCACATGGCCAAATCACAGCCCATGCCCCCTCCGATCGACCTGCCTTGCGCCGCCGCCGATCTCAACGCGGAATTCACCC
GCTGGCTGTCGCATCTGCGCGCCGAGCGCCGGCTGTCCGGCAAGACGCTGGAGGCCTATGCGCGCGACCTGCGCCAGTTT
CTGTTTTTTCTCGCCGGCCATTGGGGCGGCGAGGTGACGCTCGGCCGCTTCGCGCGACTGGAAACAACCGACGTGCGCGC
CTTCATGGCGGCGCGGCGCGGCGATGCGATCGCCGGCCGCTCGCTGATGCGGGCGCTGGCCGGGCTGCGCTCGTTCGGCC
GCTTCCTCGAACGCGAGGGCAAGGGCAGCGTCGGCGCGCTGTCGGCGGTGCGGGCGCCGAAGATCAAGAAGAGCCTGCCG
AAGCCGATCCAGATCGCCGCCGCCAAGCGGCTGGCGGACGCCGACGAGCGCGCCGGCGAGGATCGCGAGACCTGGGTGCT
GGTTCGCGACGCCGCCGTGATGGCGTTGCTGTACGGCTCCGGCCTGCGCATCTCCGAAGCGCTCGGGCTGAAGCGTCGCG
ACGTACCGGCGCCGGGCAAGGGCGACACCCTGATCGTACTCGGCAAGGGCAACAAGACCCGGATGGTGCCGGTGCTCGAC
GCCGTGCTGGCGCAGATCGCCGACTACGCGAAAGCCTGCCCGCATCCGCTGCCGCCGGACGGGCCGATGTTCGTCGGCGC
GCGCGGCGGGCCGCTCAGCCCGCGAATCATCCAGCTGGCGATGGAGCGGCTGCGCGGCGCGCTTGGACTGCCGGATTCGG
CCACCCCGCACGCGCTGCGGCACTCTTTCGCGACGCATCTTCTGAGCCGCGGCGGCGATTTGCGCGCGATCCAGGAATTG
CTCGGCCACGCCTCGCTGTCGACCACGCAGATTTATACCGGCATCGACACCGAGCGGCTGCTGGAAGTCTACGCCAGCGC
CCATCCGCGCGCGTGA

Upstream 100 bases:

>100_bases
AAAGCGGCCTTTCATCAATGGGAAAGGAAATCGGCTATGATCGGGCCACAACCTCCGCGTCATTGCGAGGAGCGAAGCGA
CGAAGCAATCCAGGAGCCCC

Downstream 100 bases:

>100_bases
CGACGCCGAAGTTGTTAGCACGCGATCACCGGGCTTGACCCGCAACGCCTTCCAACTGACAAGTTCCTGATCTGATGATC
AGTTGCCCGGCCGGTGCCGG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPGASGLLRFARNDGEDLVSVGIRHKHHMAKSQPMPPPIDLPCAAADLNAEFTRWLSHLRAERRLSGKTLEAYARDLRQF
LFFLAGHWGGEVTLGRFARLETTDVRAFMAARRGDAIAGRSLMRALAGLRSFGRFLEREGKGSVGALSAVRAPKIKKSLP
KPIQIAAAKRLADADERAGEDRETWVLVRDAAVMALLYGSGLRISEALGLKRRDVPAPGKGDTLIVLGKGNKTRMVPVLD
AVLAQIADYAKACPHPLPPDGPMFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQEL
LGHASLSTTQIYTGIDTERLLEVYASAHPRA

Sequences:

>Translated_351_residues
MPGASGLLRFARNDGEDLVSVGIRHKHHMAKSQPMPPPIDLPCAAADLNAEFTRWLSHLRAERRLSGKTLEAYARDLRQF
LFFLAGHWGGEVTLGRFARLETTDVRAFMAARRGDAIAGRSLMRALAGLRSFGRFLEREGKGSVGALSAVRAPKIKKSLP
KPIQIAAAKRLADADERAGEDRETWVLVRDAAVMALLYGSGLRISEALGLKRRDVPAPGKGDTLIVLGKGNKTRMVPVLD
AVLAQIADYAKACPHPLPPDGPMFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQEL
LGHASLSTTQIYTGIDTERLLEVYASAHPRA
>Mature_350_residues
PGASGLLRFARNDGEDLVSVGIRHKHHMAKSQPMPPPIDLPCAAADLNAEFTRWLSHLRAERRLSGKTLEAYARDLRQFL
FFLAGHWGGEVTLGRFARLETTDVRAFMAARRGDAIAGRSLMRALAGLRSFGRFLEREGKGSVGALSAVRAPKIKKSLPK
PIQIAAAKRLADADERAGEDRETWVLVRDAAVMALLYGSGLRISEALGLKRRDVPAPGKGDTLIVLGKGNKTRMVPVLDA
VLAQIADYAKACPHPLPPDGPMFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELL
GHASLSTTQIYTGIDTERLLEVYASAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=306, Percent_Identity=36.2745098039216, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789261, Length=310, Percent_Identity=33.2258064516129, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37978; Mature: 37846

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGASGLLRFARNDGEDLVSVGIRHKHHMAKSQPMPPPIDLPCAAADLNAEFTRWLSHLR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHH
AERRLSGKTLEAYARDLRQFLFFLAGHWGGEVTLGRFARLETTDVRAFMAARRGDAIAGR
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHH
SLMRALAGLRSFGRFLEREGKGSVGALSAVRAPKIKKSLPKPIQIAAAKRLADADERAGE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHCCC
DRETWVLVRDAAVMALLYGSGLRISEALGLKRRDVPAPGKGDTLIVLGKGNKTRMVPVLD
CCCEEEEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AVLAQIADYAKACPHPLPPDGPMFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALR
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
HSFATHLLSRGGDLRAIQELLGHASLSTTQIYTGIDTERLLEVYASAHPRA
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PGASGLLRFARNDGEDLVSVGIRHKHHMAKSQPMPPPIDLPCAAADLNAEFTRWLSHLR
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHH
AERRLSGKTLEAYARDLRQFLFFLAGHWGGEVTLGRFARLETTDVRAFMAARRGDAIAGR
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHH
SLMRALAGLRSFGRFLEREGKGSVGALSAVRAPKIKKSLPKPIQIAAAKRLADADERAGE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHCCC
DRETWVLVRDAAVMALLYGSGLRISEALGLKRRDVPAPGKGDTLIVLGKGNKTRMVPVLD
CCCEEEEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
AVLAQIADYAKACPHPLPPDGPMFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALR
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
HSFATHLLSRGGDLRAIQELLGHASLSTTQIYTGIDTERLLEVYASAHPRA
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHEEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]