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The map label for this gene is sbcD [H]

Identifier: 86610201

GI number: 86610201

Start: 2869975

End: 2871279

Strand: Direct

Name: sbcD [H]

Synonym: CYB_2775

Alternate gene names: 86610201

Gene position: 2869975-2871279 (Clockwise)

Preceding gene: 86610200

Following gene: 86610202

Centisome position: 94.2

GC content: 59.16

Gene sequence:

>1305_bases
ATGGTAAGGTTGCTACATCTTTCCGACATTCATCTGGGCAGTGGTCTTGCCTACGGCCACATTAACCCAGCTACCGGCCT
GAATACCCGTTTGGAAGATTTTGTAGCTTCTTTGCGCTTGTGCATTGACCATGCTCTCAACCAAGCGGTGGATCTGGTGT
TGTTTGGGGGCGATGCTTTCCCCGATGCGACACCCCCCCCTCTCCATCAAGAGCTTTTTGCCCAACAGTTTCGCCGCCTG
GCCGATGCAGGGATCCCAACCGTCCTGTTGGTGGGCAACCACGATCAGTACGGGCAGGGACAGGGAGGCAACAGCCTGGC
TATCTACCGCGCTTTGGGGGTCTCAGGCTTTATTGTGGGGGACAGACTGGAAACTCATCGGATCGAAACTCGCGGTGGCC
CGGTGCAGGTGACCACTTTACCTTGGCTGAGTCGCTCTGCTCTACTCGCCCAACAGGAAAGCTTGGCGCTTGAAGGGGAA
ATCCTCGCGCATCAGCTCCTGCAGCGCCTCCGCCTAGCCCTAGAAGGGGAGATCCGCACCCTGCAGCCAGGGATCCCGGC
GATTTTGTTGGCTCACGTCATGGTGGAGACAGCCCGCTACGGAGCAGAACGCCATCTTTCGGTGGGCAGAGGATTTACGG
TGCCCCTTTCGCTGCTGGCTCGGCCTGCCTATCAATATGTTGCCTTGGGGCATGTACACCGTCACCAGGTGCTGTGTCGG
GATCCCTTGATGCTCTATCCCGGCAGCATTGAGCGGGTGGATTTTGGCGAAGAAAAAGAGGAAAAAGGCTGTGTGCTGGT
GGAAGTCACCCCTACGGGGGCCAGCTATGAATTTTTGCCCCTGCCAACCCGTACCTTTCACACCATTCGCCTGGATCTGA
GCGCAGATCCACCCCAGCAGGCGCAGTCCAAGCTGCTGGCCGCCATCGCCAAGGCCCCCGTGGCCGGCTCCATCCTGCGG
TTGATCTACCGCATACGGCCCGACCAGCTAGAGTGCATTGATGAGCGGGCTCTGCACAACGCTCTTGCCCCTGCTTTTAG
CTACACCATCGCCCCAGAAGTGGTCAGCCCCAGCCGCATCCGTCTGCCGGGATGGGATCCCAGCCGACTTGAGCCCCTGA
CGGCTCTGGAGCAGTATTTGGCCAACCGCAGCGATCTGGCCCCCTTGCACAACGATTTGCTGGCCGCCGCCCGTCAGTTG
TTGGAGGAATATGCGGATCCCTTGCAGGACTGGGATCCCAACTGGGAGGAGCCGGGAGCTTCAAGCCCTGCCTCAGCAGA
AGAGGAGCAGTTGCCTTTGTTTTGA

Upstream 100 bases:

>100_bases
TTGCCATTCTGGGCAACCAAAGGACTCCGTCCCGCTAACGCGAACGGCAAGGTTTATCCCAACAGATGGGAGAGCTGCAA
AGTCTCCAAGAGCGCCCAAG

Downstream 100 bases:

>100_bases
GATGCTCCCTTTGTCGCCTCAGGGTTCGTAGGGGTGGGGATGGGGGATCCCTGTACGAAGAAATCAGGACAGGAGTGCTC
GCCAAAGCTGCGGGCTCCTC

Product: nuclease SbcCD, D subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MVRLLHLSDIHLGSGLAYGHINPATGLNTRLEDFVASLRLCIDHALNQAVDLVLFGGDAFPDATPPPLHQELFAQQFRRL
ADAGIPTVLLVGNHDQYGQGQGGNSLAIYRALGVSGFIVGDRLETHRIETRGGPVQVTTLPWLSRSALLAQQESLALEGE
ILAHQLLQRLRLALEGEIRTLQPGIPAILLAHVMVETARYGAERHLSVGRGFTVPLSLLARPAYQYVALGHVHRHQVLCR
DPLMLYPGSIERVDFGEEKEEKGCVLVEVTPTGASYEFLPLPTRTFHTIRLDLSADPPQQAQSKLLAAIAKAPVAGSILR
LIYRIRPDQLECIDERALHNALAPAFSYTIAPEVVSPSRIRLPGWDPSRLEPLTALEQYLANRSDLAPLHNDLLAAARQL
LEEYADPLQDWDPNWEEPGASSPASAEEEQLPLF

Sequences:

>Translated_434_residues
MVRLLHLSDIHLGSGLAYGHINPATGLNTRLEDFVASLRLCIDHALNQAVDLVLFGGDAFPDATPPPLHQELFAQQFRRL
ADAGIPTVLLVGNHDQYGQGQGGNSLAIYRALGVSGFIVGDRLETHRIETRGGPVQVTTLPWLSRSALLAQQESLALEGE
ILAHQLLQRLRLALEGEIRTLQPGIPAILLAHVMVETARYGAERHLSVGRGFTVPLSLLARPAYQYVALGHVHRHQVLCR
DPLMLYPGSIERVDFGEEKEEKGCVLVEVTPTGASYEFLPLPTRTFHTIRLDLSADPPQQAQSKLLAAIAKAPVAGSILR
LIYRIRPDQLECIDERALHNALAPAFSYTIAPEVVSPSRIRLPGWDPSRLEPLTALEQYLANRSDLAPLHNDLLAAARQL
LEEYADPLQDWDPNWEEPGASSPASAEEEQLPLF
>Mature_434_residues
MVRLLHLSDIHLGSGLAYGHINPATGLNTRLEDFVASLRLCIDHALNQAVDLVLFGGDAFPDATPPPLHQELFAQQFRRL
ADAGIPTVLLVGNHDQYGQGQGGNSLAIYRALGVSGFIVGDRLETHRIETRGGPVQVTTLPWLSRSALLAQQESLALEGE
ILAHQLLQRLRLALEGEIRTLQPGIPAILLAHVMVETARYGAERHLSVGRGFTVPLSLLARPAYQYVALGHVHRHQVLCR
DPLMLYPGSIERVDFGEEKEEKGCVLVEVTPTGASYEFLPLPTRTFHTIRLDLSADPPQQAQSKLLAAIAKAPVAGSILR
LIYRIRPDQLECIDERALHNALAPAFSYTIAPEVVSPSRIRLPGWDPSRLEPLTALEQYLANRSDLAPLHNDLLAAARQL
LEEYADPLQDWDPNWEEPGASSPASAEEEQLPLF

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 47694; Mature: 47694

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRLLHLSDIHLGSGLAYGHINPATGLNTRLEDFVASLRLCIDHALNQAVDLVLFGGDAF
CEEEEEECCEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
PDATPPPLHQELFAQQFRRLADAGIPTVLLVGNHDQYGQGQGGNSLAIYRALGVSGFIVG
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEC
DRLETHRIETRGGPVQVTTLPWLSRSALLAQQESLALEGEILAHQLLQRLRLALEGEIRT
CCHHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LQPGIPAILLAHVMVETARYGAERHLSVGRGFTVPLSLLARPAYQYVALGHVHRHQVLCR
ECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHC
DPLMLYPGSIERVDFGEEKEEKGCVLVEVTPTGASYEFLPLPTRTFHTIRLDLSADPPQQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEEECCCCCHHH
AQSKLLAAIAKAPVAGSILRLIYRIRPDQLECIDERALHNALAPAFSYTIAPEVVSPSRI
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEE
RLPGWDPSRLEPLTALEQYLANRSDLAPLHNDLLAAARQLLEEYADPLQDWDPNWEEPGA
ECCCCCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SSPASAEEEQLPLF
CCCCCCCCCCCCCC
>Mature Secondary Structure
MVRLLHLSDIHLGSGLAYGHINPATGLNTRLEDFVASLRLCIDHALNQAVDLVLFGGDAF
CEEEEEECCEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCC
PDATPPPLHQELFAQQFRRLADAGIPTVLLVGNHDQYGQGQGGNSLAIYRALGVSGFIVG
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEC
DRLETHRIETRGGPVQVTTLPWLSRSALLAQQESLALEGEILAHQLLQRLRLALEGEIRT
CCHHHHEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LQPGIPAILLAHVMVETARYGAERHLSVGRGFTVPLSLLARPAYQYVALGHVHRHQVLCR
ECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHC
DPLMLYPGSIERVDFGEEKEEKGCVLVEVTPTGASYEFLPLPTRTFHTIRLDLSADPPQQ
CCCEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEEEECCCCCHHH
AQSKLLAAIAKAPVAGSILRLIYRIRPDQLECIDERALHNALAPAFSYTIAPEVVSPSRI
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEE
RLPGWDPSRLEPLTALEQYLANRSDLAPLHNDLLAAARQLLEEYADPLQDWDPNWEEPGA
ECCCCCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SSPASAEEEQLPLF
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 10568751; 1646786; 8493111 [H]