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The map label for this gene is frr

Identifier: 86610317

GI number: 86610317

Start: 2995100

End: 2995648

Strand: Direct

Name: frr

Synonym: CYB_2897

Alternate gene names: 86610317

Gene position: 2995100-2995648 (Clockwise)

Preceding gene: 86610315

Following gene: 86610318

Centisome position: 98.31

GC content: 57.92

Gene sequence:

>549_bases
GTGGAGCTAGCTGAGATTGAGGAGTTGATGAACAAAGCTGTGCAAGCCACACAGCGCTCCTTTAATACGGTGCGCACCGG
GCGGGCCAATTCCAGCCTGCTGGATCGCATTCAGGTGGAGTACTACGGCGTGCCCACTCCCCTCAAGGCCCTGGCCAGCC
TCACCACGCCAGACTCCAGCACTCTCTTGATCCAGCCTTTTGATCCCTCGACCTTGGCGGCCATTGAGCGGGCCATTGTT
GCCTCTGACCTAGGTCTAACCCCCAGCAACGACGGCAAGGTGGTGCGGCTCACCATTCCCCCCCTGACGGAAGAGCGCCG
CAAAGAGCTGAGCAAACAGGTGGCCAAGCTAGCCGAAGAGGGGCGAGTCTCAATCCGCAACATCCGGCGGGATGGCATCG
ACTCGGTGCGCAAGCGGGAGAAAAACGGCGAGCTGTCTGAAGATGAGTCCAAAAGCTTGCAGGATGACATCCAGAAGCTG
ACCGACCGCTATATCAAAAAGATCGATGAGCTGCTGGCAGAAAAAGAAAAGGAGCTGACGACGCTGTAA

Upstream 100 bases:

>100_bases
GACAAGGCGGTAGAATTGAGGTCAGGCTCACCGTAGAGGGGCCAGGTTGGCTGCCCAAGCCTGACTGTCTGGAAACTGTT
TTGAAAGCGAGGAAAACCCC

Downstream 100 bases:

>100_bases
AAGCTCCTTGTGGACATAACTCCCCACGCTACTGGCCTGCTTCTGCATAGCCGTAGGACGGGGTTATGACCCAATTTTTT
GATAAAAACCCGGACACCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MELAEIEELMNKAVQATQRSFNTVRTGRANSSLLDRIQVEYYGVPTPLKALASLTTPDSSTLLIQPFDPSTLAAIERAIV
ASDLGLTPSNDGKVVRLTIPPLTEERRKELSKQVAKLAEEGRVSIRNIRRDGIDSVRKREKNGELSEDESKSLQDDIQKL
TDRYIKKIDELLAEKEKELTTL

Sequences:

>Translated_182_residues
MELAEIEELMNKAVQATQRSFNTVRTGRANSSLLDRIQVEYYGVPTPLKALASLTTPDSSTLLIQPFDPSTLAAIERAIV
ASDLGLTPSNDGKVVRLTIPPLTEERRKELSKQVAKLAEEGRVSIRNIRRDGIDSVRKREKNGELSEDESKSLQDDIQKL
TDRYIKKIDELLAEKEKELTTL
>Mature_182_residues
MELAEIEELMNKAVQATQRSFNTVRTGRANSSLLDRIQVEYYGVPTPLKALASLTTPDSSTLLIQPFDPSTLAAIERAIV
ASDLGLTPSNDGKVVRLTIPPLTEERRKELSKQVAKLAEEGRVSIRNIRRDGIDSVRKREKNGELSEDESKSLQDDIQKL
TDRYIKKIDELLAEKEKELTTL

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=173, Percent_Identity=54.3352601156069, Blast_Score=181, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24661488, Length=171, Percent_Identity=30.4093567251462, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SYNJB (Q2JHW2)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_479079.1
- ProteinModelPortal:   Q2JHW2
- SMR:   Q2JHW2
- STRING:   Q2JHW2
- GeneID:   3900561
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_2897
- TIGR:   CYB_2897
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   CEATTIR
- PhylomeDB:   Q2JHW2
- ProtClustDB:   PRK00083
- BioCyc:   SSP321332:CYB_2897-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20391; Mature: 20391

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAEIEELMNKAVQATQRSFNTVRTGRANSSLLDRIQVEYYGVPTPLKALASLTTPDSS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
TLLIQPFDPSTLAAIERAIVASDLGLTPSNDGKVVRLTIPPLTEERRKELSKQVAKLAEE
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
GRVSIRNIRRDGIDSVRKREKNGELSEDESKSLQDDIQKLTDRYIKKIDELLAEKEKELT
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TL
CC
>Mature Secondary Structure
MELAEIEELMNKAVQATQRSFNTVRTGRANSSLLDRIQVEYYGVPTPLKALASLTTPDSS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
TLLIQPFDPSTLAAIERAIVASDLGLTPSNDGKVVRLTIPPLTEERRKELSKQVAKLAEE
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
GRVSIRNIRRDGIDSVRKREKNGELSEDESKSLQDDIQKLTDRYIKKIDELLAEKEKELT
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA