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The map label for this gene is macB [H]

Identifier: 86610311

GI number: 86610311

Start: 2989447

End: 2990658

Strand: Direct

Name: macB [H]

Synonym: CYB_2892

Alternate gene names: 86610311

Gene position: 2989447-2990658 (Clockwise)

Preceding gene: 86610310

Following gene: 86610314

Centisome position: 98.12

GC content: 62.46

Gene sequence:

>1212_bases
ATGAGCCTGGCAACGGCGGCCAAAATGGCCTGGCAAATGGTGCGACGACATCGCCTGCGCACCGGGCTGAGCATGCTCGG
GATCCTCATCGGCAATGCGGCGGTGGTGGCCATTGCCGGATTTGGCTATGCTGCCCAAGAGATGGCGGTGGATCAATTTC
GCTCTCTGGGCACCAACTTGCTGATCGTCTTTTCGGCCAACTTGGGCCTGGTCGATGCCGGCAACATCCGCCCCCTCACT
TTGGAGGATGTGCGAGCCATTGCTGCGGAAGTGCCTGCCGTGTCAGCAGCCGTCCCCAGCCTGGGCACCAATGTGCGCGC
GGTGCGAGGTGGAGTGGATCGCCGCTACGAGGCCACCGGCACTTGGCCGGAGTATTTGTCGGTGTTGAACTTAGAGATCG
AGGCAGGCCGCTTCCTCTTGCCCTCGGATATCGAGGAACAGCGCCCGGTGGTGGTGCTGGGCAGCGATGCCGCCAGCCAG
TTGTTCGGCCTGGATCCCGCCGCTGCCATTGGGGAGACCGTCCTGCTGAACAACTTGCCCTTCGAGGTAATCGGCACTTT
GCGCTCGAAGCCGACGGTGTTTGGCAACAGCGATGCCGGAGTGTTTCTGCCGGTGGATGTGGTGGCCAATCAGTTGGTCG
GGCGGCGTTCCCCCTACGGCACAGAGCTGACGGCGATTTTCGTCTCGGCCCGCTCTGAAGCCGATCTGCCTGCTGCCGAG
TTCCAAATCCGCAACCTGCTGCGCCAGCGGCACCAATTGGTGGGAGAAGATGACTTCATCATCCGCAACCAGAAAGTGCT
CCTGGATGGGTCGGCCAGGATTTTGAGCCTGTTGCGGGTGCTGCTGACGGGCACGGCGGCCCTCTCCCTGCTGGTGGGAG
GGGTGGGGATCATGAATGTGATGCTTATCTCAGTTGCGGAACGCACCCATGAAATCGGGCTGCGCAAGGCGATTGGGGCG
GATAGCCGGCAGATTTTGCAGCAGTTTGCCGCCGAAGCGATTTTCATTGCCGTGACCGGGGGGGTGCTCGGGATCCTCCT
CAGCAGCGGCCTGCTGGTGGCGGTGCAGGTGTTCACCCCCTTGGCCACCCAAGTCGATGGGGTGGCAGTGGGAGTGGCGT
TCTCCCTGTCCACTGGGATTGGGCTAGTCTTTGGCATTTTCCCGGCCCGCAAAGCGGCGCAACTGGATCCCATTGAGGCC
CTGCGGGCCTAG

Upstream 100 bases:

>100_bases
CCCAGATCCTCTCCGGTCTGCAGGCAGGGGATCGGGTCTTTACTGCCCTGCCTCCTGGGGTGAACCTAGAGACTTTGATT
AAAAGAGCGGAGCAACAGCC

Downstream 100 bases:

>100_bases
AGATCGTATCCAAACAGGCGGGGATCCGCCGGCTGCCAATTGAGATCCGCCAGGCCATATTCTGCCCAGCGGCGATCCAC
CAAGCGGGCCACCTCCGGAT

Product: macrolide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSLATAAKMAWQMVRRHRLRTGLSMLGILIGNAAVVAIAGFGYAAQEMAVDQFRSLGTNLLIVFSANLGLVDAGNIRPLT
LEDVRAIAAEVPAVSAAVPSLGTNVRAVRGGVDRRYEATGTWPEYLSVLNLEIEAGRFLLPSDIEEQRPVVVLGSDAASQ
LFGLDPAAAIGETVLLNNLPFEVIGTLRSKPTVFGNSDAGVFLPVDVVANQLVGRRSPYGTELTAIFVSARSEADLPAAE
FQIRNLLRQRHQLVGEDDFIIRNQKVLLDGSARILSLLRVLLTGTAALSLLVGGVGIMNVMLISVAERTHEIGLRKAIGA
DSRQILQQFAAEAIFIAVTGGVLGILLSSGLLVAVQVFTPLATQVDGVAVGVAFSLSTGIGLVFGIFPARKAAQLDPIEA
LRA

Sequences:

>Translated_403_residues
MSLATAAKMAWQMVRRHRLRTGLSMLGILIGNAAVVAIAGFGYAAQEMAVDQFRSLGTNLLIVFSANLGLVDAGNIRPLT
LEDVRAIAAEVPAVSAAVPSLGTNVRAVRGGVDRRYEATGTWPEYLSVLNLEIEAGRFLLPSDIEEQRPVVVLGSDAASQ
LFGLDPAAAIGETVLLNNLPFEVIGTLRSKPTVFGNSDAGVFLPVDVVANQLVGRRSPYGTELTAIFVSARSEADLPAAE
FQIRNLLRQRHQLVGEDDFIIRNQKVLLDGSARILSLLRVLLTGTAALSLLVGGVGIMNVMLISVAERTHEIGLRKAIGA
DSRQILQQFAAEAIFIAVTGGVLGILLSSGLLVAVQVFTPLATQVDGVAVGVAFSLSTGIGLVFGIFPARKAAQLDPIEA
LRA
>Mature_402_residues
SLATAAKMAWQMVRRHRLRTGLSMLGILIGNAAVVAIAGFGYAAQEMAVDQFRSLGTNLLIVFSANLGLVDAGNIRPLTL
EDVRAIAAEVPAVSAAVPSLGTNVRAVRGGVDRRYEATGTWPEYLSVLNLEIEAGRFLLPSDIEEQRPVVVLGSDAASQL
FGLDPAAAIGETVLLNNLPFEVIGTLRSKPTVFGNSDAGVFLPVDVVANQLVGRRSPYGTELTAIFVSARSEADLPAAEF
QIRNLLRQRHQLVGEDDFIIRNQKVLLDGSARILSLLRVLLTGTAALSLLVGGVGIMNVMLISVAERTHEIGLRKAIGAD
SRQILQQFAAEAIFIAVTGGVLGILLSSGLLVAVQVFTPLATQVDGVAVGVAFSLSTGIGLVFGIFPARKAAQLDPIEAL
RA

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=399, Percent_Identity=36.8421052631579, Blast_Score=218, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42549; Mature: 42418

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00475 RIBOSOMAL_L15

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLATAAKMAWQMVRRHRLRTGLSMLGILIGNAAVVAIAGFGYAAQEMAVDQFRSLGTNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCE
LIVFSANLGLVDAGNIRPLTLEDVRAIAAEVPAVSAAVPSLGTNVRAVRGGVDRRYEATG
EEEEECCCCEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCEECCC
TWPEYLSVLNLEIEAGRFLLPSDIEEQRPVVVLGSDAASQLFGLDPAAAIGETVLLNNLP
CCHHHHHHEEEEECCCCEECCCCCCCCCCEEEECCCHHHHHHCCCHHHHHCCCCEECCCC
FEVIGTLRSKPTVFGNSDAGVFLPVDVVANQLVGRRSPYGTELTAIFVSARSEADLPAAE
HHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHH
FQIRNLLRQRHQLVGEDDFIIRNQKVLLDGSARILSLLRVLLTGTAALSLLVGGVGIMNV
HHHHHHHHHHHHHCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLISVAERTHEIGLRKAIGADSRQILQQFAAEAIFIAVTGGVLGILLSSGLLVAVQVFTP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHCCHHEEHHHHHH
LATQVDGVAVGVAFSLSTGIGLVFGIFPARKAAQLDPIEALRA
HHHHCCCEEEEEEEEHHCCHHHHHHHCCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
SLATAAKMAWQMVRRHRLRTGLSMLGILIGNAAVVAIAGFGYAAQEMAVDQFRSLGTNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCE
LIVFSANLGLVDAGNIRPLTLEDVRAIAAEVPAVSAAVPSLGTNVRAVRGGVDRRYEATG
EEEEECCCCEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCEECCC
TWPEYLSVLNLEIEAGRFLLPSDIEEQRPVVVLGSDAASQLFGLDPAAAIGETVLLNNLP
CCHHHHHHEEEEECCCCEECCCCCCCCCCEEEECCCHHHHHHCCCHHHHHCCCCEECCCC
FEVIGTLRSKPTVFGNSDAGVFLPVDVVANQLVGRRSPYGTELTAIFVSARSEADLPAAE
HHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHH
FQIRNLLRQRHQLVGEDDFIIRNQKVLLDGSARILSLLRVLLTGTAALSLLVGGVGIMNV
HHHHHHHHHHHHHCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLISVAERTHEIGLRKAIGADSRQILQQFAAEAIFIAVTGGVLGILLSSGLLVAVQVFTP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHCCHHEEHHHHHH
LATQVDGVAVGVAFSLSTGIGLVFGIFPARKAAQLDPIEALRA
HHHHCCCEEEEEEEEHHCCHHHHHHHCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA