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The map label for this gene is ubiG

Identifier: 86747206

GI number: 86747206

Start: 81916

End: 82677

Strand: Direct

Name: ubiG

Synonym: RPB_0079

Alternate gene names: 86747206

Gene position: 81916-82677 (Clockwise)

Preceding gene: 86747205

Following gene: 86747208

Centisome position: 1.54

GC content: 64.04

Gene sequence:

>762_bases
ATGGCACTGCAATCCGAATCTCCCGGTCCCGTGTCGCCTTCGGTCGATCCGGCCGAAATCGCGAAATTCTCCAAGCTGTC
GGCGCAATGGTGGGATCCGACCGGCAAGATGGCGCCGCTGCACCGGATCAACCCGCTGCGGATCAGCTTCATCCGCGACG
CCGCCTGCCGCAAATTCGAGCGCAACGCCAAGAGCCTGAGCTGCCTGTCGGGGCTGCGGATGCTCGATATCGGCTGCGGC
GCCGGCCTGTTGTGCGAGCCGTTCACAAGGCTCGGCGCCCAGGTGATCGGGATCGATCCGTCGGCGACCAACATCGCCGC
GGCGAAGATCCATGCCGACAAATCGCATCTGCCGATCGACTATCGCTGCACCACGGTCGAGGAGATCGACCCGCGCGAGC
GCTTCGACATCGTGCTGGCGATGGAAGTGATCGAGCACGTCACCGATGTCGGCGCCTTCCTCGGGCGCTGCGCGGCGCTG
ATGAAGCCCAACGGCATCATGGTGGTGGCGACGCTCAATCGGAACTGGAAGAGCTTCGCGCTGGCAATCGTCGGCGCCGA
ATATGTGATGCGCTGGCTGCCGCGCGGCACCCATCAATGGGACAAATTCGTCACGCCCGCCGAACTCGAGCAGCATCTGC
ACGGCTTCGGGATGATTGTGACCGAACAGTCCGGCCTGGTGTTCAATCCGCTCGCCGACCGCTGGAAGCTGTCCGCCGAC
ATGGACGTGAACTACATGGTGGTAGCGGAGACGGCGCCGTAG

Upstream 100 bases:

>100_bases
CGTTCTGGGCGTCGGCGAGGGGCGGGAAACCATCCGGACCGTCGCCGCCCCGCTGGCGTTCCGAAGTTCAATAACCGCGC
GATAGGAGCACGGCGCATCC

Downstream 100 bases:

>100_bases
CCCATCGACGCCGTCGTGTGGCCCGCCGAAGGCCGGGCGCCGCCGAAGGCCGGGACAAAGGCACAACTGATTTGATCCGT
CATTGCGAGCGAAGCGAAGC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MALQSESPGPVSPSVDPAEIAKFSKLSAQWWDPTGKMAPLHRINPLRISFIRDAACRKFERNAKSLSCLSGLRMLDIGCG
AGLLCEPFTRLGAQVIGIDPSATNIAAAKIHADKSHLPIDYRCTTVEEIDPRERFDIVLAMEVIEHVTDVGAFLGRCAAL
MKPNGIMVVATLNRNWKSFALAIVGAEYVMRWLPRGTHQWDKFVTPAELEQHLHGFGMIVTEQSGLVFNPLADRWKLSAD
MDVNYMVVAETAP

Sequences:

>Translated_253_residues
MALQSESPGPVSPSVDPAEIAKFSKLSAQWWDPTGKMAPLHRINPLRISFIRDAACRKFERNAKSLSCLSGLRMLDIGCG
AGLLCEPFTRLGAQVIGIDPSATNIAAAKIHADKSHLPIDYRCTTVEEIDPRERFDIVLAMEVIEHVTDVGAFLGRCAAL
MKPNGIMVVATLNRNWKSFALAIVGAEYVMRWLPRGTHQWDKFVTPAELEQHLHGFGMIVTEQSGLVFNPLADRWKLSAD
MDVNYMVVAETAP
>Mature_252_residues
ALQSESPGPVSPSVDPAEIAKFSKLSAQWWDPTGKMAPLHRINPLRISFIRDAACRKFERNAKSLSCLSGLRMLDIGCGA
GLLCEPFTRLGAQVIGIDPSATNIAAAKIHADKSHLPIDYRCTTVEEIDPRERFDIVLAMEVIEHVTDVGAFLGRCAALM
KPNGIMVVATLNRNWKSFALAIVGAEYVMRWLPRGTHQWDKFVTPAELEQHLHGFGMIVTEQSGLVFNPLADRWKLSADM
DVNYMVVAETAP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=42.3868312757202, Blast_Score=197, Evalue=8e-51,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=41.6666666666667, Blast_Score=194, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI115533050, Length=246, Percent_Identity=35.7723577235772, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6324476, Length=246, Percent_Identity=27.6422764227642, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281365311, Length=242, Percent_Identity=30.1652892561983, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24585589, Length=221, Percent_Identity=33.0316742081448, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_RHOP2 (Q2J419)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_483702.1
- ProteinModelPortal:   Q2J419
- SMR:   Q2J419
- STRING:   Q2J419
- GeneID:   3908721
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0079
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   KFITPDE
- ProtClustDB:   PRK05134
- BioCyc:   RPAL316058:RPB_0079-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27914; Mature: 27782

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQSESPGPVSPSVDPAEIAKFSKLSAQWWDPTGKMAPLHRINPLRISFIRDAACRKFE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
RNAKSLSCLSGLRMLDIGCGAGLLCEPFTRLGAQVIGIDPSATNIAAAKIHADKSHLPID
HCHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCEE
YRCTTVEEIDPRERFDIVLAMEVIEHVTDVGAFLGRCAALMKPNGIMVVATLNRNWKSFA
EEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
LAIVGAEYVMRWLPRGTHQWDKFVTPAELEQHLHGFGMIVTEQSGLVFNPLADRWKLSAD
HHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCEEEEEECCCEEECCCCCCEEECCC
MDVNYMVVAETAP
CCCEEEEEEECCC
>Mature Secondary Structure 
ALQSESPGPVSPSVDPAEIAKFSKLSAQWWDPTGKMAPLHRINPLRISFIRDAACRKFE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
RNAKSLSCLSGLRMLDIGCGAGLLCEPFTRLGAQVIGIDPSATNIAAAKIHADKSHLPID
HCHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCEE
YRCTTVEEIDPRERFDIVLAMEVIEHVTDVGAFLGRCAALMKPNGIMVVATLNRNWKSFA
EEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
LAIVGAEYVMRWLPRGTHQWDKFVTPAELEQHLHGFGMIVTEQSGLVFNPLADRWKLSAD
HHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCEEEEEECCCEEECCCCCCEEECCC
MDVNYMVVAETAP
CCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA