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The map label for this gene is sigC [H]

Identifier: 86610159

GI number: 86610159

Start: 2827533

End: 2828633

Strand: Direct

Name: sigC [H]

Synonym: CYB_2734

Alternate gene names: 86610159

Gene position: 2827533-2828633 (Clockwise)

Preceding gene: 86610157

Following gene: 86610164

Centisome position: 92.81

GC content: 58.04

Gene sequence:

>1101_bases
ATGTCTAACTACGAACCTGAACTCAACGACATTTTGTTGGATGGCCCCGCCGATCTCCTCGAGGCTGCCGAAGAAGCAGA
GGTGGATCTGGCCGATGGCGAGTTTCTGGAAGAGGAGCCAACCCGCCGCTCCACTGATCTGGTGCGCCTCTATTTACAGG
AGATTGGTCGTGTTCCTCTTTTGGGGCGCGATGAAGAGGTGGCCCTGGCCCAAAAAGTCCAAGACTACATGAAGCTCTTG
GATTTGCGTCTGCGTTTGCAGAAAGAGTTGGGACGGGATCCCACTCTTGCGGAATGGGTGGCCAAGGCCAACCAGTACCC
CGAGTGGGCGCAACTGACCCCTGAAAAGCTGCAGCAGATTCAGCGGATTGGCAAGCGTGCCAAAGAACACATGATCAAGG
CCAACCTGCGCCTGGTGGTGTCGGTGGCGAAAAAGTACCAAAACCGCGGCTTGGAGCTGTTGGATCTGATCCAAGAGGGT
ACGCTGGGCCTAGAGCGGGCGGTGGAAAAGTTCGACCCAAAAAAGGGCTACCGCTTCAGCACCTACGCCTACTGGTGGAT
CCGGCAGGGCATTACCCGCGCCATTGCCACCCAAAGCCGCACCATCCGCCTGCCCGTTCACATCACCGAGAAGCTGAACA
AGATCAAAAAAGCGCAGCGCAAGCTCTCCCAGGAAAAGGGCCGCACCCCCACCATCGAAGACATCGCCTCCGAGTTGGAG
ATGACGCCGCCTCAAGTACGCGAGCTGTTGGTACGGGTGCCCCGCTCGGTTTCTCTGGAAACCAAGGTGGGCAAAGACAA
GGACACCGAACTGGGGGATTTGCTGGAAACTGACGACATTTCTCCAGAAGAGACCATGATGCGGGAAGCCCTGCATCGCG
ATCTACAGCAGTTGCTCTCGGATCTCACCAGCCGCGAGCGGGATGTGATCCGCATGCGTTTCGGCTTGGGGGATGGGCGC
ACCTATTCGCTGGCGGAAATCGGTCGCGCCTTGGATCTGTCGCGGGAACGGGTGCGGCAAATTGAGGCCAAAGCTCTGCA
GAAGTTGCGTCAGCCGAAGCGGCGCAACCGCGTGCGAGATTACCTGGAAGCTATCAGCTAG

Upstream 100 bases:

>100_bases
CGTTGGGGAACACTTAAGCTTAACTTGCTCCACATCACTGACCATTCCTCTCTCAGCCCACTGAACTGCTACCTCTGTCG
CTACATCAGCAACACCCTAC

Downstream 100 bases:

>100_bases
TTCCGGCTTGCCAACTTGCTCCCCCGGCGTCCTACCCGTTTCCGCAGTTGGGCTGCTGCCCACTCCACTTCTGGGATCCG
CAGGTAGAGAGCTCCGGCGG

Product: RNA polymerase sigma factor SigC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSNYEPELNDILLDGPADLLEAAEEAEVDLADGEFLEEEPTRRSTDLVRLYLQEIGRVPLLGRDEEVALAQKVQDYMKLL
DLRLRLQKELGRDPTLAEWVAKANQYPEWAQLTPEKLQQIQRIGKRAKEHMIKANLRLVVSVAKKYQNRGLELLDLIQEG
TLGLERAVEKFDPKKGYRFSTYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKLSQEKGRTPTIEDIASELE
MTPPQVRELLVRVPRSVSLETKVGKDKDTELGDLLETDDISPEETMMREALHRDLQQLLSDLTSRERDVIRMRFGLGDGR
TYSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRDYLEAIS

Sequences:

>Translated_366_residues
MSNYEPELNDILLDGPADLLEAAEEAEVDLADGEFLEEEPTRRSTDLVRLYLQEIGRVPLLGRDEEVALAQKVQDYMKLL
DLRLRLQKELGRDPTLAEWVAKANQYPEWAQLTPEKLQQIQRIGKRAKEHMIKANLRLVVSVAKKYQNRGLELLDLIQEG
TLGLERAVEKFDPKKGYRFSTYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKLSQEKGRTPTIEDIASELE
MTPPQVRELLVRVPRSVSLETKVGKDKDTELGDLLETDDISPEETMMREALHRDLQQLLSDLTSRERDVIRMRFGLGDGR
TYSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRDYLEAIS
>Mature_365_residues
SNYEPELNDILLDGPADLLEAAEEAEVDLADGEFLEEEPTRRSTDLVRLYLQEIGRVPLLGRDEEVALAQKVQDYMKLLD
LRLRLQKELGRDPTLAEWVAKANQYPEWAQLTPEKLQQIQRIGKRAKEHMIKANLRLVVSVAKKYQNRGLELLDLIQEGT
LGLERAVEKFDPKKGYRFSTYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKLSQEKGRTPTIEDIASELEM
TPPQVRELLVRVPRSVSLETKVGKDKDTELGDLLETDDISPEETMMREALHRDLQQLLSDLTSRERDVIRMRFGLGDGRT
YSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRDYLEAIS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=270, Percent_Identity=47.7777777777778, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI1789098, Length=329, Percent_Identity=37.9939209726444, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789871, Length=241, Percent_Identity=30.7053941908714, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788231, Length=206, Percent_Identity=27.1844660194175, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR017848
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 42373; Mature: 42242

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYEPELNDILLDGPADLLEAAEEAEVDLADGEFLEEEPTRRSTDLVRLYLQEIGRVPL
CCCCCCCHHHEEECCCHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCC
LGRDEEVALAQKVQDYMKLLDLRLRLQKELGRDPTLAEWVAKANQYPEWAQLTPEKLQQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHCCHHHHHHH
QRIGKRAKEHMIKANLRLVVSVAKKYQNRGLELLDLIQEGTLGLERAVEKFDPKKGYRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCH
TYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKLSQEKGRTPTIEDIASELE
HHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
MTPPQVRELLVRVPRSVSLETKVGKDKDTELGDLLETDDISPEETMMREALHRDLQQLLS
CCCHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLTSRERDVIRMRFGLGDGRTYSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRD
HHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YLEAIS
HHHHCC
>Mature Secondary Structure 
SNYEPELNDILLDGPADLLEAAEEAEVDLADGEFLEEEPTRRSTDLVRLYLQEIGRVPL
CCCCCCHHHEEECCCHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCC
LGRDEEVALAQKVQDYMKLLDLRLRLQKELGRDPTLAEWVAKANQYPEWAQLTPEKLQQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHCCHHHHHHH
QRIGKRAKEHMIKANLRLVVSVAKKYQNRGLELLDLIQEGTLGLERAVEKFDPKKGYRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCH
TYAYWWIRQGITRAIATQSRTIRLPVHITEKLNKIKKAQRKLSQEKGRTPTIEDIASELE
HHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
MTPPQVRELLVRVPRSVSLETKVGKDKDTELGDLLETDDISPEETMMREALHRDLQQLLS
CCCHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DLTSRERDVIRMRFGLGDGRTYSLAEIGRALDLSRERVRQIEAKALQKLRQPKRRNRVRD
HHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YLEAIS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385387; 11759840 [H]